Travel Information
Compare bus, flight, and train for Rochester, NY to Indianapolis, IN
Omio recommends booking the flight as it is the most popular option from Rochester, NY to Indianapolis, IN among Omio's users. If you are prioritising price take the bus with prices starting from $115. For those with little time consider booking a flight which can get you there in 5h 13m. The ticket price range depends on the travel mode: a bus costs an average of $115, and a flight costs an average of $163.
Distance: 500 miles (805 km)
Compare bus with
| Bus | Most popular Flight | Train |
|---|---|---|
$179 Average price Cheapest | $287 Average price | $211 Average price |
28h 18m Average total duration 27h 48m Onboard + 30m Additional time* | 8h 13m Average total duration Fastest 5h 13m Onboard + 3h 0m Additional time* | 24h 50m Average total duration 24h 20m Onboard + 30m Additional time* |
Direct Options | Direct Options | Direct Options |
Compare prices and tickets Rochester, NY to Indianapolis, IN by bus, flight, or train
Compare bus, flight, and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Bus from Rochester, NY to Indianapolis, IN
Buses from Rochester, NY to Indianapolis, IN run on average 6 times per day, taking around 27h 48m. Cheap bus tickets for this journey start at $115 (€94) if you book in advance.
The earliest bus runs at 00:15, the last at 23:55. The fastest bus covers the 500 miles (805 km) distance in 20h 50m.
Distance 500 miles (805 km) |
Average bus duration 27h 48m |
Cheapest ticket price $115 (€94) |
Buses per day 6 |
Fastest bus 20h 50m |
First bus 00:15 |
Last bus 23:55 |
Cheapest month Nov |
Cheapest day Tue |
High season Oct - Dec |
Low season Jul - Sep |
Best day to book ahead 3 days |
FAQs: Bus from Rochester, NY to Indianapolis, IN
Find answers to the most common questions about traveling from Rochester, NY to Indianapolis, IN by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Indianapolis, IN, this guide helps you travel smarter and with confidence.

- Indianapolis Motor Speedway, a historic racing circuit known for hosting the Indianapolis 500
- The Children's Museum of Indianapolis, the world's largest children's museum featuring interactive exhibits
- Indianapolis Zoo, a popular attraction with diverse animal exhibits and a botanical garden
- Indiana State Museum, showcasing the state's history, art, and science through various exhibits
- White River State Park, a sprawling urban park offering trails, gardens, and cultural attractions.
- Indianapolis Museum of Art at Newfields, a vast art museum with extensive collections and beautiful gardens
- Attend a race at the Indianapolis Motor Speedway, home of the iconic Indy 500
- Explore the interactive exhibits and educational programs at The Children's Museum of Indianapolis
- Visit the dolphin pavilion and animal habitats at the Indianapolis Zoo
- Enjoy a walk along the canal and cultural attractions at White River State Park.
popular bus stations
Popular bus stations from Rochester, NY to Indianapolis, IN
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