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The cheapest and fastest buses from Southampton to Manchester
Showing times and prices for Mar 22
Cheapest price
$63
Average price
$72
Fastest journey
7 h 10 m
Average duration
7 h 37 m
Buses per day
16
Distance
292 km
Cheap tickets
The best way to find a cheap bus ticket from Southampton to Manchester is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Southampton to Manchester will cost around $72 if you buy it on the day, but the cheapest tickets can be found for only $63.
Fast buses
It's difficult to get from Southampton to Manchester without transferring at least once.
NX032 · NX42108:30PM11h05
Southampton, Coach Station07:35AMManchester, Coach Station
$631One-way
1 transfer
NX032 · NX54004:15AM8h05
Southampton, Coach Station12:20PMManchester, Coach Station
$651One-way
1 transfer
FlixBus · FlixBus05:00PM10h30
Southampton Central (SOU)03:30AMManchester, Shudehill Interchange
$701One-way
1 transfer
FlixBus · FlixBus05:15PM10h15
Southampton, Burgess Rd / Broadlands Rd (Southampton University)03:30AMManchester, Shudehill Interchange
$701One-way
1 transfer
NX032 · NX54005:25AM8h45
Southampton, Coach Station02:10PMManchester, Coach Station
$701One-way
1 transfer
NX160 · NX12004:00PM7h10
Southampton, Coach Station11:10PMManchester, Coach Station
$761One-way
1 transfer
NX160 · NX12012:10PM7h10
Southampton, Coach Station07:20PMManchester, Coach Station
$781One-way
1 transfer
NX160 · NX12009:00AM7h25
Southampton, Coach Station04:25PMManchester, Coach Station
$731One-way
1 transfer
NX032 · NX54004:15AM8h05
Southampton, Coach Station12:20PMManchester, Coach Station
$651One-way
1 transfer
NX032 · NX54005:30PM8h15
Southampton, Coach Station01:45AMManchester, Coach Station
$711One-way
1 transfer
Travel Information
Compare train, bus, and flight for Southampton to Manchester
Omio recommends booking the bus as it is the most popular option from Southampton to Manchester among Omio's users. If you are prioritising price take the bus with prices starting from $18. For those with little time consider booking a flight which can get you there in 1h 8m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.3kg. The ticket price range depends on the travel mode: a bus costs an average of $18, and a flight costs an average of $74.
Distance: 181 miles (292 km)
Compare bus with
Most popular Bus | Train | Flight |
|---|---|---|
$42 Average price Cheapest | $110 Average price | $141 Average price |
6h 50m Average total duration 6h 20m Onboard + 30m Additional time* | 4h 36m Average total duration 4h 6m Onboard + 30m Additional time* | 4h 8m Average total duration Fastest 1h 8m Onboard + 3h 0m Additional time* |
0.3 - 0.7kg CO2 emissions | 0.1 - 0.3kg CO2 emissions Lowest | - CO2 emissions |
 Most popular bus company |  Most popular train company |  Most popular airline |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Southampton to Manchester Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator National Express | Departure Time 04:15AM | Arrival Time 12:20PM | Duration 8h05 | Departure days Sat, Sun | Cheapest price $65 |
Operator National Express | Departure Time 05:25AM | Arrival Time 02:10PM | Duration 8h45 | Departure days Sat, Sun | Cheapest price $51 |
Operator National Express | Departure Time 06:45AM | Arrival Time 03:50PM | Duration 9h05 | Departure days Sat, Sun | Cheapest price $53 |
Operator National Express | Departure Time 09:00AM | Arrival Time 04:25PM | Duration 7h25 | Departure days Sat, Sun | Cheapest price $73 |
Operator National Express | Departure Time 09:15AM | Arrival Time 06:05PM | Duration 8h50 | Departure days Sun | Cheapest price $74 |
Operator FlixBus | Departure Time 10:45AM | Arrival Time 07:30PM | Duration 8h45 | Departure days Sat, Sun | Cheapest price $73 |
Operator FlixBus | Departure Time 11:00AM | Arrival Time 07:30PM | Duration 8h30 | Departure days Sat, Sun | Cheapest price $73 |
