- Must visit
National Museum
Major museum of Czech history and natural sciences in a monumental Neo-Renaissance building overlooking Wenceslas Square.
Cheapest price
$59
Average price
$196
Fastest journey
11 h 42 m
Average duration
11 h 47 m
Trains per day
20
Distance
596 km
The best way to find a cheap train ticket from Luxembourg to Prague is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Luxembourg to Prague will cost around $196 if you buy it on the day, but the cheapest tickets can be found for only $59.
It's difficult to get from Luxembourg to Prague without transferring at least 3 times.
Bus 82158 · 4132 · EC 459
RE 5113 · ICE 29 · 3597+
363
Bus 82138 · 4118 · ICE 592 · RJ 479
RE 5111 · 4259 · ICE 625 · 3573
RE 5117 · 4110 · ICE 596 · IC 2047
RE 5109 · R 4102 · ICE 2590 · IC 2441
RE 5119 · R 4263 · ICE 1655 · NJ 457
RE 5111 · R 4259 · ICE 625 · R 3573
RE 5111 · 4259 · ICE 625 · 3573
RE 5113 · 4106 · ICE 2588 · IC 2049Omio recommends booking the bus as it is the most popular option from Luxembourg to Prague among Omio's users. If you are prioritising price take the bus with prices starting from $41. For those with little time consider booking a flight which can get you there in 2h 12m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.5kg. The ticket price range depends on the travel mode: a bus costs an average of $41, and a flight costs an average of $133.
Distance: 370 miles (596 km)
| Train | Most popular Bus | Flight | Driving |
|---|---|---|---|
$114 Average price | $58 Average price Cheapest | $234 Average price | $126 Average price (fuel + tolls) |
12h 4m Average total duration 11h 34m Onboard + 30m Additional time* | 11h 11m Average total duration 10h 41m Onboard + 30m Additional time* | 5h 12m Average total duration Fastest 2h 12m Onboard + 3h 0m Additional time* | 7h 6m Average total duration (door-to-door) |
0.2 - 0.5kg CO2 emissions Lowest | 0.6 - 1.5kg CO2 emissions | 1.8 - 3.6kg CO2 emissions | - CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Luxembourg to Prague:
A bus is $56 (€56) less than a train for this route with tickets for a train from Luxembourg to Prague costing on average $114 (€114).
A bus is $177 (€177) less than a flight for this route with tickets for a flight from Luxembourg to Prague costing on average $234 (€234).
Other travel options to Prague take longer:
Bus takes on average 10h 41m.
Train takes on average 11h 34m.
Tickets start at around $114 (€114) compared to roughly $126 (€126) in fuel and tolls — a saving of about $12 (€12). The journey takes 11h 34m versus 7h 6m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
The table below shows live departures for Luxembourg to Prague trains for today, Monday, July 27. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
RE 5125 · IC 2041 · ICE 947 · rj 479 | On time 3:33 PM Luxembourg station | 13h52 | 5:25 AM Prague hlavní nádraží | 3 transfers | |
RE 5125 · IC 2041 · ICE 947 · rj 479 | On time 3:33 PM Luxembourg station | 13h52 | 5:25 AM Prague hlavní nádraží | 3 transfers | |
RE 5125 · IC 2041 · ICE 947 · RJ 479 | On time 3:33 PM Luxembourg station | 13h52 | 5:25 AM Prague hlavní nádraží | 3 transfers | |
RE 5125 · IC 2041 · ICE 947 · rj 479 | On time 3:33 PM Luxembourg station | 13h52 | 5:25 AM Prague hlavní nádraží | 3 transfers | |
RE 5133 · R 4132 · EC 459 | On time 7:33 PM Luxembourg station | 13h52 | 9:25 AM Prague hlavní nádraží | 2 transfers | |
Bus 82158 · 4132 · EC 459 | On time 8:05 PM Luxembourg station | 13h20 | 9:25 AM Prague hlavní nádraží | 2 transfers | |
RE 5139 · R 4134 · RB 29501 · ICE 1555 | On time 10:33 PM Luxembourg station | 16h42 | 3:15 PM Prague-Holešovice | 4 transfers | |
| Tuesday, July 28 | |||||
R 5107 · ICE 25 · R 3567 · EC 359 | 6:10 AM Luxembourg station | 12h11 | 6:21 PM Prague hlavní nádraží | 3 transfers | |
