- Must visit
Everson Museum Of Art
A major American art museum known for its ceramics collection and notable modern architecture by I. M. Pei. It is one of Syracuse’s top cultural attractions.
Cheapest price
$395
Average price
$396
Fastest journey
1 d 20 h 20 m
Average duration
1 d 20 h 50 m
Buses per day
2
Distance
1898 km
The best way to find a cheap bus ticket from Fort Myers, FL to Syracuse, NY is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Fort Myers, FL to Syracuse, NY will cost around $396 if you buy it on the day, but the cheapest tickets can be found for only $395.
It's difficult to get from Fort Myers, FL to Syracuse, NY without transferring at least 3 times.
FlixBus · FlixBus+
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FlixBus+
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FlixBus · FlixBus+
· Omio recommends booking the flight as it is the most popular option from Fort Myers, FL to Syracuse, NY among Omio's users. If you are prioritising price take the bus with prices starting from $367. For those with little time consider booking a flight which can get you there in 3h 9m. The ticket price range depends on the travel mode: a bus costs an average of $367, and a flight costs an average of $402.
Distance: 1179 miles (1898 km)
| Bus | Most popular Flight | Train | Driving |
|---|---|---|---|
$407 Average price Cheapest | $1441 Average price | $633 Average price | $275 Average price (fuel + tolls) |
38h 15m Average total duration 37h 45m Onboard + 30m Additional time* | 6h 9m Average total duration Fastest 3h 9m Onboard + 3h 0m Additional time* | 40h 21m Average total duration 39h 51m Onboard + 30m Additional time* | 20h 34m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Fort Myers, FL to Syracuse, NY:
A bus is $226 (€185) less than a train for this route with tickets for a train from Fort Myers, FL to Syracuse, NY costing on average $633 (€518).
A bus is $1033 (€845) less than a flight for this route with tickets for a flight from Fort Myers, FL to Syracuse, NY costing on average $1441 (€1179).
Other travel options to Syracuse, NY take longer:
Bus takes on average 37h 45m.
Train takes on average 39h 51m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 02:00PM | Arrival Time 11:20AM | Duration 45h20 | Departure days Sat | Cheapest price $395 |
Operator Greyhound | Departure Time 06:15PM | Arrival Time 03:20PM | Duration 45h05 | Departure days Thu | Cheapest price $367 |
Operator Flixbus USA | Departure Time 06:20PM | Arrival Time 06:55PM | Duration 48h35 | Departure days Fri | Cheapest price $361 |
Operator Greyhound | Departure Time 06:55PM | Arrival Time 03:15PM | Duration 44h20 | Departure days Sat | Cheapest price $397 |
Operator Greyhound | Departure Time 07:35PM | Arrival Time 10:05AM | Duration 38h30 | Departure days Wed | Cheapest price $390 |
Operator Greyhound | Departure Time 10:30PM | Arrival Time 05:45PM | Duration 43h15 | Departure days Tue | Cheapest price $465 |
The table below shows live departures for Fort Myers, FL to Syracuse, NY buses for tomorrow, Saturday, June 20. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus+ · | 2:00 PM Fort Myers, Rosa Parks Transit Center | 45h20 | 11:20 AM Syracuse, Walsh Cir (Syracuse Bus Station), NY | 3 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Fort Myers, FL to Syracuse, NY run on average 2 times per day, taking around 37h 45m. Cheap bus tickets for this journey start at $367 (€300) if you book in advance.
The earliest bus runs at 06:00, the last at 21:00. The fastest bus covers the 1179 miles (1898 km) distance in 38h 30m.
Distance 1179 miles (1898 km) |
Average bus duration 37h 45m |
Cheapest ticket price $367 (€300) |
Buses per day 2 |
Fastest bus 38h 30m |
First bus 6:00 AM |
Last bus 9:00 PM |
Cheapest Month Nov |
Cheapest Day Sat |
High Season Jan - Mar |
Low Season Oct - Dec |
Discover the best of Syracuse — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Syracuse trip today.
A major American art museum known for its ceramics collection and notable modern architecture by I. M. Pei. It is one of Syracuse’s top cultural attractions.
A local history museum in the last remaining weighlock building in the United States, focusing on the Erie Canal’s impact on Syracuse and New York State.
A hands-on science museum in downtown Syracuse with interactive exhibits and a planetarium, popular with families and visitors interested in STEM.
Syracuse’s best-known historic district, filled with restored warehouses, lively streets, and a strong mix of shopping, architecture, and nightlife.
A popular waterfront recreation area with trails, lake views, and sunset spots that are frequently featured in local social media posts.
A central downtown square known for historic buildings, events, and seasonal programming, including its popular winter ice rink.
Small potatoes boiled in very salty water until the skins wrinkle, then served with melted butter. They are a signature Central New York dish with roots in the region's salt industry.
A spicy pasta dish with chicken, rigatoni, peppers, and a creamy tomato sauce. Though more closely tied to nearby Utica, it is widely loved across Central New York and commonly found in Syracuse.
A bakery-style rectangular pizza served at room temperature with thick crust, tomato sauce, and little or no cheese. It is a classic Upstate New York snack and party food.
A long-running Syracuse favorite known for handmade pasta, spicy hot tomato oil, and a lively downtown atmosphere.
An established Italian restaurant on the north side, appreciated for classic pasta dishes, warm service, and a cozy neighborhood feel.
A famous casual barbecue restaurant and roadhouse-style venue known for smoked meats, classic sides, and a bustling, iconic setting.
Costs are moderate by U.S. standards. Casual dining is affordable, while hotels and fine dining cost more during peak dates.
Tip 18-20% at sit-down restaurants. Tip USD 1-2 per drink at bars, round up taxis, and tip hotel staff and delivery drivers.
Find answers to the most common questions about traveling from Fort Myers, FL to Syracuse, NY by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Syracuse, NY, this guide helps you travel smarter and with confidence.

Most Fort Myers, FL to Syracuse, NY buses use the Fort Myers, Rosa Parks Transit Center to Syracuse, Walsh Cir (Syracuse Bus Station) station pair. Use this guide to compare Fort Myers, FL and Syracuse, NY bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Here are some other resources that might have the information you need