- Must visit
Museo Regionale Interdisciplinare di Messina (MuMe)
The city’s main museum, known for works by Caravaggio and Antonello da Messina, plus archaeological finds and decorative arts from the wider province.
Cheapest price
$76
Average price
$76
Fastest journey
21 h 5 m
Average duration
21 h 5 m
Buses per day
1
Distance
957 km
The best way to find a cheap bus ticket from San Donato Milanese to Messina is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from San Donato Milanese to Messina will cost around $76 if you buy it on the day, but the cheapest tickets can be found for only $76.
Of the 1 buses that leave San Donato Milanese for Messina on Mon, Jun 22, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Mon, Jun 22 the direct buses cover the 957 km distance in an average of 21 h 5 m but if you time it right, some buses will get you there in just 21 h 5 m .
On Mon, Jun 22 the slowest buses will take 21 h 5 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Omio recommends booking the bus as it is the most popular option from San Donato Milanese to Messina among Omio's users. If you are prioritising price take the bus with prices starting from $43. For those with little time consider booking a train which can get you there in 16h 49m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 1.0 - 2.4kg. The ticket price range depends on the travel mode: a bus costs an average of $43, and a train costs an average of $124.
Distance: 594 miles (957 km)
Most popular Bus | Train |
|---|---|
$62 Average price Cheapest | $146 Average price |
19h 34m Average total duration 19h 4m Onboard + 30m Additional time* | 17h 19m Average total duration Fastest 16h 49m Onboard + 30m Additional time* |
1.0 - 2.4kg CO2 emissions Lowest | - CO2 emissions |
Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from San Donato Milanese to Messina:
A bus is $85 (€70) less than a train for this route with tickets for a train from San Donato Milanese to Messina costing on average $146 (€120).
Other travel options to Messina take longer:
Bus takes on average 19h 4m.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 11:30AM | Arrival Time 05:20AM | Duration 17h50 | Departure days Wed | Cheapest price $75 |
Operator FlixBus | Departure Time 02:30PM | Arrival Time 09:10AM | Duration 18h40 | Departure days Fri, Sat | Cheapest price $43 |
Operator FlixBus | Departure Time 09:45PM | Arrival Time 06:50PM | Duration 21h05 | Departure days Mon | Cheapest price $76 |
The table below shows live departures for San Donato Milanese to Messina buses for tomorrow, Monday, June 22. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 9:45 PM San Donato Milanese | 21h05 | 6:50 PM Messina | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from San Donato Milanese to Messina run on average 3 times per day, taking around 19h 4m. Cheap bus tickets for this journey start at $43 (€35) if you book in advance.
The earliest bus runs at 10:55, the last at 23:50. The fastest bus covers the 594 miles (957 km) distance in 17h 50m.
Distance 594 miles (957 km) |
Average bus duration 19h 4m |
Cheapest ticket price $43 (€35) |
Buses per day 3 |
Fastest bus 17h 50m |
First bus 10:55 AM |
Last bus 11:50 PM |
Cheapest Month Feb |
Cheapest Day Sat |
High Season Jul - Sep |
Low Season Oct - Dec |
Best time to book 14 days |
Discover the best of Messina — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Messina trip today.
The city’s main museum, known for works by Caravaggio and Antonello da Messina, plus archaeological finds and decorative arts from the wider province.
Museum treasury linked to the cathedral, displaying liturgical objects and sacred artworks that help explain Messina’s religious and artistic history.
Contemporary art venue connected with the Horcynus Orca cultural foundation, often appreciated for exhibitions in a more alternative setting near the strait.
The symbolic heart of Messina, home to the cathedral, astronomical clock, and major monuments, making it the essential starting point for most visits.
The waterfront promenade is a popular walking area with harbour views, open space, and an easy way to experience the city’s relationship with the strait.
A panoramic viewpoint near the shrine of Cristo Re, especially popular for sunset photos over the harbour and the Strait of Messina.
Fried rice balls, usually filled with ragù, mozzarella, or butter and ham. A classic Sicilian street food widely loved in Messina.
A traditional Messina stuffed turnover, typically filled with escarole, tuma cheese, anchovies, and tomato, then baked or fried.
Messina’s signature focaccia topped with escarole, tomatoes, tuma cheese, and anchovies. It is one of the city’s most distinctive savory specialties.
A respected restaurant in Messina appreciated for refined Sicilian cooking, seafood specialties, and an elegant setting.
An established Messina seafood restaurant known for classic Sicilian dishes, polished service, and a traditional atmosphere.
Historic pastry and café venue famous for granita, cannoli, and classic Sicilian sweets in a lively, traditional setting.
Generally moderate by Italian standards. Cafes and casual meals are affordable, while seafront dining and summer stays cost more.
Service is often included or a coperto may apply. Tipping is not required, but leaving EUR 1-2 at cafes or 5-10% for very good restaurant service is appreciated. Round up taxis.
Find answers to the most common questions about traveling from San Donato Milanese to Messina by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Messina, this guide helps you travel smarter and with confidence.

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