RE 5109 · ICE 27 · R 3571 · EC 361 | On time 7:33 AM Luxembourg station | 12h48 | 8:21 PM Prague hlavní nádraží | 3 transfers | |
RE 5109 · R 4102 · ICE 2590 · IC 2441 | On time 7:33 AM Luxembourg station | 11h42 | 7:15 PM Prague-Holešovice | 4 transfers | |
RE 5111 · R 4259 · ICE 1651 · rj 385 | On time 8:33 AM Luxembourg station | 12h52 | 9:25 PM Prague hlavní nádraží | 3 transfers | |
RE 5111 · 4259 · ICE 625 · 3573 | On time 8:33 AM Luxembourg station | 11h48 | 8:21 PM Prague hlavní nádraží | 4 transfers | |
RE 5111 · R 4259 · ICE 625 · R 3573 | On time 8:33 AM Luxembourg station | 11h48 | 8:21 PM Prague hlavní nádraží | 4 transfers | |
Bus 82122 · ICE 1651 · S1 · 28012 | On time 9:15 AM Luxembourg station | 11h55 | 9:10 PM Prague hlavní nádraží | 5 transfers | |
Bus 82122 · ICE 1651 · RJ 385+ TGV 9551 | On time 9:15 AM Luxembourg station | 12h10 | 9:25 PM Prague hlavní nádraží | 3 transfers | |
RE 5113 · 4106 · ICE 2588 · IC 2049 | On time 9:33 AM Luxembourg station | 11h52 | 9:25 PM Prague hlavní nádraží | 4 transfers | |
RE 5113 · R 4106 · ICE 2588 · IC 2049 | On time 9:33 AM Luxembourg station | 11h52 | 9:25 PM Prague hlavní nádraží | 4 transfers | |
RE 5113 · ICE 29 · R 3575 · EC 363 | On time 9:33 AM Luxembourg station | 12h49 | 10:22 PM Prague hlavní nádraží | 3 transfers | |
RE 5113 · ICE 29 · 3597+ 363 | On time 9:33 AM Luxembourg station | 12h49 | 10:22 PM Prague hlavní nádraží | 3 transfers | |
RE 5115 · R 4261 · ICE 1653 · rj 179 | On time 10:33 AM Luxembourg station | 12h58 | 11:31 PM Prague hlavní nádraží | 3 transfers | |
RE 5117 · 4110 · ICE 596 · IC 2047 | On time 11:33 AM Luxembourg station | 11h58 | 11:31 PM Prague hlavní nádraží | 4 transfers | |
RE 5117 · R 4110 · ICE 596 · IC 2047 | On time 11:33 AM Luxembourg station | 11h58 | 11:31 PM Prague hlavní nádraží | 4 transfers | |
RE 5119 · R 4263 · ICE 1655 · NJ 457 | On time 12:33 PM Luxembourg station | 11h43 | 12:16 AM Prague-Holešovice | 3 transfers | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Trains from Luxembourg to Prague run on average 6 times per day, taking around 11h 34m. Cheap train tickets for this journey start at $59 (€59) but you can travel from only $41 (€41) by bus.
The earliest train runs at 00:30, the last at 23:54. The fastest train covers the 370 miles (596 km) distance in 11h 42m.
Distance 370 miles (596 km) |
Average train duration 11h 34m |
Cheapest ticket price $59 (€59) |
Trains per day 6 |
Fastest train 11h 42m |
First train 12:30 AM |
Last train 11:54 PM |
Cheapest Month Jul |
Cheapest Day Mon |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Wed |
Least Busy Day Sun |
Best time to book 63 days |
Discover the best of Prague — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Prague trip today.
Major museum of Czech history and natural sciences in a monumental Neo-Renaissance building overlooking Wenceslas Square.
Well-curated Jewish history museum across several historic sites. Important for understanding Prague's Jewish heritage and resilience.
Leading Czech art museum with medieval to modern works in a grand historic palace. Essential for fine art and decorative arts lovers.
Historic square at Prague's core, surrounded by Gothic and Baroque landmarks. A must for first-time visitors and classic city views.
Lively boulevard of Czech modern history, lined with shops and major buildings. Worth visiting for atmosphere and historic significance.
Romantic quarter of palaces, lanes, and church domes beneath Prague Castle. Ideal for wandering, photography, and quieter historic charm.
Slow-braised beef in a creamy root-vegetable sauce, usually served with bread dumplings. A classic Czech Sunday dish strongly linked to Bohemian home cooking.
Crisp roasted pork knuckle, often served with mustard, horseradish, and pickles. A hearty pub staple popular with Czech beer culture.
