- Must visit
Museo Nazionale della Scienza e della Tecnologia Leonardo da Vinci
Major science and technology museum in Milan with transport, energy, and Leonardo collections; an excellent museum visit reachable from San Donato.
Cheapest price
€7
Average price
€8
Fastest journey
8 h 9 m
Average duration
8 h 12 m
Buses per day
2
Distance
470 km
The best way to find a cheap bus ticket from Rome to San Donato Milanese is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Rome to San Donato Milanese will cost around €8 if you buy it on the day, but the cheapest tickets can be found for only €7.
Of the 2 buses that leave Rome for San Donato Milanese on Thu, Aug 06, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Thu, Aug 06 the direct buses cover the 470 km distance in an average of 8 h 12 m but if you time it right, some buses will get you there in just 8 h 9 m .
On Thu, Aug 06 the slowest buses will take 8 h 15 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.




Omio recommends booking the bus as it is the most popular option from Rome to San Donato Milanese among Omio's users. If you are prioritising price take the bus with prices starting from €7. For those with little time consider booking a flight which can get you there in 1h 10m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.4kg. The ticket price range depends on the travel mode: a bus costs an average of €7, and a flight costs an average of €46.
Distance: 292 miles (470 km)
Most popular Bus | Train | Flight | Driving |
|---|---|---|---|
€17 Average price Cheapest | €52 Average price | €90 Average price | €138 Average price (fuel + tolls) |
8h 0m Average total duration 7h 30m Onboard + 30m Additional time* | 7h 14m Average total duration 6h 44m Onboard + 30m Additional time* | 4h 10m Average total duration Fastest 1h 10m Onboard + 3h 0m Additional time* | 6h 3m Average total duration (door-to-door) |
0.5 - 1.2kg CO2 emissions | 0.1 - 0.4kg CO2 emissions Lowest | - CO2 emissions | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Rome to San Donato Milanese:
A bus is €36 less than a train for this route with tickets for a train from Rome to San Donato Milanese costing on average €52.
A bus is €73 less than a flight for this route with tickets for a flight from Rome to San Donato Milanese costing on average €90.
Other travel options to San Donato Milanese take longer:
Train takes on average 6h 44m.
Bus takes on average 7h 30m.
Tickets start at around €17 compared to roughly €138 in fuel and tolls — a saving of about €122. The journey takes 7h 30m versus 6h 3m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by Itabus, Autoservizi Salemi, BlaBlaCar.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Salemi | Departure Time 04:15AM | Arrival Time 11:10AM | Duration 6h55 | Departure days Tue | Cheapest price €44 |
Operator Salemi | Departure Time 05:15AM | Arrival Time 12:10PM | Duration 6h55 | Departure days Sun | Cheapest price €38 |
Operator Salemi | Departure Time 06:15AM | Arrival Time 01:10PM | Duration 6h55 | Departure days Wed | Cheapest price €25 |
Operator FlixBus | Departure Time 06:30AM | Arrival Time 04:25PM | Duration 9h55 | Departure days Fri, Sat | Cheapest price €8 |
Operator FlixBus | Departure Time 07:30AM | Arrival Time 05:25PM | Duration 9h55 | Departure days Mon, Sun | Cheapest price €12 |
Operator Itabus | Departure Time 10:00AM | Arrival Time 06:15PM | Duration 8h15 | Departure days Mon, Thu, Fri, Sat | Cheapest price €7 |
Operator FlixBus | Departure Time 10:10AM | Arrival Time 07:10PM | Duration 9h00 | Departure days Mon | Cheapest price €7 |
Operator FlixBus | Departure Time 02:35PM | Arrival Time 11:05PM | Duration 8h30 | Departure days Mon | Cheapest price €12 |
Operator Itabus | Departure Time 02:40PM | Arrival Time 10:49PM | Duration 8h09 | Departure days Thu, Fri | Cheapest price €9 |
Operator FlixBus | Departure Time 03:35PM | Arrival Time 12:05AM | Duration 8h30 | Departure days Tue | Cheapest price €10 |
Operator Itabus | Departure Time 08:45PM | Arrival Time 05:05AM | Duration 8h20 | Departure days Tue | Cheapest price €10 |
Operator Itabus | Departure Time 09:45PM | Arrival Time 06:05AM | Duration 8h20 | Departure days Mon | Cheapest price €9 |
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Rome to San Donato Milanese run on average 29 times per day, taking around 7h 30m. Cheap bus tickets for this journey start at €7 if you book in advance.
