- Must visit
Vatican Museums
World-famous papal museums with the Sistine Chapel, Raphael Rooms, and major classical collections.
The best way to find a cheap bus ticket from Brno to Rome is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Brno to Rome will cost around $91 if you buy it on the day, but the cheapest tickets can be found for only $90.
It's difficult to get from Brno to Rome without transferring at least once.
FlixBus · FlixBus
|
| ||||||||||||
FlixBus · FlixBus
|
| ||||||||||||
FlixBus · FlixBus · FlixBus
|
| ||||||||||||
FlixBus · FlixBus
|
| ||||||||||||
FlixBus · FlixBus
|
| ||||||||||||
FlixBus · FlixBus
|
| ||||||||||||
FlixBus · FlixBus · FlixBus
|
| ||||||||||||
FlixBus · FlixBus
|
| ||||||||||||
Buses from Brno to Rome run on average 7 times per day, taking around 19h 15m. Cheap bus tickets for this journey start at $72 but you can travel from only $12 by train.
The earliest bus runs at 01:35, the last at 23:50. The fastest bus covers the 542 miles (873 km) distance in 16h 20m.
Plan this route
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Brno to Rome.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 07:15AM | Arrival Time 10:15AM | Duration 27h00 | Departure days Sun | Cheapest price $132 |
Operator FlixBus | Departure Time 08:15AM | Arrival Time 11:15AM | Duration 27h00 | Departure days Mon, Thu, Sun | Cheapest price $85 |
Operator FlixBus | Departure Time 08:55AM | Arrival Time 07:20AM | Duration 22h25 | Departure days Sun | Cheapest price $92 |
Operator FlixBus | Departure Time 09:15AM | Arrival Time 09:30AM | Duration 24h15 | Departure days Tue, Fri, Sat | Cheapest price $90 |
Operator FlixBus | Departure Time 12:10PM | Arrival Time 12:20PM | Duration 24h10 | Departure days Thu, Sat | Cheapest price $94 |
Operator FlixBus | Departure Time 12:25PM | Arrival Time 03:05PM | Duration 26h40 | Departure days Fri, Sat | Cheapest price $114 |
Operator FlixBus | Departure Time 01:10PM | Arrival Time 01:20PM | Duration 24h10 | Departure days Wed, Fri | Cheapest price $109 |
Operator FlixBus | Departure Time 01:30PM | Arrival Time 01:20PM | Duration 23h50 | Departure days Sat | Cheapest price $119 |
Operator FlixBus | Departure Time 03:10PM | Arrival Time 04:00PM | Duration 24h50 | Departure days Thu | Cheapest price $88 |
Operator FlixBus | Departure Time 06:00PM | Arrival Time 02:45PM | Duration 20h45 | Departure days Tue | Cheapest price $91 |
Operator FlixBus | Departure Time 06:10PM | Arrival Time 06:05PM | Duration 23h55 | Departure days Tue | Cheapest price $91 |
Operator FlixBus | Departure Time 06:45PM | Arrival Time 02:45PM | Duration 20h00 | Departure days Wed | Cheapest price $99 |
Operator FlixBus | Departure Time 07:20PM | Arrival Time 02:45PM | Duration 19h25 | Departure days Fri, Sat | Cheapest price $106 |
Operator FlixBus | Departure Time 07:50PM | Arrival Time 03:25PM | Duration 19h35 | Departure days Thu | Cheapest price $169 |
Operator FlixBus | Departure Time 08:50PM | Arrival Time 07:25PM | Duration 22h35 | Departure days Sun | Cheapest price $105 |
Operator FlixBus | Departure Time 09:50PM | Arrival Time 05:25PM | Duration 19h35 | Departure days Tue, Wed, Fri, Sat | Cheapest price $91 |
Operator FlixBus | Departure Time 09:59PM | Arrival Time 09:00PM | Duration 23h01 | Departure days Thu | Cheapest price $128 |
Operator FlixBus | Departure Time 10:59PM | Arrival Time 10:00PM | Duration 23h01 | Departure days Thu, Sun | Cheapest price $98 |
Operator FlixBus | Departure Time 11:59PM | Arrival Time 11:00PM | Duration 23h01 | Departure days Fri, Sat | Cheapest price $111 |
The table below shows live departures for Brno to Rome buses for today, Monday, November 2. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 8:15 AM Brno | 27h00 | 11:15 AM Rome | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Buses from Brno to Rome with FlixBus. Overnight buses available on this route with FlixBus. Use the details below to compare onboard facilities.
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
Discover the best of Rome — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Rome trip today.
World-famous papal museums with the Sistine Chapel, Raphael Rooms, and major classical collections.
Outstanding ancient sculpture and mosaic museum housed in the Palazzo dei Conservatori and Palazzo Nuovo.
Celebrated villa museum with Bernini sculptures, Caravaggio paintings, and refined garden setting.
Elegant Baroque square with Bernini's fountains, lively atmosphere, and superb people-watching.
Historic square and gathering place at the Spanish Steps, ideal for classic city views and strolls.
Charming cobbled neighborhood filled with ivy-clad lanes, churches, nightlife, and local character.
Classic Roman pasta with guanciale, egg yolk, Pecorino Romano, and black pepper. A city icon known for rich flavor without cream.
Roman pasta with guanciale, tomato, and Pecorino Romano. A traditional Lazio staple tied to shepherd cooking and bold savory flavor.
Pasta with guanciale, Pecorino Romano, and black pepper. Considered one of Rome's oldest pasta dishes and prized for its simplicity.
Three-Michelin-star dining by Niko Romito at Bulgari Hotel Roma, offering refined Italian tasting menus in an elegant setting.
Historic trattoria in Testaccio known for classic Roman pasta and quinto quarto dishes in a lively, traditional setting.
Popular casual spot famed for Roman-style pizzas and fried starters. Bustling atmosphere and a long-standing local reputation.
Moderate for Europe: stays in central Rome are pricey, but transit is cheap and meals range from affordable pizza to costly tourist-area dining.
Service may be included via coperto or servizio. Round up or leave 5-10% at restaurants if service is good; round up in taxis; small change is fine at cafés.
Official public transport app
Via Marsala, Rome -> Piazza Barberini, Rome
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Rome.
Find answers to the most common questions about traveling from Brno to Rome by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Rome, this guide helps you travel smarter and with confidence.

Most Brno to Rome buses use the Brno, Benešova - Grandhotel (Hlavní nádraží) to Roma, Autostazione Tiburtina station pair, with some services arriving at Roma, Autostazione (Metro Anagnina). Use this guide to compare Brno and Rome bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Brno, Benešova - Grandhotel (Hlavní nádraží) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, and Ticket Office.
Free Wi-Fi. ATMs are located inside the station.
Ticket office support is available at Brno, Benešova - Grandhotel (Hlavní nádraží).
Available at Brno, Benešova - Grandhotel (Hlavní nádraží): Parking, Taxis, WC.
Accessibility facilities are available at Brno, Benešova - Grandhotel (Hlavní nádraží): Elevators, ramps.
Roma, Autostazione Tiburtina is 4 km from Rome city centre. Public transport options include:
Roma, Autostazione Tiburtina has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Cafes and vending machines available.
Wi-Fi is available at Roma, Autostazione Tiburtina. ATMs are aTM available near ticket office.
Ticket office support is available at Roma, Autostazione Tiburtina.
Available at Roma, Autostazione Tiburtina: Parking, Taxis, WC.
Accessibility facilities are available at Roma, Autostazione Tiburtina: Wheelchair accessible entrances and facilities.
Check bus stations information for Brno and Rome, including where buses depart and arrive on this route.