Roast pork with sauerkraut and dumplings. This iconic Czech combination is a cornerstone of traditional pub and family meals.
Traditional Czech restaurant and brewery by Prague Castle, praised for roast meats, dumplings, and polished historic interiors.
Upscale restaurant focused on Czech ingredients and game, with sophisticated service in an Art Nouveau municipal house setting.
Elegant Michelin-starred restaurant known for modern Czech tasting menus in a refined setting near the Vltava.
Moderate for Europe: transit is cheap, casual meals are reasonable, and hotels in the center can raise daily costs in peak season.
Service is often not included. Tip about 5-10% in restaurants, round up for cafes, and round up or add about 10% for taxis if service is good.
Official public transport app
Praha hlavní nádraží -> Václavské náměstí, Prague
Find answers to the most common questions about traveling from Luxembourg to Prague by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

Most Luxembourg to Prague trains use the Luxembourg to Praha hlavní nádraží station pair, with some services arriving at Praha Masarykovo Nádraží. Use this guide to compare Luxembourg and Prague train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
Luxembourg is 1 km from Luxembourg city centre. Public transport options include:
Luxembourg has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, Information Desk, and Luggage Carts.
Food options include: Brasserie Schuman, Vapiano Luxembourg Gare
Free. ATMs are available in the train station.
Ticket office support is available at Luxembourg. Information desks are located in the main hall.
Luggage storage is available at Luxembourg. Lost and found is available at the station.
Available at Luxembourg: Parking, Taxis, WC.
Available at Luxembourg: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Luxembourg: Elevators, ramps, restrooms.
Nearby hotels include Hotel Empire, Hotel Carlton, Park Inn by Radisson Luxembourg City.
Luxemburg, Rue de la Déportation (Gare de Hollerich) is 1 km from Luxembourg city centre. Check local transport options before travel.
Luxembourg, Gare Centrale (quai 13) is 1 km from Luxembourg city centre. Public transport options include:
Luxembourg, Gare Centrale (quai 13) has practical services for this route, including Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Bike Parking, Bike Rental, and Car Rental.
Food and drink options are available at Luxembourg, Gare Centrale (quai 13).
ATMs are available at Luxembourg, Gare Centrale (quai 13).
Available at Luxembourg, Gare Centrale (quai 13): Parking, Taxis, WC.
Available at Luxembourg, Gare Centrale (quai 13): Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Luxembourg, Gare Centrale (quai 13).
Praha hlavní nádraží is 1 km from Prague city centre. Public transport options include:
Praha hlavní nádraží has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Shower, Lounge, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, Information Desk, and Luggage Carts.
Food options include: Restaurant Fantova Kavárna, Sushi Time
Free. ATMs are available in the train station.
Ticket office support is available at Praha hlavní nádraží. Information desks are located in the main hall.
Luggage storage is available at Praha hlavní nádraží. Lost and found is available at the station.
Available at Praha hlavní nádraží: Parking, Taxis, WC.
Available at Praha hlavní nádraží: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Praha hlavní nádraží: Elevators, ramps.
Nearby hotels include Hotel Esplanade Prague, Falkensteiner Hotel Maria Prag, Hotel City Central.
Praha Masarykovo Nádraží has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, Information Desk, and Luggage Carts.
Food options include: Restaurant Kotleta, Café Imperial
Free. ATMs are available in the train station.
Ticket office support is available at Praha Masarykovo Nádraží. Information desks are located in the main hall.
Luggage storage is available at Praha Masarykovo Nádraží. Lost and found is available at the station.
Available at Praha Masarykovo Nádraží: Parking, Taxis, WC.
Available at Praha Masarykovo Nádraží: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Praha Masarykovo Nádraží: Ramps.
Nearby hotels include Hotel Kings Court, Grand Hotel Bohemia, Hotel Paris Prague.
Praha-Holesovice is 2 km from Prague city centre. Public transport options include:
Praha-Holesovice has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, Information Desk, and Luggage Carts.
Food options include: Restaurant Na Kovárně, Cross Club
Free. ATMs are available in the train station.
Ticket office support is available at Praha-Holesovice. Information desks are located in the main hall.
Luggage storage is available at Praha-Holesovice. Lost and found is available at the station.
Available at Praha-Holesovice: Parking, Taxis, WC.
Available at Praha-Holesovice: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Praha-Holesovice: Ramps, restrooms.
Nearby hotels include Mama Shelter Prague, Plaza Alta Hotel, Hotel Belvedere.
Here are some other resources that might have the information you need