- Must visit
Edison and Ford Winter Estates Museum
Major local museum at the Edison and Ford estates with inventions, automobiles, and exhibits on two influential American innovators.
We are not able to find a bus between these two places.
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Omio recommends booking the bus as it is the most popular option from Orlando, FL to Fort Myers, FL among Omio's users. If you are prioritising price take the bus with prices starting from $28. For those with little time consider booking a bus which can get you there in 5h 35m. The ticket price range depends on the travel mode: a bus costs an average of $28, and a flight costs an average of $431.
Distance: 135 miles (218 km)
Most popular Bus | Flight | Driving |
|---|---|---|
$47 Average price Cheapest | $470 Average price | $34 Average price (fuel + tolls) |
6h 5m Average total duration Fastest 5h 35m Onboard + 30m Additional time* | 18h 40m Average total duration 15h 40m Onboard + 3h 0m Additional time* | 3h 6m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Orlando, FL to Fort Myers, FL:
A bus is $423 (€347) less than a flight for this route with tickets for a flight from Orlando, FL to Fort Myers, FL costing on average $470 (€386).
Other travel options to Fort Myers, FL take longer:
Flight takes on average 15h 40m.
You'll arrive about -3h -29m sooner (5h 35m by bus vs 3h 6m by car) and save roughly $-13.22 (€-10.85) compared to fuel and tolls ($47 (€39) vs $34 (€28)). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by FlixBus.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 04:35AM | Arrival Time 10:20AM | Duration 5h45 | Departure days Everyday | Cheapest price $35 |
Operator FlixBus | Departure Time 05:10AM | Arrival Time 10:20AM | Duration 5h10 | Departure days Everyday | Cheapest price $35 |
Operator FlixBus | Departure Time 07:10AM | Arrival Time 12:15PM | Duration 5h05 | Departure days Mon, Tue, Fri, Sat, Sun | Cheapest price $37 |
Operator FlixBus | Departure Time 07:40AM | Arrival Time 12:15PM | Duration 4h35 | Departure days Mon, Tue, Fri, Sat, Sun | Cheapest price $37 |
Operator Amtrak | Departure Time 10:19AM | Arrival Time 04:55PM | Duration 6h36 | Departure days Mon, Thu, Sun | Cheapest price $53 |
Operator FlixBus | Departure Time 10:50AM | Arrival Time 04:35PM | Duration 5h45 | Departure days Everyday | Cheapest price $42 |
Operator FlixBus | Departure Time 12:20PM | Arrival Time 06:20PM | Duration 6h00 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price $37 |
Operator FlixBus | Departure Time 12:55PM | Arrival Time 06:20PM | Duration 5h25 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price $37 |
The table below shows live departures for Orlando, FL to Fort Myers, FL buses for tomorrow, Thursday, July 16. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus | 4:35 AM Orlando, The Florida Mall, FL | 5h45 | 10:20 AM Fort Myers, Rosa Parks Transit Center | 0 transfersDirect | |
FlixBus | 5:10 AM Orlando, N John Young Pkwy (Greyhound Bus Station) | 5h10 | 10:20 AM Fort Myers, Rosa Parks Transit Center | 0 transfersDirect | |
41 Floridian · 6091 AMTRAK | 10:19 AM Orlando Station, Orlando, FL | 6h36 | 4:55 PM Fort Myers, FL | 1 transfer | |
FlixBus | 10:50 AM Orlando, N John Young Pkwy (Greyhound Bus Station) | 5h45 | 4:35 PM Fort Myers, Rosa Parks Transit Center | 0 transfersDirect | |
FlixBus | 12:20 PM Orlando, The Florida Mall, FL | 6h00 | 6:20 PM Fort Myers, Rosa Parks Transit Center | 0 transfersDirect | |
FlixBus | 12:55 PM Orlando, N John Young Pkwy (Greyhound Bus Station) | 5h25 | 6:20 PM Fort Myers, Rosa Parks Transit Center | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Orlando, FL to Fort Myers, FL run on average 8 times per day, taking around 5h 35m. Cheap bus tickets for this journey start at $28 (€23) if you book in advance.
There are 7 buses per day. The earliest bus runs at 04:35, the last at 23:40. The fastest bus covers the 135 miles (218 km) distance in 4h 55m.
Distance 135 miles (218 km) |
Average bus duration 5h 35m |
Cheapest ticket price $28 (€23) |
Buses per day 8 |
Direct buses 7 |
Fastest bus 4h 55m |
First bus 4:35 AM |
Last bus 11:40 PM |
Cheapest Month Aug |
Cheapest Day Tue |
High Season Jan - Mar |
Low Season Jul - Sep |
Busiest Day Sat |
Least Busy Day Wed |
Best time to book 35 days |
Discover the best of Fort Myers, FL — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Fort Myers, FL trip today.
Major local museum at the Edison and Ford estates with inventions, automobiles, and exhibits on two influential American innovators.
Excellent regional history museum covering Southwest Florida's people, places, and development through engaging permanent exhibitions.
Interactive science museum with aquariums, live animals, and hands-on exhibits that make it especially strong for families and curious adults.
Walkable historic downtown filled with shops, galleries, event spaces, and river views, making it the city's main strolling district.
Large urban nature preserve with boardwalks, trails, and birding, offering a wild contrast to the built-up city center.
Palm-lined downtown street known for preserved architecture, boutiques, murals, and an easy introduction to the city's historic core.
Fresh Gulf shrimp, often peeled and eaten chilled or quickly sautéed. A Southwest Florida staple thanks to nearby shrimping waters and seafood culture.
A Florida classic of flaky local fish, usually grouper, served blackened, grilled, or fried in a sandwich. Popular along Fort Myers waterfronts.
Cracked Florida stone crab claws served chilled with mustard sauce. A prized seasonal seafood known across coastal South Florida and the Gulf.
Established fine dining restaurant serving refined seafood and steaks in an elegant historic downtown setting.
Casual waterfront seafood spot known for fresh local shrimp, grouper, and island atmosphere near the marina.
Beloved local Cuban cafe offering pressed sandwiches, coffee, pastries, and traditional Latin comfort food in a casual setting.
Moderate for Florida beach travel. Hotels and dining run mid-range, while car travel and parking add costs. Cheaper than Miami, but pricier than many inland US cities.
Tip 18-20% at restaurants, 15-20% for taxis or rideshares, and $1-2 per drink or coffee in cafes and bars.
Find answers to the most common questions about traveling from Orlando, FL to Fort Myers, FL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Fort Myers, FL, this guide helps you travel smarter and with confidence.

Most Orlando, FL to Fort Myers, FL buses use the Orlando, N John Young Pkwy (Greyhound Bus Station) to Fort Myers, Rosa Parks Transit Center station pair. Use this guide to compare Orlando, FL and Fort Myers, FL bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Here are some other resources that might have the information you need