- Must visit
The Children's Museum of Indianapolis
World-class children's museum with science, history, dinosaurs, sports, and immersive exhibits. One of Indianapolis's signature attractions for all ages.
Omio recommends booking the bus as it is the most popular option from Boston, MA to Indianapolis, IN among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $195 For those with little time, consider booking a flight, which has an average total journey time of 6h 48m. Average ticket prices depend on the travel mode: a bus costs an average of $195, while a flight costs an average of $652.
Distance: 805 miles (1296 km)
| Train | Most popular Bus | Flight | Driving |
|---|---|---|---|
$636 Average price | $195 Average price Cheapest | $652 Average price | $252 Average price (fuel + tolls) |
28h 15m Average total duration 27h 45m Onboard + 30m Additional time* | 22h 40m Average total duration 22h 10m Onboard + 30m Additional time* | 6h 48m Average total duration Fastest 4h 48m Onboard + 2h 0m Additional time* | 13h 56m Average total duration (door-to-door) |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Boston, MA to Indianapolis, IN:
A bus is $441 less than a train for this route with tickets for a train from Boston, MA to Indianapolis, IN costing on average $636.
A bus is $457 less than a flight for this route with tickets for a flight from Boston, MA to Indianapolis, IN costing on average $652.
Other travel options to Indianapolis, IN take longer:
Bus takes on average 22h 10m.
Train takes on average 27h 45m.
Tickets start at around $636 compared to roughly $252 in fuel and tolls — a saving of about $-384.29. The journey takes 27h 45m versus 13h 56m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
The table below shows live departures for Boston, MA to Indianapolis, IN trains for today, Saturday, August 29. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
65 Northeast Regional · 51 Cardinal | 6:45 PM South Station, Boston, MA | 35h10 | 5:55 AM Indianapolis Station, Indianapolis, IN | 1 transfer | |
65 Northeast Regional · 51 Cardinal | 6:51 PM Back Bay station, Boston, MA | 35h04 | 5:55 AM Indianapolis Station, Indianapolis, IN | 1 transfer | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Trains from Boston, MA to Indianapolis, IN run on average 3 times per day, taking around 27h 45m. Cheap train tickets for this journey start at $129 but you can travel from only $121 by bus.
The earliest train runs at 00:15, the last at 18:51. The fastest train covers the 805 miles (1296 km) distance in 26h 14m.
Distance 805 miles (1296 km) |
Average train duration 27h 45m |
Cheapest ticket price $129 |
Trains per day 3 |
Fastest train 26h 14m |
First train 12:15 AM |
Last train 6:51 PM |
Cheapest Month Jun |
Cheapest Day Wed |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Sun |
Least Busy Day Sun |
Discover the best of Indianapolis, IN — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Indianapolis, IN trip today.
World-class children's museum with science, history, dinosaurs, sports, and immersive exhibits. One of Indianapolis's signature attractions for all ages.
Leading art museum set on the Newfields campus, with major collections from Europe, Asia, Africa, and America plus temporary exhibitions.
Museum and restored home of the 23rd U.S. president. Guided visits reveal politics, domestic life, and architecture from the late 1800s.
Pedestrian-friendly downtown canal lined with museums, public art, and boats. Ideal for a scenic walk and one of the city's most popular areas.
Historic city center surrounding the Soldiers and Sailors Monument. A signature urban space for architecture, events, and classic downtown views.
Popular cultural trail linking downtown districts with public art, bike lanes, and green streetscape design. Perfect for exploring the city on foot.
Indiana pork tenderloin sandwich is a breaded, fried cutlet served on a bun, often comically oversized. It is a beloved statewide classic common in Indianapolis pubs and diners.
Sugar cream pie is Indiana's state pie, made with cream, sugar, and nutmeg. Its simple farm-pantry origins make it a traditional Hoosier dessert tied closely to local identity.
Shrimp cocktail in Indianapolis style features chilled shrimp with very spicy tomato-horseradish sauce. St. Elmo made this fiery version a city dining icon.
Established fine-dining restaurant serving seasonal Midwestern cuisine with polished service. Known for refined plates and a warm, contemporary atmosphere.
Historic downtown steakhouse famous for aged steaks and the city's iconic fiery shrimp cocktail. Classic, upscale atmosphere with longstanding local prestige.
Long-running Indianapolis institution known for classic steaks, seafood, and old-school service. A traditional downtown choice with historic local character.
Moderate for a U.S. city: hotels and dining are mid-range, while transit is limited so many visitors use rideshare or rental cars.
Tip 18-20% at restaurants, $1-$2 per drink at bars, and 10-15% for taxis. Small cafe tips are appreciated but optional.
Find answers to the most common questions about traveling from Boston, MA to Indianapolis, IN by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Indianapolis, IN, this guide helps you travel smarter and with confidence.

Most Boston, MA to Indianapolis, IN trains use the South Station to Indianapolis Station station pair. Use this guide to compare Boston, MA and Indianapolis, IN train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
South Station has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, Information Desk, and Luggage Carts.
Food options include: Legal Sea Foods, Tavern in the Square
Free. ATMs are available in the train station.
Ticket office support is available at South Station. Information desks are located in the main hall.
Luggage storage is available at South Station. Lost and found is available at the station.
Available at South Station: Parking, Taxis, WC.
Available at South Station: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at South Station: Elevators, restrooms.
Nearby hotels include InterContinental Boston, The Langham, Boston, Boston Harbor Hotel.
Back Bay Station is 1 km from Boston city centre. Public transport options include:
Back Bay Station has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, Information Desk, and Luggage Carts.
Food options include: Sorellina, Atlantic Fish Company
Free. ATMs are available in the train station.
Ticket office support is available at Back Bay Station. Information desks are located in the main hall.
Luggage storage is available at Back Bay Station. Lost and found is available at the station.
Available at Back Bay Station: Parking, Taxis, WC.
Available at Back Bay Station: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Back Bay Station: Elevators, ramps, restrooms.
Nearby hotels include Copley Square Hotel, The Westin Copley Place, Fairmont Copley Plaza.
Indianapolis Station has practical services for this route, including Wifi, Parking, Dining, Taxis, Accessibility, WC, Hotel, Ticket Office, Bike Parking, Information Desk, and Luggage Carts.
Food options include: Harry & Izzy's, St. Elmo Steak House
Free.
Ticket office support is available at Indianapolis Station. Information desks are located in the main hall.
Available at Indianapolis Station: Parking, Taxis, WC.
Available at Indianapolis Station: Bike Parking.
Accessibility facilities are available at Indianapolis Station: Ramps.
Nearby hotels include Crowne Plaza Indianapolis-Dwtn-Union-Stn, Omni Severin Hotel, The Westin Indianapolis.
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