Journey information
Overview: Santa Ana, CA to San Francisco, CA flight
Flights from Santa Ana, CA to San Francisco, CA depart on average 48 times per day, taking around 1h 30m. Cheap flight tickets for this journey start at $77 (€61) but you can travel from only $41 (€33) by bus.
There are 14 flights per day. The earliest flight runs at 00:08, the last at 23:58. The fastest flight covers the 377 miles (608 km) distance in 1h 34m. May is the cheapest month to fly.
Distance 377 miles (608 km) |
Average flight duration 1h 30m |
Cheapest ticket price $77 (€61) |
Flights per day 48 |
Direct flights 14 |
Fastest flight 1h 34m |
First flight 12:08 AM |
Last flight 11:58 PM |
Cheapest Month May |
Cheapest Day Mon |
High Season Jan - Mar |
Low Season Oct - Dec |
Best time to book 7 days |
The cheapest and fastest flights from Santa Ana, CA to San Francisco, CA
Cheapest price
$412
Average price
$801
Fastest journey
1 h 26 m
Average duration
1 h 30 m
Flights per day
66
Distance
608 km
The best way to find a cheap flight ticket from Santa Ana, CA to San Francisco, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Santa Ana, CA to San Francisco, CA will cost around $801 if you buy it on the day, but the cheapest tickets can be found for only $412.
Of the 66 flights that leave Santa Ana, CA for San Francisco, CA onThu, May 07, 19 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Thu, May 07 the direct flights cover the 608 km distance in an average of 1 h 30 m but if you time it right, some flights will get you there in just 1 h 26 m .
On Thu, May 07 the longest flights will take 1 h 34 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
AA937212:52 PM1h38John Wayne Airport2:30 PMSan Francisco International Airport$4121One-way0 transfers
AA93435:27 PM1h37John Wayne Airport7:04 PMSan Francisco International Airport$4121One-way0 transfers
AA94166:36 PM1h34John Wayne Airport8:10 PMSan Francisco International Airport$4121One-way0 transfers
UA580511:10 AM1h40John Wayne Airport12:50 PMSan Francisco International Airport$4121One-way0 transfers
AA76084:23 PM1h40John Wayne Airport6:03 PMSan Francisco International Airport$4121One-way0 transfers
UA26576:39 PM1h26John Wayne Airport8:05 PMSan Francisco International Airport$4121One-way0 transfers
UA13832:38 PM1h29John Wayne Airport4:07 PMSan Francisco International Airport$4121One-way0 transfers
UA6947:20 AM1h29John Wayne Airport8:49 AMSan Francisco International Airport$4121One-way0 transfers
AA94166:36 PM1h34John Wayne Airport8:10 PMSan Francisco International Airport$4121One-way0 transfers
AS34946:36 PM1h34John Wayne Airport8:10 PMSan Francisco International Airport$4181One-way0 transfers
Travel Information
Compare bus, train, and flight for Santa Ana, CA to San Francisco, CA
Omio recommends booking the train as it is the most popular option from Santa Ana, CA to San Francisco, CA among Omio's users. If you are prioritising price take the train with prices starting from $66. For those with little time consider booking a flight which can get you there in 1h 30m. The ticket price range depends on the travel mode: a train costs an average of $66, and a flight costs an average of $77.
Distance: 377 miles (608 km)
Compare flight with
| Flight | Most popular Train | Bus | Driving |
|---|---|---|---|
$309 Average price | $73 Average price Cheapest | $105 Average price | $94 Average price (fuel + tolls) |
4h 30m Average total duration Fastest 1h 30m Onboard + 3h 0m Additional time* | 11h 42m Average total duration 11h 12m Onboard + 30m Additional time* | 11h 8m Average total duration 10h 38m Onboard + 30m Additional time* | 6h 40m Average total duration (door-to-door) |
![]() Most popular airline | ![]() Most popular train company | ![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Santa Ana, CA to San Francisco, CA:
A train is $32 (€26) less than a bus for this route with tickets for a bus from Santa Ana, CA to San Francisco, CA costing on average $105 (€84).
A train is $236 (€188) less than a flight for this route with tickets for a flight from Santa Ana, CA to San Francisco, CA costing on average $309 (€247).
Other travel options to San Francisco, CA take longer:
Bus takes on average 10h 38m.
Train takes on average 11h 12m.