Operator National Express | Departure Time 12:10PM | Arrival Time 07:20PM | Duration 7h10 | Departure days Sat, Sun | Cheapest price $67 |
Operator National Express | Departure Time 12:15PM | Arrival Time 09:00PM | Duration 8h45 | Departure days Sat, Sun | Cheapest price $50 |
Operator National Express | Departure Time 01:15PM | Arrival Time 09:45PM | Duration 8h30 | Departure days Sat, Sun | Cheapest price $53 |
Operator National Express | Departure Time 04:00PM | Arrival Time 11:10PM | Duration 7h10 | Departure days Sat, Sun | Cheapest price $69 |
Operator FlixBus | Departure Time 05:00PM | Arrival Time 03:30AM | Duration 10h30 | Departure days Sat, Sun | Cheapest price $60 |
Operator FlixBus | Departure Time 05:15PM | Arrival Time 03:30AM | Duration 10h15 | Departure days Sat, Sun | Cheapest price $60 |
Operator National Express | Departure Time 05:30PM | Arrival Time 01:45AM | Duration 8h15 | Departure days Sat, Sun | Cheapest price $51 |
Operator National Express | Departure Time 07:00PM | Arrival Time 06:05AM | Duration 11h05 | Departure days Sat, Sun | Cheapest price $58 |
Operator National Express | Departure Time 08:30PM | Arrival Time 07:35AM | Duration 11h05 | Departure days Sat, Sun | Cheapest price $63 |
Live departures
Southampton to Manchester bus times
The table below shows live departures for Southampton to Manchester buses for tomorrow, Saturday, March 21. You can also manually refresh the results below to see updated bus journeys.
Last updated at 7:08 PM
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| NX032 · NX540 | Delayed 11:20 AM 4:15 AMSouthampton, Coach Station | 8h05 | 12:20 PM Manchester, Coach Station | 1 transfer | |
| NX032 · NX540 | Delayed 11:20 AM 5:25 AMSouthampton, Coach Station | 8h45 | 2:10 PM Manchester, Coach Station | 1 transfer | |
| NX032 · NX540 | Delayed 11:20 AM 6:45 AMSouthampton, Coach Station | 9h05 | 3:50 PM Manchester, Coach Station | 1 transfer | |
| NX160 · NX120 | On time 9:00 AM Southampton, Coach Station | 7h25 | 4:25 PM Manchester, Coach Station | 1 transfer | |
| NX032 · NX540 | Delayed 11:20 AM 9:15 AMSouthampton, Coach Station | 8h50 | 6:05 PM Manchester, Coach Station | 1 transfer | |
| FlixBus · FlixBus | 10:45 AM Southampton Central (SOU) | 8h45 | 7:30 PM Manchester, Shudehill Interchange | 1 transfer | |
| FlixBus · FlixBus | 11:00 AM Southampton, Burgess Rd / Broadlands Rd (Southampton University) | 8h30 | 7:30 PM Manchester, Shudehill Interchange | 1 transfer | |
| NX160 · NX120 | On time 12:10 PM Southampton, Coach Station | 7h10 | 7:20 PM Manchester, Coach Station | 1 transfer | |
| NX032 · NX540 | On time 12:15 PM Southampton, Coach Station | 8h45 | 9:00 PM Manchester, Coach Station | 1 transfer | |
| NX032 · NX540 | On time 1:15 PM Southampton, Coach Station | 8h30 | 9:45 PM Manchester, Coach Station | 1 transfer | |
| NX160 · NX120 | On time 4:00 PM Southampton, Coach Station | 7h10 | 11:10 PM Manchester, Coach Station | 1 transfer | |
| FlixBus · FlixBus | 5:00 PM Southampton Central (SOU) | 10h30 | 3:30 AM Manchester, Shudehill Interchange | 1 transfer | |
| FlixBus · FlixBus | 5:15 PM Southampton, Burgess Rd / Broadlands Rd (Southampton University) | 10h15 | 3:30 AM Manchester, Shudehill Interchange | 1 transfer | |
| NX032 · NX540 | On time 5:30 PM Southampton, Coach Station | 8h15 | 1:45 AM Manchester, Coach Station | 1 transfer | |
| NX032 · NX424 | On time 7:00 PM Southampton, Coach Station | 11h05 | 6:05 AM Manchester, Coach Station | 1 transfer | |
| NX032 · NX421 | On time 8:30 PM Southampton, Coach Station | 11h05 | 7:35 AM Manchester, Coach Station | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Southampton to Manchester by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Mar 22
Mar 22
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Mar 28
Mar 28
Why should you book Southampton to Manchester buses with Omio?
