- Recommended
Spartanburg Science Center
Science and history museum with regional exhibits, a planetarium, and family-friendly programs in downtown Spartanburg.
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Travel Information
Compare train, bus, and flight for Tampa, FL to Spartanburg, SC
Omio recommends booking the flight as it is the most popular option from Tampa, FL to Spartanburg, SC among Omio's users. If you are prioritising price, take the bus, with an average ticket price of €149 For those with little time, consider booking a flight, which has an average total journey time of 5h 14m. Average ticket prices depend on the travel mode: a bus costs an average of €149, while a flight costs an average of €401.
Distance: 484 miles (780 km)
Compare bus with
| Bus | Most popular Flight | Train | Driving |
|---|---|---|---|
€149 Average price Cheapest | €401 Average price | €199 Average price | €96 Average price (fuel + tolls) |
16h 20m Average total duration 15h 50m Onboard + 30m Additional time* | 5h 14m Average total duration Fastest 3h 14m Onboard + 2h 0m Additional time* | 22h 24m Average total duration 21h 54m Onboard + 30m Additional time* | 8h 37m Average total duration (door-to-door) |
 Most popular bus company |  Most popular airline |  Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
The cheapest way to travel from Tampa, FL to Spartanburg, SC is a bus with an average price of €149.
This is compared to other travel options from Tampa, FL to Spartanburg, SC:
A bus is €50 less than a train for this route with tickets for a train from Tampa, FL to Spartanburg, SC costing on average €199.
A bus is €252 less than a flight for this route with tickets for a flight from Tampa, FL to Spartanburg, SC costing on average €401.
The fastest way to travel from Tampa, FL to Spartanburg, SC is by flight with an average journey time of 3h 14m.
Other travel options to Spartanburg, SC take longer:
Bus takes on average 15h 50m.
Train takes on average 21h 54m.
It's helpful to compare your options as there are 3 ways to travel between Tampa, FL and Spartanburg, SC including taking a train, bus, and flight.
We recommend using the flight as it is the most popular way to get from Tampa, FL to Spartanburg, SC among Omio's users.
Take the bus. It's the cheapest way to make this trip, and the price gap is usually bigger than people expect.
Tickets start at around €149 compared to roughly €96 in fuel and tolls — a saving of about €-53.26. The journey takes 15h 50m versus 8h 37m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
Tampa, FL to Spartanburg, SC Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 02:35AM | Arrival Time 11:45PM | Duration 21h10 | Departure days Wed, Thu, Fri | Cheapest price €104 |
Operator FlixBus | Departure Time 03:35AM | Arrival Time 12:45AM | Duration 21h10 | Departure days Thu, Fri | Cheapest price €140 |
Operator Greyhound | Departure Time 03:10PM | Arrival Time 07:35AM | Duration 16h25 | Departure days Wed, Thu | Cheapest price €133 |
Compare prices and tickets Tampa, FL to Spartanburg, SC by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Bus from Tampa, FL to Spartanburg, SC
USAUSA
Buses from Tampa, FL to Spartanburg, SC run on average 4 times per day, taking around 15h 50m. Cheap bus tickets for this journey start at €80 but you can travel from only €43 by flight.
The earliest bus runs at 04:04, the last at 22:35. The fastest bus covers the 484 miles (780 km) distance in 14h 15m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from €43
Distance 484 miles (780 km) |
Average bus duration 15h 50m |
Cheapest ticket price €80 |
Buses per day 4 |
Fastest bus 14h 15m |
First bus 4:04 AM |
Last bus 10:35 PM |
Cheapest Month Sep |
Cheapest Day Sun |
High Season Jan - Mar |
Low Season Jul - Sep |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from €43
Complete guide to Spartanburg, SC
Things to do in Spartanburg, SC
Discover the best of Spartanburg, SC — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Spartanburg, SC trip today.
- Recommended
Spartanburg Art Museum
Art museum and gallery space on the Chapman Cultural Center campus, featuring rotating exhibitions and local artists.
- Recommended
Hub City Railroad Museum
Rail museum with historic locomotives, cars, and exhibits on regional railroad history near downtown Spartanburg.
- Must visit
Morgan Square
Central downtown square with shops, public art, seating, and frequent events; a practical starting point for exploring Spartanburg.
- Recommended
Mary Black Rail Trail
Popular urban greenway for walking and cycling, linking downtown with parks, public art, and neighborhood views.
- Recommended
Croft State Park
Large city park with trails, sports areas, gardens, and open space for a relaxed outdoor break close to downtown.
