- Must visit
Pilsner Urquell Brewery Visitor Center
Museum-style brewery experience covering the history of Pilsner beer, historic cellars, and brewing heritage. One of the city’s signature visitor attractions.






Cheapest price
$15
Average price
$20
Fastest journey
3h 56m
Average duration
4h 52m
Buses per day
6
Distance
243 km
Omio recommends booking the bus as it is the most popular option from Brno to Plzeň among Omio's users. If you are prioritising price take the bus with prices starting from $6. For those with little time consider booking a bus which can get you there in 4h 11m. The ticket price range depends on the travel mode: a bus costs an average of $6, and a train costs an average of $12.
Distance: 149 miles (241 km)
Most popular Bus | Train | Driving |
|---|---|---|
$14 Average price Cheapest | $26 Average price | $70 Average price (fuel + tolls) |
4h 41m Average total duration Fastest 4h 11m Onboard + 30m Additional time* | 5h 1m Average total duration 4h 31m Onboard + 30m Additional time* | 3h 9m Average total duration (door-to-door) |
![]() Most popular bus company | ![]() Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Brno to Plzeň:
A bus is $11 (€9) less than a train for this route with tickets for a train from Brno to Plzeň costing on average $26 (€21).
Other travel options to Plzeň take longer:
Train takes on average 4h 31m.
Tickets start at around $14 (€12) compared to roughly $70 (€57) in fuel and tolls — a saving of about $56 (€46). The journey takes 4h 11m versus 3h 9m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by FlixBus, A-Express, Slovak Lines Express a.s., Slovak Lines Express.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator A-Express | Departure Time 02:15AM | Arrival Time 06:10AM | Duration 3h55 | Departure days Mon, Tue, Wed, Thu, Fri, Sun | Cheapest price $25 |
Operator FlixBus | Departure Time 06:40AM | Arrival Time 12:15PM | Duration 5h35 | Departure days Mon, Tue, Wed, Thu, Fri, Sun | Cheapest price $24 |
Operator FlixBus | Departure Time 12:40PM | Arrival Time 05:35PM | Duration 4h55 | Departure days Sat | Cheapest price $15 |
Operator LeviTour | Departure Time 02:35PM | Arrival Time 07:20PM | Duration 4h45 | Departure days Mon, Tue, Wed, Thu, Fri, Sun | Cheapest price $24 |
Operator FlixBus | Departure Time 02:40PM | Arrival Time 07:30PM | Duration 4h50 | Departure days Mon, Thu, Fri, Sun | Cheapest price $15 |
Operator FlixBus | Departure Time 04:10PM | Arrival Time 09:50PM | Duration 5h40 | Departure days Tue, Wed, Sat | Cheapest price $17 |
Operator FlixBus | Departure Time 05:10PM | Arrival Time 10:50PM | Duration 5h40 | Departure days Sat | Cheapest price $12 |
Operator FlixBus | Departure Time 06:10PM | Arrival Time 11:50PM | Duration 5h40 | Departure days Mon, Tue, Wed, Thu, Fri, Sun | Cheapest price $21 |
Operator FlixBus | Departure Time 07:10PM | Arrival Time 12:20AM | Duration 5h10 | Departure days Sun | Cheapest price $33 |
Operator FlixBus | Departure Time 08:10PM | Arrival Time 01:15AM | Duration 5h05 | Departure days Mon, Tue, Wed, Thu, Fri, Sun | Cheapest price $22 |
Operator FlixBus | Departure Time 11:59PM | Arrival Time 03:55AM | Duration 3h56 | Departure days Mon, Tue, Wed, Thu, Fri, Sun | Cheapest price $15 |
The table below shows live departures for Brno to Plzeň buses for today, Thursday, July 9. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
609802 | 2:35 PM Brno, ÚAN Zvonařka | 4h45 | 7:20 PM Plzeň, Centrální Autobusové Nádraží | 0 transfersDirect | |
FlixBus | 2:40 PM Brno, Benešova - Grandhotel (Hlavní nádraží) | 4h55 | 7:35 PM Plzeň, Centrální Autobusové Nádraží | 0 transfersDirect | |
FlixBus | 2:40 PM Brno, Benešova - Grandhotel (Hlavní nádraží) | 4h50 | 7:30 PM Plzeň, Divadlo Alfa | 0 transfersDirect | |
FlixBus · FlixBus | 6:10 PM Brno, Benešova - Grandhotel (Hlavní nádraží) | 5h40 | 11:50 PM Plzeň, Centrální Autobusové Nádraží | 1 transfer | |
FlixBus · FlixBus | 8:10 PM Brno, Benešova - Grandhotel (Hlavní nádraží) | 5h05 | 1:15 AM Plzeň, Centrální Autobusové Nádraží | 1 transfer | |
FlixBus | 11:59 PM Brno, Benešova - Grandhotel (Hlavní nádraží) | 3h56 | 3:55 AM Plzeň, Centrální Autobusové Nádraží | 0 transfersDirect | |
| Friday, July 10 | |||||
000217 | 2:15 AM Brno, Benešova - Grandhotel (Hlavní nádraží) | 3h50 | 6:05 AM Plzeň, Divadlo Alfa | 0 transfersDirect | |
000217 | 2:15 AM Brno, Benešova - Grandhotel (Hlavní nádraží) | 3h55 | 6:10 AM Plzeň, Centrální Autobusové Nádraží | 0 transfersDirect | |
FlixBus · FlixBus | 6:40 AM Brno, Benešova - Grandhotel (Hlavní nádraží) | 5h35 | 12:15 PM Plzeň, Centrální Autobusové Nádraží | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Brno to Plzeň run on average 7 times per day, taking around 4h 11m. Cheap bus tickets for this journey start at $6 (€5) if you book in advance.
