The cheapest and fastest buses from Knoxville, TN to Roanoke, VA
Cheapest price
$57
Average price
$57
Fastest journey
5 h
Average duration
5 h
Buses per day
1
Distance
384 km
The best way to find a cheap bus ticket from Knoxville, TN to Roanoke, VA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Knoxville, TN to Roanoke, VA will cost around $57 if you buy it on the day, but the cheapest tickets can be found for only $57.
Of the 1 buses that leave Knoxville, TN for Roanoke, VA on Thu, Mar 19, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Thu, Mar 19 the direct buses cover the 384 km distance in an average of 5 h but if you time it right, some buses will get you there in just 5 h .
On Thu, Mar 19 the slowest buses will take 5 h and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Live departures
Knoxville, TN to Roanoke, VA bus times
The table below shows live departures for Knoxville, TN to Roanoke, VA buses for tomorrow, Tuesday, March 17. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 3:50 AM Knoxville, TN | 5h00 | 8:50 AM Roanoke, VA | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Knoxville, TN to Roanoke, VA by bus
Compare bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Mar 18
Mar 19
Mar 20
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Mar 22
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Mar 24
Why should you book Knoxville, TN to Roanoke, VA buses with Omio?
Why book with Omio vs Greyhound?
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Journey information
Overview: Bus from Knoxville, TN to Roanoke, VA
Buses from Knoxville, TN to Roanoke, VA run on average 1 times per day, taking around 5h 40m. Cheap bus tickets for this journey start at $57 (€46) if you book in advance.
There are 1 buses per day. The earliest bus runs at 12:35, the last at 22:50. The fastest bus covers the 238 miles (384 km) distance in 5h 0m.
Distance 238 miles (384 km) |
Average bus duration 5h 40m |
Cheapest ticket price $57 (€46) |
Buses per day 1 |
Direct buses 1 |
Fastest bus 5h 0m |
First bus 12:35 |
Last bus 22:50 |
Bus providers: Greyhound from Knoxville, TN to Roanoke, VAYou can travel by bus between Knoxville, TN to Roanoke, VA with Greyhound for as low as $57 (€46). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
FAQs: Bus from Knoxville, TN to Roanoke, VA
Find answers to the most common questions about traveling from Knoxville, TN to Roanoke, VA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Roanoke, VA, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from Knoxville, TN to Roanoke, VA
Most popular bus connections from Knoxville, TN
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