- Must visit
Musical Instruments Museum
Major museum in an Art Nouveau landmark with an outstanding collection of instruments from around the world and panoramic rooftop views.
No buses found
We are not able to find a bus between these two places.
The cheapest and fastest busesfrom Southampton to BrusselsShowing times and prices for Jul 09
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Southampton to Brussels bus with National Express
Travel Information
Compare bus and flight for Southampton to Brussels
Omio recommends booking the flight as it is the most popular option from Southampton to Brussels among Omio's users. If you are prioritising price take the bus with prices starting from $49. For those with little time consider booking a flight which can get you there in 1h 28m. The ticket price range depends on the travel mode: a bus costs an average of $49, and a flight costs an average of $78.
Distance: 251 miles (404 km)
Compare bus with
| Bus | Most popular Flight | Driving |
|---|---|---|
$62 Average price Cheapest | $138 Average price | $49 Average price (fuel + tolls) |
11h 40m Average total duration 11h 10m Onboard + 30m Additional time* | 4h 28m Average total duration Fastest 1h 28m Onboard + 3h 0m Additional time* | 5h 54m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options |
The cheapest way to travel from Southampton to Brussels is a bus with an average price of $62 (€51).
This is compared to other travel options from Southampton to Brussels:
A bus is $76 (€63) less than a flight for this route with tickets for a flight from Southampton to Brussels costing on average $138 (€113).
The fastest way to travel from Southampton to Brussels is by flight with an average journey time of 1h 28m.
Other travel options to Brussels take longer:
Bus takes on average 11h 10m.
It's helpful to compare your options as there are 2 ways to travel between Southampton and Brussels including taking a bus and flight.
We recommend using the flight as it is the most popular way to get from Southampton to Brussels among Omio's users.
Take the bus. On this route, it's both cheaper and quicker than driving.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
Southampton to Brussels Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator National Express | Departure Time 07:00AM | Arrival Time 06:30PM | Duration 11h30 | Departure days Thu | Cheapest price $68 |
Operator FlixBus | Departure Time 07:15AM | Arrival Time 06:30PM | Duration 11h15 | Departure days Thu | Cheapest price $49 |
Operator National Express | Departure Time 07:45AM | Arrival Time 06:30PM | Duration 10h45 | Departure days Sun | Cheapest price $68 |
Live departures
Southampton to Brussels bus times
The table below shows live departures for Southampton to Brussels buses for today, Thursday, July 9. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
 | 7:00 AM Southampton | 11h30 | 6:30 PM Brussels | 1 transfer | |
 | 7:15 AM Southampton | 11h15 | 6:30 PM Brussels | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Southampton to Brussels by bus or flight
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Southampton to Brussels buses with Omio?
National Express as well as FlixBus offer buses services from Southampton to Brussels.
Omio is an official ticket reseller for all your travel options from Southampton to Brussels.
Why book with Omio vs National Express?
- Compare with other providers: On Omio, you can not only buy tickets for National Express, but also compare tickets for the likes of FlixBus to find the best option for your trip from Southampton to Brussels.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare National Express with all available travel options, which are bus and flight to ensure you get the best deal for traveling from Southampton to Brussels.
Why book with Omio over Wanderu or Trainline?
- Compare with other providers: On Omio, you can also compare tickets for the likes of FlixBus to find the best option for your trip from Southampton to Brussels.
- Multiple modes of transport: Omio allows you to compare travel options including bus and flight to find the ideal travel option from Southampton to Brussels.
Journey information
Overview: Bus from Southampton to Brussels
United Kingdom
Belgium
Buses from Southampton to Brussels run on average 2 times per day, taking around 11h 10m. Cheap bus tickets for this journey start at $49 (€40) if you book in advance.
