Columbia, MO to Des Moines, IA bus with Greyhound

Mon, Sep 21
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2,000+ travel companies
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The cheapest and fastest buses from Columbia, MO to Des Moines, IA

Showing times, prices and bookable tickets for Sep 21

Cheapest price on Sep 21

CHF108

Average ticket price on Sep 21

CHF108

Fastest journey on Sep 21

8 h 5 m

Average journey duration on Sep 21

8 h 5 m

Buses on Sep 21

1

Distance

314 km

Cheap tickets

The best way to find a cheap bus ticket from Columbia, MO to Des Moines, IA is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Columbia, MO to Des Moines, IA will cost around CHF108 if you buy it on the day, but the cheapest tickets can be found for only CHF108.

Fast buses

It's difficult to get from Columbia, MO to Des Moines, IA without transferring at least once.

  • Greyhound USA
    2:40 PM8h05
    Columbia, MO
    10:45 PMDes Moines, IA
    CHF1081One-way
    1 transfer

Travel Information

Compare bus for Columbia, MO to Des Moines, IA

Omio recommends booking the bus as it is the most popular option from Columbia, MO to Des Moines, IA among Omio's users. If you are prioritising price, take the bus, with an average ticket price of CHF65 For those with little time, consider booking a bus, which has an average total journey time of 11h 50m. Average ticket prices depend on the travel mode: a bus costs an average of CHF65, while a bus costs an average of CHF65.

Distance: 195 miles (314 km)

Compare bus with

Most popular
Bus
Driving

CHF65

Average price

Cheapest

CHF39

Average price

(fuel + tolls)

11h 50m

Average total duration

Fastest

11h 20m

Onboard

+

30m

Additional time*

4h 6m

Average total duration

(door-to-door)

Greyhound

Most popular bus company

Your own car or car rental

Direct Options

Direct Options

The cheapest way to travel from Columbia, MO to Des Moines, IA is a bus with an average price of CHF65.
The fastest way to travel from Columbia, MO to Des Moines, IA is by bus with an average journey time of 11h 20m.
Yes, you can take a bus between Columbia, MO and Des Moines, IA.
We recommend using the bus as it is the most popular way to get from Columbia, MO to Des Moines, IA among Omio's users.
Take the bus. It's the cheapest way to make this trip, and the price gap is usually bigger than people expect.

Tickets start at around CHF65 compared to roughly CHF39 in fuel and tolls — a saving of about CHF-26.53. The journey takes 11h 20m versus 4h 6m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.

Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.

Columbia, MO to Des Moines, IA Bus Timetables

OperatorDeparture TimeArrival TimeDurationDeparture daysCheapest price
Operator
Greyhound
Departure Time
08:30AM
Arrival Time
11:05PM
Duration
14h35
Departure days
Fri
Cheapest price
CHF66
Operator
Greyhound
Departure Time
10:40AM
Arrival Time
11:05PM
Duration
12h25
Departure days
Fri
Cheapest price
CHF65
Operator
Greyhound
Departure Time
01:30PM
Arrival Time
04:45AM
Duration
15h15
Departure days
Tue
Cheapest price
CHF74
Operator
Greyhound USA
Departure Time
02:40PM
Arrival Time
10:45PM
Duration
8h05
Departure days
Mon, Wed, Thu, Fri, Sat, Sun
Cheapest price
CHF53
Operator
Greyhound
Departure Time
03:15PM
Arrival Time
11:45PM
Duration
8h30
Departure days
Fri
Cheapest price
CHF49

Live departures

Columbia, MO to Des Moines, IA bus times

The table below shows live departures for Columbia, MO to Des Moines, IA buses for tomorrow, Monday, September 21. You can also manually refresh the results below to see updated bus journeys.

Last updated at
ProviderDepartsDurationArrivesTransfers
Tickets
Greyhound USA2:40 PM Columbia, MO
8h05
10:45 PM Des Moines, IA1 transfer

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets Columbia, MO to Des Moines, IA by bus

Compare bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Mon
Sep 21
Tue
Sep 22
Wed
Sep 23
Thu
Sep 24
Fri
Sep 25
Sat
Sep 26
Sun
Sep 27

Why should you book Columbia, MO to Des Moines, IA buses with Omio?

