Palermo to Siena bus with FlixBus

Wed, Feb 11
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The cheapest and fastest buses from Palermo to Siena

Showing times and prices for Feb 12

Cheapest price

$53

Average price

$68

Fastest journey

16 h 20 m

Average duration

17 h 38 m

Buses per day

2

Distance

603 km

Cheap tickets

The best way to find a cheap bus ticket from Palermo to Siena is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Palermo to Siena will cost around $68 if you buy it on the day, but the cheapest tickets can be found for only $53.

Fast buses

Of the 2 buses that leave Palermo for Siena on Thu, Feb 12, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.

On Thu, Feb 12 the direct buses cover the 603 km distance in an average of 17 h 38 m but if you time it right, some buses will get you there in just 16 h 20 m .

On Thu, Feb 12 the slowest buses will take 18 h 55 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

FlixBus
09:10AM18h55
Palermo
04:05AMSiena
$531One-way
0 transfers
FlixBus
01:25PM16h20
Palermo
05:45AMSiena
$841One-way
0 transfers

Travel Information

Compare bus, train, flight, and ferry for Palermo to Siena

Omio recommends booking the bus as it is the most popular option from Palermo to Siena among Omio's users. If you are prioritising price take the ferry with prices starting from €48. For those with little time consider booking a flight which can get you there in 1h 23m. The ticket price range depends on the travel mode: a ferry costs an average of €48, and a flight costs an average of €17.

Distance: 374 miles (603 km)

Compare bus with

Most popular
Bus
Flight
Train
Ferry

€60

Average price

€137

Average price

€106

Average price

€55

Average price

Cheapest

17h 1m

Average total duration

16h 31m

Onboard

+

30m

Additional time*

4h 23m

Average total duration

Fastest

1h 23m

Onboard

+

3h 0m

Additional time*

15h 2m

Average total duration

14h 32m

Onboard

+

30m

Additional time*

20h 49m

Average total duration

19h 49m

Onboard

+

1h 0m

Additional time*

Direct Options

Direct Options

Direct Options

Direct Options

Palermo to Siena Bus Timetables

OperatorDeparture TimeArrival TimeDurationDeparture daysCheapest price
Operator
FlixBus
Departure Time
03:25PM
Arrival Time
07:45AM
Duration
16h20
Departure days
Sat
Cheapest price
$41
Operator
FlixBus
Departure Time
05:20PM
Arrival Time
11:25AM
Duration
18h05
Departure days
Sat
Cheapest price
$61

Live departures

Palermo to Siena bus times

The table below shows live departures for Palermo to Siena buses for today, Wednesday, February 11. You can also manually refresh the results below to see updated bus journeys.

Last updated at 7:28 AM
ProviderDepartsDurationArrivesTransfers
Tickets
meinfernbus_flixbus1:25 PM Palermo
16h20
5:45 AM Siena0 transfersDirect

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets Palermo to Siena by bus, train, flight, or ferry

Compare bus, train, flight, and ferry prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Thu
Feb 12
Fri
Feb 13
Sat
Feb 14
Sun
Feb 15
Mon
Feb 16
Tue
Feb 17
Wed
Feb 18

Why should you book Palermo to Siena buses with Omio?

FlixBus as well as Itabus offer buses services from Palermo to Siena.
Omio is an official ticket reseller for all your travel options from Palermo to Siena.

Why book with Omio vs FlixBus?

  • Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of Itabus to find the best option for your trip from Palermo to Siena.
  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are bus, train, flight and ferry to ensure you get the best deal for traveling from Palermo to Siena.

Why book with Omio over Wanderu or Checkmybus?

  • Compare with other providers: On Omio, you can also compare tickets for the likes of Itabus to find the best option for your trip from Palermo to Siena.
  • Multiple modes of transport: Omio allows you to compare travel options including bus, train, flight and ferry to find the ideal travel option from Palermo to Siena.

Journey information

Overview: Bus from Palermo to Siena

ItalyItaly
ItalyItaly
Icon of bus

Buses from Palermo to Siena run on average 4 times per day, taking around 16h 31m. Cheap bus tickets for this journey start at $35 (€28) but you can travel from only $22 (€17) by flight.

There are 1 buses per day. The earliest bus runs at 05:00, the last at 22:25. The fastest bus covers the 374 miles (603 km) distance in 16h 20m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $22 (€17)
Distance
374 miles (603 km)
Average bus duration
16h 31m
Cheapest ticket price
$35 (€28)
Buses per day
4
Direct buses
1
Fastest bus
16h 20m
First bus
05:00
Last bus
22:25
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $22 (€17)

Bus providers: FlixBus, Itabus from Palermo to SienaYou can travel by bus between Palermo to Siena with FlixBus, Itabus for as low as $22 (€17). When you search for schedules and tickets, Omio will show you the best journey

FlixBus

About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
16h 20m
Cheapest Price
$52 (€41)
FlixBus frequency
5 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.

