- Must visit
Taubman Museum of Art
Major downtown art museum with rotating exhibitions and a striking contemporary building; the city’s leading visual arts venue.
Cheapest price
$106
Average price
$106
Fastest journey
18 h 35 m
Average duration
18 h 35 m
Buses per day
1
Distance
426 km
The best way to find a cheap bus ticket from Harrisburg, PA to Roanoke, VA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Harrisburg, PA to Roanoke, VA will cost around $106 if you buy it on the day, but the cheapest tickets can be found for only $106.
It's difficult to get from Harrisburg, PA to Roanoke, VA without transferring at least 2 times.
FlixBus+
·
FlixBus+
· Omio recommends booking the train as it is the most popular option from Harrisburg, PA to Roanoke, VA among Omio's users. If you are prioritising price take the bus with prices starting from $88. For those with little time consider booking a flight which can get you there in 5h 9m. The ticket price range depends on the travel mode: a bus costs an average of $88, and a flight costs an average of $243.
Distance: 264 miles (426 km)
| Bus | Most popular Train | Flight | Driving |
|---|---|---|---|
$155 Average price Cheapest | $183 Average price | $382 Average price | $58 Average price (fuel + tolls) |
21h 45m Average total duration 21h 15m Onboard + 30m Additional time* | 11h 58m Average total duration 11h 28m Onboard + 30m Additional time* | 8h 9m Average total duration Fastest 5h 9m Onboard + 3h 0m Additional time* | 4h 22m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Harrisburg, PA to Roanoke, VA:
A bus is $27 (€23) less than a train for this route with tickets for a train from Harrisburg, PA to Roanoke, VA costing on average $183 (€150).
A bus is $226 (€186) less than a flight for this route with tickets for a flight from Harrisburg, PA to Roanoke, VA costing on average $382 (€314).
Other travel options to Roanoke, VA take longer:
Train takes on average 11h 28m.
Bus takes on average 21h 15m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound USA | Departure Time 12:30PM | Arrival Time 12:05PM | Duration 23h35 | Departure days Thu | Cheapest price $95 |
Operator Greyhound | Departure Time 05:30PM | Arrival Time 12:05PM | Duration 18h35 | Departure days Mon, Tue, Wed, Sat, Sun | Cheapest price $97 |
Operator Greyhound | Departure Time 07:50PM | Arrival Time 05:05PM | Duration 21h15 | Departure days Fri | Cheapest price $88 |
The table below shows live departures for Harrisburg, PA to Roanoke, VA buses for today, Saturday, July 11. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus+ · | 5:30 PM Harrisburg, Market St (Bus Station), PA | 18h35 | 12:05 PM Roanoke, Third Street Station, VA | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Harrisburg, PA to Roanoke, VA run on average 1 times per day, taking around 21h 15m. Cheap bus tickets for this journey start at $88 (€73) if you book in advance.
The earliest bus runs at 04:25, the last at 17:30. The fastest bus covers the 264 miles (426 km) distance in 21h 15m.
Distance 264 miles (426 km) |
Average bus duration 21h 15m |
Cheapest ticket price $88 (€73) |
Buses per day 1 |
Fastest bus 21h 15m |
First bus 4:25 AM |
Last bus 5:30 PM |
Cheapest Month Feb |
Cheapest Day Fri |
High Season Jan - Mar |
Low Season Apr - Jun |
Best time to book 70 days |
Discover the best of Roanoke — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Roanoke trip today.
Major downtown art museum with rotating exhibitions and a striking contemporary building; the city’s leading visual arts venue.
Well-known rail and transportation museum featuring locomotives, rail history, automobiles, and aviation exhibits.
Specialized museum dedicated to the famed railroad photographer, with memorable Norfolk and Western night photographs and local rail history.
Large mountain park with scenic drives, overlooks, trails, and access to the famous star; one of the city’s top outdoor areas.
Walkable city center with historic buildings, public art, museums, and event spaces; the main area for first-time visitors.
Scenic viewpoints along the parkway near the city, especially popular for mountain views, foliage, and photography.
Salt-cured, aged ham that is a classic Virginia specialty, often served in biscuits or with red-eye gravy.
A Southern breakfast staple common in Southwest Virginia, featuring flaky biscuits topped with rich sausage gravy.
A beloved Southern spread made with cheese, pimentos, and mayonnaise, often served with crackers or in sandwiches.
A well-regarded neighborhood restaurant known for refined Southern cooking, craft cocktails, and a polished but relaxed atmosphere.
A popular Roanoke spot serving creative small plates, cocktails, and brunch in a stylish, lively setting.
An iconic long-running diner famous for chili dogs, burgers, and classic late-night counter service with local character.
Roanoke is generally moderate for U.S. travelers, with fairly affordable meals and coffee, while upscale dining costs more.
Tip 18-20% at restaurants; 15-20% is common for good service. Tip bartenders USD 1-2 per drink, taxis about 10-15%, and round up for casual service.
Find answers to the most common questions about traveling from Harrisburg, PA to Roanoke, VA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Roanoke, VA, this guide helps you travel smarter and with confidence.

Here are some other resources that might have the information you need