- Must visit
AKG Art Museum
Major art museum with a strong modern and contemporary collection in a restored and expanded campus.
Cheapest price
$158
Average price
$202
Fastest journey
23 h 25 m
Average duration
1 d 2 h 23 m
Buses per day
5
Distance
868 km
The best way to find a cheap bus ticket from Charlotte, NC to Buffalo, NY is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Charlotte, NC to Buffalo, NY will cost around $202 if you buy it on the day, but the cheapest tickets can be found for only $158.
Of the 5 buses that leave Charlotte, NC for Buffalo, NY on Mon, Jun 01, 5 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Mon, Jun 01 the direct buses cover the 868 km distance in an average of 1 d 2 h 23 m but if you time it right, some buses will get you there in just 23 h 25 m .
On Mon, Jun 01 the slowest buses will take 1 d 9 h 50 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.










Omio recommends booking the train as it is the most popular option from Charlotte, NC to Buffalo, NY among Omio's users. If you are prioritising price take the bus with prices starting from $104. For those with little time consider booking a flight which can get you there in 2h 54m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.3 - 0.8kg. The ticket price range depends on the travel mode: a bus costs an average of $104, and a flight costs an average of $306.
Distance: 539 miles (868 km)
| Bus | Most popular Train | Flight | Driving |
|---|---|---|---|
$191 Average price Cheapest | $300 Average price | $441 Average price | $146 Average price (fuel + tolls) |
22h 14m Average total duration 21h 44m Onboard + 30m Additional time* | 22h 36m Average total duration 22h 6m Onboard + 30m Additional time* | 5h 54m Average total duration Fastest 2h 54m Onboard + 3h 0m Additional time* | 9h 50m Average total duration (door-to-door) |
0.9 - 2.2kg CO2 emissions | 0.3 - 0.8kg CO2 emissions Lowest | 2.6 - 5.2kg CO2 emissions | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Charlotte, NC to Buffalo, NY:
A bus is $109 (€88) less than a train for this route with tickets for a train from Charlotte, NC to Buffalo, NY costing on average $300 (€241).
A bus is $251 (€202) less than a flight for this route with tickets for a flight from Charlotte, NC to Buffalo, NY costing on average $441 (€355).
Other travel options to Buffalo, NY take longer:
Bus takes on average 21h 44m.
Train takes on average 22h 6m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 01:25AM | Arrival Time 10:30PM | Duration 21h05 | Departure days Mon, Wed, Thu, Sat, Sun | Cheapest price $150 |
Operator Greyhound | Departure Time 02:25AM | Arrival Time 12:25AM | Duration 22h00 | Departure days Wed, Sun | Cheapest price $186 |
Operator FlixBus | Departure Time 03:40AM | Arrival Time 02:45AM | Duration 23h05 | Departure days Thu | Cheapest price $169 |
Operator FlixBus | Departure Time 03:59AM | Arrival Time 02:25AM | Duration 22h26 | Departure days Tue, Fri, Sat | Cheapest price $168 |
Operator FlixBus | Departure Time 05:10AM | Arrival Time 04:35AM | Duration 23h25 | Departure days Mon, Sat | Cheapest price $184 |
Operator FlixBus | Departure Time 06:10AM | Arrival Time 05:35AM | Duration 23h25 | Departure days Fri | Cheapest price $196 |
Operator Greyhound | Departure Time 09:20AM | Arrival Time 12:15PM | Duration 26h55 | Departure days Sat | Cheapest price $173 |
Operator Greyhound | Departure Time 11:55AM | Arrival Time 09:45PM | Duration 33h50 | Departure days Mon | Cheapest price $268 |
Operator Greyhound | Departure Time 01:20PM | Arrival Time 12:15PM | Duration 22h55 | Departure days Thu | Cheapest price $239 |
Operator Greyhound | Departure Time 05:20PM | Arrival Time 08:25PM | Duration 27h05 | Departure days Wed | Cheapest price $185 |
Operator Greyhound | Departure Time 10:05PM | Arrival Time 09:30PM | Duration 23h25 | Departure days Mon | Cheapest price $158 |
Operator FlixBus | Departure Time 10:05PM | Arrival Time 10:30PM | Duration 24h25 | Departure days Tue | Cheapest price $185 |
Operator FlixBus | Departure Time 11:05PM | Arrival Time 11:30PM | Duration 24h25 | Departure days Mon, Thu | Cheapest price $163 |
The table below shows live departures for Charlotte, NC to Buffalo, NY buses for tomorrow, Monday, June 1. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 3:59 AM Charlotte, NC | 24h36 | 4:35 AM Buffalo, NY | 0 transfersDirect | |
![]() | 5:10 AM Charlotte, NC | 23h45 | 4:55 AM Buffalo, NY | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Charlotte, NC to Buffalo, NY run on average 15 times per day, taking around 21h 44m. Cheap bus tickets for this journey start at $104 (€84) if you book in advance.
The earliest bus runs at 00:55, the last at 23:55. The fastest bus covers the 539 miles (868 km) distance in 21h 5m.
Distance 539 miles (868 km) |
Average bus duration 21h 44m |
Cheapest ticket price $104 (€84) |
Buses per day 15 |
Fastest bus 21h 5m |
First bus 12:55 AM |
Last bus 11:55 PM |
Cheapest Month Sep |
Cheapest Day Wed |
High Season Apr - Jun |
Low Season Oct - Dec |
Busiest Day Sat |
Least Busy Day Sat |
Best time to book 14 days |
Discover the best of Buffalo — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Buffalo trip today.
Major art museum with a strong modern and contemporary collection in a restored and expanded campus.
Architectural museum complex and one of Frank Lloyd Wright's most important Prairie School works.
Family-friendly science museum with natural history, space, health, and hands-on exhibits.
Popular waterfront district with promenades, events, seasonal activities, and harbor views.
Frederick Law Olmsted-designed urban park with trails, lake views, and major cultural institutions nearby.
Walkable neighborhood known for historic homes, local shops, and lively street life.
Crispy chicken wings tossed in a buttery cayenne pepper hot sauce, traditionally served with celery and blue cheese. Buffalo's signature dish was created here and remains a local essential.
Roast beef sandwich on a kummelweck roll topped with coarse salt and caraway seeds, usually served with horseradish and au jus. It is one of Buffalo's most iconic regional sandwiches.
A light, airy toffee-like candy coated in chocolate. It is a classic Western New York sweet strongly associated with Buffalo confectioners.
Classic traditional restaurant best known for Beef On Weck, with old-school service and a long-standing Buffalo reputation.
Well-known bistro-style restaurant offering a more upscale meal in a polished but comfortable setting, popular for date nights and special occasions.
Long-established local favorite specializing in spicy Buffalo wings. Casual, busy, and highly regarded by locals for heat and consistency.
Moderate by U.S. standards. Casual dining and coffee are reasonable, while hotels and fine dining cost more in peak periods.
Tip 18-20% at restaurants; 15-20% for taxis. USD 1-2 per drink at bars, USD 1-2 per bag for hotel staff, and round up for casual service.
Find answers to the most common questions about traveling from Charlotte, NC to Buffalo, NY by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Buffalo, NY, this guide helps you travel smarter and with confidence.

Here are some other resources that might have the information you need