The cheapest and fastest trains from St. Louis, MO to Buffalo, NY
Cheapest price
$179
Average price
$179
Fastest journey
16 h 58 m
Average duration
16 h 58 m
Trains per day
1
Distance
1063 km
The best way to find a cheap train ticket from St. Louis, MO to Buffalo, NY is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from St. Louis, MO to Buffalo, NY will cost around $179 if you buy it on the day, but the cheapest tickets can be found for only $179.
Of the 1 trains that leave St. Louis, MO for Buffalo, NY on Thu, Feb 26, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Thu, Feb 26 the direct trains cover the 1063 km distance in an average of 16 h 58 m but if you time it right, some trains will get you there in just 16 h 58 m .
On Thu, Feb 26 the slowest trains will take 16 h 58 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Travel Information
Compare train, bus, and flight for St. Louis, MO to Buffalo, NY
Omio recommends booking the train as it is the most popular option from St. Louis, MO to Buffalo, NY among Omio's users. If you are prioritising price take the bus with prices starting from $119. For those with little time consider booking a flight which can get you there in 6h 16m. The ticket price range depends on the travel mode: a bus costs an average of $119, and a flight costs an average of $101.
Distance: 660 miles (1063 km)
Compare train with
Most popular Train | Flight | Bus |
|---|---|---|
$236 Average price | $320 Average price | $194 Average price Cheapest |
16h 28m Average total duration 15h 58m Onboard + 30m Additional time* | 9h 16m Average total duration Fastest 6h 16m Onboard + 3h 0m Additional time* | 26h 50m Average total duration 26h 20m Onboard + 30m Additional time* |
Direct Options | Direct Options | Direct Options |
Compare prices and tickets St. Louis, MO to Buffalo, NY by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Feb 26
Feb 27
Feb 28
Mar 01
Mar 02
Mar 03
Mar 04
Journey information
Overview: Train from St. Louis, MO to Buffalo, NY
Trains from St. Louis, MO to Buffalo, NY run on average 3 times per day, taking around 15h 58m. Cheap train tickets for this journey start at $96 (€76) if you book in advance.
The earliest train runs at 00:39, the last at 14:55. The fastest train covers the 660 miles (1063 km) distance in 16h 58m.
Distance 660 miles (1063 km) |
Average train duration 15h 58m |
Cheapest ticket price $96 (€76) |
Trains per day 3 |
Fastest train 16h 58m |
First train 00:39 |
Last train 14:55 |
Train companies: Amtrak from St. Louis, MO to Buffalo, NY trainsAmtrak trains will get you between St. Louis, MO and Buffalo, NY from $96 (€76). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Amtrak
FAQs: Trains from St. Louis, MO to Buffalo, NY
Find answers to the most common questions about traveling from St. Louis, MO to Buffalo, NY by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Buffalo, NY, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from St. Louis, MO to Buffalo, NY
- 5:30 AM - 10:00 PM Monday - Sunday
- Free
- Parking is available on-site with both short-term and long-term options.
- Landry's Seafood House
- The Station Grille
- Outside the main entrance.
- Ramps, restrooms.
- $1
- St. Louis Union Station Hotel, Curio Collection by Hilton
- Courtyard St. Louis Downtown West
- Drury Inn St. Louis at Union Station
- Located in the main hall
- Avis
- Enterprise
- Hertz
- Located in the main hall
- Free
- Hall 1: main entrance, platform 1-4 for Amtrak and regional trains
- Hall 2: MetroLink connections
- MetroLink: Red Line, Blue Line
- Bus: Several lines available including 40, 94, 97
Most popular train connections from St. Louis, MO
More options for your journey from St. Louis, MO to Buffalo, NY
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