- Must visit
Vatican Museums
World-famous papal museums with the Sistine Chapel, Raphael Rooms, and major classical collections.
Cheapest price on Sep 20
lei39
Average ticket price on Sep 20
lei143
Fastest journey on Sep 20
7 h 25 m
Average journey duration on Sep 20
7 h 42 m
Buses on Sep 20
15
Distance
470 km
The best way to find a cheap bus ticket from San Donato Milanese to Rome is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from San Donato Milanese to Rome will cost around lei143 if you buy it on the day, but the cheapest tickets can be found for only lei39.
On Sun, Sep 20, we found 15 buses from San Donato Milanese to Rome, including 7 direct services.
On Sun, Sep 20 the direct buses cover the 470 km distance in an average of 7 h 42 m but if you time it right, some buses will get you there in just 7 h 25 m .
On Sun, Sep 20 the slowest buses will take 8 h 5 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
FlixBus
FlixBus
FlixBus
FlixBus
FlixBus
055
FlixBus
FlixBus
110
FlixBusOmio recommends booking the bus as it is the most popular option from San Donato Milanese to Rome among Omio's users. If you are prioritising price, take the bus, with an average ticket price of lei192 For those with little time, consider booking a flight, which has an average total journey time of 4h 49m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.1 - 0.4kg. Average ticket prices depend on the travel mode: a bus costs an average of lei192, while a flight costs an average of lei2516.
Distance: 292 miles (470 km)
Most popular Bus | Train | Flight | Driving |
|---|---|---|---|
lei192 Average price Cheapest | lei437 Average price | lei2516 Average price | lei782 Average price (fuel + tolls) |
8h 51m Average total duration 8h 21m Onboard + 30m Additional time* | 5h 54m Average total duration 5h 24m Onboard + 30m Additional time* | 4h 49m Average total duration Fastest 2h 49m Onboard + 2h 0m Additional time* | 5h 39m Average total duration (door-to-door) |
0.5 - 1.2kg CO2 emissions | 0.1 - 0.4kg CO2 emissions Lowest | - CO2 emissions | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from San Donato Milanese to Rome:
A bus is lei244 less than a train for this route with tickets for a train from San Donato Milanese to Rome costing on average lei437.
A bus is lei2323 less than a flight for this route with tickets for a flight from San Donato Milanese to Rome costing on average lei2516.
Other travel options to Rome take longer:
Train takes on average 5h 24m.
Bus takes on average 8h 21m.
Tickets start at around lei192 compared to roughly lei782 in fuel and tolls — a saving of about lei589. The journey takes 8h 21m versus 5h 39m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by Itabus, Autoservizi Salemi, Marino Autolinee, BlaBlaCar.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Itabus | Departure Time 12:30AM | Arrival Time 08:50AM | Duration 8h20 | Departure days Tue, Sat | Cheapest price lei56 |
Operator FlixBus | Departure Time 01:10AM | Arrival Time 08:40AM | Duration 7h30 | Departure days Tue, Thu, Sat, Sun | Cheapest price lei39 |
Operator BlaBlaCar | Departure Time 06:20AM | Arrival Time 12:00PM | Duration 5h40 | Departure days Tue | Cheapest price lei201 |
Operator FlixBus | Departure Time 06:50AM | Arrival Time 03:20PM | Duration 8h30 | Departure days Sat, Sun | Cheapest price lei48 |
Operator Itabus | Departure Time 08:00AM | Arrival Time 03:35PM | Duration 7h35 | Departure days Sat | Cheapest price lei168 |
Operator Itabus | Departure Time 08:45AM | Arrival Time 04:30PM | Duration 7h45 | Departure days Mon | Cheapest price lei58 |
Operator Salemi | Departure Time 08:45AM | Arrival Time 06:00PM | Duration 9h15 | Departure days Fri | Cheapest price lei283 |
Operator FlixBus | Departure Time 08:50AM | Arrival Time 05:50PM | Duration 9h00 | Departure days Tue, Thu, Sat, Sun | Cheapest price lei39 |
Operator BlaBlaCar | Departure Time 09:00AM | Arrival Time 03:50PM | Duration 6h50 | Departure days Thu | Cheapest price lei223 |
Operator FlixBus | Departure Time 09:40AM | Arrival Time 05:50PM | Duration 8h10 | Departure days Thu, Sat | Cheapest price lei151 |
Operator Salemi | Departure Time 09:45AM | Arrival Time 07:00PM | Duration 9h15 | Departure days Fri | Cheapest price lei215 |
Operator Itabus | Departure Time 10:00AM | Arrival Time 06:30PM | Duration 8h30 | Departure days Tue, Thu, Sat | Cheapest price lei34 |
Operator FlixBus | Departure Time 10:00AM | Arrival Time 06:05PM | Duration 8h05 | Departure days Sun | Cheapest price lei137 |
Operator Salemi | Departure Time 10:45AM | Arrival Time 08:00PM | Duration 9h15 | Departure days Wed | Cheapest price lei247 |
Operator FlixBus | Departure Time 12:00PM | Arrival Time 09:25PM | Duration 9h25 | Departure days Thu, Sat, Sun | Cheapest price lei129 |
Operator Itabus | Departure Time 12:25PM | Arrival Time 08:40PM | Duration 8h15 | Departure days Mon, Fri | Cheapest price lei56 |
Operator Itabus | Departure Time 12:35PM | Arrival Time 08:10PM | Duration 7h35 | Departure days Mon, Sat | Cheapest price lei50 |
