- Must visit
Science and Industry Museum
Leading museum of science, industry, transport, and computing on a historic railway site. Essential for understanding Manchester's global impact.
Cheapest price
€31
Average price
€40
Fastest journey
6 h 55 m
Average duration
7 h 16 m
Buses per day
12
Distance
292 km
The best way to find a cheap bus ticket from Southampton to Manchester is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Southampton to Manchester will cost around €40 if you buy it on the day, but the cheapest tickets can be found for only €31.
It's difficult to get from Southampton to Manchester without transferring at least once.
NX032 · NX540
NX032 · NX424
NX032 · NX540
NX160 · NX120
NX032 · NX421
NX160 · NX120
NX160 · NX541
NX160 · NX541
FlixBus · FlixBus
FlixBus · FlixBusBuses from Southampton to Manchester run on average 14 times per day, taking around 6h 30m. Cheap bus tickets for this journey start at €17 if you book in advance.
The earliest bus runs at 00:05, the last at 23:55. The fastest bus covers the 181 miles (292 km) distance in 7h 10m.
Distance 181 miles (292 km) |
Average bus duration 6h 30m |
Cheapest ticket price €17 |
Buses per day 14 |
Fastest bus 7h 10m |
First bus 12:05 AM |
Last bus 11:55 PM |
Cheapest Month Feb |
Cheapest Day Wed |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Fri |
Least Busy Day Sun |
Best time to book 7 days |
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 04:05AM | Arrival Time 11:50AM | Duration 7h45 | Departure days Mon, Sun | Cheapest price €28 |
Operator National Express | Departure Time 04:15AM | Arrival Time 12:10PM | Duration 7h55 | Departure days Everyday | Cheapest price €31 |
Operator FlixBus | Departure Time 04:20AM | Arrival Time 11:50AM | Duration 7h30 | Departure days Everyday | Cheapest price €28 |
Operator National Express | Departure Time 05:05AM | Arrival Time 01:50PM | Duration 8h45 | Departure days Mon, Fri | Cheapest price €30 |
Operator National Express | Departure Time 05:25AM | Arrival Time 01:50PM | Duration 8h25 | Departure days Sat, Sun | Cheapest price €45 |
Operator National Express | Departure Time 05:35AM | Arrival Time 02:40PM | Duration 9h05 | Departure days Tue, Wed, Thu | Cheapest price €27 |
Operator FlixBus | Departure Time 06:05AM | Arrival Time 01:50PM | Duration 7h45 | Departure days Mon, Sun | Cheapest price €28 |
Operator FlixBus | Departure Time 06:25AM | Arrival Time 01:50PM | Duration 7h25 | Departure days Everyday | Cheapest price €28 |
Operator National Express | Departure Time 08:55AM | Arrival Time 04:05PM | Duration 7h10 | Departure days Mon, Tue, Wed, Thu, Fri | Cheapest price €28 |
Operator National Express | Departure Time 09:00AM | Arrival Time 04:05PM | Duration 7h05 | Departure days Sat, Sun | Cheapest price €30 |
Operator National Express | Departure Time 09:15AM | Arrival Time 06:10PM | Duration 8h55 | Departure days Mon, Fri, Sat, Sun | Cheapest price €21 |
Operator FlixBus | Departure Time 10:45AM | Arrival Time 07:30PM | Duration 8h45 | Departure days Mon, Sun | Cheapest price €29 |
Operator FlixBus | Departure Time 11:05AM | Arrival Time 07:30PM | Duration 8h25 | Departure days Everyday | Cheapest price €29 |
Operator National Express | Departure Time 11:55AM | Arrival Time 07:40PM | Duration 7h45 | Departure days Fri | Cheapest price €61 |
Operator National Express | Departure Time 12:10PM | Arrival Time 07:30PM | Duration 7h20 | Departure days Mon, Tue, Wed, Thu, Sat, Sun | Cheapest price €26 |
Operator National Express | Departure Time 12:15PM | Arrival Time 10:10PM | Duration 9h55 | Departure days Everyday | Cheapest price €20 |
Operator National Express | Departure Time 01:15PM | Arrival Time 10:10PM | Duration 8h55 | Departure days Mon | Cheapest price €16 |
Operator National Express | Departure Time 04:00PM | Arrival Time 10:55PM | Duration 6h55 | Departure days Everyday | Cheapest price €28 |
Operator National Express | Departure Time 04:30PM | Arrival Time 01:40AM | Duration 9h10 | Departure days Tue, Wed, Thu | Cheapest price €20 |
Operator National Express | Departure Time 05:20PM | Arrival Time 02:15AM | Duration 8h55 | Departure days Fri | Cheapest price €22 |
Operator National Express | Departure Time 05:30PM | Arrival Time 02:15AM | Duration 8h45 | Departure days Mon, Sat, Sun | Cheapest price €22 |
Operator National Express | Departure Time 06:30PM | Arrival Time 06:05AM | Duration 11h35 | Departure days Tue, Wed, Thu | Cheapest price €31 |
Operator National Express | Departure Time 07:00PM | Arrival Time 06:05AM | Duration 11h05 | Departure days Mon, Fri, Sat, Sun | Cheapest price €30 |
Operator National Express | Departure Time 08:30PM | Arrival Time 07:35AM | Duration 11h05 | Departure days Everyday | Cheapest price €30 |
The table below shows live departures for Southampton to Manchester buses for today, Tuesday, August 4. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
NX160 · NX120 | 4:00 PM Southampton, Coach Station | 6h55 | 10:55 PM Manchester, Coach Station | 1 transfer | |
NX032 · NX541 | 4:30 PM Southampton, Coach Station | 9h10 | 1:40 AM Manchester, Coach Station | 1 transfer | |
