The cheapest and fastest buses from Roanoke, VA to Louisville, KY
Cheapest price
$188
Average price
$188
Fastest journey
12 h 40 m
Average duration
12 h 40 m
Buses per day
1
Distance
523 km
The best way to find a cheap bus ticket from Roanoke, VA to Louisville, KY is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Roanoke, VA to Louisville, KY will cost around $188 if you buy it on the day, but the cheapest tickets can be found for only $188.
Of the 1 buses that leave Roanoke, VA for Louisville, KY on Thu, Jul 02, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Thu, Jul 02 the direct buses cover the 523 km distance in an average of 12 h 40 m but if you time it right, some buses will get you there in just 12 h 40 m .
On Thu, Jul 02 the slowest buses will take 12 h 40 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
4:50 PM12h40Roanoke, VA5:30 AMLouisville, KY$1881One-way0 transfers
4:50 PM12h40Roanoke, VA5:30 AMLouisville, KY$1881One-way0 transfers
Travel Information
Compare bus for Roanoke, VA to Louisville, KY
Omio recommends booking the bus as it is the most popular option from Roanoke, VA to Louisville, KY among Omio's users. If you are prioritising price take the bus with prices starting from $188. For those with little time consider booking a bus which can get you there in 11h 0m. The ticket price range depends on the travel mode: a bus costs an average of $188, and a bus costs an average of $188.
Distance: 324 miles (523 km)
Compare bus with
Most popular Bus | Driving |
|---|---|
$188 Average price Cheapest | $84 Average price (fuel + tolls) |
11h 30m Average total duration Fastest 11h 0m Onboard + 30m Additional time* | 6h 26m Average total duration (door-to-door) |
![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options |
Other travel options to Louisville, KY take longer:
Train takes on average 21h 3m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
Roanoke, VA to Louisville, KY Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound USA | Departure Time 12:50PM | Arrival Time 02:55AM | Duration 14h05 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price $103 |
Operator Greyhound | Departure Time 04:50PM | Arrival Time 05:30AM | Duration 12h40 | Departure days Thu | Cheapest price $188 |
Live departures
Roanoke, VA to Louisville, KY bus times
The table below shows live departures for Roanoke, VA to Louisville, KY buses for tomorrow, Thursday, July 2. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 4:50 PM Roanoke, VA | 12h40 | 5:30 AM Louisville, KY | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Roanoke, VA to Louisville, KY by bus
Compare bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Jul 02
Jul 03
Jul 04
Jul 05
Jul 06
Jul 07
Jul 08
Why should you book Roanoke, VA to Louisville, KY buses with Omio?
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
Journey information
Overview: Bus from Roanoke, VA to Louisville, KY
Buses from Roanoke, VA to Louisville, KY run on average 1 times per day, taking around 11h 0m. Cheap bus tickets for this journey start at $188 (€155) if you book in advance.
The earliest bus runs at 12:50, the last at 14:20. The fastest bus covers the 324 miles (523 km) distance in 12h 40m.
Distance 324 miles (523 km) |
Average bus duration 11h 0m |
Cheapest ticket price $188 (€155) |
Buses per day 1 |
Fastest bus 12h 40m |
First bus 12:50 PM |
Last bus 2:20 PM |
Cheapest Month Oct |
Cheapest Day Wed |
High Season Jan - Mar |
Low Season Apr - Jun |
Bus providers: Greyhound from Roanoke, VA to Louisville, KYYou can travel by bus between Roanoke, VA to Louisville, KY with Greyhound for as low as $188 (€155). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
FAQs: Bus from Roanoke, VA to Louisville, KY
Find answers to the most common questions about traveling from Roanoke, VA to Louisville, KY by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Louisville, KY, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from Roanoke, VA to Louisville, KY
Most Roanoke, VA to Louisville, KY buses use the Roanoke, Third Street Station to Louisville, W Broadway (Greyhound Bus Station) station pair. Use this guide to compare Roanoke, VA and Louisville, KY bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Getting to Louisville, W Broadway (Greyhound Bus Station) from Louisville city centre
Most popular bus connections from Roanoke, VA
More options for your journey from Roanoke, VA to Louisville, KY
Here are some other resources that might have the information you need