FAQs: Bus from Tampa, FL to Spartanburg, SC
Find answers to the most common questions about traveling from Tampa, FL to Spartanburg, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Spartanburg, SC, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Tampa, FL to Spartanburg, SC can start from as little as €80 when you book in advance. The average bus ticket price for Tampa, FL to Spartanburg, SC is €149 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Tampa, FL to Spartanburg, SC is 14h 15m to travel the 484 miles (780 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Tampa, FL to Spartanburg, SC leaves at 4:04 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Tampa, FL to Spartanburg, SC leaves at 10:35 PM.
A trip to Spartanburg, SC from Tampa, FL is worth doing but not as a day trip with a journey time of 14h 15m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Tampa, FL to Spartanburg, SC is September.
It's helpful to compare your options as there are 3 ways to travel between Tampa, FL and Spartanburg, SC including taking a train, bus, and flight.
No, the bus from Tampa, FL to Spartanburg, SC has no accessibility options.
No, there are no bathrooms on board the bus from Tampa, FL to Spartanburg, SC.
No, bikes are not allowed on board the bus from Tampa, FL to Spartanburg, SC.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
No, there is no food available to purchase on board the bus from Tampa, FL to Spartanburg, SC.
No, luggage for the bus from Tampa, FL to Spartanburg, SC needs to be booked in addition.
No, there are no additional luggage options for the bus from Tampa, FL to Spartanburg, SC.
Unfortunately, pets are not allowed on the bus from Tampa, FL to Spartanburg, SC.
No, there are no USB plugs on board the bus from Tampa, FL to Spartanburg, SC.
No, there is no WiFi on board the bus from Tampa, FL to Spartanburg, SC.
Since neither Tampa, FL nor Spartanburg, SC are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the flight as it is the most popular way to get from Tampa, FL to Spartanburg, SC among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Spartanburg, SC, travelers should stay aware of common safety concerns such as petty theft and occasional vehicle break-ins, especially in parking areas near popular attractions. It’s advisable to avoid poorly lit or unfamiliar neighborhoods at night. Scams are not widespread but travelers should be cautious about unsolicited offers for transportation or tours, and only use licensed services to avoid overcharging or fraud. Staying alert and securing personal belongings can help ensure a safe visit.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Tampa, FL to Spartanburg, SC
Most Tampa, FL to Spartanburg, SC buses use the Tampa, Marion Transit Center to station pair. Use this guide to compare Tampa, FL and Spartanburg, SC bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in Tampa
Arrival bus stations in Spartanburg
Which Tampa, FL station do buses to Spartanburg, SC leave from?
Buses from Tampa, FL to Spartanburg, SC leave from Tampa, Marion Transit Center. The station is 0 miles (1 km) from Tampa, FL city centre at Marion Transit Center, 1211 N Marion St, Tampa, FL 33602, USA.
Tampa, Marion Transit CenterMarion Transit Center, 1211 N Marion St, Tampa, FL 33602, USA
City-centre transport
Getting to Tampa, Marion Transit Center from Tampa city centre
Bus1, 5, 19, 30 · 3m · €4 · every ~15 min
Tampa, Marion Transit Center bus station facilities and services
Tampa, Marion Transit Center has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Tampa, Marion Transit Center. ATMs are available at Tampa, Marion Transit Center.
Tickets and information
Ticket office support is available at Tampa, Marion Transit Center.
Parking, taxis and toilets
Available at Tampa, Marion Transit Center: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Tampa, Marion Transit Center: Wheelchair accessible with ramps.
Tampa, USF Holly Drive (Central Plant)University of South Florida, Central Plant, 13302 USF Chestnut Dr, Tampa, FL 33620, USA
City-centre transport
Getting to Tampa, USF Holly Drive (Central Plant) from Tampa city centre
Tampa, USF Holly Drive (Central Plant) is 13 km from Tampa city centre. Public transport options include:
BusFlixBus 2421 · 26m · €1
9, 400 · 1h 3m · €4 · every ~7 min
6 · 1h 9m · €4 · every ~5 min
Tampa, USF Holly Drive (Central Plant) bus station facilities and services
Tampa, USF Holly Drive (Central Plant) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Tampa, USF Holly Drive (Central Plant). ATMs are available at Tampa, USF Holly Drive (Central Plant).
Tickets and information
Ticket office support is available at Tampa, USF Holly Drive (Central Plant).
Parking, taxis and toilets
Available at Tampa, USF Holly Drive (Central Plant): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Tampa, USF Holly Drive (Central Plant): Wheelchair accessible facilities.
Most popular bus connections from Tampa, FL
More options for your journey from Tampa, FL to Spartanburg, SC
Here are some other resources that might have the information you need
Most popular buses to and from Spartanburg, SC and Tampa, FL
Most popular bus connections to Spartanburg, SC
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