Harrisburg, PA to Spartanburg, SC bus

Fri, Nov 07
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FlixBus
Alsa
BlaBlaCar Bus
Rede Expressos
SARFA S.L.
1,000+ travel companies
FlixBus
Alsa
BlaBlaCar Bus
Rede Expressos
SARFA S.L.
1,000+ travel companies
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Travel Information

Compare bus for Harrisburg, PA to Spartanburg, SC

Omio recommends booking the train as it is the most popular option from Harrisburg, PA to Spartanburg, SC among Omio's users. If you are prioritising price take the bus with prices starting from €88. For those with little time consider booking a flight which can get you there in 3h 30m. The ticket price range depends on the travel mode: a bus costs an average of €88, and a flight costs an average of €164.

Distance: 459 miles (740 km)

Compare bus with

Bus
Most popular
Train
Flight

€88

Average price

Cheapest

€142

Average price

€164

Average price

22h 10m

Average total duration

21h 40m

Onboard

+

30m

Additional time*

15h 7m

Average total duration

14h 37m

Onboard

+

30m

Additional time*

6h 30m

Average total duration

Fastest

3h 30m

Onboard

+

3h 0m

Additional time*

Direct Options

Direct Options

Direct Options

Journey information

Overview: Bus from Harrisburg, PA to Spartanburg, SC

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Buses from Harrisburg, PA to Spartanburg, SC run on average 5 times per day, taking around 21h 40m. Cheap bus tickets for this journey start at $109 (€88) if you book in advance.

The earliest bus runs at 03:40, the last at 21:05. The fastest bus covers the 459 miles (740 km) distance in 21h 40m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
459 miles (740 km)
Average bus duration
21h 40m
Cheapest ticket price
$109 (€88)
Buses per day
5
Fastest bus
21h 40m
First bus
03:40
Last bus
21:05
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

FAQs: Bus from Harrisburg, PA to Spartanburg, SC

Find answers to the most common questions about traveling from Harrisburg, PA to Spartanburg, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Spartanburg, SC, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Harrisburg, PA to Spartanburg, SC can start from as little as $108 (€88) when you book in advance. The average bus ticket price for Harrisburg, PA to Spartanburg, SC is $108 (€88); however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Harrisburg, PA to Spartanburg, SC is 16 h 50 min   to travel the 459 mile (740 km) long journey, with around there are 4 buses per day. Journey times can vary on weekends and holidays.
The first bus from Harrisburg, PA to Spartanburg, SC leaves at 3: 25AM. Plan your trip with the Journey Planner   from Omio.
The last bus from Harrisburg, PA to Spartanburg, SC leaves at 8: 35PM.
The cheapest month to travel from Harrisburg, PA to Spartanburg, SC by bus is October.
It's helpful to compare your options as there are 3 ways to travel to Spartanburg, SC from Harrisburg, PA including taking a bus, train or flight.
No, the bus from Harrisburg, PA to Spartanburg, SC has no accessibility options.
No, there are no bathrooms on board the bus from Harrisburg, PA to Spartanburg, SC.
No, bikes are not allowed on board the bus from Harrisburg, PA to Spartanburg, SC.

To find the cheapest bus tickets for your trip from Harrisburg, PA to Spartanburg, SC, follow these tips:

  • Book in advance: Tickets are often cheaper when booked early.
  • Be flexible with dates and times: Traveling during off-peak hours or on weekdays can help you save money.
  • Use our search filters: Sort results by price to quickly identify the most affordable options.
  • Look for special deals or discounts: Check for promotions or discounts available on our website and app.

    • Start your search now and compare ticket prices to find the best deal!

    Yes, there is food available to purchase on board the bus from Harrisburg, PA to Spartanburg, SC.
    No, luggage for the bus from Harrisburg, PA to Spartanburg, SC needs to be booked in addition.
    No, there are no additional luggage options for the bus from Harrisburg, PA to Spartanburg, SC.
    Unfortunately, pets are not allowed on the bus from Harrisburg, PA to Spartanburg, SC.
    No, there are no USB plugs on board the bus from Harrisburg, PA to Spartanburg, SC.
    No, there is no WiFi on board the bus from Harrisburg, PA to Spartanburg, SC.

    popular bus stations

    Popular bus stations from Harrisburg, PA to Spartanburg, SC

    Harrisburg
    Spartanburg
    The major bus station for departures in Harrisburg is Harrisburg, Market St (Bus Station). Find all the information you need to know about services, amenities and connections at Harrisburg, Market St (Bus Station) for your trip from Harrisburg to Spartanburg.
    Harrisburg, Market St (Bus Station)
    information
    Harrisburg, Chestnut Street / South 4th Street
    information

    More options for your journey from Harrisburg, PA to Spartanburg, SC

    Here are some other resources that might have the information you need

    Tickets and more information for coaches to Harrisburg, PA

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    Most popular bus connections to Spartanburg, SC

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