- Must visit
Newfields
Major campus combining the Indianapolis Museum of Art, gardens, and seasonal installations. Strong all-around choice for art, design, and outdoor strolling.
Omio recommends booking the flight as it is the most popular option from Lafayette, LA to Indianapolis, IN among Omio's users. If you are prioritising price take the bus with prices starting from $161. For those with little time consider booking a flight which can get you there in 4h 39m. The ticket price range depends on the travel mode: a bus costs an average of $161, and a flight costs an average of $393.
Distance: 737 miles (1187 km)
| Bus | Most popular Flight | Driving |
|---|---|---|
$205 Average price Cheapest | $479 Average price | $172 Average price (fuel + tolls) |
29h 28m Average total duration 28h 58m Onboard + 30m Additional time* | 7h 39m Average total duration Fastest 4h 39m Onboard + 3h 0m Additional time* | 13h 11m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Lafayette, LA to Indianapolis, IN:
A bus is $274 (€224) less than a flight for this route with tickets for a flight from Lafayette, LA to Indianapolis, IN costing on average $479 (€392).
Other travel options to Indianapolis, IN take longer:
Bus takes on average 28h 58m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 12:20AM | Arrival Time 09:45AM | Duration 33h25 | Departure days Thu | Cheapest price $245 |
Operator Greyhound | Departure Time 02:00AM | Arrival Time 08:25AM | Duration 29h25 | Departure days Thu | Cheapest price $111 |
Operator Greyhound | Departure Time 02:25AM | Arrival Time 09:30AM | Duration 30h05 | Departure days Thu | Cheapest price $114 |
Operator FlixBus | Departure Time 02:25AM | Arrival Time 08:25AM | Duration 29h00 | Departure days Thu | Cheapest price $112 |
Operator Greyhound | Departure Time 09:35AM | Arrival Time 12:05PM | Duration 25h30 | Departure days Thu | Cheapest price $112 |
Operator Greyhound | Departure Time 06:20PM | Arrival Time 04:45AM | Duration 33h25 | Departure days Thu | Cheapest price $125 |
Operator FlixBus | Departure Time 06:20PM | Arrival Time 08:25AM | Duration 37h05 | Departure days Thu | Cheapest price $108 |
Operator Greyhound | Departure Time 10:25PM | Arrival Time 01:25AM | Duration 27h00 | Departure days Wed | Cheapest price $210 |
Operator FlixBus | Departure Time 10:35PM | Arrival Time 08:25AM | Duration 32h50 | Departure days Thu | Cheapest price $103 |
Operator Greyhound | Departure Time 10:35PM | Arrival Time 04:45AM | Duration 29h10 | Departure days Thu | Cheapest price $123 |
Operator FlixBus | Departure Time 11:55PM | Arrival Time 02:25AM | Duration 26h30 | Departure days Fri | Cheapest price $161 |
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Lafayette, LA to Indianapolis, IN run on average 10 times per day, taking around 28h 58m. Cheap bus tickets for this journey start at $161 (€132) if you book in advance.
The earliest bus runs at 02:00, the last at 23:55. The fastest bus covers the 737 miles (1187 km) distance in 26h 30m.
Distance 737 miles (1187 km) |
Average bus duration 28h 58m |
Cheapest ticket price $161 (€132) |
Buses per day 10 |
Fastest bus 26h 30m |
First bus 2:00 AM |
Last bus 11:55 PM |
Cheapest Month May |
Cheapest Day Mon |
High Season Jan - Mar |
Low Season Jul - Sep |
Best time to book 7 days |
Discover the best of Indianapolis — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Indianapolis trip today.
Major campus combining the Indianapolis Museum of Art, gardens, and seasonal installations. Strong all-around choice for art, design, and outdoor strolling.
One of the world’s largest children’s museums, known for immersive science, history, and culture exhibits that also appeal to many adults.
Respected museum focused on Native American and Western art, with strong permanent collections and rotating exhibitions.
Iconic downtown circle and gathering place centered on the city’s best-known monument. A top orientation point and classic Indianapolis photo stop.
Popular pedestrian route along the downtown canal, lined with museums, public art, paddle boats, and skyline views.
Large urban park complex connecting major attractions, trails, green spaces, and event venues near downtown.
Indiana’s signature sandwich: a breaded and fried pork cutlet served on a bun, often comically larger than the bread. It is a classic Central Indiana comfort food.
A St. Elmo Steak House staple in Indianapolis, known for jumbo shrimp served with an intensely spicy horseradish cocktail sauce. It is one of the city’s most famous signature dishes.
Often called Indiana’s state pie, this simple custard-style pie is made with cream, sugar, and nutmeg. It is a beloved Hoosier dessert with deep local roots.
Historic downtown steakhouse famous for shrimp cocktail, steaks, and classic old-school service. One of Indianapolis’s most iconic dining rooms.
Well-known modern restaurant in Fletcher Place serving seasonal American cooking with a chef-driven menu in a stylish, industrial space.
Established upscale-casual spot related to St. Elmo, known for steaks, shrimp cocktail, and polished service in a more relaxed setting.
Generally moderate for U.S. travel. Hotels vary by events; dining and transport are usually manageable.
Tip 18-20% at restaurants; 20%+ for great service. Tip bartenders USD 1-2 per drink, taxis 10-15%, hotel staff USD 2-5, and round up for cafes if desired.
Find answers to the most common questions about traveling from Lafayette, LA to Indianapolis, IN by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Indianapolis, IN, this guide helps you travel smarter and with confidence.

Most Lafayette, LA to Indianapolis, IN buses use the Lafayette, Lee Ave (Greyhound Bus Station) to Indianapolis, Illinois St (Greyhound Bus Station) station pair, with some services arriving at Indianapolis, E Washington St / N Delaware St (City/County Building). Use this guide to compare Lafayette, LA and Indianapolis, IN bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
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