Travel Information
Compare bus and flight for Roanoke, VA to Louisville, KY
Omio recommends booking the bus as it is the most popular option from Roanoke, VA to Louisville, KY among Omio's users. If you are prioritising price take the bus with prices starting from $163. For those with little time consider booking a flight which can get you there in 6h 39m. The ticket price range depends on the travel mode: a bus costs an average of $163, and a flight costs an average of $425.
Distance: 324 miles (523 km)
Compare bus with
Most popular Bus | Flight |
|---|---|
$163 Average price Cheapest | $425 Average price |
11h 30m Average total duration 11h 0m Onboard + 30m Additional time* | 9h 39m Average total duration Fastest 6h 39m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options |
This is compared to other travel options from Roanoke, VA to Louisville, KY:
A bus is $262 (€209) less than a flight for this route with tickets for a flight from Roanoke, VA to Louisville, KY costing on average $425 (€339).
Other travel options to Louisville, KY take longer:
Bus takes on average 11h 0m.
Train takes on average 21h 3m.
Compare prices and tickets Roanoke, VA to Louisville, KY by bus or flight
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Roanoke, VA to Louisville, KY buses with Omio?
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus and flight to ensure you get the best deal for traveling from Roanoke, VA to Louisville, KY.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including bus and flight to find the ideal travel option from Roanoke, VA to Louisville, KY.
Journey information
Overview: Bus from Roanoke, VA to Louisville, KY
Buses from Roanoke, VA to Louisville, KY run on average 1 times per day, taking around 11h 0m. Cheap bus tickets for this journey start at $163 (€130) if you book in advance.
The earliest bus runs at 12:50, the last at 14:20. The fastest bus covers the 324 miles (523 km) distance in 12h 40m.
Distance 324 miles (523 km) |
Average bus duration 11h 0m |
Cheapest ticket price $163 (€130) |
Buses per day 1 |
Fastest bus 12h 40m |
First bus 12:50 PM |
Last bus 2:20 PM |
Cheapest Month Oct |
Cheapest Day Wed |
High Season Jan - Mar |
Low Season Apr - Jun |
Bus providers: Greyhound from Roanoke, VA to Louisville, KYYou can travel by bus between Roanoke, VA to Louisville, KY with Greyhound for as low as $163 (€130). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
FAQs: Bus from Roanoke, VA to Louisville, KY
Find answers to the most common questions about traveling from Roanoke, VA to Louisville, KY by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Louisville, KY, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from Roanoke, VA to Louisville, KY
Most popular bus connections from Roanoke, VA
More options for your journey from Roanoke, VA to Louisville, KY
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