- Must visit
Royal Museums of Fine Arts of Belgium
Premier fine arts complex with Old Masters, Magritte, and modern collections, essential for understanding Belgian and European art.
Omio recommends booking the flight as it is the most popular option from Southampton to Brussels among Omio's users. If you are prioritising price take the bus with prices starting from $50. For those with little time consider booking a flight which can get you there in 1h 29m. The ticket price range depends on the travel mode: a bus costs an average of $50, and a flight costs an average of $74.
Distance: 251 miles (404 km)
Most popular Flight | Bus | Driving |
|---|---|---|
$145 Average price | $63 Average price Cheapest | $51 Average price (fuel + tolls) |
4h 29m Average total duration Fastest 1h 29m Onboard + 3h 0m Additional time* | 11h 40m Average total duration 11h 10m Onboard + 30m Additional time* | 5h 54m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Southampton to Brussels:
A bus is $82 (€66) less than a flight for this route with tickets for a flight from Southampton to Brussels costing on average $145 (€117).
Other travel options to Brussels take longer:
Bus takes on average 11h 10m.
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Take a train from Southampton to Brussels and enjoy the approximately 251 miles (404 km) long journey. Find schedules and pricing options for a convenient and affordable trip.
The earliest train runs at 05:53, the last at 17:45.
Distance 251 miles (404 km) |
First train 5:53 AM |
Last train 5:45 PM |
High Season Oct - Dec |
Low Season Jan - Mar |
Discover the best of Brussels — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Brussels trip today.
Premier fine arts complex with Old Masters, Magritte, and modern collections, essential for understanding Belgian and European art.
Dedicated to surrealist René Magritte, this popular museum presents major works and context for one of Belgium’s most celebrated artists.
Leading comic art museum in a Horta-designed building, highlighting Tintin, the Smurfs, and Belgium’s influential comics culture.
Grand square at Brussels’ heart, lined with ornate guildhalls and lively events, perfect for first-time visitors and evening atmosphere.
Large urban park with the triumphal arch, museums, and wide lawns, excellent for walking, picnics, and classic city photographs.
Popular hilltop viewpoint and garden terrace with one of the best panoramas over central Brussels, especially at sunset.
Mussels steamed with white wine, celery and onion, often served with fries. A Brussels brasserie classic, especially popular in mussel season.
Double-fried potato fries, traditionally served in paper cones with sauces. They are a point of national pride and central to everyday Belgian street food.
A rich beef and onion stew braised with Belgian dark beer. It is a beloved comfort dish found in traditional Brussels restaurants.
Two-Michelin-star restaurant by chef Karen Torosyan, celebrated for pâté en croûte and inventive fine dining in an intimate setting.
Elegant Belle Époque brasserie serving refined Belgian classics, seafood and game in a grand old-world dining room.
Famous casual stop for Brussels waffles with many toppings. Popular, fast-moving and central for a classic sweet local treat.
Moderate for Western Europe: hotels can be pricey, but dining and transit are manageable for most tourists.
Service is usually included. Round up or leave 5-10% for great restaurant service; round up taxi fares; small change is fine in cafes.
Official public transport app
Brussels-Midi -> Brussels-Central
Find answers to the most common questions about traveling from Southampton to Brussels by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Brussels, this guide helps you travel smarter and with confidence.

Most Southampton to Brussels trains use the Southampton Central to station pair. Use this guide to compare Southampton and Brussels train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
Southampton Central has practical services for this route, including Wifi, Shopping, Parking, Dining, ATM, Taxis, Accessibility, WC, Lounge, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, and Car Rental.
Food and drink options are available at Southampton Central.
Wi-Fi is available at Southampton Central. ATMs are available at Southampton Central.
Ticket office support is available at Southampton Central.
Lost and found is available at the station.
Available at Southampton Central: Parking, Taxis, WC.
Available at Southampton Central: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Southampton Central: Staff help available: Yes, Step free access coverage: Yes, Step free access note: Step-free category A Station - This station has step-free access to all platforms. Please be aware that this station has no tactile paving on the platform edge, Accessible ticket machines: There are accessible ticket machines at this station, Accessible ticket machines note: All South Western Railway ticket machines are able to sell tickets with Disabled Persons Railcard discounts. All machines are accessible, however the station may not be so please check the station access note for further details, Accessible toilets: Yes, Ramp for train access: Yes, Wheelchairs available: Yes, Impaired mobility set down / pick up points available: Yes.
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