- Must visit
Columbia Museum of Art
State art museum with American, European, and contemporary works plus rotating exhibitions in a spacious downtown building.
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Journey information
Overview: Bus from San Diego, CA to Columbia, MO
USAUSA
Buses from San Diego, CA to Columbia, MO run on average 7 times per day, taking around 40h 44m. Cheap bus tickets for this journey start at lei1302 if you book in advance.
The earliest bus runs at 14:40, the last at 20:35. The fastest bus covers the 1450 miles (2334 km) distance in 39h 5m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 1450 miles (2334 km) |
Average bus duration 40h 44m |
Cheapest ticket price lei1302 |
Buses per day 7 |
Fastest bus 39h 5m |
First bus 2:40 PM |
Last bus 8:35 PM |
Cheapest Month Nov |
Cheapest Day Thu |
High Season Jan - Mar |
Low Season Jul - Sep |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
San Diego, CA to Columbia, MO Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound Mexico | Departure Time 07:00AM | Arrival Time 10:40AM | Duration 51h40 | Departure days Tue, Wed, Fri, Sat | Cheapest price lei2638 |
Operator Greyhound | Departure Time 04:50PM | Arrival Time 03:40PM | Duration 46h50 | Departure days Thu | Cheapest price lei1131 |
Operator Greyhound | Departure Time 08:10PM | Arrival Time 03:30PM | Duration 43h20 | Departure days Thu | Cheapest price lei1524 |
Live departures
San Diego, CA to Columbia, MO bus times
The table below shows live departures for San Diego, CA to Columbia, MO buses for today, Saturday, October 10. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
 | 7:00 AM San Diego, CA | 51h40 | 10:40 AM Columbia, MO | 3 transfers | |
| 7:00 AM San Diego, CA | 51h40 | 10:40 AM Columbia, MO | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Why should you book San Diego, CA to Columbia, MO buses with Omio?
Greyhound operates all buses services from San Diego, CA to Columbia, MO.
Omio is an official ticket reseller for all your travel options from San Diego, CA to Columbia, MO.
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
Bus providers: Greyhound from San Diego, CA to Columbia, MOYou can travel by bus between San Diego, CA to Columbia, MO with Greyhound for as low as lei1302. When you search for schedules and tickets, Omio will show you the best journey
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Greyhound Duration
39h 5m
Cheapest Greyhound Price
lei1302
Greyhound frequency
7 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Complete guide to Columbia, MO
Things to do in Columbia, MO
Discover the best of Columbia, MO — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Columbia, MO trip today.
- Must visit
South Carolina State Museum
Interactive state museum covering art, history, science, and technology, with broad exhibits suitable for families and curious adults.
- Recommended
Woodrow Wilson Family Home
Historic house museum presenting 19th-century urban life, decorative arts, and preservation work in downtown Columbia.
- Must visit
The Vista
Lively downtown entertainment district with restored warehouses, public art, shops, and an easy walkable atmosphere near major attractions.
- Must visit
Riverfront Park
Riverfront greenway with boardwalks, bridges, canal views, and shaded trails. Popular for walking, biking, and scenic city escapes.
- Recommended
Congaree Vista Historic District
Compact downtown district with galleries, restored homes, and tree-lined streets. Good for strolling and seeing Columbia’s historic character.
- Gluten-free
South Carolina Mustard-Based Barbecue
A Midlands staple of slow-smoked pork, usually chopped or pulled and dressed with a mustard-based sauce rooted in South Carolina German heritage.
- Gluten-free
Barbecue Hash And Rice
Hash made from finely chopped pork and offal simmered with spices, traditionally served over rice at barbecue joints and family gatherings.
- Vegetarian
- Gluten-free
Cheese Grits
Stone-ground corn grits cooked creamy, often with butter or cheese. They are a long-standing Southern breakfast and supper staple across Columbia.
Motor Supply Co. Bistro
Stylish Southern restaurant serving shrimp and grits, fried green tomatoes, and modern regional plates in a lively downtown setting.
Home Team BBQ
Beloved local barbecue spot known for South Carolina pulled pork, ribs, brisket, hash and rice, with a casual counter-service atmosphere.
DiPrato's
Casual local favorite for pimento cheese, biscuits, grits, sandwiches, and Southern breakfast plates in a relaxed neighborhood setting.
$ US dollar
Moderate for a US city. Hotels and dining are mid-priced, transit costs are low, and budget food is easy to find compared with larger East Coast destinations.
Average meal costs
- Budget
- $10-15 for fast food or casual lunch.
- Mid-range
- $18-35 per person for a restaurant meal.