Operator FlixBus | Departure Time 01:25PM | Arrival Time 09:50PM | Duration 8h25 | Departure days Sat, Sun | Cheapest price lei112 |
Operator FlixBus | Departure Time 02:25PM | Arrival Time 11:40PM | Duration 9h15 | Departure days Thu | Cheapest price lei168 |
Operator FlixBus | Departure Time 02:45PM | Arrival Time 11:00PM | Duration 8h15 | Departure days Sat, Sun | Cheapest price lei160 |
Operator Marino Autolinee | Departure Time 03:50PM | Arrival Time 11:40PM | Duration 7h50 | Departure days Tue, Thu, Sat, Sun | Cheapest price lei129 |
Operator FlixBus | Departure Time 05:05PM | Arrival Time 01:10AM | Duration 8h05 | Departure days Tue, Thu, Sat, Sun | Cheapest price lei59 |
Operator Itabus | Departure Time 08:05PM | Arrival Time 04:55AM | Duration 8h50 | Departure days Thu, Sat | Cheapest price lei101 |
Operator Itabus | Departure Time 08:35PM | Arrival Time 04:25AM | Duration 7h50 | Departure days Mon | Cheapest price lei57 |
Operator Itabus | Departure Time 09:00PM | Arrival Time 04:30AM | Duration 7h30 | Departure days Tue, Thu, Sat | Cheapest price lei56 |
Operator Marino Autolinee | Departure Time 09:05PM | Arrival Time 04:30AM | Duration 7h25 | Departure days Tue, Thu, Sat, Sun | Cheapest price lei241 |
Operator FlixBus | Departure Time 09:10PM | Arrival Time 06:10AM | Duration 9h00 | Departure days Tue, Thu, Sat, Sun | Cheapest price lei109 |
Operator FlixBus | Departure Time 09:15PM | Arrival Time 07:40AM | Duration 10h25 | Departure days Tue, Thu, Sat, Sun | Cheapest price lei134 |
Operator Itabus | Departure Time 09:35PM | Arrival Time 05:25AM | Duration 7h50 | Departure days Tue, Thu, Sat | Cheapest price lei56 |
Operator Itabus | Departure Time 11:30PM | Arrival Time 08:10AM | Duration 8h40 | Departure days Tue, Thu, Sat | Cheapest price lei56 |
Operator FlixBus | Departure Time 11:50PM | Arrival Time 08:30AM | Duration 8h40 | Departure days Tue, Thu, Sat, Sun | Cheapest price lei76 |
The table below shows live departures for San Donato Milanese to Rome buses for today, Saturday, September 19. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
2401 | 12:35 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 8h10 | 8:45 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus · FlixBus | 1:25 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 8h25 | 9:50 PM Roma, Autostazione Tiburtina | 1 transfer | |
FlixBus · FlixBus | 2:45 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 8h15 | 11:00 PM Roma, Autostazione Tiburtina | 1 transfer | |
110 | 3:50 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 7h50 | 11:40 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus | 5:05 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 8h05 | 1:10 AM Roma, Autostazione Tiburtina | 0 transfersDirect | |
2213 · 2771 | 8:05 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 8h50 | 4:55 AM Roma, Autostazione Tiburtina | 1 transfer | |
2413 | 9:00 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 7h30 | 4:30 AM Roma, Autostazione Tiburtina | 0 transfersDirect | |
055 | 9:05 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 7h25 | 4:30 AM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus · FlixBus | 9:10 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 9h00 | 6:10 AM Roma, Autostazione Tiburtina | 1 transfer | |
FlixBus · FlixBus | 9:15 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 10h25 | 7:40 AM Roma, Autostazione Tiburtina | 1 transfer | |
2421 | 9:35 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 7h50 | 5:25 AM Roma, Autostazione Tiburtina | 0 transfersDirect | |
2495 | 11:30 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 8h40 | 8:10 AM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus | 11:50 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 8h40 | 8:30 AM Roma, Autostazione Tiburtina | 0 transfersDirect | |
| Sunday, September 20 | |||||
FlixBus | 1:10 AM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 7h30 | 8:40 AM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus | 6:50 AM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 8h30 | 3:20 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus · FlixBus | 8:50 AM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 9h00 | 5:50 PM Roma, Autostazione (Metro Anagnina) | 1 transfer | |
FlixBus | 8:50 AM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 7h40 | 4:30 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus · FlixBus | 10:00 AM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 8h05 | 6:05 PM Roma, Autostazione (Metro Anagnina) | 1 transfer | |
FlixBus · FlixBus | 10:00 AM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 8h35 | 6:35 PM Roma, Autostazione Tiburtina | 1 transfer | |
FlixBus · FlixBus | 12:00 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 9h25 | 9:25 PM Roma, Autostazione Tiburtina | 1 transfer | |
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from San Donato Milanese to Rome run on average 27 times per day, taking around 8h 21m. Cheap bus tickets for this journey start at lei34 if you book in advance.
