- Must visit
Royal Museums of Fine Arts of Belgium
Major national museum complex with Old Masters, Magritte, and modern collections; one of Brussels' key art institutions.
2,000+ travel companies
2,000+ travel companies
Scan to get our free app
Use our app to get live travel updates and book mobile tickets for trains, buses, flights, and ferries.
App Store
4.942K ratings
Google Play
4.6136K reviews
The cheapest and fastest trains from Lyon to Brussels
Showing times and prices for May 18
Cheapest price
$215
Average price
$257
Fastest journey
3 h 56 m
Average duration
4 h 9 m
Trains per day
17
Distance
569 km
Cheap tickets
The best way to find a cheap train ticket from Lyon to Brussels is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Lyon to Brussels will cost around $257 if you buy it on the day, but the cheapest tickets can be found for only $215.
Fast trains
Of the 17 trains that leave Lyon for Brussels on Mon, May 18, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Mon, May 18 the direct trains cover the 569 km distance in an average of 4 h 9 m but if you time it right, some trains will get you there in just 3 h 56 m .
On Mon, May 18 the slowest trains will take 4 h 18 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
6922+
93935:54 PM4h53Lyon Saint-Exupéry TGV10:47 PMBrussels-Midi$2151One-way1 transfer- 6624+93774:04 PM4h18Lyon Part Dieu8:22 PMBrussels-Midi$2151One-way1 transfer
- 6624+93773:50 PM4h32Gare de Lyon-Perrache8:22 PMBrussels-Midi$2151One-way1 transfer
- 6628+93936:04 PM4h43Lyon Part Dieu10:47 PMBrussels-Midi$2291One-way1 transfer
- 6628+93935:50 PM4h57Gare de Lyon-Perrache10:47 PMBrussels-Midi$2291One-way1 transfer
98685:00 PM3h56Lyon Part Dieu8:56 PMBrussels-Midi$2301One-way0 transfers- 6696+93875:38 PM4h06Lyon Part Dieu9:44 PMBrussels-Midi$2301One-way1 transfer
- 6690+94237:04 AM4h13Lyon Part Dieu11:17 AMBrussels-Midi$3551One-way1 transfer
- 6622+94713:04 PM4h13Lyon Part Dieu7:17 PMBrussels-Midi$2771One-way1 transfer
- 6194+94297:59 AM4h18Lyon Saint-Exupéry TGV12:17 PMBrussels-Midi$2771One-way1 transfer
Travel Information
Compare train, bus, and flight for Lyon to Brussels
Omio recommends booking the train as it is the most popular option from Lyon to Brussels among Omio's users. If you are prioritising price take the bus with prices starting from $27. For those with little time consider booking a flight which can get you there in 2h 25m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.5kg. The ticket price range depends on the travel mode: a bus costs an average of $27, and a flight costs an average of $113.
Distance: 353 miles (569 km)
Compare train with
Most popular Train | Bus | Flight | Driving |
|---|---|---|---|
$163 Average price | $59 Average price Cheapest | $311 Average price | $197 Average price (fuel + tolls) |
5h 17m Average total duration 4h 47m Onboard + 30m Additional time* | 8h 29m Average total duration 7h 59m Onboard + 30m Additional time* | 5h 25m Average total duration Fastest 2h 25m Onboard + 3h 0m Additional time* | 7h 28m Average total duration (door-to-door) |
0.2 - 0.5kg CO2 emissions Lowest | 0.6 - 1.4kg CO2 emissions | 1.7 - 3.4kg CO2 emissions | - CO2 emissions |
Most popular train company |  Most popular bus company |  Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
The cheapest way to travel from Lyon to Brussels is a bus with an average price of $59 (€48).
This is compared to other travel options from Lyon to Brussels:
A bus is $103 (€84) less than a train for this route with tickets for a train from Lyon to Brussels costing on average $163 (€131).
A bus is $252 (€204) less than a flight for this route with tickets for a flight from Lyon to Brussels costing on average $311 (€251).
The fastest way to travel from Lyon to Brussels is by flight with an average journey time of 2h 25m.
Other travel options to Brussels take longer:
Train takes on average 4h 47m.
Bus takes on average 7h 59m.
It's helpful to compare your options as there are 3 ways to travel between Lyon and Brussels including taking a train, bus, and flight.
We recommend using the train as it is the most popular way to get from Lyon to Brussels among Omio's users.
Take the train. On this route, it beats driving on both time and money.
The journey is about 2h 41m faster (4h 47m by train vs 7h 28m by car) and roughly $35 (€28) cheaper once you factor in fuel and tolls ($163 (€131) vs $197 (€159)). You'll also arrive in the city centre rather than hunting for parking, and you can work, read, or watch the landscape go by instead of concentrating on the road.