Live departures
Santa Ana, CA to San Francisco, CA flight times
The table below shows live departures for Santa Ana, CA to San Francisco, CA flights for today, Wednesday, May 6. You can also manually refresh the results below to see updated flight journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
AA7608 | 4:23 PM John Wayne Airport | 1h40 | 6:03 PM San Francisco International Airport | 0 transfersDirect | |
AA2912 · AA686 | 4:23 PM John Wayne Airport | 6h13 | 10:36 PM San Francisco International Airport | 1 transfer | |
AS3465 | 4:23 PM John Wayne Airport | 1h40 | 6:03 PM San Francisco International Airport | 0 transfersDirect | |
UA5351 | 4:24 PM John Wayne Airport | 1h40 | 6:04 PM San Francisco International Airport | 0 transfersDirect | |
AS3248 | 5:27 PM John Wayne Airport | 1h37 | 7:04 PM San Francisco International Airport | 0 transfersDirect | |
AA9343 | 5:27 PM John Wayne Airport | 1h37 | 7:04 PM San Francisco International Airport | 0 transfersDirect | |
AA9416 | 6:36 PM John Wayne Airport | 1h34 | 8:10 PM San Francisco International Airport | 0 transfersDirect | |
AS3494 | 6:36 PM John Wayne Airport | 1h34 | 8:10 PM San Francisco International Airport | 0 transfersDirect | |
UA2657 | 6:39 PM John Wayne Airport | 1h26 | 8:05 PM San Francisco International Airport | 0 transfersDirect | |
AA2464+ AA4940 | 7:20 PM John Wayne Airport | 14h23 | 9:43 AM San Francisco International Airport | 1 transfer | |
UA5339 | 7:45 PM John Wayne Airport | 1h35 | 9:20 PM San Francisco International Airport | 0 transfersDirect | |
| Thursday, May 7 | |||||
AA628 · AA2423 | 6:45 AM John Wayne Airport | 5h37 | 12:22 PM San Francisco International Airport | 1 transfer | |
AA628 · AA2421 | 6:45 AM John Wayne Airport | 12h19 | 7:04 PM San Francisco International Airport | 1 transfer | |
AA628 · AA2813 | 6:45 AM John Wayne Airport | 8h40 | 3:25 PM San Francisco International Airport | 1 transfer | |
UA513 · UA1812 | 7:00 AM John Wayne Airport | 8h31 | 3:31 PM San Francisco International Airport | 1 transfer | |
UA513 · UA493 · UA548 | 7:00 AM John Wayne Airport | 11h39 | 6:39 PM San Francisco International Airport | 2 transfers | |
UA513 · UA526 · UA2047 | 7:00 AM John Wayne Airport | 10h22 | 5:22 PM San Francisco International Airport | 2 transfers | |
UA513 · UA1561 | 7:00 AM John Wayne Airport | 6h15 | 1:15 PM San Francisco International Airport | 1 transfer | |
UA513 · UA493 · UA2047 | 7:00 AM John Wayne Airport | 10h22 | 5:22 PM San Francisco International Airport | 2 transfers | |
UA513 · UA1963 · UA5732 | 7:00 AM John Wayne Airport | 10h31 | 5:31 PM San Francisco International Airport | 2 transfers | |
UA513 · UA526 · UA1799 | 7:00 AM John Wayne Airport | 8h27 | 3:27 PM San Francisco International Airport | 2 transfers | |
AS750 · AS1457 | 7:00 AM John Wayne Airport | 5h49 | 12:49 PM San Francisco International Airport | 1 transfer | |
UA694 | 7:20 AM John Wayne Airport | 1h29 | 8:49 AM San Francisco International Airport | 0 transfersDirect | |
AS3434 | 7:45 AM John Wayne Airport | 1h45 | 9:30 AM San Francisco International Airport | 0 transfersDirect | |
AA9320 | 7:45 AM John Wayne Airport | 1h45 | 9:30 AM San Francisco International Airport | 0 transfersDirect | |
UA489 · UA493 · UA2047 | 8:45 AM John Wayne Airport | 8h37 | 5:22 PM San Francisco International Airport | 2 transfers | |
UA489 · UA2633 | 8:45 AM John Wayne Airport | 8h56 | 5:41 PM San Francisco International Airport | 1 transfer | |
UA489 · UA1840 · UA5732 | 8:45 AM John Wayne Airport | 8h46 | 5:31 PM San Francisco International Airport | 2 transfers | |
UA489 · UA493 · UA548 | 8:45 AM John Wayne Airport | 9h54 | 6:39 PM San Francisco International Airport | 2 transfers | |
UA489 · UA493 · UA1603 | 8:45 AM John Wayne Airport | 10h54 | 7:39 PM San Francisco International Airport | 2 transfers | |
UA489 · UA1812 | 8:45 AM John Wayne Airport | 6h46 | 3:31 PM San Francisco International Airport | 1 transfer | |
AA2901 · AA2430 | 9:30 AM John Wayne Airport | 8h09 | 5:39 PM San Francisco International Airport | 1 transfer | |
