Compare prices and tickets Knoxville, TN to Roanoke, VA by bus
Compare bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Knoxville, TN to Roanoke, VA buses with Omio?
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
Journey information
Overview: Bus from Knoxville, TN to Roanoke, VA
Buses from Knoxville, TN to Roanoke, VA run on average 1 times per day, taking around 5h 40m. Cheap bus tickets for this journey start at $58 (€46) if you book in advance.
There are 1 buses per day. The earliest bus runs at 12:35, the last at 22:50. The fastest bus covers the 238 miles (384 km) distance in 5h 0m.
Distance 238 miles (384 km) |
Average bus duration 5h 40m |
Cheapest ticket price $58 (€46) |
Buses per day 1 |
Direct buses 1 |
Fastest bus 5h 0m |
First bus 12:35 PM |
Last bus 10:50 PM |
Cheapest Month Jul |
Cheapest Day Sun |
High Season Jan - Mar |
Low Season Apr - Jun |
Bus providers: Greyhound from Knoxville, TN to Roanoke, VAYou can travel by bus between Knoxville, TN to Roanoke, VA with Greyhound for as low as $58 (€46). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
FAQs: Bus from Knoxville, TN to Roanoke, VA
Find answers to the most common questions about traveling from Knoxville, TN to Roanoke, VA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Roanoke, VA, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from Knoxville, TN to Roanoke, VA
Most popular bus connections from Knoxville, TN
More options for your journey from Knoxville, TN to Roanoke, VA
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