- Must visit
Royal Museums of Fine Arts of Belgium
Premier fine arts complex with Old Masters, Magritte, and modern collections, essential for understanding Belgian and European art.
Cheapest price on Oct 08
$48
Average ticket price on Oct 08
$57
Fastest journey on Oct 08
11 h 15 m
Average journey duration on Oct 08
11 h 23 m
Buses on Oct 08
2
Distance
404 km
The best way to find a cheap bus ticket from Southampton to Brussels is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Southampton to Brussels will cost around $57 if you buy it on the day, but the cheapest tickets can be found for only $48.
It's difficult to get from Southampton to Brussels without transferring at least once.




Take a bus from Southampton to Brussels and enjoy the approximately 251 miles (404 km) long journey. Find schedules and pricing options for a convenient and affordable trip.
The earliest bus runs at 02:00, the last at 23:40.
Distance 251 miles (404 km) |
First bus 2:00 AM |
Last bus 11:40 PM |
High Season Oct - Dec |
Low Season Jan - Mar |
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator National Express | Departure Time 07:00AM | Arrival Time 06:30PM | Duration 11h30 | Departure days Thu | Cheapest price $67 |
Operator FlixBus | Departure Time 07:15AM | Arrival Time 06:30PM | Duration 11h15 | Departure days Thu | Cheapest price $48 |
Operator National Express | Departure Time 07:45AM | Arrival Time 06:30PM | Duration 10h45 | Departure days Sun | Cheapest price $67 |
The table below shows live departures for Southampton to Brussels buses for tomorrow, Thursday, October 8. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 7:00 AM Southampton | 11h30 | 6:30 PM Brussels | 1 transfer | |
![]() | 7:15 AM Southampton | 11h15 | 6:30 PM Brussels | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Discover the best of Brussels — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Brussels trip today.
Premier fine arts complex with Old Masters, Magritte, and modern collections, essential for understanding Belgian and European art.
Dedicated to surrealist René Magritte, this popular museum presents major works and context for one of Belgium’s most celebrated artists.
Leading comic art museum in a Horta-designed building, highlighting Tintin, the Smurfs, and Belgium’s influential comics culture.
Grand square at Brussels’ heart, lined with ornate guildhalls and lively events, perfect for first-time visitors and evening atmosphere.
Large urban park with the triumphal arch, museums, and wide lawns, excellent for walking, picnics, and classic city photographs.
Popular hilltop viewpoint and garden terrace with one of the best panoramas over central Brussels, especially at sunset.
Mussels steamed with white wine, celery and onion, often served with fries. A Brussels brasserie classic, especially popular in mussel season.
Double-fried potato fries, traditionally served in paper cones with sauces. They are a point of national pride and central to everyday Belgian street food.
A rich beef and onion stew braised with Belgian dark beer. It is a beloved comfort dish found in traditional Brussels restaurants.
Two-Michelin-star restaurant by chef Karen Torosyan, celebrated for pâté en croûte and inventive fine dining in an intimate setting.
Elegant Belle Époque brasserie serving refined Belgian classics, seafood and game in a grand old-world dining room.
Famous casual stop for Brussels waffles with many toppings. Popular, fast-moving and central for a classic sweet local treat.
Moderate for Western Europe: hotels can be pricey, but dining and transit are manageable for most tourists.
Service is usually included. Round up or leave 5-10% for great restaurant service; round up taxi fares; small change is fine in cafes.
Official public transport app
Brussels South (Gare du Midi) -> Brussels Central Station, Brussels
Find answers to the most common questions about traveling from Southampton to Brussels by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Brussels, this guide helps you travel smarter and with confidence.

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