- Must visit
Brewery Museum
Modern interactive brewery museum in a 15th-century malt house, explaining beer-making history and daily life in old Plzeň.
Cheapest price
€12
Average price
€23
Fastest journey
3 h 50 m
Average duration
4 h 27 m
Buses per day
7
Distance
241 km
The best way to find a cheap bus ticket from Brno to Plzeň is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Brno to Plzeň will cost around €23 if you buy it on the day, but the cheapest tickets can be found for only €12.
Of the 7 buses that leave Brno for Plzeň on Wed, Aug 26, 3 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Wed, Aug 26 the direct buses cover the 241 km distance in an average of 4 h 27 m but if you time it right, some buses will get you there in just 3 h 50 m .
On Wed, Aug 26 the slowest buses will take 5 h 30 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
FlixBus
000217
000217
FlixBus · FlixBus
FlixBus · FlixBus
000217
000217
FlixBus
FlixBus · FlixBus
FlixBus · FlixBusOmio recommends booking the bus as it is the most popular option from Brno to Plzeň among Omio's users. If you are prioritising price take the bus with prices starting from €4. For those with little time consider booking a bus which can get you there in 4h 21m. The ticket price range depends on the travel mode: a bus costs an average of €4, and a train costs an average of €13.
Distance: 149 miles (241 km)
Most popular Bus | Train | Driving |
|---|---|---|
€19 Average price Cheapest | €23 Average price | €58 Average price (fuel + tolls) |
4h 51m Average total duration Fastest 4h 21m Onboard + 30m Additional time* | 4h 57m Average total duration 4h 27m Onboard + 30m Additional time* | 3h 9m Average total duration (door-to-door) |
![]() Most popular bus company | ![]() Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Brno to Plzeň:
A bus is €4 less than a train for this route with tickets for a train from Brno to Plzeň costing on average €23.
Other travel options to Plzeň take longer:
Train takes on average 4h 27m.
Tickets start at around €19 compared to roughly €58 in fuel and tolls — a saving of about €39. The journey takes 4h 21m versus 3h 9m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by FlixBus, A-Express, Slovak Lines Express a.s., LeviTour, Slovak Lines Express.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator A-Express | Departure Time 02:15AM | Arrival Time 06:05AM | Duration 3h50 | Departure days Tue, Wed, Thu, Fri | Cheapest price €22 |
Operator FlixBus | Departure Time 04:25AM | Arrival Time 11:15AM | Duration 6h50 | Departure days Mon | Cheapest price €8 |
Operator FlixBus | Departure Time 06:40AM | Arrival Time 12:15PM | Duration 5h35 | Departure days Tue, Wed, Thu, Fri | Cheapest price €24 |
Operator FlixBus | Departure Time 12:40PM | Arrival Time 05:35PM | Duration 4h55 | Departure days Sat, Sun | Cheapest price €12 |
Operator FlixBus | Departure Time 02:40PM | Arrival Time 07:35PM | Duration 4h55 | Departure days Tue, Thu, Fri | Cheapest price €12 |
Operator FlixBus | Departure Time 04:10PM | Arrival Time 09:50PM | Duration 5h40 | Departure days Mon, Wed, Sat | Cheapest price €13 |
Operator FlixBus | Departure Time 05:10PM | Arrival Time 10:50PM | Duration 5h40 | Departure days Mon, Sat, Sun | Cheapest price €9 |
Operator FlixBus | Departure Time 06:10PM | Arrival Time 12:15AM | Duration 6h05 | Departure days Mon, Tue, Wed, Thu, Fri | Cheapest price €7 |
Operator FlixBus | Departure Time 08:10PM | Arrival Time 01:15AM | Duration 5h05 | Departure days Tue, Wed, Thu, Fri | Cheapest price €23 |
Operator FlixBus | Departure Time 09:59PM | Arrival Time 01:55AM | Duration 3h56 | Departure days Sun | Cheapest price €17 |
Operator FlixBus | Departure Time 10:59PM | Arrival Time 02:55AM | Duration 3h56 | Departure days Sun | Cheapest price €17 |
Operator FlixBus | Departure Time 11:59PM | Arrival Time 03:55AM | Duration 3h56 | Departure days Tue, Wed, Thu, Fri | Cheapest price €12 |
The table below shows live departures for Brno to Plzeň buses for today, Tuesday, August 25. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus | 2:40 PM Brno, Benešova - Grandhotel (Hlavní nádraží) | 4h55 | 7:35 PM Plzeň, Centrální Autobusové Nádraží | 0 transfersDirect | |
FlixBus | 2:40 PM Brno, Benešova - Grandhotel (Hlavní nádraží) | 4h50 | 7:30 PM Plzeň, Divadlo Alfa | 0 transfersDirect | |
FlixBus · FlixBus | 6:10 PM Brno, Benešova - Grandhotel (Hlavní nádraží) | 5h40 | 11:50 PM Plzeň, Centrální Autobusové Nádraží | 1 transfer | |
FlixBus · FlixBus | 8:10 PM Brno, Benešova - Grandhotel (Hlavní nádraží) | 5h05 | 1:15 AM Plzeň, Centrální Autobusové Nádraží | 1 transfer | |
FlixBus | 11:59 PM Brno, Benešova - Grandhotel (Hlavní nádraží) | 3h56 | 3:55 AM Plzeň, Centrální Autobusové Nádraží | 0 transfersDirect | |
000217 | 2:15 AM Brno, Benešova - Grandhotel (Hlavní nádraží) | 3h55 | 6:10 AM Plzeň, Centrální Autobusové Nádraží | 0 transfersDirect | |
000217 | 2:15 AM Brno, Benešova - Grandhotel (Hlavní nádraží) | 3h50 | 6:05 AM Plzeň, Divadlo Alfa | 0 transfersDirect | |
FlixBus · FlixBus | 6:40 AM Brno, Benešova - Grandhotel (Hlavní nádraží) | 5h35 | 12:15 PM Plzeň, Centrální Autobusové Nádraží | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Brno to Plzeň run on average 7 times per day, taking around 4h 21m. Cheap bus tickets for this journey start at €4 if you book in advance.