The earliest bus runs at 02:00, the last at 23:40. The fastest bus covers the 251 miles (404 km) distance in 10h 45m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 251 miles (404 km) |
Average bus duration 11h 10m |
Cheapest ticket price $49 (€40) |
Buses per day 2 |
Fastest bus 10h 45m |
First bus 2:00 AM |
Last bus 11:40 PM |
Cheapest Month Aug |
Cheapest Day Mon |
High Season Oct - Dec |
Low Season Jan - Mar |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Bus providers: National Express, FlixBus from Southampton to BrusselsYou can travel by bus between Southampton to Brussels with National Express, FlixBus for as low as $49 (€40). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
11h 15m
Cheapest Price
$49 (€40)
FlixBus frequency
1 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
National Express
About
National Express is the UK’s leading long-distance coach company, operating over 550 services per day and serving more than 900 destinations nationwide. It also runs frequent services to major UK airports — including Heathrow, Gatwick, Stansted, Luton, and Bristol — 24 hours a day. All National Express coaches are air-conditioned and offer free Wi-Fi and onboard entertainment. Most vehicles are equipped with seat belts and power outlets at every seat, allowing you to charge your phone or laptop during your journey. Ticket options include Restricted Fare, Standard Fare, and Fully Flexible Fare, with the latter providing maximum flexibility for cancellations or changes.
Luggage & cancellation policy
Average Duration
10h 45m
Cheapest Price
$68 (€56)
National Express frequency
1 a day
Luggage included
Two medium-sized suitcases up to 20kg each and one small piece of hand luggage.
Additional luggage
10€ per additional bag.
Cancellation Policy
You can cancel your ticket up to 24 hours before departure for a refund minus a cancellation fee. Changes can be up to 24 hours before departure for a fee.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Accessible toilets.
Bikes
Folding Bikes are allowed; non-folding bikes are not allowed.
Complete guide to Brussels
Things to do in Brussels
Discover the best of Brussels — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Brussels trip today.
- Must visit
Magritte Museum
Leading museum dedicated to René Magritte, presenting a large collection of surrealist works in the Royal Museums complex.
- Must visit
Royal Museums of Fine Arts of Belgium
Flagship fine arts museums covering Flemish masters, Belgian art, and major temporary exhibitions in central Brussels.
- Must visit
Galeries Royales Saint-Hubert
Elegant 19th-century covered arcade lined with historic shops and cafes, popular for architecture, strolling, and photos.
- Must visit
Mont des Arts Garden
Terraced garden and viewpoint with one of the most recognizable panoramas in central Brussels.
- Recommended
Place du Grand Sablon
Stylish square known for antiques, architecture, and an upscale yet distinctly Brussels atmosphere.
- Gluten-free
Moules-Frites
Mussels steamed with white wine, celery, and herbs, served with fries. It is one of Belgium’s most iconic comfort dishes and a staple in Brussels brasseries.
Carbonnade Flamande
A traditional Belgian beef and onion stew slowly cooked with dark Belgian beer, often slightly sweet-sour and served with fries or bread.
- Vegetarian
- Gluten-free
Stoemp
A rustic Brussels side dish of mashed potatoes mixed with vegetables such as carrots, leeks, or spinach, commonly served with sausage or meat dishes.
Comme Chez Soi Brussels
One of Brussels’ most famous fine dining institutions, celebrated for refined Belgian-French cuisine and elegant historic interiors.
Fin de Siècle Brussels
Popular traditional restaurant known for generous Belgian comfort food, beer-based dishes, and an informal, bustling atmosphere.
Chez Léon Brussels
Historic, long-running brasserie best known for moules-frites and classic Belgian dishes in a lively central setting.
Euro
Brussels is pricier than many Belgian cities. Hotels and dining add up, but transit and casual eats are manageable.
Average meal costs
- Budget
- EUR 10-18 for fries, kebabs, or simple lunch.
- Mid-range
- EUR 25-45 per person at a standard restaurant.
- Fine dining
- EUR 80+ per person at upscale restaurants.
- Coffee
- EUR 3-5 for a cappuccino or latte.
Tipping culture
Service is usually included. Tipping is not required, but rounding up or leaving 5-10% for great service is appreciated. Round up taxi fares; small tips are optional at cafes and bars.
STIB-MIVB
Get the appOfficial public transport app
Prices
- Single ticket
- 2.60 EUR
- Day pass
- 8.40 EUR
To the city center
Brussels South (Gare du Midi), Brussels -> Brussels-Central, Brussels
- Distance
- 2 km
- Travel time
- 5 min
- Contactless card payment is accepted directly on STIB-MIVB trams, buses, and metro via tap payment.
- A single STIB-MIVB ticket is valid for 60 min with transfers, but SNCB train travel between stations requires a separate rail ticket.
