The best time to book your bus from Prague to Istanbul is 21 days before departure. See how prices for buses change on the Prague to Istanbul route.
Prices are for one-way tickets for one passenger from Prague to Istanbul per month. Insights are sourced from fares found by Omio users in the last 12 months. Current prices may differ as prices vary depending on the time of day, class or how far in advance you book your bus from Prague to Istanbul.