- Must visit
Virginia Museum of Transportation
Hands-on transportation museum focused on Roanoke's rail history, with locomotives, model trains, and exhibits inside a former freight station.
Buses from Detroit, MI to Roanoke, VA run on average 3 times per day, taking around 21h 50m. Cheap bus tickets for this journey start at $75 (€62) if you book in advance.
The earliest bus runs at 03:35, the last at 22:05. The fastest bus covers the 386 miles (622 km) distance in 19h 5m.
Distance 386 miles (622 km) |
Average bus duration 21h 50m |
Cheapest ticket price $75 (€62) |
Buses per day 3 |
Fastest bus 19h 5m |
First bus 3:35 AM |
Last bus 10:05 PM |
Cheapest Month Sep |
Cheapest Day Mon |
High Season Jul - Sep |
Low Season Jan - Mar |
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Detroit, MI to Roanoke, VA.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 12:15AM | Arrival Time 07:50AM | Duration 31h35 | Departure days Fri, Sat, Sun | Cheapest price $143 |
Operator Greyhound | Departure Time 01:15AM | Arrival Time 07:50AM | Duration 30h35 | Departure days Mon, Sun | Cheapest price $210 |
Operator Greyhound | Departure Time 03:00AM | Arrival Time 04:05PM | Duration 37h05 | Departure days Mon | Cheapest price $154 |
Operator Greyhound | Departure Time 11:05AM | Arrival Time 11:59AM | Duration 24h54 | Departure days Mon | Cheapest price $115 |
Operator Greyhound | Departure Time 03:55PM | Arrival Time 04:05PM | Duration 24h10 | Departure days Sat | Cheapest price $141 |
Operator Greyhound | Departure Time 07:55PM | Arrival Time 03:40AM | Duration 31h45 | Departure days Mon | Cheapest price $115 |
Operator Greyhound | Departure Time 11:00PM | Arrival Time 11:59AM | Duration 36h59 | Departure days Mon | Cheapest price $115 |
The table below shows live departures for Detroit, MI to Roanoke, VA buses for today, Monday, November 2. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
· · · | 7:55 PM Detroit, Greyhound Terminal | 31h45 | 3:40 AM Roanoke, Third Street Station, VA | 3 transfers | |
· + FlixBus+![]() | 11:00 PM Detroit, Greyhound Terminal | 36h59 | 11:59 AM Roanoke, Third Street Station, VA | 3 transfers | |
This is the last bus of the day. | |||||
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Discover the best of Roanoke, VA — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Roanoke, VA trip today.
Hands-on transportation museum focused on Roanoke's rail history, with locomotives, model trains, and exhibits inside a former freight station.
Contemporary and historic art museum in a striking modern building downtown. Its galleries and sculpture spaces make it a leading cultural stop.
Regional history museum covering southwest Virginia through artifacts, photographs, and changing exhibits in downtown Roanoke.
Downtown open-air market district with historic buildings, local shops, and frequent events. It is the city's liveliest area for walking and people-watching.
Mountain park with scenic overlooks, trails, and access to the Roanoke Star. A top outdoor area for views, short hikes, and sunset visits.
Urban greenway following the Roanoke River through parks and downtown. It is ideal for walking, cycling, and seeing the city at a relaxed pace.
Slow-cured Virginia country ham is saltier and drier than typical ham, often served in biscuits. It reflects the curing traditions of Virginia smokehouses.
Brunswick stew is a regional Virginia staple made with slow-cooked chicken or pork, tomatoes, beans, and corn. It is a classic comfort food in western Virginia.
Fried apples are a Southern side of tart apples cooked with butter and spices until tender. They are common in Virginia home cooking and mountain restaurants.
Long-running neighborhood spot serving Texas-style barbecue, smoked meats, and classic Southern sides in a casual setting.
Popular downtown brewery and restaurant with house beers, hearty pub food, and a lively warehouse-style space near the market district.
Stylish farm-to-table restaurant in downtown Roanoke known for seasonal Southern dishes, craft cocktails, and an energetic modern atmosphere.
Moderate by U.S. standards. Hotels and dining are usually cheaper than major cities, while car travel is common and public transit is limited for tourists.
Tip 18-20% at restaurants, 10-15% for taxis, and $1-2 per drink or coffee in cafes if service is good.
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Roanoke, VA.
Find answers to the most common questions about traveling from Detroit, MI to Roanoke, VA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Roanoke, VA, this guide helps you travel smarter and with confidence.

Most Detroit, MI to Roanoke, VA buses use the Detroit, Greyhound Terminal to Roanoke, Third Street Station station pair. Use this guide to compare Detroit, MI and Roanoke, VA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Detroit, Greyhound Terminal is 1 km from Detroit city centre. Public transport options include:
Detroit, Greyhound Terminal has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Fast food and coffee shops available.
Free Wi-Fi available in waiting areas. ATMs are aTM located near the main entrance.
Ticket office support is available at Detroit, Greyhound Terminal.
Available at Detroit, Greyhound Terminal: Parking, Taxis, WC.
Accessibility facilities are available at Detroit, Greyhound Terminal: Wheelchair accessible facilities available.
Roanoke, Third Street Station has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Roanoke, Third Street Station. ATMs are available at Roanoke, Third Street Station.
Ticket office support is available at Roanoke, Third Street Station.
Available at Roanoke, Third Street Station: Parking, Taxis, WC.
Accessibility facilities are available at Roanoke, Third Street Station: Station is wheelchair accessible.
Check bus stations information for Detroit, MI and Roanoke, VA, including where buses depart and arrive on this route.
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