Journey information
Overview: Charleston, SC to Chicago, IL flight
Flights from Charleston, SC to Chicago, IL depart on average 38 times per day, taking around 3h 39m. Cheap flight tickets for this journey start at $451 (€358) but you can travel from only $210 (€167) by bus.
There are 3 flights per day. The earliest flight runs at 05:00, the last at 22:12. The fastest flight covers the 756 miles (1217 km) distance in 2h 29m. October is the cheapest month to fly.
Distance 756 miles (1217 km) |
Average flight duration 3h 39m |
Cheapest ticket price $451 (€358) |
Flights per day 38 |
Direct flights 3 |
Fastest flight 2h 29m |
Cheapest month to travel October |
First flight 05:00 |
Last flight 22:12 |
Travel Information
Compare bus for Charleston, SC to Chicago, IL
Omio recommends booking the flight as it is the most popular option from Charleston, SC to Chicago, IL among Omio's users. If you are prioritising price take the bus with prices starting from €167. For those with little time consider booking a flight which can get you there in 3h 39m. The ticket price range depends on the travel mode: a bus costs an average of €167, and a flight costs an average of €358.
Distance: 756 miles (1217 km)
Compare flight with
Most popular Flight | Bus |
|---|---|
€358 Average price | €167 Average price Cheapest |
6h 39m Average total duration Fastest 3h 39m Onboard + 3h 0m Additional time* | 24h 43m Average total duration 24h 13m Onboard + 30m Additional time* |
![]() Most popular airline | ![]() Most popular bus company |
Direct Options | Direct Options |
Compare prices and tickets Charleston, SC to Chicago, IL by bus
Compare bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Charleston, SC to Chicago, IL flights with Omio?
Why book with Omio vs American Airlines?
- Compare with other providers: On Omio, you can not only buy tickets for American Airlines, but also compare tickets for the likes of to find the best option for your trip from Charleston, SC to Chicago, IL.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
Why book with Omio over Trip, Edreams or Skyscanner?
Airlines: American Airlines from Charleston, SC to Chicago, ILFind the best flights between Charleston, SC to Chicago, IL with Omio's travel partners American Airlines from $210 (€167). We can find you the best deals, schedules and tickets when comparing and booking the best trip.
American Airlines
FAQs: Charleston, SC to Chicago, IL Flight
Find answers to the most common questions about traveling from Charleston, SC to Chicago, IL by flight. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest flight, the cheapest option, or tips for making the most of your visit at Chicago, IL, this guide helps you travel smarter and with confidence.

- Chicago Air and Water Show, an exhilarating display of military and civilian aircraft performing daring maneuvers over Lake Michigan
- Lollapalooza, a massive music festival featuring top artists across multiple genres in Grant Park
- Chicago Gourmet, a premier culinary event celebrating the city's vibrant food scene with tastings, cooking demonstrations, and wine pairings.
- Memorial Day, the unofficial start of summer with vibrant outdoor activities and events
- Independence Day, spectacular fireworks and festive celebrations throughout the city
- Labor Day, a lively atmosphere with various festivals and pleasant weather.
popular airports
Popular airports from Charleston, SC to Chicago, IL
- Free Wi-Fi available throughout the airport.
- Shops include Hudson News and Tech on the Go, located in the main terminal.
- Parking available; short-term parking located near the terminal, approximately 0.47€ ($0.50) per hour.
- Restaurants are available, including Charleston Beer Works (casual dining) and Caviar & Bas (café), located in the main terminal.
- Available outside the terminal.
- Ramps, assistance
- Available throughout the airport.
- Hotels like the DoubleTree by Hilton within walking distance.
- The Club CHS lounge available for travelers.
- Lost and Found located in the main terminal near baggage claim.
- Car rental services are available in the rental car pavilion near baggage claim.
- Bus Route 11, North Charleston Transit Center, 12 miles
- Free Wi-Fi available throughout the airport.
- Shops are located in all terminals, including duty-free and brands like Hudson and MAC Cosmetics.
- Parking available with options including hourly, daily, and economy lots, approximately 2.85€ ($3) per hour.
- Restaurants are located in all terminals, offering a variety of cuisines including American and intertiol. Top options include Tortas Frontera and Publican Tavern.
- Available outside the terminal.
- Elevators, ramps, toilets
- Available throughout the airport.
- Hotels such as Hilton Chicago O'Hare are located on airport grounds, with others like the Hyatt Regency nearby.
- Showers are available in some lounges, such as the United Club, but access may require a fee or membership.
- Lounges available, including United Club and American Airlines Admirals Club.
- Lost and Found located in terminal 1, near the baggage claim area.
- Car rental services are available at the Multi-Modal Facility, with companies like Hertz and Avis.
- CTA Blue Line, O'Hare Station, 45 minutes to city center
Most popular flights from Charleston, SC
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