Greyhound operates all buses services from Columbia, MO to Des Moines, IA.
Omio is an official ticket reseller for all your travel options from Columbia, MO to Des Moines, IA.

Why book with Omio vs Greyhound?

  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.

Journey information

Overview: Bus from Columbia, MO to Des Moines, IA

USAUSA
USAUSA
Icon of bus

Buses from Columbia, MO to Des Moines, IA run on average 2 times per day, taking around 11h 20m. Cheap bus tickets for this journey start at CHF64 if you book in advance.

The earliest bus runs at 13:30, the last at 20:15. The fastest bus covers the 195 miles (314 km) distance in 10h 40m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
195 miles (314 km)
Average bus duration
11h 20m
Cheapest ticket price
CHF64
Buses per day
2
Fastest bus
10h 40m
First bus
1:30 PM
Last bus
8:15 PM
Cheapest Month
Jul
Cheapest Day
Sat
High Season
Jul - Sep
Low Season
Apr - Jun
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Bus providers: Greyhound from Columbia, MO to Des Moines, IAYou can travel by bus between Columbia, MO to Des Moines, IA with Greyhound for as low as CHF64. When you search for schedules and tickets, Omio will show you the best journey

Greyhound

About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Greyhound Duration
10h 40m
Cheapest Greyhound Price
CHF64
Greyhound frequency
2 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.

Complete guide to Des Moines, IA

Things to do in Des Moines, IA

Discover the best of Des Moines, IA — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Des Moines, IA trip today.

  • Must visit

Des Moines Art Center

Leading art museum with strong American, contemporary, and decorative arts collections, plus a sculpture park just outside downtown.

  • Recommended

State Historical Museum of Iowa

Compact state museum covering Iowa history, culture, and artifacts. A practical stop for visitors wanting context before exploring the city.

  • Recommended

Science Center of Iowa

Science museum with interactive exhibits, a planetarium, and hands-on displays suited to families and curious adults alike.

FAQs: Bus from Columbia, MO to Des Moines, IA

Find answers to the most common questions about traveling from Columbia, MO to Des Moines, IA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Des Moines, IA, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Columbia, MO to Des Moines, IA can start from as little as CHF64 when you book in advance. The average bus ticket price for Columbia, MO to Des Moines, IA is CHF65 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Columbia, MO to Des Moines, IA is 10h 40m to travel the 195 miles (314 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Columbia, MO to Des Moines, IA leaves at 1:30 PM. Plan your trip with the Journey Planner from Omio.
The latest bus from Columbia, MO to Des Moines, IA leaves at 8:15 PM.
There are 2 buses a day from Columbia, MO to Des Moines, IA which require at least one change with Greyhound. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Columbia, MO to Des Moines, IA, you can count on Greyhound for the best way to get you to Des Moines, IA. You can also check all possible bus companies who offer a service between Columbia, MO and Des Moines, IA and compare the amenities they offer before buying a bus ticket.
When departing from Columbia, MO , you have various bus station options to start your journey from including Columbia, Highway 40 W (Midway Truck Plaza), MO, Columbia, Wabash Bus Station, MO . When arriving in Des Moines, IA , you can end your journey in bus stations like Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.), IA .Passengers board the bus most frequently from Columbia, Highway 40 W (Midway Truck Plaza), MO, which is located around 4 miles (8 km) away from the city centre, and they get off the bus at Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.), IA, located 3 away from the city centre.
A trip to Des Moines, IA from Columbia, MO is worth doing but not as a day trip with a journey time of 10h 40m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Columbia, MO to Des Moines, IA is July.
Yes, you can take a bus between Columbia, MO and Des Moines, IA.
Yes, the following accessibility options are available when taking the bus from Columbia, MO to Des Moines, IA:
  • Greyhound
    • Assistance
    • Priority seating
    • Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Columbia, MO to Des Moines, IA for bus company Greyhound.
Whether you can cancel your bus ticket from Columbia, MO to Des Moines, IA depends on the bus companies:
  • Greyhound
    • You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Columbia, MO to Des Moines, IA.
Yes, the following luggage options are included when booking a bus ticket from Columbia, MO to Des Moines, IA:
  • Greyhound
    • One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from Columbia, MO to Des Moines, IA:
  • Greyhound
    • $15 per additional bag.
Unfortunately, pets are not allowed on the bus from Columbia, MO to Des Moines, IA.
You can reserve your seat on the bus from Columbia, MO to Des Moines, IA with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from Columbia, MO to Des Moines, IA with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from Columbia, MO to Des Moines, IA with the following bus company: Greyhound.
Since neither Columbia, MO nor Des Moines, IA are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the bus as it is the most popular way to get from Columbia, MO to Des Moines, IA among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Des Moines, IA, travelers should be cautious of pickpocketing and occasional vehicle break-ins, especially in crowded areas and parking lots. Common scams include fake ticket sellers for local events and unofficial ride services. Staying alert in busy downtown spots and using authorized transportation options helps ensure safety.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