There are 22 buses per day. The earliest bus runs at 00:10, the last at 23:55. The fastest bus covers the 292 miles (470 km) distance in 6h 55m.
Distance 292 miles (470 km) |
Average bus duration 7h 30m |
Cheapest ticket price €7 |
Buses per day 29 |
Direct buses 22 |
Fastest bus 6h 55m |
First bus 12:10 AM |
Last bus 11:55 PM |
Cheapest Month May |
Cheapest Day Fri |
High Season Apr - Jun |
Low Season Oct - Dec |
Busiest Day Fri |
Least Busy Day Wed |
Best time to book 3 days |
Discover the best of San Donato Milanese — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect San Donato Milanese trip today.
Major science and technology museum in Milan with transport, energy, and Leonardo collections; an excellent museum visit reachable from San Donato.
One of Milan’s finest modern art museums, known for Italian and international 20th-century collections in a former industrial complex.
Prestigious contemporary art museum inside a former distillery, featuring installations, exhibitions, and striking architecture by leading designers.
Main urban park of San Donato Milanese, popular for walks, relaxation, and family time; a practical green stop close to the center.
Large public park near the ENI district with paths and open lawns; good for an easy break between urban sightseeing and local exploration.
Historic old village area with a calmer atmosphere than the newer districts, suited to visitors seeking traces of the town before modern expansion.
Creamy saffron risotto from Milan, prized for its golden color and rich flavor. A defining dish of the wider Milanese area often enjoyed locally.
Breaded veal cutlet fried in butter, a classic Milanese specialty served across the area. It is one of Lombardy's most iconic traditional dishes.
Slow-braised veal shanks cooked with vegetables, wine, and broth. The marrow and gremolata make it a traditional Lombard comfort dish.
Refined restaurant with a stronger fine-dining profile, offering creative Italian cuisine and an elegant contemporary atmosphere.
Established local restaurant known for Lombard and Italian classics in a polished yet relaxed setting suitable for lunch or dinner.
Well-known pizzeria and Italian restaurant appreciated for classic pizzas, reliable service, and an easy casual atmosphere.
Moderate for the Milan area: hotels can be cheaper than central Milan, while dining and local transit are similar to other well-connected suburbs.
Service is often included or modest. Round up or leave €1-2 at cafes, 5-10% at restaurants for good service, and round up taxi fares.
Official public transport app
San Donato -> Duomo, Milan
Find answers to the most common questions about traveling from Rome to San Donato Milanese by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at San Donato Milanese, this guide helps you travel smarter and with confidence.

Most Rome to San Donato Milanese buses use the Roma, Autostazione Tiburtina to Milano, Autostazione Lampugnano station pair. Use this guide to compare Rome and San Donato Milanese bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Roma, Autostazione Tiburtina is 4 km from Rome city centre. Public transport options include:
Roma, Autostazione Tiburtina has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Cafes and vending machines available.
Wi-Fi is available at Roma, Autostazione Tiburtina. ATMs are aTM available near ticket office.
Ticket office support is available at Roma, Autostazione Tiburtina.
Available at Roma, Autostazione Tiburtina: Parking, Taxis, WC.
Accessibility facilities are available at Roma, Autostazione Tiburtina: Wheelchair accessible entrances and facilities.
Fiumicino, Aeroporto Leonardo de Vinci (T3 Arrivi - Stazione degli autobus) is 3 km from Rome city centre. Public transport options include:
Fiumicino, Aeroporto Leonardo de Vinci (T3 Arrivi - Stazione degli autobus) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Ristorante Italiano (in the station), Fast Food Express (in the station), Caffè del Terminal (in the station).
Free Wi-Fi. ATMs are located near the arrivals area.
Ticket office support is available at Fiumicino, Aeroporto Leonardo de Vinci (T3 Arrivi - Stazione degli autobus).
Available at Fiumicino, Aeroporto Leonardo de Vinci (T3 Arrivi - Stazione degli autobus): Parking, Taxis, WC.
Accessibility facilities are available at Fiumicino, Aeroporto Leonardo de Vinci (T3 Arrivi - Stazione degli autobus): Elevators, ramps.
Here are some other resources that might have the information you need