There are 5 buses per day. The earliest bus runs at 01:05, the last at 23:55. The fastest bus covers the 149 miles (241 km) distance in 3h 56m.
Distance 149 miles (241 km) |
Average bus duration 4h 11m |
Cheapest ticket price $6 (€5) |
Buses per day 7 |
Direct buses 5 |
Fastest bus 3h 56m |
First bus 1:05 AM |
Last bus 11:55 PM |
Cheapest Month May |
Cheapest Day Mon |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Thu |
Least Busy Day Wed |
Best time to book 21 days |
Discover the best of Plzeň — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Plzeň trip today.
Museum-style brewery experience covering the history of Pilsner beer, historic cellars, and brewing heritage. One of the city’s signature visitor attractions.
The city’s main regional museum with archaeology, applied arts, arms, and cultural history collections. A strong introduction to West Bohemia’s heritage.
Small museum dedicated to the liberation of Plzeň by the U.S. Army in 1945, with vehicles, uniforms, and wartime memorabilia.
The main square of Plzeň and the natural starting point for visitors, lined with major monuments and civic buildings.
The compact old town area around the main square, best explored on foot for Gothic, Renaissance, and Baroque architecture.
Central tree-lined promenade and park belt near the old town, useful for strolling between landmarks and cultural venues.
The city’s signature bottom-fermented pale lager, first brewed in Plzeň in 1842. It is the original Pilsner style and the most iconic local drink to try fresh in its home city.
Marinated beef sirloin served with a creamy vegetable sauce, bread dumplings, lemon, cranberries, and whipped cream. It is one of the most beloved classic Czech celebratory dishes.
Roast pork with bread dumplings and braised sauerkraut. This is a cornerstone of traditional Czech pub and home cooking, especially satisfying with local beer.
A long-established city-center restaurant with a more refined feel, known for dependable European and Czech cooking in a historic building.
A respected modern Czech restaurant and brewery venue serving polished local dishes and house beer in a stylish but approachable setting.
A large, established restaurant at the Pilsner Urquell brewery complex, known for classic Czech cuisine and fresh tank beer in a historic brewery setting.
Generally cheaper than Prague. Hotels and beer are good value; central dining costs more.
About 10% in restaurants for good service. Round up in cafés and taxis. Tip in cash or tell staff the total before card payment.
Official public transport app
Plzeň, Centrální Autobusové Nádraží, Plzeň -> Plzeň hlavní nádraží, Plzeň
Find answers to the most common questions about traveling from Brno to Plzeň by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Plzeň, this guide helps you travel smarter and with confidence.

Most Brno to Plzeň buses use the Brno, Benešova - Grandhotel (Hlavní nádraží) to Plzeň, Centrální Autobusové Nádraží station pair, with some services arriving at Plzeň, Divadlo Alfa. Use this guide to compare Brno and Plzeň bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Brno, Benešova - Grandhotel (Hlavní nádraží) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, and Ticket Office.
Free Wi-Fi. ATMs are located inside the station.
Ticket office support is available at Brno, Benešova - Grandhotel (Hlavní nádraží).
Available at Brno, Benešova - Grandhotel (Hlavní nádraží): Parking, Taxis, WC.
Accessibility facilities are available at Brno, Benešova - Grandhotel (Hlavní nádraží): Elevators, ramps.
Here are some other resources that might have the information you need