popular bus stations

Popular bus stations from Columbia, MO to Des Moines, IA

Most Columbia, MO to Des Moines, IA buses use the Columbia, Highway 40 W (Midway Truck Plaza) to Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.) station pair. Use this guide to compare Columbia, MO and Des Moines, IA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.

Departure bus stations in Columbia
Arrival bus stations in Des Moines

Which Columbia, MO station do buses to Des Moines, IA leave from?

Buses from Columbia, MO to Des Moines, IA leave from Columbia, Highway 40 W (Midway Truck Plaza). The station is 5 miles (9 km) from Columbia, MO city centre at US-40, United States.
Columbia, Highway 40 W (Midway Truck Plaza)US-40, United StatesWifiParkingDiningATMTaxisAccessibilityWCShowerTicket Office
City-centre transport

Getting to Columbia, Highway 40 W (Midway Truck Plaza) from Columbia city centre

Columbia, Highway 40 W (Midway Truck Plaza) is 8 km from Columbia city centre. Public transport options include:

TrainMissouri River Runner, Lincoln Service Missouri River Runner · 4h 1m · CHF185
BusGreyhound US0175s · 2h 45m · CHF20

Columbia, Highway 40 W (Midway Truck Plaza) bus station facilities and services

Columbia, Highway 40 W (Midway Truck Plaza) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.

Food and drink

Food options include: Several fast food options available within the plaza.

Wi-Fi and ATMs

Wi-Fi available inside the truck plaza building. ATMs are aTM machines are available inside the truck plaza.

Tickets and information

Ticket office support is available at Columbia, Highway 40 W (Midway Truck Plaza).

Parking, taxis and toilets

Available at Columbia, Highway 40 W (Midway Truck Plaza): Parking, Taxis, WC.

Accessibility

Accessibility facilities are available at Columbia, Highway 40 W (Midway Truck Plaza): Wheelchair accessible facilities available.

Columbia, Wabash Bus Station126 N 10th St, Columbia, MO 65201, USAWifiParkingATMTaxisAccessibilityWCShowerTicket Office
City-centre transport

Getting to Columbia, Wabash Bus Station from Columbia city centre

TRUE

Columbia, Wabash Bus Station bus station facilities and services

Columbia, Wabash Bus Station has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.

Wi-Fi and ATMs

Wi-Fi is available at Columbia, Wabash Bus Station. ATMs are available at Columbia, Wabash Bus Station.

Tickets and information

Ticket office support is available at Columbia, Wabash Bus Station.

Parking, taxis and toilets

Available at Columbia, Wabash Bus Station: Parking, Taxis, WC.

Accessibility

Accessibility facilities are available at Columbia, Wabash Bus Station: Station is accessible for wheelchair users.

More options for your journey from Columbia, MO to Des Moines, IA

Here are some other resources that might have the information you need

HomeBusesBuses in USABus tickets to Des Moines, IAColumbia, MO to Des Moines, IA bus

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