- Must visit
Virginia Museum of Transportation
Hands-on transportation museum focused on Roanoke's rail history, with locomotives, model trains, and exhibits inside a former freight station.
The best way to find a cheap bus ticket from Orlando, FL to Roanoke, VA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Orlando, FL to Roanoke, VA will cost around $134 if you buy it on the day, but the cheapest tickets can be found for only $113.
It's difficult to get from Orlando, FL to Roanoke, VA without transferring at least once.
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| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 11:30AM | Arrival Time 11:59AM | Duration 24h29 | Departure days Mon, Sun | Cheapest price $175 |
Operator FlixBus | Departure Time 02:00PM | Arrival Time 11:59AM | Duration 45h59 | Departure days Mon, Tue, Wed | Cheapest price $98 |
Operator Greyhound | Departure Time 10:55PM | Arrival Time 03:40AM | Duration 28h45 | Departure days Mon, Tue, Wed, Sun | Cheapest price $97 |
The table below shows live departures for Orlando, FL to Roanoke, VA buses for today, Sunday, November 8. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus+![]() | 10:55 PM Orlando, N John Young Pkwy (Greyhound Bus Station) | 28h45 | 3:40 AM Roanoke, Third Street Station, VA | 2 transfers | |
| Monday, November 9 | |||||
FlixBus+![]() | 11:30 AM Orlando, N John Young Pkwy (Greyhound Bus Station) | 24h29 | 11:59 AM Roanoke, Third Street Station, VA | 1 transfer | |
FlixBus+ · · | 2:00 PM Orlando, The Florida Mall, FL | 45h59 | 11:59 AM Roanoke, Third Street Station, VA | 4 transfers | |
This is the last bus of the day. | |||||
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Discover the best of Roanoke, VA — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Roanoke, VA trip today.
Hands-on transportation museum focused on Roanoke's rail history, with locomotives, model trains, and exhibits inside a former freight station.
Contemporary and historic art museum in a striking modern building downtown. Its galleries and sculpture spaces make it a leading cultural stop.
Regional history museum covering southwest Virginia through artifacts, photographs, and changing exhibits in downtown Roanoke.
Downtown open-air market district with historic buildings, local shops, and frequent events. It is the city's liveliest area for walking and people-watching.
Mountain park with scenic overlooks, trails, and access to the Roanoke Star. A top outdoor area for views, short hikes, and sunset visits.
Urban greenway following the Roanoke River through parks and downtown. It is ideal for walking, cycling, and seeing the city at a relaxed pace.
Slow-cured Virginia country ham is saltier and drier than typical ham, often served in biscuits. It reflects the curing traditions of Virginia smokehouses.
Brunswick stew is a regional Virginia staple made with slow-cooked chicken or pork, tomatoes, beans, and corn. It is a classic comfort food in western Virginia.
Fried apples are a Southern side of tart apples cooked with butter and spices until tender. They are common in Virginia home cooking and mountain restaurants.
Long-running neighborhood spot serving Texas-style barbecue, smoked meats, and classic Southern sides in a casual setting.
Popular downtown brewery and restaurant with house beers, hearty pub food, and a lively warehouse-style space near the market district.
Stylish farm-to-table restaurant in downtown Roanoke known for seasonal Southern dishes, craft cocktails, and an energetic modern atmosphere.
Moderate by U.S. standards. Hotels and dining are usually cheaper than major cities, while car travel is common and public transit is limited for tourists.
Tip 18-20% at restaurants, 10-15% for taxis, and $1-2 per drink or coffee in cafes if service is good.
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Roanoke, VA.
Find answers to the most common questions about traveling from Orlando, FL to Roanoke, VA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Roanoke, VA, this guide helps you travel smarter and with confidence.

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