Megabus as well as National Express offer buses services from Southampton to Manchester.
Omio is an official ticket reseller for all your travel options from Southampton to Manchester.
Why book with Omio vs Megabus?
- Compare with other providers: On Omio, you can not only buy tickets for Megabus, but also compare tickets for the likes of National Express to find the best option for your trip from Southampton to Manchester.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Megabus with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Southampton to Manchester.
Why book with Omio over Wanderu?
- Compare with other providers: On Omio, you can also compare tickets for the likes of National Express to find the best option for your trip from Southampton to Manchester.
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Southampton to Manchester.
Journey information
Overview: Bus from Southampton to Manchester
United KingdomUnited Kingdom
Buses from Southampton to Manchester run on average 13 times per day, taking around 6h 20m. Cheap bus tickets for this journey start at $18 (€15) if you book in advance.
The earliest bus runs at 00:05, the last at 23:55. The fastest bus covers the 181 miles (292 km) distance in 7h 10m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 181 miles (292 km) |
Average bus duration 6h 20m |
Cheapest ticket price $18 (€15) |
Buses per day 13 |
Fastest bus 7h 10m |
First bus 00:05 |
Last bus 23:55 |
Cheapest month Mar |
Cheapest day Mon |
High season Jul - Sep |
Low season Jan - Mar |
Busiest day Fri |
Least busy day Tue |
Best day to book ahead 7 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Bus providers: Megabus, National Express from Southampton to ManchesterYou can travel by bus between Southampton to Manchester with Megabus, National Express for as low as $18 (€15). When you search for schedules and tickets, Omio will show you the best journey
Megabus
About
Megabus is a low-cost intercity bus service operating across the United States, Canada, and the United Kingdom. Known for its affordable fares, including promotional $1 tickets, Megabus offers routes connecting over 500 cities and university campuses in North America. The company provides amenities such as air conditioning, power outlets, free Wi-Fi, and onboard restrooms, with many routes utilizing double-decker buses for scenic views. Megabus aims to provide safe, convenient, and affordable express bus travel.
Luggage & cancellation policy
Average Duration
5h 55m
Cheapest Price
$58 (€47)
Megabus frequency
5 a day
Luggage included
One piece of luggage is included per passenger reservation. For guidance, a piece of luggage must not exceed 62 inches (length + width + height) and should not weigh more than 50 pounds (23kg).
Additional luggage
Additional luggage can be purchased by buying an additional travel ticket in advance or by adding up to two additional pieces when booking for a fee.
Cancellation Policy
Megabus reservations cannot be canceled or refunded, but they can be traded in for another journey up to 3 hours before your original scheduled departure for a fee.
Refund
If Megabus fails to provide on-time reliable service for reasons wholly within their control, refunds or alternative travel arrangements may be offered.
Pregnant on board
Being pregnant on board is allowed, but no specific details or restrictions are provided.
Unaccompagned minor
Unaccompanied minors under the age of 17 are not permitted to travel on Megabus.
Amenities on board the bus
Wifi
Food sold onboard
Cold food and drinks, as well as hot drinks with a lid, are allowed on board, but hot food is not.
Seat reservation
Reserved seats can be purchased for an additional fee, starting from £2.