NX032 · NX424 | 6:30 PM Southampton, Coach Station | 11h35 | 6:05 AM Manchester, Coach Station | 1 transfer | |
NX032 · NX421 | 8:30 PM Southampton, Coach Station | 11h05 | 7:35 AM Manchester, Coach Station | 1 transfer | |
| Wednesday, August 5 | |||||
NX032 · NX540 | 4:15 AM Southampton, Coach Station | 7h55 | 12:10 PM Manchester, Coach Station | 1 transfer | |
FlixBus · FlixBus | 4:20 AM Southampton, Burgess Rd / Broadlands Rd (Southampton University) | 7h30 | 11:50 AM Manchester, Shudehill Interchange | 1 transfer | |
NX032 · NX540 | 5:35 AM Southampton, Coach Station | 9h05 | 2:40 PM Manchester, Coach Station | 1 transfer | |
FlixBus · FlixBus | 6:25 AM Southampton, Burgess Rd / Broadlands Rd (Southampton University) | 7h25 | 1:50 PM Manchester, Shudehill Interchange | 1 transfer | |
NX160 · NX541 | 8:55 AM Southampton, Coach Station | 7h10 | 4:05 PM Manchester, Coach Station | 1 transfer | |
FlixBus · FlixBus | 11:05 AM Southampton, Burgess Rd / Broadlands Rd (Southampton University) | 8h25 | 7:30 PM Manchester, Shudehill Interchange | 1 transfer | |
NX160 · NX541 | 12:10 PM Southampton, Coach Station | 7h20 | 7:30 PM Manchester, Coach Station | 1 transfer | |
NX032 · NX540 | 12:15 PM Southampton, Coach Station | 9h55 | 10:10 PM Manchester, Coach Station | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Discover the best of Manchester — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Manchester trip today.
Leading museum of science, industry, transport, and computing on a historic railway site. Essential for understanding Manchester's global impact.
Major art museum with Pre-Raphaelite works, design, and changing exhibitions. A central cultural stop with broad appeal.
The University of Manchester museum spans dinosaurs, Egypt, nature, and anthropology. Recently renewed and excellent for varied interests.
Historic canal-side district with Roman remains, warehouses, and walkable towpaths. One of Manchester's most atmospheric urban areas.
Central square framed by grand civic buildings, museums, and monuments. A classic starting point for exploring the city centre.
Creative quarter of street art, music history, indie shops, and nightlife. It is one of Manchester's most characterful neighborhoods.
A flaky pastry pie filled with spiced potatoes, onion and often chickpeas. Created by Manchester’s South Asian community and now a city staple.
A comforting Northern pudding of suet pastry filled with beef and onion, traditionally steamed and served with gravy. Common in Greater Manchester pubs.
Manchester’s classic order of battered fish with chips, often served with mushy peas and curry sauce. A long-standing local takeaway favourite.
Iconic market bakery and café known for Manchester tarts, Eccles cakes and hearty lunches. Casual, busy and deeply rooted in local food culture.
Refined modern British fine dining in a restored townhouse. Known for tasting menus, polished service and one of Manchester’s top culinary reputations.
Lively Indian restaurant famous for bold curries, grills and chaat. A long-established Rusholme favourite with a casual, energetic atmosphere.
Moderate for the UK: hotels often cost less than London, while dining and transit are manageable for tourists with many mid-range options.
Service may be included. If not, 10-12.5% in restaurants is common for good service. Round up or add a little for taxis. Cafe tipping is optional.
Find answers to the most common questions about traveling from Southampton to Manchester by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Manchester, this guide helps you travel smarter and with confidence.

Most Southampton to Manchester buses use the Southampton, Coach Station to Manchester, Coach Station station pair, with some services arriving at Manchester, Shudehill Interchange. Use this guide to compare Southampton and Manchester bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Southampton, Coach Station has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Café Express (in the station), Sandwich Bar (in the station).
Free Wi-Fi. ATMs are located near the entrance for cash withdrawals.
Ticket office support is available at Southampton, Coach Station.
Available at Southampton, Coach Station: Parking, Taxis, WC.
Accessibility facilities are available at Southampton, Coach Station: Elevators, ramps.
Manchester, Coach Station has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Café at the Station (in the station), Fast Food Express (in the station).
Free Wi-Fi. ATMs are located within the station for cash withdrawals.
Ticket office support is available at Manchester, Coach Station.
Available at Manchester, Coach Station: Parking, Taxis, WC.
Accessibility facilities are available at Manchester, Coach Station: Ramps, assistance.
Manchester, Shudehill Interchange has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, and Ticket Office.
Free Wi-Fi. ATMs are located near the main entrance.
Ticket office support is available at Manchester, Shudehill Interchange.
Available at Manchester, Shudehill Interchange: Parking, Taxis, WC.
Accessibility facilities are available at Manchester, Shudehill Interchange: Elevators, ramps.
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