- Must visit
Columbia Museum of Art
The city’s leading art museum, known for its European, American, and Asian collections plus rotating exhibitions and events downtown.
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The cheapest and fastest buses from San Diego, CA to Columbia, MO
Showing times and prices for May 28
Cheapest price
$247
Average price
$290
Fastest journey
1 d 19 h 20 m
Average duration
1 d 21 h 5 m
Buses per day
2
Distance
2334 km
Cheap tickets
The best way to find a cheap bus ticket from San Diego, CA to Columbia, MO is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from San Diego, CA to Columbia, MO will cost around $290 if you buy it on the day, but the cheapest tickets can be found for only $247.
Fast buses
Of the 2 buses that leave San Diego, CA for Columbia, MO on Thu, May 28, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Thu, May 28 the direct buses cover the 2334 km distance in an average of 1 d 21 h 5 m but if you time it right, some buses will get you there in just 1 d 19 h 20 m .
On Thu, May 28 the slowest buses will take 1 d 22 h 50 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
4:50 PM46h50San Diego, CA3:40 PMColumbia, MO$2471One-way0 transfers- 8:10 PM43h20San Diego, CA3:30 PMColumbia, MO$3321One-way0 transfers
- 8:10 PM43h20San Diego, CA3:30 PMColumbia, MO$3321One-way0 transfers
- 4:50 PM46h50San Diego, CA3:40 PMColumbia, MO$2471One-way0 transfers
Travel Information
Compare bus and flight for San Diego, CA to Columbia, MO
Omio recommends booking the bus as it is the most popular option from San Diego, CA to Columbia, MO among Omio's users. If you are prioritising price take the bus with prices starting from $247. For those with little time consider booking a flight which can get you there in 7h 17m. The ticket price range depends on the travel mode: a bus costs an average of $247, and a flight costs an average of $520.
Distance: 1450 miles (2334 km)
Compare bus with
Most popular Bus | Flight | Driving |
|---|---|---|
$290 Average price Cheapest | $551 Average price | $342 Average price (fuel + tolls) |
45h 35m Average total duration 45h 5m Onboard + 30m Additional time* | 10h 17m Average total duration Fastest 7h 17m Onboard + 3h 0m Additional time* | 25h 24m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options |
The cheapest way to travel from San Diego, CA to Columbia, MO is a bus with an average price of $290 (€233).
This is compared to other travel options from San Diego, CA to Columbia, MO:
A bus is $261 (€211) less than a flight for this route with tickets for a flight from San Diego, CA to Columbia, MO costing on average $551 (€444).
The fastest way to travel from San Diego, CA to Columbia, MO is by flight with an average journey time of 7h 17m.
Other travel options to Columbia, MO take longer:
Bus takes on average 45h 5m.
It's helpful to compare your options as there are 2 ways to travel between San Diego, CA and Columbia, MO including taking a bus and flight.
We recommend using the bus as it is the most popular way to get from San Diego, CA to Columbia, MO among Omio's users.
Take the bus. On this route, it's both cheaper and quicker than driving.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
San Diego, CA to Columbia, MO Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound Mexico | Departure Time 07:00AM | Arrival Time 10:40AM | Duration 51h40 | Departure days Tue, Wed, Fri, Sat | Cheapest price $575 |
Operator Greyhound | Departure Time 04:50PM | Arrival Time 03:40PM | Duration 46h50 | Departure days Thu | Cheapest price $247 |
Operator Greyhound | Departure Time 08:10PM | Arrival Time 03:30PM | Duration 43h20 | Departure days Thu | Cheapest price $332 |
Compare prices and tickets San Diego, CA to Columbia, MO by bus or flight
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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May 28
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Why should you book San Diego, CA to Columbia, MO buses with Omio?
Greyhound operates all buses services from San Diego, CA to Columbia, MO.
Omio is an official ticket reseller for all your travel options from San Diego, CA to Columbia, MO.
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus and flight to ensure you get the best deal for traveling from San Diego, CA to Columbia, MO.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including bus and flight to find the ideal travel option from San Diego, CA to Columbia, MO.
Journey information
Overview: Bus from San Diego, CA to Columbia, MO
USAUSA
Buses from San Diego, CA to Columbia, MO run on average 9 times per day, taking around 45h 5m. Cheap bus tickets for this journey start at $247 (€199) if you book in advance.
The earliest bus runs at 14:40, the last at 20:35. The fastest bus covers the 1450 miles (2334 km) distance in 43h 20m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 1450 miles (2334 km) |
Average bus duration 45h 5m |
Cheapest ticket price $247 (€199) |
Buses per day 9 |
Fastest bus 43h 20m |
First bus 2:40 PM |
Last bus 8:35 PM |
Cheapest Month Nov |
Cheapest Day Thu |
High Season Jan - Mar |
Low Season Oct - Dec |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Bus providers: Greyhound from San Diego, CA to Columbia, MOYou can travel by bus between San Diego, CA to Columbia, MO with Greyhound for as low as $247 (€199). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
43h 20m
Cheapest Price
$247 (€199)
Greyhound frequency
2 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Complete guide to Columbia
Things to do in Columbia
Discover the best of Columbia — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Columbia trip today.
- Must visit
South Carolina State Museum
South Carolina’s largest museum, covering art, history, science, and technology in a large former mill on the riverfront.
- Recommended
McKissick Museum
A University of South Carolina museum focused on Southern history, culture, and changing exhibitions in a historic campus building.
