- Must visit
Virginia Museum of Transportation
Hands-on transportation museum focused on Roanoke's rail history, with locomotives, model trains, and exhibits inside a former freight station.
Cheapest price on Sep 19
$115
Average ticket price on Sep 19
$115
Fastest journey on Sep 19
17 h 44 m
Average journey duration on Sep 19
17 h 44 m
Buses on Sep 19
1
Distance
719 km
The best way to find a cheap bus ticket from Syracuse, NY to Roanoke, VA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Syracuse, NY to Roanoke, VA will cost around $115 if you buy it on the day, but the cheapest tickets can be found for only $115.
It's difficult to get from Syracuse, NY to Roanoke, VA without transferring at least 2 times.
FlixBus · FlixBus+
FlixBus · FlixBus+
Omio recommends booking the bus as it is the most popular option from Syracuse, NY to Roanoke, VA among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $135 For those with little time, consider booking a bus, which has an average total journey time of 16h 11m. Average ticket prices depend on the travel mode: a bus costs an average of $135, while a bus costs an average of $135.
Distance: 446 miles (719 km)
Most popular Bus | Driving |
|---|---|
$135 Average price Cheapest | $106 Average price (fuel + tolls) |
16h 11m Average total duration Fastest 15h 41m Onboard + 30m Additional time* | 8h 16m Average total duration (door-to-door) |
![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options |
Tickets start at around $135 compared to roughly $106 in fuel and tolls — a saving of about $-29.51. The journey takes 15h 41m versus 8h 16m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 06:15PM | Arrival Time 11:59AM | Duration 17h44 | Departure days Sat, Sun | Cheapest price $107 |
Operator Greyhound | Departure Time 09:15PM | Arrival Time 04:05PM | Duration 18h50 | Departure days Mon, Thu | Cheapest price $109 |
Compare bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Syracuse, NY to Roanoke, VA run on average 1 times per day, taking around 15h 41m. Cheap bus tickets for this journey start at $104 if you book in advance.
The earliest bus runs at 04:35, the last at 17:15. The fastest bus covers the 446 miles (719 km) distance in 15h 24m.
Distance 446 miles (719 km) |
Average bus duration 15h 41m |
Cheapest ticket price $104 |
Buses per day 1 |
Fastest bus 15h 24m |
First bus 4:35 AM |
Last bus 5:15 PM |
Cheapest Month Jul |
Cheapest Day Tue |
High Season Jul - Sep |
Low Season Jan - Mar |
Discover the best of Roanoke, VA — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Roanoke, VA trip today.
Hands-on transportation museum focused on Roanoke's rail history, with locomotives, model trains, and exhibits inside a former freight station.
Contemporary and historic art museum in a striking modern building downtown. Its galleries and sculpture spaces make it a leading cultural stop.
Regional history museum covering southwest Virginia through artifacts, photographs, and changing exhibits in downtown Roanoke.
Downtown open-air market district with historic buildings, local shops, and frequent events. It is the city's liveliest area for walking and people-watching.
Mountain park with scenic overlooks, trails, and access to the Roanoke Star. A top outdoor area for views, short hikes, and sunset visits.
Urban greenway following the Roanoke River through parks and downtown. It is ideal for walking, cycling, and seeing the city at a relaxed pace.
Find answers to the most common questions about traveling from Syracuse, NY to Roanoke, VA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Roanoke, VA, this guide helps you travel smarter and with confidence.

Most Syracuse, NY to Roanoke, VA buses use the Syracuse, Walsh Cir (Syracuse Bus Station) to Roanoke, Third Street Station station pair. Use this guide to compare Syracuse, NY and Roanoke, VA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Syracuse, Walsh Cir (Syracuse Bus Station) is 3 km from Syracuse city centre. Public transport options include:
Syracuse, Walsh Cir (Syracuse Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Free Wi-Fi available throughout the station. ATMs are aTMs are located near the entrance.
Ticket office support is available at Syracuse, Walsh Cir (Syracuse Bus Station).
Available at Syracuse, Walsh Cir (Syracuse Bus Station): Parking, Taxis, WC.
Accessibility facilities are available at Syracuse, Walsh Cir (Syracuse Bus Station): The station is wheelchair accessible.
Roanoke, Third Street Station has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Roanoke, Third Street Station. ATMs are available at Roanoke, Third Street Station.
Ticket office support is available at Roanoke, Third Street Station.
Available at Roanoke, Third Street Station: Parking, Taxis, WC.
Accessibility facilities are available at Roanoke, Third Street Station: Station is wheelchair accessible.
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