Itabus

About
Itabus is a leading bus company in Italy, providing reliable and comfortable transportation services to its customers. Itabus operates a fleet of modern buses, ranging from luxury coaches to standard buses, all equipped with air conditioning, comfortable seating, and onboard entertainment.
Luggage & cancellation policy
Average Duration
18h 35m
Cheapest Price
$29 (€23)
Itabus frequency
1 a day
Luggage included
One carry-on bag up to 10kg and one checked bag up to 20kg.
Additional luggage
5€ per additional bag.
Cancellation Policy
You can cancel your ticket up to 24 hours before departure for a partial refund. Changes allowed for a fee.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Dedicated seating areas; Accessible restrooms.
Bikes
Bikes are allowed.
Pets
Small pets allowed in carriers; larger pets must be leashed and muzzled.

FAQs: Bus from Palermo to Siena

Find answers to the most common questions about traveling from Palermo to Siena by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Siena, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Palermo to Siena can start from as little as $35 (€28) when you book in advance. The average bus ticket price for Palermo to Siena is $76 (€60) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Palermo to Siena is 16h 20m to travel the 374 miles (603 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Palermo to Siena leaves at 5:00 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Palermo to Siena leaves at 10:25 PM.
Yes, there are 1 direct buses a day from Palermo to Siena with FlixBus. Schedules can vary on holidays or weekends with fewer direct buses.
When taking a bus from Palermo to Siena, you can count on FlixBus, Itabus for the best way to get you to Siena. You can also check all possible bus companies who offer a service between Palermo and Siena and compare the amenities they offer before buying a bus ticket.
A trip to Siena from Palermo is worth doing but not as a day trip with a journey time of 16h 20m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Palermo to Siena is May.
It's helpful to compare your options as there are 4 ways to travel between Palermo and Siena including taking a bus, train, flight, and ferry.
Yes, the following accessibility options are available when taking the bus from Palermo to Siena:
  • FlixBus
    • Assistance
    • Priority boarding
    • Wheelchair-accessible buses.
  • Itabus
    • Assistance
    • Dedicated seating areas
    • Accessible restrooms.
Yes, there are bathrooms on board the bus from Palermo to Siena for bus company FlixBus, Itabus.
Some of the most interesting sights to explore in Siena are:
  • Piazza del Campo, a shell-shaped medieval square known for hosting the Palio horse race and surrounded by historic buildings
  • Siena Cathedral, a stunning example of Italian Romanesque-Gothic architecture featuring intricate marble work and art by famous masters
  • Palazzo Pubblico, a Gothic town hall with the Torre del Mangia offering panoramic views of the city
  • Basilica of San Domenico, a large church housing relics of Saint Catherine of Siena and notable frescoes
  • Santa Maria della Scala, a former hospital turned museum complex showcasing art and history exhibitions.
The best things to do in Siena include:
  • Torre del Mangia, a tall tower offering panoramic views of the city and surrounding countryside
  • Museo dell'Opera del Duomo, a museum housing an impressive collection of religious art and artifacts
  • Fortezza Medicea, a historic fortress offering beautiful views and a peaceful park for relaxation
  • Enoteca Italiana, a wine museum and tasting center where you can explore and enjoy Italian wines
  • Take a cooking class to learn how to make traditional Tuscan dishes.
Whether you can cancel your bus ticket from Palermo to Siena depends on the bus companies:
  • FlixBus
    • You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
  • Itabus
    • You can cancel your ticket up to 24 hours before departure for a partial refund. Changes allowed for a fee.
Yes, bikes are allowed on board the bus with bus company FlixBus, Itabus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Palermo to Siena.
Yes, the following luggage options are included when booking a bus ticket from Palermo to Siena:
  • FlixBus
    • One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
  • Itabus
    • One carry-on bag up to 10kg and one checked bag up to 20kg.
Yes, the following additional luggage options are available when booking a bus ticket from Palermo to Siena:
  • FlixBus
    • Additional luggage can be purchased for a fee.
  • Itabus
    • 5€ per additional bag.
Yes, you can bring your pet on the bus from Palermo to Siena. The following conditions apply:
  • FlixBus
    • Small pets in carriers allowed
    • guide dogs travel for free.
  • Itabus
    • Small pets allowed in carriers
    • larger pets must be leashed and muzzled.
You can reserve your seat on the bus from Palermo to Siena with the following bus company: FlixBus, Itabus
Yes, there are USB plugs on board the bus from Palermo to Siena with the following bus company: FlixBus, Itabus.
Yes, there is Wifi on board the bus from Palermo to Siena with the following bus company: FlixBus, Itabus.

popular bus stations

Popular bus stations from Palermo to Siena

Palermo
Siena
Siena, Stazione FS (Piazzale Carlo Rosselli)
information
Siena, Siena/Viale Pietro Toselli
information
Siena, P.za Gramsc
information

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