FAQs: Bus from Southampton to Brussels
Find answers to the most common questions about traveling from Southampton to Brussels by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Brussels, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Southampton to Brussels can start from as little as $49 (€40) when you book in advance. The average bus ticket price for Southampton to Brussels is $62 (€51) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Southampton to Brussels is 10h 45m to travel the 251 miles (404 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Southampton to Brussels leaves at 2:00 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Southampton to Brussels leaves at 11:40 PM.
There are 2 buses a day from Southampton to Brussels which require at least one change with National Express, FlixBus. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Southampton to Brussels, you can count on National Express, FlixBus for the best way to get you to Brussels. You can also check all possible bus companies who offer a service between Southampton and Brussels and compare the amenities they offer before buying a bus ticket.
A trip to Brussels from Southampton is worth doing but not as a day trip with a journey time of 10h 45m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Southampton to Brussels is August.
It's helpful to compare your options as there are 2 ways to travel between Southampton and Brussels including taking a bus and flight.
Yes, the following accessibility options are available when taking the bus from Southampton to Brussels:
- National Express
- Assistance
- Priority seating
- Accessible toilets.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Southampton to Brussels for bus company National Express, FlixBus.
Some of the most interesting sights to explore in Brussels are:
- Grand Place, a UNESCO World Heritage site known for its opulent guildhalls and vibrant flower market
- Atomium, an iconic structure and museum offering panoramic views of the city
- Manneken Pis, a famous bronze statue symbolizing the irreverent spirit of Brussels
- Royal Palace of Brussels, the official palace of the Belgian king with impressive architecture and gardens
- Magritte Museum, dedicated to the works of surrealist artist René Magritte, featuring an extensive collection of his paintings and drawings.
The best things to do in Brussels include:
- Explore the vibrant Marolles district, known for its eclectic mix of antique shops and street art
- Enjoy a leisurely stroll through the picturesque Parc du Cinquantenaire, home to impressive arches and museums
- Sample Belgian chocolates at one of the city's renowned chocolatiers
- Discover the lively atmosphere of the Saint-Géry district, filled with trendy bars and cafes
- Attend a performance at the historic La Monnaie opera house, showcasing world-class productions.
Whether you can cancel your bus ticket from Southampton to Brussels depends on the bus companies:
- National Express
- You can cancel your ticket up to 24 hours before departure for a refund minus a cancellation fee. Changes can be up to 24 hours before departure for a fee.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company National Express, FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Southampton to Brussels.
Yes, the following luggage options are included when booking a bus ticket from Southampton to Brussels:
- National Express
- Two medium-sized suitcases up to 20kg each and one small piece of hand luggage.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Southampton to Brussels:
- National Express
- 10€ per additional bag.
- FlixBus
- Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Southampton to Brussels. The following conditions apply:
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
You can reserve your seat on the bus from Southampton to Brussels with the following bus company: National Express, FlixBus
Yes, there are USB plugs on board the bus from Southampton to Brussels with the following bus company: National Express, FlixBus.
Yes, there is Wifi on board the bus from Southampton to Brussels with the following bus company: National Express, FlixBus.
Brussels is within the Schengen Area. Passport and visa requirements depend on your nationality. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the flight as it is the most popular way to get from Southampton to Brussels among Omio's users.
Currently, UK citizens do not need a visa for short stays (up to 90 days in a 180-day period) for tourism or business in the Schengen Area. However, the new ETIAS (European Travel Information and Authorisation System) is scheduled to launch in late 2026. Once active, this digital travel authorization will be a mandatory pre-travel requirement for all UK passport holders.
Belgium uses the euro (EUR) as its currency. Travelers generally find card payments widely accepted in cities, restaurants, and shops, though carrying some cash is advisable for small purchases or in rural areas.
In Brussels, travelers should be cautious of pickpocketing, especially in crowded areas like Grand Place, public transport, and popular tourist sites. Common scams include distraction techniques and fake petitions. It's advisable to stay vigilant, avoid displaying expensive items, and use official taxi services to ensure safety.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
Most popular bus connections from Southampton
More options for your journey from Southampton to Brussels
Here are some other resources that might have the information you need
Most popular buses to and from Brussels and Southampton
Most popular bus connections to Brussels
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