Direct services run with SNCF | TGV INOUI, TGV.
Driving is still worth considering if you want to stop along the way or need a car once you arrive.
Live departures
Lyon to Brussels train times
The table below shows live departures for Lyon to Brussels trains for today, Sunday, May 17. You can also manually refresh the results below to see updated train journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| 1:00 PM Lyon | 3h55 | 4:55 PM Brussels | 0 transfersDirect | |
| 3:00 PM Lyon | 3h56 | 6:56 PM Brussels | 0 transfersDirect | |
| 6:00 PM Lyon | 3h56 | 9:56 PM Brussels | 0 transfersDirect | |
| Monday, May 18 | |||||
| 6902+9423 | 6:54 AM Lyon Saint-Exupéry TGV | 4h23 | 11:17 AM Brussels-Midi | 1 transfer | |
| 6690+9423 | 7:04 AM Lyon Part Dieu | 4h13 | 11:17 AM Brussels-Midi | 1 transfer | |
| 6194+9329 | 7:59 AM Lyon Saint-Exupéry TGV | 4h18 | 12:17 PM Brussels-Midi | 1 transfer | |
| 6194+9429 | 7:59 AM Lyon Saint-Exupéry TGV | 4h18 | 12:17 PM Brussels-Midi | 1 transfer | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Lyon to Brussels by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Sun
May 17
May 17
Mon
May 18
May 18
Tue
May 19
May 19
Wed
May 20
May 20
Thu
May 21
May 21
Fri
May 22
May 22
Sat
May 23
May 23
Sun
May 24
May 24
Mon
May 25
May 25
Tue
May 26
May 26
Wed
May 27
May 27
Thu
May 28
May 28
Fri
May 29
May 29
Sat
May 30
May 30
Sun
May 31
May 31
Mon
Jun 01
Jun 01
Tue
Jun 02
Jun 02
Wed
Jun 03
Jun 03
Thu
Jun 04
Jun 04
Fri
Jun 05
Jun 05
Sat
Jun 06
Jun 06
How far in advance should I book train tickets from Lyon to Brussels?
The best time to book your train from Lyon to Brussels is 77 days before departure. See how prices for trains change on the Lyon to Brussels route.
Prices are for one-way tickets for one passenger from Lyon to Brussels per month. Insights are sourced from fares found by Omio users in the last 12 months. Current prices may differ as prices vary depending on the time of day, class or how far in advance you book your train from Lyon to Brussels.
Trains
from $111Buses
from $41Flights
from $179Journey information
Overview: Train from Lyon to Brussels
France
Belgium
Trains from Lyon to Brussels run on average 4 times per day, taking around 4h 47m. Cheap train tickets for this journey start at $93 (€75) but you can travel from only $27 (€22) by bus.
There are 4 trains per day. The earliest train runs at 00:15, the last at 19:16. The fastest train covers the 353 miles (569 km) distance in 3h 53m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $27 (€22)
Distance 353 miles (569 km) |
Average train duration 4h 47m |
Cheapest ticket price $93 (€75) |
Trains per day 4 |
Direct trains 4 |
Fastest train 3h 53m |
First train 12:15 AM |
Last train 7:16 PM |
Cheapest Month Feb |
Cheapest Day Tue |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Wed |
Least Busy Day Sun |
Best time to book 56 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $27 (€22)
Train companies: SNCF | TGV INOUI, TGV from Lyon to Brussels trainsSNCF | TGV INOUI, TGV trains will get you between Lyon and Brussels from $27 (€22). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
SNCF | TGV INOUI
About
SNCF's TGV INOUI is a premium high-speed train service operating across France and to other European cities. Launched in 2017, it aims to provide an enhanced travel experience with greater comfort, connectivity, and services compared to traditional TGV services. TGV INOUI trains offer features like adjustable seats, electrical outlets, fold-down tables, and dedicated luggage spaces. Passengers can enjoy onboard Wi-Fi and access to the TGV INOUI portal for entertainment and journey information. The service also includes a "Bistro TGV INOUI" for dining, with options for online ordering. SNCF is also introducing a new generation of TGV INOUI trains from 2026, which will be more modular, energy-efficient, and 97% recyclable.