- Must visit
Congaree National Park
A famous natural area near Columbia known for old-growth floodplain forest, boardwalks, kayaking, and striking photo opportunities.
- Must visit
Riverfront Park
A scenic urban park with riverside trails, canal history, industrial ruins, and some of the city’s most popular walking views.
- Must visit
Main Street District
The heart of downtown Columbia, lined with shops, public art, event spaces, and many of the city’s most photographed blocks.
- Gluten-free
South Carolina Barbecue
Slow-smoked pork, often chopped or pulled, traditionally served with the state’s distinctive mustard-based sauce. It is one of the signature foods of Columbia and the Midlands.
- Gluten-free
Hash And Rice
A classic Midlands dish made from finely chopped slow-cooked pork and gravy served over rice. It is deeply tied to old-school South Carolina barbecue culture.
- Gluten-free
Shrimp And Grits
Creamy grits topped with shrimp, usually with bacon, gravy, or a savory sauce. This Lowcountry favorite is widely loved in Columbia restaurants.
Halls Chophouse Columbia
Popular upscale steakhouse known for polished service, steaks, seafood, and a lively downtown dining scene.
Mr. Friendly's New Southern Cafe
Well-known neighborhood restaurant serving refined Southern dishes in a cozy setting in the Five Points area.
Motor Supply Co. Bistro
Established New American restaurant in the Vista known for creative seasonal menus, strong cocktails, and an upscale but relaxed atmosphere.
United States Dollar
Daily costs are moderate by U.S. standards. Casual dining is affordable, while hotels and upscale dining cost more.
Average meal costs
- Budget
- USD 10-15 for fast food or a simple lunch.
- Mid-range
- USD 18-35 per person at a casual sit-down restaurant.
- Fine dining
- USD 50+ per person before drinks and tax.
- Coffee
- USD 3-6 for drip coffee or a latte.
Tipping culture
Tip 18-20% at full-service restaurants; 20%+ for excellent service. Tip USD 1-2 per drink at bars, round up or tip 10-15% for taxis, and USD 2-5 for hotel staff as appropriate.
FAQs: Bus from San Diego, CA to Columbia, MO
Find answers to the most common questions about traveling from San Diego, CA to Columbia, MO by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Columbia, MO, this guide helps you travel smarter and with confidence.
Cheap bus tickets from San Diego, CA to Columbia, MO can start from as little as $247 (€199) when you book in advance. The average bus ticket price for San Diego, CA to Columbia, MO is $290 (€233) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from San Diego, CA to Columbia, MO is 43h 20m to travel the 1450 miles (2334 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from San Diego, CA to Columbia, MO leaves at 2:40 PM. Plan your trip with the Journey Planner from Omio.
The latest bus from San Diego, CA to Columbia, MO leaves at 8:35 PM.
There are 9 buses a day from San Diego, CA to Columbia, MO which require at least one change with Greyhound. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from San Diego, CA to Columbia, MO, you can count on Greyhound for the best way to get you to Columbia, MO. You can also check all possible bus companies who offer a service between San Diego, CA and Columbia, MO and compare the amenities they offer before buying a bus ticket.
A trip to Columbia, MO from San Diego, CA is worth doing but not as a day trip with a journey time of 43h 20m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from San Diego, CA to Columbia, MO is November.
It's helpful to compare your options as there are 2 ways to travel between San Diego, CA and Columbia, MO including taking a bus and flight.
Yes, the following accessibility options are available when taking the bus from San Diego, CA to Columbia, MO:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from San Diego, CA to Columbia, MO for bus company Greyhound.
Whether you can cancel your bus ticket from San Diego, CA to Columbia, MO depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from San Diego, CA to Columbia, MO.
Yes, the following luggage options are included when booking a bus ticket from San Diego, CA to Columbia, MO:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from San Diego, CA to Columbia, MO:
- Greyhound
- $15 per additional bag.
Unfortunately, pets are not allowed on the bus from San Diego, CA to Columbia, MO.
You can reserve your seat on the bus from San Diego, CA to Columbia, MO with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from San Diego, CA to Columbia, MO with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from San Diego, CA to Columbia, MO with the following bus company: Greyhound.
Since neither San Diego, CA nor Columbia, MO are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the bus as it is the most popular way to get from San Diego, CA to Columbia, MO among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Columbia, MO, travelers should be cautious of petty theft and vehicle break-ins, especially in busy areas and parking lots. Common scams include overcharging by unofficial taxi or ride-share services and fake ticket sellers near popular events. Staying aware of surroundings and using authorized transportation options helps ensure safety.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from San Diego, CA to Columbia, MO
San Diego
Columbia
The major bus station for departures in San Diego is San Diego, Congress Street (Old Town Park). Find all the information you need to know about services, amenities and connections at San Diego, Congress Street (Old Town Park) for your trip from San Diego to Columbia.
San Diego, Congress Street (Old Town Park)
information
San Diego, San Ysidro Transit Center
information
San Diego, West Harbor Drive (The Headquarters at Seaport District)
information
The major bus station for arrivals in Columbia is Columbia, Highway 40 W (Midway Truck Plaza). Find all the information you need to know about services, amenities and connections at Columbia, Highway 40 W (Midway Truck Plaza) for your trip to Columbia from San Diego.
Columbia, Highway 40 W (Midway Truck Plaza)
information
Columbia, Wabash Bus Station
information
More options for your journey from San Diego, CA to Columbia, MO
Here are some other resources that might have the information you need
Most popular buses to and from Columbia, MO and San Diego, CA
Most popular bus connections to Columbia, MO
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