Orlando, FL to Spartanburg, SC bus

Sun, Feb 01
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FlixBus
Costa Verde
Alsa
BlaBlaCar Bus
Rede Expressos
1,000+ travel companies
FlixBus
Costa Verde
Alsa
BlaBlaCar Bus
Rede Expressos
1,000+ travel companies
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Compare prices and tickets Orlando, FL to Spartanburg, SC by train

Compare train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

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Journey information

Overview: Bus from Orlando, FL to Spartanburg, SC

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Take a bus from Orlando, FL to Spartanburg, SC and enjoy the approximately 444 miles (715 km) long journey. Find schedules and pricing options for a convenient and affordable trip.

The earliest bus runs at 05:15, the last at 22:40.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Train from $388 (€307)
Distance
444 miles (715 km)
Buses per day
5
First bus
05:15
Last bus
22:40
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Train from $388 (€307)

FAQs: Bus from Orlando, FL to Spartanburg, SC

Find answers to the most common questions about traveling from Orlando, FL to Spartanburg, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Spartanburg, SC, this guide helps you travel smarter and with confidence.

FAQs
The earliest bus from Orlando, FL to Spartanburg, SC leaves at 5:15 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Orlando, FL to Spartanburg, SC leaves at 10:40 PM.
The cheapest month for a bus from Orlando, FL to Spartanburg, SC is January.
Yes, you can take a train between Orlando, FL and Spartanburg, SC.
No, the bus from Orlando, FL to Spartanburg, SC has no accessibility options.
No, there are no bathrooms on board the bus from Orlando, FL to Spartanburg, SC.
No, bikes are not allowed on board the bus from Orlando, FL to Spartanburg, SC.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
No, there is no food available to purchase on board the bus from Orlando, FL to Spartanburg, SC.
No, luggage for the bus from Orlando, FL to Spartanburg, SC needs to be booked in addition.
No, there are no additional luggage options for the bus from Orlando, FL to Spartanburg, SC.
Unfortunately, pets are not allowed on the bus from Orlando, FL to Spartanburg, SC.
No, there are no USB plugs on board the bus from Orlando, FL to Spartanburg, SC.
No, there is no WiFi on board the bus from Orlando, FL to Spartanburg, SC.

popular bus stations

Popular bus stations from Orlando, FL to Spartanburg, SC

Orlando
Spartanburg
The major bus station for departures in Orlando is Orlando, N John Young Pkwy (Greyhound Bus Station). Find all the information you need to know about services, amenities and connections at Orlando, N John Young Pkwy (Greyhound Bus Station) for your trip from Orlando to Spartanburg.
Orlando, N John Young Pkwy (Greyhound Bus Station)
information
Orlando, The Florida Mall
information
address
Address
Orlando Florida Mall Ave,Florida Mall Ave 1632,32809

More options for your journey from Orlando, FL to Spartanburg, SC

Here are some other resources that might have the information you need

Return journeys for buses from Spartanburg, SC to Orlando, FL
Tickets and more information for coaches to Orlando, FL

Most popular buses to and from Spartanburg, SC and Orlando, FL

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Bus Orlando, FL - Newark, NJ
Bus Orlando, FL - Denver, CO
Bus Orlando, FL - New Orleans, LA
Bus New York, NY - Spartanburg, SC
Bus Chicago, IL - Spartanburg, SC
Bus Washington, DC - Spartanburg, SC
Bus Atlanta, GA - Spartanburg, SC
Bus Las Vegas, NV - Spartanburg, SC
Bus Sacramento, CA - Spartanburg, SC
Bus Tampa, FL - Spartanburg, SC
Bus Baltimore, MD - Spartanburg, SC
Bus San Antonio, TX - Spartanburg, SC
Bus Milwaukee, WI - Spartanburg, SC
Bus Charlotte, NC - Spartanburg, SC
Bus Memphis, TN - Spartanburg, SC
Bus Harrisburg, PA - Spartanburg, SC
Bus Savannah, GA - Spartanburg, SC
Bus Fayetteville, NC - Spartanburg, SC
Bus Rensselaer, NY - Spartanburg, SC
Bus Greenville, SC - Spartanburg, SC
Bus Durham, NC - Spartanburg, SC
Bus Charleston, WV - Spartanburg, SC
Bus Charleston, SC - Spartanburg, SC
Bus Gainesville, GA - Spartanburg, SC
Bus Brattleboro, VT - Spartanburg, SC

Most popular bus connections to Spartanburg, SC

Bus Atlanta, GA - Spartanburg, SC
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