Luggage & cancellation policy
Average Duration
3h 53m
Cheapest Price
$93 (€75)
SNCF | TGV INOUI frequency
8 a day
Luggage included
1 hand luggage + 2 pieces of luggage free of charge
Luggage storage
Overhead racks, end of carriages, between seats
Cancellation Policy
Refund conditions depend on ticket type
Refund
Full refund if train canceled
Amenities on board the train
Wifi
Food sold onboard
Restaurant car (not all trains), at-seat service in 1st class, snack bar/cafe
Seat reservation
Second class: Optional, additional fee. First class: Included in ticket price
Toilets
USB plugs
Accessibility
Wheelchair spaces, accessible toilets, boarding assistance available
Pets
Small pets in carriers: Free. Large dogs: Paid ticket required. Guide dogs: Free
Quiet zone
TGV
About
TGV is a high-speed train company based in France. It operates a fleet of modern trains that can reach speeds of up to 320 km/h. The TGV offers a variety of train types, including the TGV Duplex, TGV Lyria, TGV InOui, and TGV OuiGo. Each train type provides different amenities, such as Wi-Fi, power outlets, and comfortable seating. Ticket options include Standard, Flexi, and Prem’s. Onboard facilities feature a bar, restaurant, and luggage storage. Popular TGV routes include Paris to Lyon, Paris to Marseille, and Paris to Lille.
Luggage & cancellation policy
Average Duration
3h 41m
Cheapest Price
$85 (€69)
TGV frequency
6 a day
Luggage included
2 pieces of hand luggage and 1 suitcase included in ticket price
Luggage storage
Dedicated luggage areas at end of carriages and overhead racks
Cancellation Policy
According to fare conditions and ticket type
Refund
Full refund provided for canceled trains
Amenities on board the train
Wifi
Food sold onboard
Restaurant car with full meals and bar service, at-seat dining in first class
Seat reservation
Included in first class, optional fee in second class
Toilets
USB plugs
Accessibility
Wheelchair spaces, accessible toilets, and assistance service available
Pets
Small pets in carriers travel free, larger dogs require paid ticket, guide dogs travel free
Quiet zone
Complete guide to Brussels
Things to do in Brussels
Discover the best of Brussels — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Brussels trip today.
- Must visit
Magritte Museum
Dedicated to René Magritte, with the world's largest collection of his works in a central historic building.
- Recommended
BELvue Museum
Interactive museum on Belgian history and society, useful for understanding the country beyond Brussels landmarks.
- Must visit
Mont des Arts
Landscaped cultural quarter and viewpoint linking upper and lower town, especially popular for skyline photos.
- Must visit
Galeries Royales Saint-Hubert
Elegant 19th-century glass-roofed arcade known for architecture, shopping, and frequent social media coverage.
- Recommended
Place du Grand Sablon
Stylish square surrounded by historic buildings, antiques, and galleries; one of the city's most atmospheric areas.
- Gluten-free
Moules-Frites
Mussels steamed with white wine, celery, and herbs, served with fries. A classic Belgian brasserie dish strongly associated with Brussels.
Carbonnade Flamande
A rich Flemish beef and onion stew slow-cooked with Belgian beer. It is a beloved comfort dish commonly served in traditional Brussels restaurants.
- Vegetarian
- Gluten-free
Stoemp
A rustic mash of potatoes with seasonal vegetables such as carrots or leeks, often served as a side or with sausage. It is a staple of Brussels home cooking.
Comme Chez Soi
One of Brussels’ most famous fine dining restaurants, celebrated for refined Belgian and French-inspired cuisine in an elegant Art Nouveau setting.
Nüetnigenough
Well-regarded restaurant serving traditional Belgian cuisine and a strong beer list, with a cozy atmosphere popular for carbonnade and other local specialties.
Fin de Siècle
Popular casual spot known for generous portions of Belgian comfort food, including stoemp and beer-based stews, in a busy old-school dining room.
Euro
Compared with many other European cities, Brussels is moderately high in cost for hotels and restaurant dining, though public transport and casual food remain manageable.
Average meal costs
- Budget
- EUR 10-18 for fast food, fries shops, or simple lunch spots.
- Mid-range
- EUR 25-45 per person for a main course and drink at a mid-range restaurant.
- Fine dining
- EUR 70-150+ per person at upscale restaurants, higher with wine pairing.
- Coffee
- EUR 3-5 for a cappuccino or similar coffee drink.
Tipping culture
Service is generally included in restaurant bills in Belgium, so tipping is not obligatory. Leaving 5-10% for very good service is appreciated in restaurants. In cafes and bars, rounding up or leaving
STIB-MIVB
Get the appOfficial public transport app
Prices
- Single ticket
- 2.60 EUR
- Day pass
- 8.00 EUR
To the city center
Brussels-Midi, Brussels -> Brussels-Central, Brussels
- Distance
- 2 km
- Travel time
- 5 min
- Contactless card payment is available on STIB-MIVB buses, trams, and metro validators, so you can tap in without buying a paper ticket.