AA2901 · AA2810 | 9:30 AM John Wayne Airport | 10h01 | 7:31 PM San Francisco International Airport | 1 transfer | |
AA2466 · AA2813 | 9:51 AM John Wayne Airport | 5h34 | 3:25 PM San Francisco International Airport | 1 transfer | |
AA2466 · AA2421 | 9:51 AM John Wayne Airport | 9h13 | 7:04 PM San Francisco International Airport | 1 transfer | |
AA2466 · AA686 | 9:51 AM John Wayne Airport | 12h47 | 10:38 PM San Francisco International Airport | 1 transfer | |
UA421 · UA4773 · UA5457 | 11:00 AM John Wayne Airport | 10h46 | 9:46 PM San Francisco International Airport | 2 transfers | |
UA421 · UA2633 | 11:00 AM John Wayne Airport | 6h41 | 5:41 PM San Francisco International Airport | 1 transfer | |
UA421 · UA5762 · UA5457 | 11:00 AM John Wayne Airport | 10h46 | 9:46 PM San Francisco International Airport | 2 transfers | |
UA421 · UA2338 · UA1267 | 11:00 AM John Wayne Airport | 10h34 | 9:34 PM San Francisco International Airport | 2 transfers | |
UA421 · UA716 · UA1603 | 11:00 AM John Wayne Airport | 8h39 | 7:39 PM San Francisco International Airport | 2 transfers | |
UA421 · UA716 · UA1267 | 11:00 AM John Wayne Airport | 10h34 | 9:34 PM San Francisco International Airport | 2 transfers | |
UA421 · UA2070 | 11:00 AM John Wayne Airport | 7h46 | 6:46 PM San Francisco International Airport | 1 transfer | |
UA421 · UA1007 | 11:00 AM John Wayne Airport | 8h52 | 7:52 PM San Francisco International Airport | 1 transfer | |
UA5805 | 11:10 AM John Wayne Airport | 1h40 | 12:50 PM San Francisco International Airport | 0 transfersDirect | |
AS1405 · AS1477 | 11:13 AM John Wayne Airport | 5h33 | 4:46 PM San Francisco International Airport | 1 transfer | |
AS3305 | 11:48 AM John Wayne Airport | 1h38 | 1:26 PM San Francisco International Airport | 0 transfersDirect | |
AA9286 | 11:48 AM John Wayne Airport | 1h38 | 1:26 PM San Francisco International Airport | 0 transfersDirect | |
AA2911 · AA686 | 12:27 PM John Wayne Airport | 10h11 | 10:38 PM San Francisco International Airport | 1 transfer | |
AA2911 · AA2421 | 12:27 PM John Wayne Airport | 6h37 | 7:04 PM San Francisco International Airport | 1 transfer | |
AA9372 | 12:52 PM John Wayne Airport | 1h38 | 2:30 PM San Francisco International Airport | 0 transfersDirect | |
AA2354 · AA2421 | 1:17 PM John Wayne Airport | 5h47 | 7:04 PM San Francisco International Airport | 1 transfer | |
AA2354 · AA686 | 1:17 PM John Wayne Airport | 9h21 | 10:38 PM San Francisco International Airport | 1 transfer | |
UA1937 · UA2338 · UA1267 | 1:22 PM John Wayne Airport | 8h12 | 9:34 PM San Francisco International Airport | 2 transfers | |
UA1937 · UA1389 | 1:22 PM John Wayne Airport | 7h47 | 9:09 PM San Francisco International Airport | 1 transfer | |
UA1937 · UA5762 · UA5457 | 1:22 PM John Wayne Airport | 8h24 | 9:46 PM San Francisco International Airport | 2 transfers | |
UA1937 · UA2123 | 1:22 PM John Wayne Airport | 9h20 | 10:42 PM San Francisco International Airport | 1 transfer | |
UA1937 · UA1007 | 1:22 PM John Wayne Airport | 6h30 | 7:52 PM San Francisco International Airport | 1 transfer | |
AA2485 · AA2320 | 1:23 PM John Wayne Airport | 9h46 | 11:09 PM San Francisco International Airport | 1 transfer | |
AA2485 · AA446 | 1:23 PM John Wayne Airport | 8h37 | 10:00 PM San Francisco International Airport | 1 transfer | |
AS712 · AS1393 | 2:06 PM John Wayne Airport | 5h43 | 7:49 PM San Francisco International Airport | 1 transfer | |
UA1383 | 2:38 PM John Wayne Airport | 1h29 | 4:07 PM San Francisco International Airport | 0 transfersDirect | |
AA2916 · AA2907 | 2:42 PM John Wayne Airport | 9h12 | 11:54 PM San Francisco International Airport | 1 transfer | |
AA2916 · AA2320 | 2:42 PM John Wayne Airport | 8h27 | 11:09 PM San Francisco International Airport | 1 transfer | |
This is the last flight of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Santa Ana, CA to San Francisco, CA by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
May 07
May 08
May 09
May 10
May 11
May 12
May 13
Why should you book Santa Ana, CA to San Francisco, CA flights with Omio?
