Southampton to Brussels bus

Sun, Feb 22
+ Add return
FlixBus
Costa Verde
Alsa
BlaBlaCar Bus
Rede Expressos
1,000+ travel companies
FlixBus
Costa Verde
Alsa
BlaBlaCar Bus
Rede Expressos
1,000+ travel companies
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Compare prices and tickets Southampton to Brussels by flight

Compare flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

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Journey information

Overview: Bus from Southampton to Brussels

United KingdomUnited Kingdom
BelgiumBelgium
Icon of bus

Take a bus from Southampton to Brussels and enjoy the approximately 251 miles (404 km) long journey. Find schedules and pricing options for a convenient and affordable trip.

The earliest bus runs at 02:00, the last at 23:40.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $76 (€60)
Distance
251 miles (404 km)
Buses per day
2
First bus
02:00
Last bus
23:40
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $76 (€60)

FAQs: Bus from Southampton to Brussels

Find answers to the most common questions about traveling from Southampton to Brussels by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Brussels, this guide helps you travel smarter and with confidence.

FAQs
The earliest bus from Southampton to Brussels leaves at 2:00 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Southampton to Brussels leaves at 11:40 PM.
The cheapest month for a bus from Southampton to Brussels is August.
Yes, you can take a flight between Southampton and Brussels.
No, the bus from Southampton to Brussels has no accessibility options.
No, there are no bathrooms on board the bus from Southampton to Brussels.
Some of the most interesting sights to explore in Brussels are:
  • Grand Place, a UNESCO World Heritage site known for its opulent guildhalls and vibrant flower market
  • Atomium, an iconic structure and museum offering panoramic views of the city
  • Manneken Pis, a famous bronze statue symbolizing the irreverent spirit of Brussels
  • Royal Palace of Brussels, the official palace of the Belgian king with impressive architecture and gardens
  • Magritte Museum, dedicated to the works of surrealist artist René Magritte, featuring an extensive collection of his paintings and drawings.
The best things to do in Brussels include:
  • Explore the vibrant Marolles district, known for its eclectic mix of antique shops and street art
  • Enjoy a leisurely stroll through the picturesque Parc du Cinquantenaire, home to impressive arches and museums
  • Sample Belgian chocolates at one of the city's renowned chocolatiers
  • Discover the lively atmosphere of the Saint-Géry district, filled with trendy bars and cafes
  • Attend a performance at the historic La Monnaie opera house, showcasing world-class productions.
No, bikes are not allowed on board the bus from Southampton to Brussels.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
No, there is no food available to purchase on board the bus from Southampton to Brussels.
No, luggage for the bus from Southampton to Brussels needs to be booked in addition.
No, there are no additional luggage options for the bus from Southampton to Brussels.
Unfortunately, pets are not allowed on the bus from Southampton to Brussels.
No, there are no USB plugs on board the bus from Southampton to Brussels.
No, there is no WiFi on board the bus from Southampton to Brussels.

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