- Must visit
Pima Air & Space Museum
World-renowned aviation museum with historic aircraft, hangars, and restoration spaces on a vast desert campus.
The best way to find a cheap bus ticket from Columbia, MO to Tucson, AZ is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Columbia, MO to Tucson, AZ will cost around $371 if you buy it on the day, but the cheapest tickets can be found for only $290.
It's difficult to get from Columbia, MO to Tucson, AZ without transferring at least 2 times.

|
| ||||||||||||

|
| ||||||||||||

|
| ||||||||||||

|
| ||||||||||||
Take a bus from Columbia, MO to Tucson, AZ and enjoy the approximately 1140 miles (1836 km) long journey. Find schedules and pricing options for a convenient and affordable trip.
The earliest bus runs at 06:00, the last at 20:35.
Plan this route
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Columbia, MO to Tucson, AZ.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound USA | Departure Time 02:40PM | Arrival Time 11:45PM | Duration 57h05 | Departure days Mon, Tue, Wed, Thu, Sun | Cheapest price $290 |
Operator Greyhound USA | Departure Time 08:05PM | Arrival Time 07:10PM | Duration 47h05 | Departure days Mon, Tue, Wed, Sun | Cheapest price $453 |
The table below shows live departures for Columbia, MO to Tucson, AZ buses for today, Monday, November 2. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 2:40 PM Columbia, MO | 57h05 | 11:45 PM Tucson, AZ | 4 transfers | |
![]() | 8:05 PM Columbia, MO | 47h05 | 7:10 PM Tucson, AZ | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Buses from Columbia, MO to Tucson, AZ with Greyhound. Use the details below to compare onboard facilities.
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
Discover the best of Tucson, AZ — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Tucson, AZ trip today.
World-renowned aviation museum with historic aircraft, hangars, and restoration spaces on a vast desert campus.
University art museum with strong Latin American, modern, and contemporary collections in a compact campus setting.
Interactive science museum for all ages with hands-on exhibits, planetarium, and rotating educational displays.
Popular mountain park with desert trails, giant cacti, and summit road views over Tucson and surrounding ranges.
Walkable historic district with adobe architecture, shops, galleries, and some of Tucson's oldest streetscapes.
Scenic desert road and trail area in Saguaro National Park West, famous for sunset drives and iconic cactus views.
A Sonoran-style hot dog wrapped in bacon and topped with beans, onions, tomato, mustard, mayo, and jalapeño sauce. A Tucson street-food icon tied to regional Mexican roots.
Carne seca is thin beef dried in the desert tradition, then often shredded and cooked with eggs or chiles. It reflects Tucson’s ranching and borderlands heritage.
A wheat tortilla folded around cheese and often grilled over mesquite. This regional staple shows Tucson’s long flour-tortilla tradition rooted in Sonoran cuisine.
Upscale destination for creative desert cuisine using Native and regional ingredients. Stylish setting with a strong focus on Tucson terroir.
Refined Southwestern dining at Hacienda Del Sol, known for regional ingredients, polished service, and a romantic desert setting.
Historic casual spot famous for Sonoran hot dogs and other Tucson staples. Lively, unfussy, and one of the city’s best-known local institutions.
Moderate for a US city. Hotels are often cheaper than major US hubs; dining is reasonable, but car use and limited transit can raise visitor costs.
Tip 18-20% in restaurants, more for great service. Taxis usually 10-15%. Round up or tip $1-2 at cafes.
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Tucson, AZ.
Find answers to the most common questions about traveling from Columbia, MO to Tucson, AZ by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Tucson, AZ, this guide helps you travel smarter and with confidence.

Most Columbia, MO to Tucson, AZ buses use the Columbia, Wabash Bus Station to Tucson, E 12th St (Bus Station) station pair, with some services arriving at Tuscon, University of Arizona Transportation Office. Use this guide to compare Columbia, MO and Tucson, AZ bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Columbia, Highway 40 W (Midway Truck Plaza) is 8 km from Columbia city centre. Public transport options include:
Columbia, Highway 40 W (Midway Truck Plaza) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Several fast food options available within the plaza.
Wi-Fi available inside the truck plaza building. ATMs are aTM machines are available inside the truck plaza.
Ticket office support is available at Columbia, Highway 40 W (Midway Truck Plaza).
Available at Columbia, Highway 40 W (Midway Truck Plaza): Parking, Taxis, WC.
Accessibility facilities are available at Columbia, Highway 40 W (Midway Truck Plaza): Wheelchair accessible facilities available.
Columbia, Wabash Bus Station has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Columbia, Wabash Bus Station. ATMs are available at Columbia, Wabash Bus Station.
Ticket office support is available at Columbia, Wabash Bus Station.
Available at Columbia, Wabash Bus Station: Parking, Taxis, WC.
Accessibility facilities are available at Columbia, Wabash Bus Station: Station is accessible for wheelchair users.
Tucson, E 12th St (Bus Station) is 3 km from Tucson city centre. Public transport options include:
Tucson, E 12th St (Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Tucson, E 12th St (Bus Station). ATMs are available at Tucson, E 12th St (Bus Station).
Ticket office support is available at Tucson, E 12th St (Bus Station).
Available at Tucson, E 12th St (Bus Station): Parking, Taxis, WC.
Accessibility facilities are available at Tucson, E 12th St (Bus Station): Basic accessibility features available.
Tuscon, University of Arizona Transportation Office is 2 km from Tucson city centre. Public transport options include:
Tuscon, University of Arizona Transportation Office has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Free Wi-Fi available for visitors. ATMs are available at Tuscon, University of Arizona Transportation Office.
Ticket office support is available at Tuscon, University of Arizona Transportation Office.
Available at Tuscon, University of Arizona Transportation Office: Parking, Taxis, WC.
Accessibility facilities are available at Tuscon, University of Arizona Transportation Office: Facility is wheelchair accessible.
Check bus stations information for Columbia, MO and Tucson, AZ, including where buses depart and arrive on this route.