- Must visit
Virginia Museum of Transportation
Hands-on transportation museum focused on Roanoke's rail history, with locomotives, model trains, and exhibits inside a former freight station.
Cheapest price on Oct 12
$143
Average ticket price on Oct 12
$185
Fastest journey on Oct 12
15 h 30 m
Average journey duration on Oct 12
17 h
Buses on Oct 12
2
Distance
426 km
The best way to find a cheap bus ticket from Harrisburg, PA to Roanoke, VA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Harrisburg, PA to Roanoke, VA will cost around $185 if you buy it on the day, but the cheapest tickets can be found for only $143.
It's difficult to get from Harrisburg, PA to Roanoke, VA without transferring at least once.
FlixBus+
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FlixBus · FlixBus
FlixBus · FlixBus
FlixBus+
· Buses from Harrisburg, PA to Roanoke, VA run on average 1 times per day, taking around 12h 29m. Cheap bus tickets for this journey start at $84 (€70) if you book in advance.
The earliest bus runs at 04:25, the last at 17:30. The fastest bus covers the 264 miles (426 km) distance in 11h 45m.
Distance 264 miles (426 km) |
Average bus duration 12h 29m |
Cheapest ticket price $84 (€70) |
Buses per day 1 |
Fastest bus 11h 45m |
First bus 4:25 AM |
Last bus 5:30 PM |
Cheapest Month Aug |
Cheapest Day Sun |
High Season Jul - Sep |
Low Season Oct - Dec |
Best time to book 35 days |
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 01:40AM | Arrival Time 05:10PM | Duration 15h30 | Departure days Mon, Sun | Cheapest price $212 |
Operator FlixBus | Departure Time 12:25PM | Arrival Time 10:55AM | Duration 22h30 | Departure days Sun | Cheapest price $235 |
Operator Greyhound USA | Departure Time 12:30PM | Arrival Time 12:05PM | Duration 23h35 | Departure days Tue, Thu, Sat | Cheapest price $93 |
Operator Greyhound | Departure Time 05:30PM | Arrival Time 11:59AM | Duration 18h29 | Departure days Mon, Sun | Cheapest price $143 |
Operator Greyhound | Departure Time 06:50PM | Arrival Time 04:05PM | Duration 21h15 | Departure days Wed | Cheapest price $205 |
Operator Greyhound | Departure Time 07:50PM | Arrival Time 05:05PM | Duration 21h15 | Departure days Fri | Cheapest price $87 |
Operator FlixBus | Departure Time 09:10PM | Arrival Time 05:10PM | Duration 20h00 | Departure days Sun | Cheapest price $187 |
The table below shows live departures for Harrisburg, PA to Roanoke, VA buses for today, Sunday, October 11. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus+ · | 5:30 PM Harrisburg, Market St (Bus Station), PA | 18h29 | 11:59 AM Roanoke, Third Street Station, VA | 2 transfers | |
FlixBus+ · | 9:10 PM Harrisburg, Market St (Bus Station), PA | 20h00 | 5:10 PM Roanoke, VA | 2 transfers | |
| Monday, October 12 | |||||
FlixBus · FlixBus | 1:40 AM Harrisburg, Market St (Bus Station), PA | 15h30 | 5:10 PM Roanoke, VA | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Discover the best of Roanoke, VA — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Roanoke, VA trip today.
Hands-on transportation museum focused on Roanoke's rail history, with locomotives, model trains, and exhibits inside a former freight station.
Contemporary and historic art museum in a striking modern building downtown. Its galleries and sculpture spaces make it a leading cultural stop.
Regional history museum covering southwest Virginia through artifacts, photographs, and changing exhibits in downtown Roanoke.
Downtown open-air market district with historic buildings, local shops, and frequent events. It is the city's liveliest area for walking and people-watching.
Mountain park with scenic overlooks, trails, and access to the Roanoke Star. A top outdoor area for views, short hikes, and sunset visits.
Urban greenway following the Roanoke River through parks and downtown. It is ideal for walking, cycling, and seeing the city at a relaxed pace.
Slow-cured Virginia country ham is saltier and drier than typical ham, often served in biscuits. It reflects the curing traditions of Virginia smokehouses.
Brunswick stew is a regional Virginia staple made with slow-cooked chicken or pork, tomatoes, beans, and corn. It is a classic comfort food in western Virginia.
Fried apples are a Southern side of tart apples cooked with butter and spices until tender. They are common in Virginia home cooking and mountain restaurants.
Long-running neighborhood spot serving Texas-style barbecue, smoked meats, and classic Southern sides in a casual setting.
Popular downtown brewery and restaurant with house beers, hearty pub food, and a lively warehouse-style space near the market district.
Stylish farm-to-table restaurant in downtown Roanoke known for seasonal Southern dishes, craft cocktails, and an energetic modern atmosphere.
Moderate by U.S. standards. Hotels and dining are usually cheaper than major cities, while car travel is common and public transit is limited for tourists.
Tip 18-20% at restaurants, 10-15% for taxis, and $1-2 per drink or coffee in cafes if service is good.
Find answers to the most common questions about traveling from Harrisburg, PA to Roanoke, VA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Roanoke, VA, this guide helps you travel smarter and with confidence.

Most Harrisburg, PA to Roanoke, VA buses use the Harrisburg, Market St (Bus Station) to Roanoke, Third Street Station station pair. Use this guide to compare Harrisburg, PA and Roanoke, VA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Harrisburg, Market St (Bus Station) is 1 km from Harrisburg city centre. Public transport options include:
Harrisburg, Market St (Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Free WiFi inside the station. ATMs are available at Harrisburg, Market St (Bus Station).
Ticket office support is available at Harrisburg, Market St (Bus Station).
Available at Harrisburg, Market St (Bus Station): Parking, Taxis, WC.
Accessibility facilities are available at Harrisburg, Market St (Bus Station): Wheelchair accessible with ramps.
Roanoke, Third Street Station has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Roanoke, Third Street Station. ATMs are available at Roanoke, Third Street Station.
Ticket office support is available at Roanoke, Third Street Station.
Available at Roanoke, Third Street Station: Parking, Taxis, WC.
Accessibility facilities are available at Roanoke, Third Street Station: Station is wheelchair accessible.
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