- Must visit
Taubman Museum of Art
A leading art museum in Downtown Roanoke known for its striking contemporary architecture and rotating exhibitions spanning American art, regional works, and modern pieces.
Cheapest price
$213
Average price
$213
Fastest journey
21 h 15 m
Average duration
21 h 15 m
Buses per day
1
Distance
426 km
The best way to find a cheap bus ticket from Harrisburg, PA to Roanoke, VA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Harrisburg, PA to Roanoke, VA will cost around $213 if you buy it on the day, but the cheapest tickets can be found for only $213.
Of the 1 buses that leave Harrisburg, PA for Roanoke, VA on Wed, May 27, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Wed, May 27 the direct buses cover the 426 km distance in an average of 21 h 15 m but if you time it right, some buses will get you there in just 21 h 15 m .
On Wed, May 27 the slowest buses will take 21 h 15 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Omio recommends booking the bus as it is the most popular option from Harrisburg, PA to Roanoke, VA among Omio's users. If you are prioritising price take the bus with prices starting from $90. For those with little time consider booking a flight which can get you there in 5h 9m. The ticket price range depends on the travel mode: a bus costs an average of $90, and a flight costs an average of $248.
Distance: 264 miles (426 km)
Most popular Bus | Train | Flight | Driving |
|---|---|---|---|
$158 Average price Cheapest | $186 Average price | $389 Average price | $59 Average price (fuel + tolls) |
21h 45m Average total duration 21h 15m Onboard + 30m Additional time* | 11h 58m Average total duration 11h 28m Onboard + 30m Additional time* | 8h 9m Average total duration Fastest 5h 9m Onboard + 3h 0m Additional time* | 4h 22m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Harrisburg, PA to Roanoke, VA:
A bus is $28 (€23) less than a train for this route with tickets for a train from Harrisburg, PA to Roanoke, VA costing on average $186 (€150).
A bus is $231 (€186) less than a flight for this route with tickets for a flight from Harrisburg, PA to Roanoke, VA costing on average $389 (€314).
Other travel options to Roanoke, VA take longer:
Train takes on average 11h 28m.
Bus takes on average 21h 15m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound USA | Departure Time 12:30PM | Arrival Time 12:05PM | Duration 23h35 | Departure days Tue, Thu, Sat, Sun | Cheapest price $97 |
Operator Greyhound | Departure Time 06:50PM | Arrival Time 04:05PM | Duration 21h15 | Departure days Mon, Wed | Cheapest price $171 |
Operator Greyhound | Departure Time 07:50PM | Arrival Time 05:05PM | Duration 21h15 | Departure days Fri | Cheapest price $90 |
The table below shows live departures for Harrisburg, PA to Roanoke, VA buses for tomorrow, Wednesday, May 27. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 6:50 PM Harrisburg, PA | 21h15 | 4:05 PM Roanoke, VA | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Harrisburg, PA to Roanoke, VA run on average 1 times per day, taking around 21h 15m. Cheap bus tickets for this journey start at $90 (€73) if you book in advance.
The earliest bus runs at 04:25, the last at 17:30. The fastest bus covers the 264 miles (426 km) distance in 21h 15m.
Distance 264 miles (426 km) |
Average bus duration 21h 15m |
Cheapest ticket price $90 (€73) |
Buses per day 1 |
Fastest bus 21h 15m |
First bus 4:25 AM |
Last bus 5:30 PM |
Cheapest Month Feb |
Cheapest Day Fri |
High Season Jan - Mar |
Low Season Apr - Jun |
Best time to book 70 days |
Discover the best of Roanoke — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Roanoke trip today.
A leading art museum in Downtown Roanoke known for its striking contemporary architecture and rotating exhibitions spanning American art, regional works, and modern pieces.
Roanoke’s signature museum for rail and transport history, featuring locomotives, rail cars, automobiles, and aviation exhibits tied closely to the city’s railroad heritage.
A specialized museum dedicated to the iconic night photography of railroad artist O. Winston Link, housed in Roanoke’s historic passenger station.
A large mountain park with overlooks, trails, and access to the Roanoke Star, making it one of the city’s best outdoor destinations.
The city’s main visitor hub, combining historic streets, murals, markets, museums, and a lively but walkable urban atmosphere.
Scenic mountain viewpoints just outside the city offering classic Blue Ridge vistas, especially popular for photography and sunset stops.
Small biscuits filled with salty cured Virginia ham, a classic snack across Virginia and common at gatherings and brunches.
A Southern spread made with cheese, pimentos, and mayonnaise, often served with crackers or in sandwiches and popular in Virginia.
A comforting Appalachian and Southern staple of stewed chicken with soft dumplings, widely loved in the Roanoke Valley.
A well-known neighborhood restaurant serving refined Southern food with seasonal ingredients in a relaxed but polished setting.
An established farm-to-table restaurant in nearby Grandin Village known for regional ingredients, craft drinks, and an upscale atmosphere.
A historic Roanoke diner famous for chili, hot dogs, and late-night comfort food in a tiny, old-school setting.
Costs are moderate by U.S. standards. Meals and coffee are fairly priced, while upscale dining and downtown hotels cost more.
Tip 18-20% at restaurants; 15-20% for taxis and rideshares. Tip USD 1-2 per drink at bars, USD 2-5 per night for hotel housekeeping, and round up for casual service.
Find answers to the most common questions about traveling from Harrisburg, PA to Roanoke, VA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Roanoke, VA, this guide helps you travel smarter and with confidence.

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