- Must visit
Vatican Museums
One of the world's great museum complexes, home to vast papal collections and the Sistine Chapel. A priority visit for art, history, and Renaissance masterpieces.
Omio recommends booking the flight as it is the most popular option from Luxembourg to Rome among Omio's users. If you are prioritising price take the bus with prices starting from $73. For those with little time consider booking a flight which can get you there in 2h 26m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 1.0 - 2.5kg. The ticket price range depends on the travel mode: a bus costs an average of $73, and a flight costs an average of $107.
Distance: 614 miles (989 km)
Most popular Flight | Bus | Driving |
|---|---|---|
$264 Average price | $113 Average price Cheapest | $382 Average price (fuel + tolls) |
5h 26m Average total duration Fastest 2h 26m Onboard + 3h 0m Additional time* | 24h 46m Average total duration 24h 16m Onboard + 30m Additional time* | 13h 12m Average total duration (door-to-door) |
3.0 - 5.9kg CO2 emissions | 1.0 - 2.5kg CO2 emissions Lowest | - CO2 emissions |
![]() Most popular airline | ![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Luxembourg to Rome:
A bus is $150 (€123) less than a flight for this route with tickets for a flight from Luxembourg to Rome costing on average $264 (€217).
Other travel options to Rome take longer:
Bus takes on average 24h 16m.
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Take a train from Luxembourg to Rome and enjoy the approximately 614 miles (989 km) long journey. Find schedules and pricing options for a convenient and affordable trip.
The earliest train runs at 00:02, the last at 21:30.
Distance 614 miles (989 km) |
Trains per day 1 |
First train 12:02 AM |
Last train 9:30 PM |
High Season Oct - Dec |
Low Season Apr - Jun |
Busiest Day Fri |
Least Busy Day Sat |
Best time to book 28 days |
Discover the best of Rome — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Rome trip today.
One of the world's great museum complexes, home to vast papal collections and the Sistine Chapel. A priority visit for art, history, and Renaissance masterpieces.
A superb villa museum with Bernini sculptures and major paintings by Caravaggio, Raphael, and Titian. Timed entry is essential due to limited capacity.
The city's historic civic museums on Capitoline Hill, known for classical sculpture, ancient Roman art, and excellent views over the Forum.
A lively Baroque square with monumental fountains, elegant facades, and one of the most recognizable urban spaces in Rome.
A famous stairway and gathering point linking Piazza di Spagna with Trinita dei Monti, especially popular for photos and central city strolls.
A beloved neighborhood of narrow lanes, ivy-covered buildings, and lively Roman atmosphere, ideal for wandering day or night.
A classic Roman pasta with pecorino Romano, black pepper, and pasta water. It is one of the city’s most iconic dishes for its simplicity and bold flavor.
Traditional Roman pasta made with guanciale, egg yolk, pecorino Romano, and black pepper. It is a defining dish of Rome and is famously made without cream.
A beloved pasta sauce of tomato, guanciale, pecorino Romano, and chili. Though linked to Amatrice, it is deeply rooted in Roman trattoria cooking.
Rome’s best-known luxury fine-dining restaurant, famous for panoramic views, elegant service, and sophisticated Italian cuisine.
A historic restaurant near the Pantheon serving refined Roman classics with strong local identity. Well known for seasonal specialties and pasta.
A celebrated central Rome dining room known for Roman pasta, cured meats, and an exceptional wine list. Lively, polished, and very popular.
Moderate for Western Europe. Sights and central hotels cost more, but food, coffee, and transit can be good value.
Service is often included or modest. Locals may round up or leave EUR 1-2 at cafes; 5-10% is appreciated at restaurants for good service, not obligatory. Round up taxis.
Official public transport app
Rome Termini, Rome -> Piazza Venezia, Rome
Find answers to the most common questions about traveling from Luxembourg to Rome by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Rome, this guide helps you travel smarter and with confidence.

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