Travel Information
Compare train, bus, and flight for Tampa, FL to Spartanburg, SC
Omio recommends booking the flight as it is the most popular option from Tampa, FL to Spartanburg, SC among Omio's users. If you are prioritising price take the bus with prices starting from $127. For those with little time consider booking a flight which can get you there in 1h 29m. The ticket price range depends on the travel mode: a bus costs an average of $127, and a train costs an average of $202.
Distance: 484 miles (780 km)
Compare bus with
| Bus | Most popular Flight | Train | Driving |
|---|---|---|---|
$175 Average price Cheapest | $195 Average price | $231 Average price | $115 Average price (fuel + tolls) |
20h 29m Average total duration 19h 59m Onboard + 30m Additional time* | 4h 29m Average total duration Fastest 1h 29m Onboard + 3h 0m Additional time* | 36h 2m Average total duration 35h 32m Onboard + 30m Additional time* | 8h 37m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Tampa, FL to Spartanburg, SC:
A bus is $20 (€16) less than a flight for this route with tickets for a flight from Tampa, FL to Spartanburg, SC costing on average $195 (€159).
A bus is $56 (€46) less than a train for this route with tickets for a train from Tampa, FL to Spartanburg, SC costing on average $231 (€189).
Other travel options to Spartanburg, SC take longer:
Bus takes on average 19h 59m.
Train takes on average 35h 32m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
Tampa, FL to Spartanburg, SC Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 02:35AM | Arrival Time 11:45PM | Duration 21h10 | Departure days Wed, Thu | Cheapest price $127 |
Operator FlixBus | Departure Time 03:35AM | Arrival Time 12:45AM | Duration 21h10 | Departure days Thu | Cheapest price $171 |
Operator FlixBus | Departure Time 06:50AM | Arrival Time 06:15AM | Duration 23h25 | Departure days Thu | Cheapest price $117 |
Operator Greyhound | Departure Time 11:10AM | Arrival Time 10:15AM | Duration 23h05 | Departure days Thu | Cheapest price $116 |
Operator Greyhound | Departure Time 03:10PM | Arrival Time 07:35AM | Duration 16h25 | Departure days Wed | Cheapest price $162 |
Operator Greyhound | Departure Time 10:10PM | Arrival Time 06:15AM | Duration 32h05 | Departure days Thu | Cheapest price $117 |
Operator Greyhound | Departure Time 10:35PM | Arrival Time 06:15AM | Duration 31h40 | Departure days Thu | Cheapest price $117 |
Compare prices and tickets Tampa, FL to Spartanburg, SC by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Bus from Tampa, FL to Spartanburg, SC
Buses from Tampa, FL to Spartanburg, SC run on average 5 times per day, taking around 19h 59m. Cheap bus tickets for this journey start at $127 (€104) but you can travel from only $93 (€76) by flight.
The earliest bus runs at 04:04, the last at 22:35. The fastest bus covers the 484 miles (780 km) distance in 16h 25m.
Distance 484 miles (780 km) |
Average bus duration 19h 59m |
Cheapest ticket price $127 (€104) |
Buses per day 5 |
Fastest bus 16h 25m |
First bus 4:04 AM |
Last bus 10:35 PM |
Cheapest Month Sep |
Cheapest Day Mon |
High Season Jan - Mar |
Low Season Jul - Sep |
FAQs: Bus from Tampa, FL to Spartanburg, SC
Find answers to the most common questions about traveling from Tampa, FL to Spartanburg, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Spartanburg, SC, this guide helps you travel smarter and with confidence.

Most popular bus connections from Tampa, FL
More options for your journey from Tampa, FL to Spartanburg, SC
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