- Must visit
Edison and Ford Winter Estates Museum
Major local museum at the Edison and Ford estates with inventions, automobiles, and exhibits on two influential American innovators.
Cheapest price
$387
Average price
$387
Fastest journey
2 d 11 h 20 m
Average duration
2 d 11 h 20 m
Buses per day
1
Distance
1828 km
The best way to find a cheap bus ticket from Buffalo, NY to Fort Myers, FL is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Buffalo, NY to Fort Myers, FL will cost around $387 if you buy it on the day, but the cheapest tickets can be found for only $387.
Of the 1 buses that leave Buffalo, NY for Fort Myers, FL on Fri, Jul 17, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Fri, Jul 17 the direct buses cover the 1828 km distance in an average of 2 d 11 h 20 m but if you time it right, some buses will get you there in just 2 d 11 h 20 m .
On Fri, Jul 17 the slowest buses will take 2 d 11 h 20 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Omio recommends booking the train as it is the most popular option from Buffalo, NY to Fort Myers, FL among Omio's users. If you are prioritising price take the flight with prices starting from $114. For those with little time consider booking a flight which can get you there in 3h 41m. The ticket price range depends on the travel mode: a flight costs an average of $114, and a train costs an average of $305.
Distance: 1135 miles (1828 km)
| Bus | Most popular Train | Flight | Driving |
|---|---|---|---|
$295 Average price | $432 Average price | $263 Average price Cheapest | $267 Average price (fuel + tolls) |
40h 50m Average total duration 40h 20m Onboard + 30m Additional time* | 36h 44m Average total duration 36h 14m Onboard + 30m Additional time* | 6h 41m Average total duration Fastest 3h 41m Onboard + 3h 0m Additional time* | 20h 19m Average total duration (door-to-door) |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Buffalo, NY to Fort Myers, FL:
A flight is $32 (€26) less than a bus for this route with tickets for a bus from Buffalo, NY to Fort Myers, FL costing on average $295 (€242).
A flight is $168 (€138) less than a train for this route with tickets for a train from Buffalo, NY to Fort Myers, FL costing on average $432 (€354).
Other travel options to Fort Myers, FL take longer:
Train takes on average 36h 14m.
Bus takes on average 40h 20m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 02:20AM | Arrival Time 02:20PM | Duration 60h00 | Departure days Thu | Cheapest price $307 |
Operator FlixBus | Departure Time 03:20AM | Arrival Time 02:20PM | Duration 59h00 | Departure days Sun | Cheapest price $260 |
Operator Greyhound | Departure Time 03:20AM | Arrival Time 03:20PM | Duration 60h00 | Departure days Thu | Cheapest price $331 |
Operator Greyhound | Departure Time 03:59AM | Arrival Time 02:20PM | Duration 58h21 | Departure days Tue, Sat | Cheapest price $321 |
Operator FlixBus | Departure Time 04:00AM | Arrival Time 03:20PM | Duration 59h20 | Departure days Fri | Cheapest price $387 |
Operator Greyhound | Departure Time 04:59AM | Arrival Time 03:20PM | Duration 58h21 | Departure days Thu | Cheapest price $259 |
Operator Barons Bus | Departure Time 02:20PM | Arrival Time 10:20AM | Duration 68h00 | Departure days Tue | Cheapest price $319 |
Operator FlixBus | Departure Time 02:30PM | Arrival Time 02:20PM | Duration 47h50 | Departure days Wed | Cheapest price $315 |
Operator FlixBus | Departure Time 09:20PM | Arrival Time 10:20PM | Duration 49h00 | Departure days Sat | Cheapest price $143 |
The table below shows live departures for Buffalo, NY to Fort Myers, FL buses for tomorrow, Thursday, July 16. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 4:00 AM Buffalo, NY | 59h20 | 3:20 PM Fort Myers, FL | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Buffalo, NY to Fort Myers, FL run on average 5 times per day, taking around 40h 20m. Cheap bus tickets for this journey start at $143 (€117) but you can travel from only $114 (€93) by flight.
The earliest bus runs at 03:42, the last at 23:20. The fastest bus covers the 1135 miles (1828 km) distance in 47h 50m.
Distance 1135 miles (1828 km) |
Average bus duration 40h 20m |
Cheapest ticket price $143 (€117) |
Buses per day 5 |
Fastest bus 47h 50m |
First bus 3:42 AM |
Last bus 11:20 PM |
Cheapest Month Sep |
Cheapest Day Tue |
High Season Jan - Mar |
Low Season Jul - Sep |
Discover the best of Fort Myers, FL — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Fort Myers, FL trip today.
Major local museum at the Edison and Ford estates with inventions, automobiles, and exhibits on two influential American innovators.
Excellent regional history museum covering Southwest Florida's people, places, and development through engaging permanent exhibitions.
Interactive science museum with aquariums, live animals, and hands-on exhibits that make it especially strong for families and curious adults.
Walkable historic downtown filled with shops, galleries, event spaces, and river views, making it the city's main strolling district.
Large urban nature preserve with boardwalks, trails, and birding, offering a wild contrast to the built-up city center.
Palm-lined downtown street known for preserved architecture, boutiques, murals, and an easy introduction to the city's historic core.
Fresh Gulf shrimp, often peeled and eaten chilled or quickly sautéed. A Southwest Florida staple thanks to nearby shrimping waters and seafood culture.
A Florida classic of flaky local fish, usually grouper, served blackened, grilled, or fried in a sandwich. Popular along Fort Myers waterfronts.
Cracked Florida stone crab claws served chilled with mustard sauce. A prized seasonal seafood known across coastal South Florida and the Gulf.
Established fine dining restaurant serving refined seafood and steaks in an elegant historic downtown setting.
Casual waterfront seafood spot known for fresh local shrimp, grouper, and island atmosphere near the marina.
Beloved local Cuban cafe offering pressed sandwiches, coffee, pastries, and traditional Latin comfort food in a casual setting.
Moderate for Florida beach travel. Hotels and dining run mid-range, while car travel and parking add costs. Cheaper than Miami, but pricier than many inland US cities.
Tip 18-20% at restaurants, 15-20% for taxis or rideshares, and $1-2 per drink or coffee in cafes and bars.
Find answers to the most common questions about traveling from Buffalo, NY to Fort Myers, FL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Fort Myers, FL, this guide helps you travel smarter and with confidence.

Most Buffalo, NY to Fort Myers, FL buses use the Buffalo, NFTA Metro Center to Fort Myers, Rosa Parks Transit Center station pair. Use this guide to compare Buffalo, NY and Fort Myers, FL bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Here are some other resources that might have the information you need