- Must visit
Brewery Museum
Modern interactive brewery museum in a 15th-century malt house, explaining beer-making history and daily life in old Plzeň.
Cheapest price on Oct 10
$11
Average ticket price on Oct 10
$14
Fastest journey on Oct 10
4 h 55 m
Average journey duration on Oct 10
5 h 25 m
Buses on Oct 10
3
Distance
241 km
The best way to find a cheap bus ticket from Brno to Plzeň is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Brno to Plzeň will cost around $14 if you buy it on the day, but the cheapest tickets can be found for only $11.
On Sat, Oct 10, we found 3 buses from Brno to Plzeň, including 3 direct services.
On Sat, Oct 10 the direct buses cover the 241 km distance in an average of 5 h 25 m but if you time it right, some buses will get you there in just 4 h 55 m .
On Sat, Oct 10 the slowest buses will take 5 h 40 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.






Buses from Brno to Plzeň run on average 7 times per day, taking around 4h 20m. Cheap bus tickets for this journey start at $5 if you book in advance.
There are 5 buses per day. The earliest bus runs at 01:05, the last at 23:55. The fastest bus covers the 149 miles (241 km) distance in 3h 50m.
Distance 149 miles (241 km) |
Average bus duration 4h 20m |
Cheapest ticket price $5 |
Buses per day 7 |
Direct buses 5 |
Fastest bus 3h 50m |
First bus 1:05 AM |
Last bus 11:55 PM |
Cheapest Month May |
Cheapest Day Tue |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Fri |
Least Busy Day Tue |
Best time to book 1 day |
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator A-Express | Departure Time 02:15AM | Arrival Time 06:05AM | Duration 3h50 | Departure days Wed, Fri | Cheapest price $26 |
Operator FlixBus | Departure Time 04:25AM | Arrival Time 11:15AM | Duration 6h50 | Departure days Mon | Cheapest price $10 |
Operator FlixBus | Departure Time 06:40AM | Arrival Time 12:15PM | Duration 5h35 | Departure days Wed, Fri, Sun | Cheapest price $15 |
Operator FlixBus | Departure Time 12:40PM | Arrival Time 05:35PM | Duration 4h55 | Departure days Thu, Sat | Cheapest price $15 |
Operator FlixBus | Departure Time 02:40PM | Arrival Time 08:40PM | Duration 6h00 | Departure days Tue, Fri, Sun | Cheapest price $14 |
Operator FlixBus | Departure Time 04:10PM | Arrival Time 09:50PM | Duration 5h40 | Departure days Mon, Tue, Wed, Thu, Sat | Cheapest price $13 |
Operator FlixBus | Departure Time 05:10PM | Arrival Time 10:50PM | Duration 5h40 | Departure days Mon, Tue, Thu, Sat | Cheapest price $7 |
Operator FlixBus | Departure Time 06:10PM | Arrival Time 12:15AM | Duration 6h05 | Departure days Mon, Wed, Fri, Sun | Cheapest price $8 |
Operator FlixBus | Departure Time 07:10PM | Arrival Time 12:20AM | Duration 5h10 | Departure days Sun | Cheapest price $26 |
Operator FlixBus | Departure Time 08:10PM | Arrival Time 01:15AM | Duration 5h05 | Departure days Wed, Fri, Sun | Cheapest price $15 |
Operator FlixBus | Departure Time 11:59PM | Arrival Time 03:55AM | Duration 3h56 | Departure days Wed, Fri, Sun | Cheapest price $14 |
The table below shows live departures for Brno to Plzeň buses for today, Friday, October 9. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus | 2:40 PM Brno, Benešova - Grandhotel (Hlavní nádraží) | 4h50 | 7:30 PM Plzeň, Divadlo Alfa | 0 transfersDirect | |
FlixBus | 2:40 PM Brno, Benešova - Grandhotel (Hlavní nádraží) | 4h55 | 7:35 PM Plzeň, Centrální Autobusové Nádraží | 0 transfersDirect | |
FlixBus · FlixBus | 6:10 PM Brno, Benešova - Grandhotel (Hlavní nádraží) | 5h40 | 11:50 PM Plzeň, Centrální Autobusové Nádraží | 1 transfer | |
FlixBus · FlixBus | 8:10 PM Brno, Benešova - Grandhotel (Hlavní nádraží) | 5h05 | 1:15 AM Plzeň, Centrální Autobusové Nádraží | 1 transfer | |
FlixBus | 11:59 PM Brno, Benešova - Grandhotel (Hlavní nádraží) | 3h56 | 3:55 AM Plzeň, Centrální Autobusové Nádraží | 0 transfersDirect |
Find all the dates and times for this journey
Discover the best of Plzeň — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Plzeň trip today.