There are 5 buses per day. The earliest bus runs at 01:05, the last at 23:55. The fastest bus covers the 149 miles (241 km) distance in 3h 50m.
Distance 149 miles (241 km) |
Average bus duration 4h 21m |
Cheapest ticket price €4 |
Buses per day 7 |
Direct buses 5 |
Fastest bus 3h 50m |
First bus 1:05 AM |
Last bus 11:55 PM |
Cheapest Month May |
Cheapest Day Tue |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Thu |
Least Busy Day Tue |
Best time to book 21 days |
Discover the best of Plzeň — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Plzeň trip today.
Modern interactive brewery museum in a 15th-century malt house, explaining beer-making history and daily life in old Plzeň.
Major regional museum with archaeology, applied arts, weapons and civic history, housed in a remarkable historic building.
Popular puppetry museum in the old town presenting Czech marionette traditions, stagecraft and family-friendly exhibits.
Plzeň’s main square, lined with major monuments and colorful facades. The essential starting point for exploring the historic center.
Historic pedestrian street linking the station area with the center, valued for architecture, shops and an everyday city atmosphere.
Large urban park with mature trees, paths and open lawns. A favorite local place for walks close to the old town.
Bottom-fermented pale lager first brewed in Plzeň in 1842. Its soft water, Saaz hops, and triple decoction made the city world-famous.
Crisp fried cheese, usually Edam, served with tartar sauce and potatoes. A classic Czech pub meal commonly eaten in Plzeň.
Beef goulash slow-cooked with onions and paprika, often served with bread dumplings. A staple in Czech beer halls across Plzeň.
Refined fine dining with seasonal tasting menus, polished service, and a modern setting inside Hotel Rous.
Historic brewery restaurant beside Pilsner Urquell. Best for unfiltered tank beer and classic Czech dishes in a lively traditional setting.
Traditional Plzeň beer hall known for Pilsner Urquell, hearty Czech meals, and a classic local pub atmosphere.
Moderate for Czech city travel: hotels, dining, and transit are usually cheaper than Prague, but tourist areas and brewery venues can cost more.
Tip about 5-10% in restaurants if service is good, often by rounding up. Round up small taxi fares. In cafes, small change or rounding up is common.
Official public transport app
Plzeň, Centrální Autobusové Nádraží -> Náměstí Republiky, Plzeň
Find answers to the most common questions about traveling from Brno to Plzeň by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Plzeň, this guide helps you travel smarter and with confidence.

Most Brno to Plzeň buses use the Brno, Benešova - Grandhotel (Hlavní nádraží) to Plzeň, Centrální Autobusové Nádraží station pair, with some services arriving at Plzeň, Divadlo Alfa. Use this guide to compare Brno and Plzeň bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Brno, Benešova - Grandhotel (Hlavní nádraží) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, and Ticket Office.
Free Wi-Fi. ATMs are located inside the station.
Ticket office support is available at Brno, Benešova - Grandhotel (Hlavní nádraží).
Available at Brno, Benešova - Grandhotel (Hlavní nádraží): Parking, Taxis, WC.
Accessibility facilities are available at Brno, Benešova - Grandhotel (Hlavní nádraží): Elevators, ramps.
Plzeň, Divadlo Alfa is 1 km from Plzeň city centre. Public transport options include:
Plzeň, Divadlo Alfa has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Plzeň, Divadlo Alfa. ATMs are available at Plzeň, Divadlo Alfa.
Ticket office support is available at Plzeň, Divadlo Alfa.
Available at Plzeň, Divadlo Alfa: Parking, Taxis, WC.
Accessibility facilities are available at Plzeň, Divadlo Alfa: Wheelchair accessible paths.
Plzen, Centralni Autobusove Nadrazi is 5 km from Plzeň city centre. Public transport options include:
Plzen, Centralni Autobusove Nadrazi has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Snack bars available.
Wi-Fi is available at Plzen, Centralni Autobusove Nadrazi. ATMs are aTM available near the main entrance.
Ticket office support is available at Plzen, Centralni Autobusove Nadrazi.
Available at Plzen, Centralni Autobusove Nadrazi: Parking, Taxis, WC.
Accessibility facilities are available at Plzen, Centralni Autobusove Nadrazi: Accessible for passengers with reduced mobility.
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