Toilets
USB plugs
Accessibility
Megabus is ADA-compliant and provides assistance to customers with disabilities, including those using wheelchairs or mobility scooters, and those with service animals.
Entertaiment on board
National Express
About
National Express is the UK’s leading long-distance coach company, operating over 550 services per day and serving more than 900 destinations nationwide. It also runs frequent services to major UK airports — including Heathrow, Gatwick, Stansted, Luton, and Bristol — 24 hours a day. All National Express coaches are air-conditioned and offer free Wi-Fi and onboard entertainment. Most vehicles are equipped with seat belts and power outlets at every seat, allowing you to charge your phone or laptop during your journey. Ticket options include Restricted Fare, Standard Fare, and Fully Flexible Fare, with the latter providing maximum flexibility for cancellations or changes.
Luggage & cancellation policy
Average Duration
7h 10m
Cheapest Price
$18 (€15)
Luggage included
Two medium-sized suitcases up to 20kg each and one small piece of hand luggage.
Additional luggage
10€ per additional bag.
Cancellation Policy
You can cancel your ticket up to 24 hours before departure for a refund minus a cancellation fee. Changes can be up to 24 hours before departure for a fee.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Accessible toilets.
FAQs: Bus from Southampton to Manchester
Find answers to the most common questions about traveling from Southampton to Manchester by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Manchester, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Southampton to Manchester can start from as little as $18 (€15) when you book in advance. The average bus ticket price for Southampton to Manchester is $42 (€34) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Southampton to Manchester is 7h 10m to travel the 181 miles (292 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Southampton to Manchester leaves at 12:05 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Southampton to Manchester leaves at 11:55 PM.
There are 13 buses a day from Southampton to Manchester which require at least one change with Megabus, National Express. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Southampton to Manchester, you can count on Megabus, National Express for the best way to get you to Manchester. You can also check all possible bus companies who offer a service between Southampton and Manchester and compare the amenities they offer before buying a bus ticket.
When departing from Southampton , you have various bus station options to start your journey from including Southampton, Coach Station, Southampton, Burgess Rd / Broadlands Rd (Southampton University), Southampton, University . When arriving in Manchester , you can end your journey in bus stations like Manchester, Coach Station, Manchester, Shudehill Interchange, Manchester, Princess Road / Moss Lane East, Manchester, Airport .Passengers board the bus most frequently from Southampton, Coach Station, which is located around 0 away from the city centre, and they get off the bus at Manchester, Coach Station, located 0 away from the city centre.
A trip to Manchester from Southampton is worth doing but not as a day trip with a journey time of 7h 10m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Southampton to Manchester is March.
It's helpful to compare your options as there are 3 ways to travel between Southampton and Manchester including taking a train, bus, and flight.
Yes, the following accessibility options are available when taking the bus from Southampton to Manchester:
- Megabus
- Megabus is ADA-compliant and provides assistance to customers with disabilities, including those using wheelchairs or mobility scooters, and those with service animals.
- National Express
- Assistance
- Priority seating
- Accessible toilets.
Yes, there are bathrooms on board the bus from Southampton to Manchester for bus company Megabus, National Express.
Some of the most interesting sights to explore in Manchester are:
- Manchester Art Gallery, a public art museum housing an extensive collection of fine art and decorative pieces
- Science and Industry Museum, an interactive museum exploring Manchester's industrial heritage and scientific achievements
- Manchester Cathedral, a historic Gothic-style cathedral known for its stunning architecture and serene atmosphere
- The John Rylands Library, a neo-Gothic library with an impressive collection of rare books and manuscripts
- Castlefield, a historic area with Roman ruins and picturesque canals, perfect for a leisurely stroll.
The best things to do in Manchester include:
- Old Trafford, the iconic football stadium and home to Manchester United, offering tours and a museum dedicated to the club's history
- The Northern Quarter, a vibrant district known for its independent shops, cafes, and street art
- Visit the Manchester Opera House for a captivating performance
- Explore the vibrant nightlife at Deansgate Locks, a popular area with bars and clubs
- Enjoy a relaxing day at Heaton Park, one of the largest municipal parks in Europe, offering beautiful landscapes and recreational activities.