Why book with Omio vs Alaska Airlines?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Alaska Airlines with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Santa Ana, CA to San Francisco, CA.
Why book with Omio over Skyscanner, Trip or Edreams?
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Santa Ana, CA to San Francisco, CA.
Airlines: Alaska Airlines from Santa Ana, CA to San Francisco, CAFind the best flights between Santa Ana, CA to San Francisco, CA with Omio's travel partners Alaska Airlines from $41 (€33). We can find you the best deals, schedules and tickets when comparing and booking the best trip.
Alaska Airlines
FAQs: Santa Ana, CA to San Francisco, CA Flight
Find answers to the most common questions about traveling from Santa Ana, CA to San Francisco, CA by flight. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest flight, the cheapest option, or tips for making the most of your visit at San Francisco, CA, this guide helps you travel smarter and with confidence.

- Fleet Week, a maritime celebration featuring the Blue Angels and naval ship tours
- Outside Lands, a major music festival showcasing top artists and local food
- Chinese New Year Parade, the largest Lunar New Year celebration outside Asia with colorful floats and performances
- Hardly Strictly Bluegrass, a free music festival in Golden Gate Park featuring a diverse lineup of bluegrass and folk artists.
- Golden Gate Bridge, an iconic suspension bridge offering panoramic views of the San Francisco Bay
- Alcatraz Island, a historic site featuring the infamous former prison and informative audio tours
- Fisherman's Wharf, a bustling waterfront area known for seafood, shops, and sea lions
- Golden Gate Park, a large urban park with gardens, museums, and recreational activities
- Chinatown, the oldest and one of the largest Chinatowns in North America, offering vibrant culture and cuisine.
- Thanksgiving, mild weather and a festive atmosphere with family gatherings
- Christmas, beautiful decorations and holiday spirit throughout the city
- Memorial Day, the start of summer with outdoor activities and parades
- Labor Day, a long weekend perfect for enjoying the city's parks and beaches.
- Ride a cable car through the steep streets of San Francisco for a classic city experience
- Explore the vibrant murals and street art in the Mission District
- Visit the Exploratorium, an interactive science museum perfect for all ages
- Take a scenic walk along the Embarcadero, offering views of the Bay Bridge and access to the Ferry Building Marketplace
- Enjoy a wine tasting tour in nearby Napa Valley, a short drive from the city.
popular airports
Popular airports from Santa Ana, CA to San Francisco, CA
- Free Wi-Fi available throughout the airport.
- Shops available in terminals, include Hudson News and Sunglass Hut.
- Parking available near the terminal, approximately 1.9€ ($2) per hour.
- Located in terminals; options include fast food and sit-down restaurants like McDold's and Ruby's Diner
- Available outside the terminal.
- Elevators, ramps
- Available throughout the airport.
- Hotels within walking distance, Hilton Irvine/Orange County Airport.
- No showers available.
- Admirals Club in terminal A.
- Available throughout the airport.
- Car rental services available on-site; companies include Alamo, Avis, and Hertz
- Bus Route 76, John Wayne Airport-Upper Level, 14 km
- Free Wi-Fi available throughout the airport.
- Shops are located in all terminals, including DFS Duty-Free and Burberry.
- Parking available in the Domestic and International Garages, approximately 1.9€ ($2) per 15 minutes.
- Available outside the terminal.
- Elevators, ramps, toilets.
- Available throughout the airport.
- Yes
- Lounges available, including the United Club and Delta Sky Club.
- Located in the main hall of the Domestic Terminal.
- Buses: SamTrans 292, 397, 398, KX
- Metro: BART Yellow Line
More options for your journey from Santa Ana, CA to San Francisco, CA
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