- A single STIB-MIVB ticket is valid for 60 min with transfers, but SNCB train tickets are separate unless you buy a combined product.
FAQs: Trains from Lyon to Brussels
Find answers to the most common questions about traveling from Lyon to Brussels by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Brussels, this guide helps you travel smarter and with confidence.
Train ticket prices from Lyon to Brussels can vary. The cheapest ticket starts at $93 (€75), while the average price is around $163 (€131).
The train from Lyon to Brussels takes 3h 53m and runs 4 per day.
The first train from Lyon to Brussels leaves at 12:15 AM.
The distance by train from Lyon to Brussels is 353 miles (569 km).
The last train from Lyon to Brussels leaves at 7:16 PM.
Yes, there is a high-speed train from Lyon to Brussels.
Yes, there is a direct train from Lyon to Brussels. This service operates 4 times per day, provided by SNCF | TGV INOUI, TGV.
Unfortunately, there is no night train available from Lyon to Brussels.
The train station in Lyon that goes to Brussels is Lyon Part Dieu, which connects to Brussels-Midi.
The cheapest way to get from Lyon to Brussels is by bus, with a cost of around $27 (€22).
The train journey from Lyon to Brussels offers scenic views, particularly as it passes through the picturesque landscapes of the French countryside and the rolling hills of southern Belgium. Passengers can enjoy views of charming villages, lush fields, and historical architecture along the route.
A day trip from Lyon to Brussels is not feasible as the journey takes 3h 53m each way. The distance is 353 miles (569 km), with 5 trains available per day.
In Brussels, explore the vibrant Marolles district with its antique shops and street art, and enjoy a stroll through Parc du Cinquantenaire with its impressive arches and museums. Sample Belgian chocolates at the city's renowned chocolatiers, and experience the lively Saint-Géry district's trendy bars and cafes. Attend a performance at the historic La Monnaie opera house. Don't miss top sights like the opulent Grand Place, Atomium for panoramic views, the iconic Manneken Pis statue, the Royal Palace of Brussels, and the Magritte Museum.
For a fulfilling experience in Brussels, plan on spending 2 to 3 days to explore key attractions such as the Grand Place, Atomium, and various museums, as well as to enjoy the local cuisine and vibrant neighborhoods.
Yes, you can take the train from Lyon to Brussels.
Since both Lyon and Brussels are in the Schengen Area, a passport is not required for European Union (EU) or Schengen-associated country citizens. A national ID card is sufficient.
Popular day trips by train from Brussels include Bruges, Ghent, Antwerp, Lille, Rotterdam.
We recommend using the train as it is the most popular way to get from Lyon to Brussels among Omio's users.
Items not allowed on trains typically include hazardous materials such as explosives, flammable liquids, corrosive substances, and illegal drugs. Additionally, large or bulky items that may obstruct aisles or emergency exits, as well as pets without proper carriers, may be restricted. Specific prohibited items can vary by train operator and region, so please check the rules for your particular journey.
Belgium uses the euro (EUR) as its currency. Travelers generally find card payments widely accepted in cities, restaurants, and shops, though carrying some cash is advisable for small purchases or in rural areas.
In Brussels, travelers should be cautious of pickpocketing, especially in crowded areas like Grand Place, public transport, and popular tourist sites. Common scams include distraction techniques and fake petitions. It's advisable to stay vigilant, avoid displaying expensive items, and use official taxi services to ensure safety.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular train stations
Popular train stations from Lyon to Brussels
Lyon
Brussels
The major train station for departures in Lyon is Lyon Part Dieu. Find all the information you need to know about services, amenities and connections at Lyon Part Dieu for your trip from Lyon to Brussels.
Amenities at train station
Wifi
Lockers
Parking
Dining
ATM
Taxis
Accessibility
WC
Hotel
Ticket Office
Bike Parking
Bike Rental
Car Rental
Information Deskinformation
Ticket Office Hours
- Mon - Wed: 05:00 - 20:45
- Thu - Sat: 05:00 - 21:45
- Sun: 06:45 - 21:45
Distance to city center
1 kmWifi
- Free unlimited WiFi.
Lockers
- Luggage lockers are available daily from 06:15 to 23:15. They are located near the station's reception desk.
Dining
- Alto Café
- Paul
- Paul The Café
- Starbucks
- Exki
- Sushi Shop
- Carrefour
Accessibility
- Complimentary personalized care is available.
