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Travel Information
Compare bus and flight for Des Moines, IA to St. Louis, MO
Omio recommends booking the flight as it is the most popular option from Des Moines, IA to St. Louis, MO among Omio's users. If you are prioritising price take the bus with prices starting from €59. For those with little time consider booking a flight which can get you there in 2h 51m. The ticket price range depends on the travel mode: a bus costs an average of €59, and a flight costs an average of €68.
Distance: 273 miles (440 km)
Compare flight with
Most popular Flight | Bus |
|---|---|
€214 Average price | €94 Average price Cheapest |
5h 51m Average total duration Fastest 2h 51m Onboard + 3h 0m Additional time* | 14h 15m Average total duration 13h 45m Onboard + 30m Additional time* |
 Most popular airline |  Most popular bus company |
Direct Options | Direct Options |
Compare prices and tickets Des Moines, IA to St. Louis, MO by bus or flight
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Train from Des Moines, IA to St. Louis, MO
USAUSA
Take a train from Des Moines, IA to St. Louis, MO and enjoy the approximately 273 miles (440 km) long journey. Find schedules and pricing options for a convenient and affordable trip.
Distance 273 miles (440 km) |
FAQs: Trains from Des Moines, IA to St. Louis, MO
Find answers to the most common questions about traveling from Des Moines, IA to St. Louis, MO by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at St. Louis, MO, this guide helps you travel smarter and with confidence.
More options for your journey from Des Moines, IA to St. Louis, MO
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Most popular trains to and from St. Louis, MO and Des Moines, IA
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