- Fine dining
- $50+ per person for upscale dining.
- Coffee
- $3-5 for coffee or cappuccino.
Tipping culture
Tip 15-20% at restaurants, 10-15% for taxis, and $1-2 for café drinks if there is table service.
FAQs: Bus from San Diego, CA to Columbia, MO
Find answers to the most common questions about traveling from San Diego, CA to Columbia, MO by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Columbia, MO, this guide helps you travel smarter and with confidence.
Cheap bus tickets from San Diego, CA to Columbia, MO can start from as little as lei1302 when you book in advance. The average bus ticket price for San Diego, CA to Columbia, MO is lei1375 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from San Diego, CA to Columbia, MO is 39h 5m to travel the 1450 miles (2334 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from San Diego, CA to Columbia, MO leaves at 2:40 PM. Plan your trip with the Journey Planner from Omio.
The latest bus from San Diego, CA to Columbia, MO leaves at 8:35 PM.
There are 7 buses a day from San Diego, CA to Columbia, MO which require at least one change with Greyhound. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from San Diego, CA to Columbia, MO, you can count on Greyhound for the best way to get you to Columbia, MO. You can also check all possible bus companies who offer a service between San Diego, CA and Columbia, MO and compare the amenities they offer before buying a bus ticket.
When departing from San Diego, CA , you have various bus station options to start your journey from including San Diego, Congress Street (Old Town Park), CA, San Diego, San Ysidro Transit Center, San Diego, West Harbor Drive (The Headquarters at Seaport District), CA . When arriving in Columbia, MO , you can end your journey in bus stations like Columbia, Highway 40 W (Midway Truck Plaza), MO, Columbia, Wabash Bus Station, MO .Passengers board the bus most frequently from San Diego, Congress Street (Old Town Park), CA, which is located around 3 miles (5 km) away from the city centre, and they get off the bus at Columbia, Highway 40 W (Midway Truck Plaza), MO, located 8 away from the city centre.
Yes, you can take a bus between San Diego, CA and Columbia, MO.
Yes, the following accessibility options are available when taking the bus from San Diego, CA to Columbia, MO:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from San Diego, CA to Columbia, MO for bus company Greyhound.
Whether you can cancel your bus ticket from San Diego, CA to Columbia, MO depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from San Diego, CA to Columbia, MO.
Yes, the following luggage options are included when booking a bus ticket from San Diego, CA to Columbia, MO:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from San Diego, CA to Columbia, MO:
- Greyhound
- $15 per additional bag.
Unfortunately, pets are not allowed on the bus from San Diego, CA to Columbia, MO.
You can reserve your seat on the bus from San Diego, CA to Columbia, MO with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from San Diego, CA to Columbia, MO with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from San Diego, CA to Columbia, MO with the following bus company: Greyhound.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Columbia, MO, travelers should be cautious of petty theft and vehicle break-ins, especially in busy areas and parking lots. Common scams include overcharging by unofficial taxi or ride-share services and fake ticket sellers near popular events. Staying aware of surroundings and using authorized transportation options helps ensure safety.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from San Diego, CA to Columbia, MO
Most San Diego, CA to Columbia, MO buses use the San Diego, Congress Street (Old Town Park) to Columbia, Highway 40 W (Midway Truck Plaza) station pair, with some services arriving at Columbia, Wabash Bus Station. Use this guide to compare San Diego, CA and Columbia, MO bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in San Diego
Arrival bus stations in Columbia
Which San Diego, CA station do buses to Columbia, MO leave from?
Buses from San Diego, CA to Columbia, MO leave from San Diego, Congress Street (Old Town Park). The station is 3 miles (6 km) from San Diego, CA city centre at Congress St, San Diego, CA 92110, USA.
San Diego, Congress Street (Old Town Park)Congress St, San Diego, CA 92110, USA
City-centre transport
Getting to San Diego, Congress Street (Old Town Park) from San Diego city centre
San Diego, Congress Street (Old Town Park) is 5 km from San Diego city centre. Public transport options include:
BusFlixBus 2017 · 20m · lei6
83 · 26m · lei28
TramGreen, Blue, Event · 16m · every ~18 min
Blue · 21m · every ~9 min
San Diego, Congress Street (Old Town Park) bus station facilities and services
San Diego, Congress Street (Old Town Park) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Several dining options nearby.
Wi-Fi and ATMs
Wi-Fi is available at San Diego, Congress Street (Old Town Park). ATMs are available at San Diego, Congress Street (Old Town Park).
Tickets and information
Ticket office support is available at San Diego, Congress Street (Old Town Park).
