- Must visit
San Antonio Museum of Art
A premier collection of Greek, Roman, Egyptian, and Asian art in a striking riverside complex, ideal for art lovers and curious first-time visitors.
The best way to find a cheap bus ticket from Lafayette, LA to San Antonio, TX is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Lafayette, LA to San Antonio, TX will cost around $114 if you buy it on the day, but the cheapest tickets can be found for only $114.
On Tue, Nov 03, we found 1 buses from Lafayette, LA to San Antonio, TX, including 1 direct services.
On Tue, Nov 03 the direct buses cover the 631 km distance in an average of 7 h 35 m but if you time it right, some buses will get you there in just 7 h 35 m .
On Tue, Nov 03 the slowest buses will take 7 h 35 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

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Buses from Lafayette, LA to San Antonio, TX run on average 5 times per day, taking around 7h 49m. Cheap bus tickets for this journey start at $47 if you book in advance.
There are 1 buses per day. The earliest bus runs at 01:05, the last at 22:10. The fastest bus covers the 392 miles (631 km) distance in 7h 20m.
Plan this route
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Lafayette, LA to San Antonio, TX.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 01:30AM | Arrival Time 12:55PM | Duration 11h25 | Departure days Fri, Sat | Cheapest price $77 |
Operator Greyhound | Departure Time 02:20AM | Arrival Time 10:25AM | Duration 8h05 | Departure days Tue | Cheapest price $183 |
Operator FlixBus | Departure Time 06:30AM | Arrival Time 05:55PM | Duration 11h25 | Departure days Wed | Cheapest price $173 |
Operator Greyhound | Departure Time 07:05AM | Arrival Time 03:50PM | Duration 8h45 | Departure days Fri, Sat | Cheapest price $76 |
Operator FlixBus | Departure Time 08:20AM | Arrival Time 07:05PM | Duration 10h45 | Departure days Sat | Cheapest price $76 |
Operator Greyhound | Departure Time 09:20AM | Arrival Time 06:05PM | Duration 8h45 | Departure days Fri, Sat | Cheapest price $76 |
Operator FlixBus | Departure Time 10:10AM | Arrival Time 10:05PM | Duration 11h55 | Departure days Fri, Sat | Cheapest price $76 |
Operator Greyhound | Departure Time 01:05PM | Arrival Time 09:20PM | Duration 8h15 | Departure days Thu | Cheapest price $155 |
Operator Greyhound | Departure Time 02:20PM | Arrival Time 11:05PM | Duration 8h45 | Departure days Thu | Cheapest price $117 |
Operator FlixBus | Departure Time 03:25PM | Arrival Time 10:45PM | Duration 7h20 | Departure days Fri, Sat | Cheapest price $57 |
Operator FlixBus | Departure Time 08:25PM | Arrival Time 04:00AM | Duration 7h35 | Departure days Mon, Tue, Sun | Cheapest price $65 |
Operator FlixBus | Departure Time 09:25PM | Arrival Time 05:00AM | Duration 7h35 | Departure days Mon | Cheapest price $67 |
Operator Greyhound | Departure Time 09:25PM | Arrival Time 05:25AM | Duration 8h00 | Departure days Fri, Sat | Cheapest price $76 |
The table below shows live departures for Lafayette, LA to San Antonio, TX buses for today, Monday, November 2. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 8:25 PM Lafayette, LA | 7h35 | 4:00 AM San Antonio, TX | 0 transfersDirect | |
![]() | 9:25 PM Lafayette, LA | 7h35 | 5:00 AM San Antonio, TX | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Buses from Lafayette, LA to San Antonio, TX with Greyhound and FlixBus. Overnight buses available on this route with Greyhound and FlixBus. Use the details below to compare onboard facilities.
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
Discover the best of San Antonio, TX — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect San Antonio, TX trip today.
A premier collection of Greek, Roman, Egyptian, and Asian art in a striking riverside complex, ideal for art lovers and curious first-time visitors.
This leading Latinx art museum showcases contemporary and historic works, making it one of the city’s most distinctive cultural stops.
Housed in a former brewery, this contemporary art museum presents rotating exhibitions in one of San Antonio’s most atmospheric spaces.
The city’s signature pedestrian corridor links shops, boats, bridges, and historic architecture, making it San Antonio’s essential walking experience.
This artsy, fast-evolving district mixes galleries, murals, boutiques, and nightlife with a strong local identity near the river.
A lively downtown plaza framed by major civic buildings, it is best known for events, fountains, and the nightly cathedral light show nearby.
Puffy tacos are San Antonio’s signature dish: crisp, airy fried corn tortillas filled with picadillo, chicken, or beans, rooted in local Tex-Mex history.
Barbacoa is slow-cooked beef, often served on weekends in breakfast tacos. It is a beloved South Texas tradition with deep Mexican roots.
Breakfast tacos are a daily staple in San Antonio, usually filled with egg, potato, bean, bacon, or chorizo in flour or corn tortillas.
Refined River Walk restaurant serving upscale South Texas and Mexican cuisine. Elegant atmosphere with a long-standing fine dining reputation.
Popular breakfast and lunch spot known for house-made tortillas, tacos, and classic San Antonio Tex-Mex in a relaxed setting.
Beloved market restaurant for authentic Mexican dishes, fresh tortillas, and bakery items. Bustling, traditional atmosphere.
Moderate for a major U.S. city. Hotels and dining are usually cheaper than New York or San Francisco, while car use can add costs because transit is limited.
Tip 18-20% at restaurants, 10-15% for taxis, and $1-$2 per drink or coffee if there is table or bar service.
Official public transport app
UTSA East Campus Lot 1 -> Downtown San Antonio
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in San Antonio, TX.
Find answers to the most common questions about traveling from Lafayette, LA to San Antonio, TX by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at San Antonio, TX, this guide helps you travel smarter and with confidence.

Most Lafayette, LA to San Antonio, TX buses use the Lafayette, Lee Ave (Greyhound Bus Station) to San Antonio, N St Mary's St (Greyhound) station pair. Use this guide to compare Lafayette, LA and San Antonio, TX bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Lafayette, Lee Ave (Greyhound Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Lafayette, Lee Ave (Greyhound Bus Station). ATMs are available at Lafayette, Lee Ave (Greyhound Bus Station).
Ticket office support is available at Lafayette, Lee Ave (Greyhound Bus Station).
Available at Lafayette, Lee Ave (Greyhound Bus Station): Parking, Taxis, WC.
Accessibility facilities are available at Lafayette, Lee Ave (Greyhound Bus Station): Ramp access available.
Lafayette, TA Travel center is 3 km from Lafayette city centre. Public transport options include:
Lafayette, TA Travel center has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: There is a fast-food restaurant at the station.
Free Wi-Fi is available in the waiting area. ATMs are an ATM is available near the main entrance.
Ticket office support is available at Lafayette, TA Travel center.
Available at Lafayette, TA Travel center: Parking, Taxis, WC.
Accessibility facilities are available at Lafayette, TA Travel center: The station is wheelchair accessible.
San Antonio, N St Mary's St (Greyhound) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at San Antonio, N St Mary's St (Greyhound). ATMs are available at San Antonio, N St Mary's St (Greyhound).
Ticket office support is available at San Antonio, N St Mary's St (Greyhound).
Available at San Antonio, N St Mary's St (Greyhound): Parking, Taxis, WC.
Accessibility facilities are available at San Antonio, N St Mary's St (Greyhound): Limited accessibility features.
Check bus stations information for Lafayette, LA and San Antonio, TX, including where buses depart and arrive on this route.