Hotel
- Radisson Blu Hotel Lyon
- Mercure Lyon Center
- ibis Styles Lyon Center
Ticket Office
- Mon - Wed: 05:00 - 20:45
- Thu - Sat: 05:00 - 21:45
- Sun: 06:45 - 21:45
Information Desk
- Located in the station's main hall.
Public transit options for Lyon Part Dieu
- Metro lines: A, B, C, D
- Tram lines: T4, K240, T3, K100
- Bus lines: 2960, C2, C3, C6, C9
- Train lines: TGV, TGV Lyria, TGV INOUI, OUIGO, TER, Intercités, Eurostar, AVE
Amenities at train station
WifiParkingDiningATMTaxisAccessibilityWCHotelTicket OfficeBike ParkingBike RentalCar RentalInformation Deskinformation
Ticket Office Hours
- Mon - Fri: 10:00 - 18:00
Distance to city center
1 kmWifi
- Free, unlimited Wi-Fi is available after creating an account and connecting to "CONNECTION."
Dining
- PAUL
Accessibility
- Hearing, mobility, and visual disability assistance. Accessibility available with elevator, ramp or step-free access, barrier-free toilets.
Hotel
- Mercure Lyon Centre Chateau Perrache
- Hotel De Normandie
- InterContinental Lyon-Hotel Dieu
Ticket Office
- Mon - Fri: 10:00 - 18:00
Information Desk
- Information services are available at the ticket office, located in Hall Level 2.
Public transit options for Lyon-Perrache
- Metro lines: A, B, C, D
- Bus lines: 8, 31, 46, 49, 55, 60, 63, S1, C19, C21, C22
- Tram lines: 1, 2
- Train lines: TGV, TGV INOUI, OUIGO, TER Auvergne-Rhône-Alpes, Intercités
Amenities at train station
WifiLockersParkingDiningATMTaxisAccessibilityWCHotel
Lost and Found OfficeTicket OfficeBike ParkingCar RentalInformation Desk
Luggage Cartsinformation
Ticket Office Hours
- 6:00 AM - 11:00 PM Monday - Sunday
Distance to city center
3 km
Number of platforms
4Wifi
- Free
Parking
- The car park is open 7 days a week. Access is available via Rue de Grèce.
Dining
- Restaurant Moxy Lyon Airport
- NH Lyon Airport Restaurant
Taxis
- Outside the main entrance.
Accessibility
- Elevators, ramps, restrooms.
WC
- €0.50
Hotel
- Moxy Lyon Airport
- NH Lyon Airport
- Ibis Budget Aéroport Lyon Saint Exupéry
Lost and Found Office
- Located in the main hall
Bike Parking
- 150 places, covered
Car Rental
- Avis
- Europcar
- Hertz
Information Desk
- Located in the main hall
Luggage Carts
- Free
Station Plan
- Hall 1: main entrance, platform access
- Hall 2: ticket office and services
- Hall 3: connection to Lyon-Saint Exupéry Airport
Public transit options for Lyon Saint-Exupéry TGV
- Tramway: Rhônexpress
- Bus: Several lines available
The major train station for arrivals in Brussels is Bruxelles-Midi. Find all the information you need to know about services, amenities and connections at Bruxelles-Midi for your journey to Brussels from Lyon.
Amenities at train station
WifiLockersParkingDiningATMTaxisAccessibilityWCHotelTicket OfficeBike ParkingBike RentalCar RentalInformation Deskinformation
Ticket Office Hours
- Mon - Sun: 05:45 - 21:30
Wifi
- Wi-Fi is available for a fee.
Lockers
- Baggage storage facility is located across from the Thalys business lounge.
Dining
- Pullman Hotel Bar
- Quick Gare du Midi
- Subway
- EXKi Zuid
- Starbucks
- Häagen-Dazs
- Sbarro
- The Coffee Club
- The Belgian Chocolate House
- PAUL
- & many more
Accessibility
- Station has a wide range of facilities for passengers with reduced mobility: elevators and escalators to all platforms, wheelchair lifts and mobile ramps, disabled toilet and parking spaces. Additional assistance can be contacted via the SNCB Mobility Call Center.
Hotel
- Les Lofts De Styliste
- Park Inn by Radisson Brussels Midi
- Pullman Brussels Centre Midi
Information Desk
- Located in the main concourse and next to the international platforms.
More options for your journey from Lyon to Brussels
Here are some other resources that might have the information you need
Most popular trains to and from Brussels and Lyon
Most popular train connections to Brussels
The Omio App Makes Travel Planning Easy
We’ll get you where you want to go. From live train updates to mobile tickets, our innovative app is the ideal way to plan and keep track of your travel.