There are 20 buses per day. The earliest bus runs at 00:04, the last at 23:55. The fastest bus covers the 292 miles (470 km) distance in 6h 40m.
Distance 292 miles (470 km) |
Average bus duration 8h 21m |
Cheapest ticket price lei34 |
Buses per day 27 |
Direct buses 20 |
Fastest bus 6h 40m |
First bus 12:04 AM |
Last bus 11:55 PM |
Cheapest Month Jun |
Cheapest Day Mon |
High Season Oct - Dec |
Low Season Apr - Jun |
Busiest Day Tue |
Least Busy Day Thu |
Best time to book 1 day |
Discover the best of Rome — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Rome trip today.
World-famous papal museums with the Sistine Chapel, Raphael Rooms, and major classical collections.
Outstanding ancient sculpture and mosaic museum housed in the Palazzo dei Conservatori and Palazzo Nuovo.
Celebrated villa museum with Bernini sculptures, Caravaggio paintings, and refined garden setting.
Elegant Baroque square with Bernini's fountains, lively atmosphere, and superb people-watching.
Historic square and gathering place at the Spanish Steps, ideal for classic city views and strolls.
Charming cobbled neighborhood filled with ivy-clad lanes, churches, nightlife, and local character.
Classic Roman pasta with guanciale, egg yolk, Pecorino Romano, and black pepper. A city icon known for rich flavor without cream.
Roman pasta with guanciale, tomato, and Pecorino Romano. A traditional Lazio staple tied to shepherd cooking and bold savory flavor.
Pasta with guanciale, Pecorino Romano, and black pepper. Considered one of Rome's oldest pasta dishes and prized for its simplicity.
Three-Michelin-star dining by Niko Romito at Bulgari Hotel Roma, offering refined Italian tasting menus in an elegant setting.
Historic trattoria in Testaccio known for classic Roman pasta and quinto quarto dishes in a lively, traditional setting.
Popular casual spot famed for Roman-style pizzas and fried starters. Bustling atmosphere and a long-standing local reputation.
Moderate for Europe: stays in central Rome are pricey, but transit is cheap and meals range from affordable pizza to costly tourist-area dining.
Service may be included via coperto or servizio. Round up or leave 5-10% at restaurants if service is good; round up in taxis; small change is fine at cafés.
Official public transport app
Via Marsala, Rome -> Piazza Barberini, Rome
Find answers to the most common questions about traveling from San Donato Milanese to Rome by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Rome, this guide helps you travel smarter and with confidence.

Most San Donato Milanese to Rome buses use the Milano, San Donato - Settore B (Viale Giuseppe Impastato) to Roma, Autostazione Tiburtina station pair, with some services arriving at Fiumicino, Aeroporto Leonardo de Vinci (T3 Arrivi - Stazione degli autobus). Use this guide to compare San Donato Milanese and Rome bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Roma, Autostazione Tiburtina is 4 km from Rome city centre. Public transport options include:
Roma, Autostazione Tiburtina has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Cafes and vending machines available.
Wi-Fi is available at Roma, Autostazione Tiburtina. ATMs are aTM available near ticket office.
Ticket office support is available at Roma, Autostazione Tiburtina.
Available at Roma, Autostazione Tiburtina: Parking, Taxis, WC.
Accessibility facilities are available at Roma, Autostazione Tiburtina: Wheelchair accessible entrances and facilities.
Fiumicino, Aeroporto Leonardo de Vinci (T3 Arrivi - Stazione degli autobus) is 3 km from Rome city centre. Public transport options include:
Fiumicino, Aeroporto Leonardo de Vinci (T3 Arrivi - Stazione degli autobus) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Ristorante Italiano (in the station), Fast Food Express (in the station), Caffè del Terminal (in the station).
Free Wi-Fi. ATMs are located near the arrivals area.
Ticket office support is available at Fiumicino, Aeroporto Leonardo de Vinci (T3 Arrivi - Stazione degli autobus).
Available at Fiumicino, Aeroporto Leonardo de Vinci (T3 Arrivi - Stazione degli autobus): Parking, Taxis, WC.
Accessibility facilities are available at Fiumicino, Aeroporto Leonardo de Vinci (T3 Arrivi - Stazione degli autobus): Elevators, ramps.
Here are some other resources that might have the information you need