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Travel Information
Compare bus and flight for Des Moines, IA to St. Louis, MO
Omio recommends booking the bus as it is the most popular option from Des Moines, IA to St. Louis, MO among Omio's users. If you are prioritising price take the bus with prices starting from $55. For those with little time consider booking a flight which can get you there in 2h 51m. The ticket price range depends on the travel mode: a bus costs an average of $55, and a flight costs an average of $173.
Distance: 273 miles (440 km)
Compare bus with
Most popular Bus | Flight | Driving |
|---|---|---|
$142 Average price Cheapest | $309 Average price | $69 Average price (fuel + tolls) |
10h 8m Average total duration 9h 38m Onboard + 30m Additional time* | 5h 51m Average total duration Fastest 2h 51m Onboard + 3h 0m Additional time* | 5h 28m Average total duration (door-to-door) |
 Most popular bus company |  Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Des Moines, IA to St. Louis, MO:
A bus is $168 (€135) less than a flight for this route with tickets for a flight from Des Moines, IA to St. Louis, MO costing on average $309 (€250).
Other travel options to St. Louis, MO take longer:
Bus takes on average 9h 38m.
Compare prices and tickets Des Moines, IA to St. Louis, MO by bus or flight
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Train from Des Moines, IA to St. Louis, MO
USAUSA
Take a train from Des Moines, IA to St. Louis, MO and enjoy the approximately 273 miles (440 km) long journey. Find schedules and pricing options for a convenient and affordable trip.
Distance 273 miles (440 km) |
High Season Oct - Dec |
Low Season Apr - Jun |
Busiest Day Sun |
Least Busy Day Sun |
FAQs: Trains from Des Moines, IA to St. Louis, MO
Find answers to the most common questions about traveling from Des Moines, IA to St. Louis, MO by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at St. Louis, MO, this guide helps you travel smarter and with confidence.
More options for your journey from Des Moines, IA to St. Louis, MO
Here are some other resources that might have the information you need
Most popular trains to and from St. Louis, MO and Des Moines, IA
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