- Must visit
Musical Instruments Museum
Major museum in an Art Nouveau landmark with an outstanding collection of instruments from around the world and panoramic rooftop views.
Omio recommends booking the flight as it is the most popular option from Southampton to Brussels among Omio's users. If you are prioritising price take the bus with prices starting from $49. For those with little time consider booking a flight which can get you there in 1h 28m. The ticket price range depends on the travel mode: a bus costs an average of $49, and a flight costs an average of $78.
Distance: 251 miles (404 km)
Most popular Flight | Bus | Driving |
|---|---|---|
$138 Average price | $62 Average price Cheapest | $50 Average price (fuel + tolls) |
4h 28m Average total duration Fastest 1h 28m Onboard + 3h 0m Additional time* | 11h 40m Average total duration 11h 10m Onboard + 30m Additional time* | 5h 54m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Southampton to Brussels:
A bus is $76 (€63) less than a flight for this route with tickets for a flight from Southampton to Brussels costing on average $138 (€113).
Other travel options to Brussels take longer:
Bus takes on average 11h 10m.
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Take a train from Southampton to Brussels and enjoy the approximately 251 miles (404 km) long journey. Find schedules and pricing options for a convenient and affordable trip.
The earliest train runs at 05:53, the last at 17:45.
Distance 251 miles (404 km) |
First train 5:53 AM |
Last train 5:45 PM |
High Season Oct - Dec |
Low Season Jan - Mar |
Discover the best of Brussels — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Brussels trip today.
Major museum in an Art Nouveau landmark with an outstanding collection of instruments from around the world and panoramic rooftop views.
Leading museum dedicated to René Magritte, presenting a large collection of surrealist works in the Royal Museums complex.
Flagship fine arts museums covering Flemish masters, Belgian art, and major temporary exhibitions in central Brussels.
Elegant 19th-century covered arcade lined with historic shops and cafes, popular for architecture, strolling, and photos.
Terraced garden and viewpoint with one of the most recognizable panoramas in central Brussels.
Stylish square known for antiques, architecture, and an upscale yet distinctly Brussels atmosphere.
Mussels steamed with white wine, celery, and herbs, served with fries. It is one of Belgium’s most iconic comfort dishes and a staple in Brussels brasseries.
A traditional Belgian beef and onion stew slowly cooked with dark Belgian beer, often slightly sweet-sour and served with fries or bread.
A rustic Brussels side dish of mashed potatoes mixed with vegetables such as carrots, leeks, or spinach, commonly served with sausage or meat dishes.
One of Brussels’ most famous fine dining institutions, celebrated for refined Belgian-French cuisine and elegant historic interiors.
Popular traditional restaurant known for generous Belgian comfort food, beer-based dishes, and an informal, bustling atmosphere.
Historic, long-running brasserie best known for moules-frites and classic Belgian dishes in a lively central setting.
Brussels is pricier than many Belgian cities. Hotels and dining add up, but transit and casual eats are manageable.
Service is usually included. Tipping is not required, but rounding up or leaving 5-10% for great service is appreciated. Round up taxi fares; small tips are optional at cafes and bars.
Official public transport app
Brussels-Midi, Brussels -> Brussels-Central, Brussels
Find answers to the most common questions about traveling from Southampton to Brussels by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Brussels, this guide helps you travel smarter and with confidence.

Most Southampton to Brussels trains use the Southampton Central to station pair. Use this guide to compare Southampton and Brussels train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
Southampton Central has practical services for this route, including Wifi, Shopping, Parking, Dining, ATM, Taxis, Accessibility, WC, Lounge, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, and Car Rental.
Food and drink options are available at Southampton Central.
Wi-Fi is available at Southampton Central. ATMs are available at Southampton Central.
Ticket office support is available at Southampton Central.
Lost and found is available at the station.
Available at Southampton Central: Parking, Taxis, WC.
Available at Southampton Central: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Southampton Central: Staff help available: Yes, Step free access coverage: Yes, Step free access note: Step-free category A Station - This station has step-free access to all platforms. Please be aware that this station has no tactile paving on the platform edge, Accessible ticket machines: There are accessible ticket machines at this station, Accessible ticket machines note: All South Western Railway ticket machines are able to sell tickets with Disabled Persons Railcard discounts. All machines are accessible, however the station may not be so please check the station access note for further details, Accessible toilets: Yes, Ramp for train access: Yes, Wheelchairs available: Yes, Impaired mobility set down / pick up points available: Yes.
Here are some other resources that might have the information you need