The cheapest and fastest buses from Knoxville, TN to Roanoke, VA
Cheapest price
$66
Average price
$66
Fastest journey
5 h
Average duration
5 h
Buses per day
1
Distance
384 km
The best way to find a cheap bus ticket from Knoxville, TN to Roanoke, VA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Knoxville, TN to Roanoke, VA will cost around $66 if you buy it on the day, but the cheapest tickets can be found for only $66.
Of the 1 buses that leave Knoxville, TN for Roanoke, VA on Tue, Dec 16, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Tue, Dec 16 the direct buses cover the 384 km distance in an average of 5 h but if you time it right, some buses will get you there in just 5 h .
On Tue, Dec 16 the slowest buses will take 5 h and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Knoxville, TN to Roanoke, VA Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 10:50PM | Arrival Time 03:50AM | Duration 5h00 | Departure days Mon, Tue | Cheapest price $66 |
Live departures
Knoxville, TN to Roanoke, VA bus times
The table below shows live departures for Knoxville, TN to Roanoke, VA buses for tomorrow, Tuesday, December 16. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 3:50 AM Knoxville, Kirkwood Street, TN | 5h00 | 8:50 AM Roanoke, Third Street Station, VA | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Journey information
Overview: Bus from Knoxville, TN to Roanoke, VA
Take a bus from Knoxville, TN to Roanoke, VA and enjoy the approximately 238 miles (384 km) long journey. Find schedules and pricing options for a convenient and affordable trip.
There are 1 buses per day. The earliest bus runs at 12:35, the last at 22:50.
Distance 238 miles (384 km) |
Average bus duration 5h 40m |
Buses per day 1 |
Direct buses 1 |
First bus 12:35 |
Last bus 22:50 |
Bus providers: Greyhound from Knoxville, TN to Roanoke, VAYou can travel by bus between Knoxville, TN to Roanoke, VA with Greyhound. When you search for schedules and tickets, Omio will show you the best journey
Greyhound
FAQs: Bus from Knoxville, TN to Roanoke, VA
Find answers to the most common questions about traveling from Knoxville, TN to Roanoke, VA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Roanoke, VA, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
To find the cheapest bus tickets for your trip from Knoxville, TN to Roanoke, VA, follow these tips:
Start your search now and compare ticket prices to find the best deal!
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from Knoxville, TN to Roanoke, VA
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