Whether you can cancel your bus ticket from Southampton to Manchester depends on the bus companies:
- Megabus
- Megabus reservations cannot be canceled or refunded, but they can be traded in for another journey up to 3 hours before your original scheduled departure for a fee.
- National Express
- You can cancel your ticket up to 24 hours before departure for a refund minus a cancellation fee. Changes can be up to 24 hours before departure for a fee.
Yes, bikes are allowed on board the bus with bus company National Express.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Southampton to Manchester.
Yes, the following luggage options are included when booking a bus ticket from Southampton to Manchester:
- Megabus
- One piece of luggage is included per passenger reservation. For guidance, a piece of luggage must not exceed 62 inches (length + width + height) and should not weigh more than 50 pounds (23kg).
- National Express
- Two medium-sized suitcases up to 20kg each and one small piece of hand luggage.
Yes, the following additional luggage options are available when booking a bus ticket from Southampton to Manchester:
- Megabus
- Additional luggage can be purchased by buying an additional travel ticket in advance or by adding up to two additional pieces when booking for a fee.
- National Express
- 10€ per additional bag.
Unfortunately, pets are not allowed on the bus from Southampton to Manchester.
You can reserve your seat on the bus from Southampton to Manchester with the following bus company: Megabus, National Express
Yes, there are USB plugs on board the bus from Southampton to Manchester with the following bus company: Megabus, National Express.
Yes, there is Wifi on board the bus from Southampton to Manchester with the following bus company: Megabus, National Express.
popular bus stations
Popular bus stations from Southampton to Manchester
Southampton
Manchester
The major bus station for departures in Southampton is Southampton, Coach Station. Find all the information you need to know about services, amenities and connections at Southampton, Coach Station for your trip from Southampton to Manchester.
Amenities at bus station
Wifi
Parking
Dining
ATM
Taxis
Accessibility
WC
Ticket Officeinformation
Ticket Office Hours
- 06:00-22:00
Car connection
Harbour ParadeWifi
- Free Wi-Fi
Dining
- Café Express (in the station)
- Sandwich Bar (in the station).
Taxis
- Available outside the station.
Accessibility
- Elevators, ramps
WC
- Available near the entrance.
Public transit options for Southampton, Coach Station
- Bus: U1, U2, U6, X4 Train: South Western Railway
Southampton, Burgess Rd (Library)
information
Southampton, University
information
The major bus station for arrivals in Manchester is Manchester, Coach Station. Find all the information you need to know about services, amenities and connections at Manchester, Coach Station for your trip to Manchester from Southampton.
Manchester, Coach Station
Amenities at bus station
WifiParkingDiningATMTaxisAccessibilityWCTicket Officeinformation
Ticket Office Hours
- 06:00-22:00
Car connection
Chorlton StreetWifi
- Free Wi-Fi
Dining
- Café at the Station (in the station)
- Fast Food Express (in the station).
Taxis
- Available outside the main entrance.
Accessibility
- Ramps, assistance
WC
- Available in the station.
Public transit options for Manchester, Coach Station
- Bus: 50, 192, 201, 203, 205, 219, 255, 256 Train: Manchester Piccadilly Metro: Piccadilly Gardens
Manchester, Shudehill Interchange
Amenities at bus station
WifiParkingATMTaxisAccessibilityWCTicket Officeinformation
Ticket Office Hours
- 05:00-23:30
Car connection
ShudehillWifi
- Free Wi-Fi
Taxis
- Available outside the interchange.
Accessibility
- Elevators, ramps
WC
- Available in the station.
Public transit options for Manchester, Shudehill Interchange
- Bus: 42, 43, 135 Tram: Metrolink
Manchester, Princess Road / Moss Lane East
information
Most popular bus connections from Southampton
More options for your journey from Southampton to Manchester
Here are some other resources that might have the information you need
Most popular buses to and from Manchester and Southampton
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