Parking, taxis and toilets
Available at San Diego, Congress Street (Old Town Park): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at San Diego, Congress Street (Old Town Park): Wheelchair accessible routes available.
San Diego, San Ysidro Transit CenterSan Ysidro Station, San Diego, CA 92173, USA
City-centre transport
Getting to San Diego, San Ysidro Transit Center from San Diego city centre
San Diego, San Ysidro Transit Center is 22 km from San Diego city centre. Public transport options include:
BusFlixBus 2017 · 25m · lei11
910 · 41m · lei28
TramBlue · 41m · lei80 · every ~14 min
Blue · 43m · lei80 · every ~14 min
San Diego, San Ysidro Transit Center bus station facilities and services
San Diego, San Ysidro Transit Center has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Several fast food eateries located nearby.
Wi-Fi and ATMs
Wi-Fi is available at San Diego, San Ysidro Transit Center. ATMs are available near the entrance.
Tickets and information
Ticket office support is available at San Diego, San Ysidro Transit Center.
Parking, taxis and toilets
Available at San Diego, San Ysidro Transit Center: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at San Diego, San Ysidro Transit Center: Wheelchair accessible with ramps.
San Diego, West Harbor Drive (The Headquarters at Seaport District)W Harbor Dr, San Diego, CA, USA
City-centre transport
Getting to San Diego, West Harbor Drive (The Headquarters at Seaport District) from San Diego city centre
San Diego, West Harbor Drive (The Headquarters at Seaport District) is 1 km from San Diego city centre. Public transport options include:
TRUE
San Diego, West Harbor Drive (The Headquarters at Seaport District) bus station facilities and services
San Diego, West Harbor Drive (The Headquarters at Seaport District) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Several dining options are in the area.
Wi-Fi and ATMs
Wi-Fi is available at San Diego, West Harbor Drive (The Headquarters at Seaport District). ATMs are available at San Diego, West Harbor Drive (The Headquarters at Seaport District).
Tickets and information
Ticket office support is available at San Diego, West Harbor Drive (The Headquarters at Seaport District).
Parking, taxis and toilets
Available at San Diego, West Harbor Drive (The Headquarters at Seaport District): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at San Diego, West Harbor Drive (The Headquarters at Seaport District): Accessible for persons with disabilities.
Which Columbia, MO station do buses from San Diego, CA arrive at?
Buses from San Diego, CA to Columbia, MO most often arrive at Columbia, Highway 40 W (Midway Truck Plaza). Some services arrive at Columbia, Wabash Bus Station, so check your ticket before travel to confirm your Columbia, MO arrival station.
Columbia, Highway 40 W (Midway Truck Plaza)US-40, United States
City-centre transport
Getting to Columbia, Highway 40 W (Midway Truck Plaza) from Columbia city centre
Columbia, Highway 40 W (Midway Truck Plaza) is 8 km from Columbia city centre. Public transport options include:
TrainMissouri River Runner, Lincoln Service Missouri River Runner · 4h 1m · lei1046
BusGreyhound US0175s · 2h 45m · lei114
Columbia, Highway 40 W (Midway Truck Plaza) bus station facilities and services
Columbia, Highway 40 W (Midway Truck Plaza) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Several fast food options available within the plaza.
Wi-Fi and ATMs
Wi-Fi available inside the truck plaza building. ATMs are aTM machines are available inside the truck plaza.
Tickets and information
Ticket office support is available at Columbia, Highway 40 W (Midway Truck Plaza).
Parking, taxis and toilets
Available at Columbia, Highway 40 W (Midway Truck Plaza): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Columbia, Highway 40 W (Midway Truck Plaza): Wheelchair accessible facilities available.
Columbia, Wabash Bus Station126 N 10th St, Columbia, MO 65201, USA
City-centre transport
Getting to Columbia, Wabash Bus Station from Columbia city centre
TRUE
Columbia, Wabash Bus Station bus station facilities and services
Columbia, Wabash Bus Station has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Columbia, Wabash Bus Station. ATMs are available at Columbia, Wabash Bus Station.
Tickets and information
Ticket office support is available at Columbia, Wabash Bus Station.
Parking, taxis and toilets
Available at Columbia, Wabash Bus Station: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Columbia, Wabash Bus Station: Station is accessible for wheelchair users.
Most popular bus connections from San Diego, CA
More options for your journey from San Diego, CA to Columbia, MO
Here are some other resources that might have the information you need
Most popular buses to and from Columbia, MO and San Diego, CA
Most popular bus connections to Columbia, MO
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