- Must visit
Des Moines Art Center
Major contemporary and modern art museum with a respected collection and notable architecture by Eliel Saarinen, I. M. Pei, and Richard Meier.
Cheapest price
$131
Average price
$131
Fastest journey
8 h 5 m
Average duration
8 h 5 m
Buses per day
1
Distance
314 km
The best way to find a cheap bus ticket from Columbia, MO to Des Moines, IA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Columbia, MO to Des Moines, IA will cost around $131 if you buy it on the day, but the cheapest tickets can be found for only $131.
It's difficult to get from Columbia, MO to Des Moines, IA without transferring at least once.


Omio recommends booking the bus as it is the most popular option from Columbia, MO to Des Moines, IA among Omio's users. If you are prioritising price take the bus with prices starting from $90. For those with little time consider booking a bus which can get you there in 15h 15m. The ticket price range depends on the travel mode: a bus costs an average of $90, and a bus costs an average of $90.
Distance: 195 miles (314 km)
Most popular Bus | Driving |
|---|---|
$90 Average price Cheapest | $46 Average price (fuel + tolls) |
15h 45m Average total duration Fastest 15h 15m Onboard + 30m Additional time* | 4h 6m Average total duration (door-to-door) |
Direct Options | Direct Options |
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 01:30PM | Arrival Time 04:45AM | Duration 15h15 | Departure days Tue | Cheapest price $90 |
Operator Greyhound USA | Departure Time 02:40PM | Arrival Time 10:45PM | Duration 8h05 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price $131 |
The table below shows live departures for Columbia, MO to Des Moines, IA buses for tomorrow, Monday, June 22. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 2:40 PM Columbia, MO | 8h05 | 10:45 PM Des Moines, IA | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Columbia, MO to Des Moines, IA run on average 2 times per day, taking around 15h 15m. Cheap bus tickets for this journey start at $90 (€74) if you book in advance.
The earliest bus runs at 13:30, the last at 13:30. The fastest bus covers the 195 miles (314 km) distance in 15h 15m.
Distance 195 miles (314 km) |
Average bus duration 15h 15m |
Cheapest ticket price $90 (€74) |
Buses per day 2 |
Fastest bus 15h 15m |
First bus 1:30 PM |
Last bus 1:30 PM |
Cheapest Month Apr |
Cheapest Day Tue |
High Season Apr - Jun |
Low Season Jul - Sep |
Discover the best of Des Moines — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Des Moines trip today.
Major contemporary and modern art museum with a respected collection and notable architecture by Eliel Saarinen, I. M. Pei, and Richard Meier.
Museum covering Iowa history through permanent and rotating exhibits, located in the State Historical Building near the Capitol complex.
Historic house museum inspired by English manor architecture, featuring art, books, antiques, and landscaped grounds.
Downtown sculpture park featuring major contemporary works in an open urban green space, highly popular for walks and photos.
Trendy neighborhood east of the river known for independent shops, murals, historic streetscapes, and a lively local atmosphere.
Signature downtown walking area along the Des Moines River with bridges, lighting, event spaces, and skyline views.
An Iowa classic: a pork cutlet pounded thin, breaded, fried, and served on a bun, often comically larger than the bread. It is one of the state's most iconic comfort foods.
Iowa sweet corn is a summer staple, prized for its tenderness and natural sweetness. It is commonly eaten grilled, boiled, or buttered at fairs, cookouts, and seasonal meals.
A seasoned ground beef sandwich served loose on a bun rather than formed into a patty. It is a longtime Midwestern lunch-counter favorite strongly associated with Iowa.
A respected fine-dining venue in a historic house, serving refined American and Italian-influenced dishes in an intimate setting. A strong choice for a special night out.
An upscale steakhouse known for classic service, prime steaks, and an elegant atmosphere. It is one of Des Moines' best-known options for a high-end dinner.
A popular Des Moines burger spot known for creative burgers, boozy shakes, and a lively horror-themed atmosphere. A dependable place to try a strong local casual dining favorite.
Moderate by U.S. standards. Hotels and dining are usually cheaper than in major coastal cities, though downtown and event periods cost more.
Tip 18-20% at restaurants; 20%+ for great service. Tip bartenders USD 1-2 per drink, taxis 10-15%, hotel staff USD 2-5, and round up for casual services.
Find answers to the most common questions about traveling from Columbia, MO to Des Moines, IA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Des Moines, IA, this guide helps you travel smarter and with confidence.

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