Modern interactive brewery museum in a 15th-century malt house, explaining beer-making history and daily life in old Plzeň.
Major regional museum with archaeology, applied arts, weapons and civic history, housed in a remarkable historic building.
Popular puppetry museum in the old town presenting Czech marionette traditions, stagecraft and family-friendly exhibits.
Plzeň’s main square, lined with major monuments and colorful facades. The essential starting point for exploring the historic center.
Historic pedestrian street linking the station area with the center, valued for architecture, shops and an everyday city atmosphere.
Large urban park with mature trees, paths and open lawns. A favorite local place for walks close to the old town.
Bottom-fermented pale lager first brewed in Plzeň in 1842. Its soft water, Saaz hops, and triple decoction made the city world-famous.
Crisp fried cheese, usually Edam, served with tartar sauce and potatoes. A classic Czech pub meal commonly eaten in Plzeň.
Beef goulash slow-cooked with onions and paprika, often served with bread dumplings. A staple in Czech beer halls across Plzeň.
Refined fine dining with seasonal tasting menus, polished service, and a modern setting inside Hotel Rous.
Historic brewery restaurant beside Pilsner Urquell. Best for unfiltered tank beer and classic Czech dishes in a lively traditional setting.
Traditional Plzeň beer hall known for Pilsner Urquell, hearty Czech meals, and a classic local pub atmosphere.
Moderate for Czech city travel: hotels, dining, and transit are usually cheaper than Prague, but tourist areas and brewery venues can cost more.
Tip about 5-10% in restaurants if service is good, often by rounding up. Round up small taxi fares. In cafes, small change or rounding up is common.
Official public transport app
Plzeň, Centrální Autobusové Nádraží -> Náměstí Republiky, Plzeň
Find answers to the most common questions about traveling from Brno to Plzeň by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Plzeň, this guide helps you travel smarter and with confidence.

Most Brno to Plzeň buses use the Brno, Benešova - Grandhotel (Hlavní nádraží) to Plzeň, Centrální Autobusové Nádraží station pair, with some services arriving at Plzeň, Divadlo Alfa. Use this guide to compare Brno and Plzeň bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Brno, Benešova - Grandhotel (Hlavní nádraží) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, and Ticket Office.
Free Wi-Fi. ATMs are located inside the station.
Ticket office support is available at Brno, Benešova - Grandhotel (Hlavní nádraží).
Available at Brno, Benešova - Grandhotel (Hlavní nádraží): Parking, Taxis, WC.
Accessibility facilities are available at Brno, Benešova - Grandhotel (Hlavní nádraží): Elevators, ramps.
Plzeň, Divadlo Alfa is 1 km from Plzeň city centre. Public transport options include:
Plzeň, Divadlo Alfa has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Plzeň, Divadlo Alfa. ATMs are available at Plzeň, Divadlo Alfa.
Ticket office support is available at Plzeň, Divadlo Alfa.
Available at Plzeň, Divadlo Alfa: Parking, Taxis, WC.
Accessibility facilities are available at Plzeň, Divadlo Alfa: Wheelchair accessible paths.
Plzen, Centralni Autobusove Nadrazi is 5 km from Plzeň city centre. Public transport options include:
Plzen, Centralni Autobusove Nadrazi has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Snack bars available.
Wi-Fi is available at Plzen, Centralni Autobusove Nadrazi. ATMs are aTM available near the main entrance.
Ticket office support is available at Plzen, Centralni Autobusove Nadrazi.
Available at Plzen, Centralni Autobusove Nadrazi: Parking, Taxis, WC.
Accessibility facilities are available at Plzen, Centralni Autobusove Nadrazi: Accessible for passengers with reduced mobility.
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