Palermo to Siena bus with FlixBus

Thu, Nov 13
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FlixBus
Itabus
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Rede Expressos
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FlixBus
Itabus
Alsa
BlaBlaCar Bus
Rede Expressos
1,000+ travel companies
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The cheapest and fastest buses from Palermo to Siena

Showing times and prices for Nov 13

Cheapest price

$52

Average price

$67

Fastest journey

16 h 20 m

Average duration

17 h 38 m

Buses per day

2

Distance

603 km

Cheap tickets

The best way to find a cheap bus ticket from Palermo to Siena is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Palermo to Siena will cost around $67 if you buy it on the day, but the cheapest tickets can be found for only $52.

Fast buses

Of the 2 buses that leave Palermo for Siena on Thu, Nov 13, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.

On Thu, Nov 13 the direct buses cover the 603 km distance in an average of 17 h 38 m but if you time it right, some buses will get you there in just 16 h 20 m .

On Thu, Nov 13 the slowest buses will take 18 h 55 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

FlixBus
09:10AM18h55
Palermo
04:05AMSiena
$521One-way
0 transfers
FlixBus
01:25PM16h20
Palermo
05:45AMSiena
$811One-way
0 transfers

Travel Information

Compare train, bus, flight, and ferry for Palermo to Siena

Omio recommends booking the bus as it is the most popular option from Palermo to Siena among Omio's users. If you are prioritising price take the ferry with prices starting from €42. For those with little time consider booking a flight which can get you there in 1h 23m. The ticket price range depends on the travel mode: a ferry costs an average of €42, and a flight costs an average of €25.

Distance: 374 miles (603 km)

Compare bus with

Most popular
Bus
Flight
Train
Ferry

€78

Average price

€131

Average price

€119

Average price

€66

Average price

Cheapest

16h 54m

Average total duration

16h 24m

Onboard

+

30m

Additional time*

4h 23m

Average total duration

Fastest

1h 23m

Onboard

+

3h 0m

Additional time*

15h 2m

Average total duration

14h 32m

Onboard

+

30m

Additional time*

20h 50m

Average total duration

19h 50m

Onboard

+

1h 0m

Additional time*

Direct Options

Direct Options

Direct Options

Direct Options

Live departures

Palermo to Siena bus times

The table below shows live departures for Palermo to Siena buses for tomorrow, Thursday, November 13. You can also manually refresh the results below to see updated bus journeys.

Last updated at 8:57 PM
ProviderDepartsDurationArrivesTransfers
Tickets
meinfernbus_flixbus9:10 AM Palermo
18h55
4:05 AM Siena0 transfersDirect
meinfernbus_flixbus1:25 PM Palermo
16h20
5:45 AM Siena0 transfersDirect

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets Palermo to Siena by train, bus, flight, or ferry

Compare train, bus, flight, and ferry prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Thu
Nov 13
Fri
Nov 14
Sat
Nov 15
Sun
Nov 16
Mon
Nov 17
Tue
Nov 18
Wed
Nov 19

Journey information

Overview: Bus from Palermo to Siena

ItalyItaly
ItalyItaly
Icon of bus
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $31 (€25)
Distance
374 miles (603 km)
Average bus duration
16h 24m
Cheapest ticket price
$47 (€38)
Buses per day
4
Direct buses
1
Fastest bus
16h 20m
First bus
00:05
Last bus
23:39

Key Takeaways

Train Ticket Prices
  • Budget Options: Train tickets from Palermo to Siena start from as low as $47 (€38) if booked well in advance.
  • Standard Fares: Typically, trains cost $96 (€78) depending on the train type and class.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $31 (€25)

Bus providers: FlixBus, Itabus from Palermo to SienaYou can travel by bus between Palermo to Siena with FlixBus, Itabus for as low as $31 (€25). When you search for schedules and tickets, Omio will show you the best journey

FlixBus

About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
16h 20m
Cheapest Price
$51 (€41)
FlixBus frequency
5 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.

Itabus

About
Itabus is a leading bus company in Italy, providing reliable and comfortable transportation services to its customers. Itabus operates a fleet of modern buses, ranging from luxury coaches to standard buses, all equipped with air conditioning, comfortable seating, and onboard entertainment.
Luggage & cancellation policy
Average Duration
18h 35m
Cheapest Price
$28 (€23)
Itabus frequency
1 a day
Luggage included
One carry-on bag up to 10kg and one checked bag up to 20kg.
Additional luggage
5€ per additional bag.
Cancellation Policy
You can cancel your ticket up to 24 hours before departure for a partial refund. Changes allowed for a fee.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Dedicated seating areas; Accessible restrooms.
Bikes
Bikes are allowed.
Pets
Small pets allowed in carriers; larger pets must be leashed and muzzled.

FAQs: Bus from Palermo to Siena

Find answers to the most common questions about traveling from Palermo to Siena by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Siena, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Palermo to Siena can start from as little as $41 (€33) when you book in advance. The average bus ticket price for Palermo to Siena is $77 (€62); however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The bus time between Palermo and Siena is on average 16 h 20 min   for the 374 mile (603 km) long journey, but the time it takes to go to Siena from Palermo by bus can vary depending on specific dates or if traveling on weekends and holidays.
The first bus from Palermo to Siena leaves at 12: 05AM. Plan your trip with the Journey Planner   from Omio.
The last bus from Palermo to Siena leaves at 11: 39PM.
Yes, it is possible to travel from Palermo to Siena without having to change trains with FlixBus. There is 1 direct bus from Palermo to Siena each day. There may be fewer direct services available on weekends or holidays.
Take the Palermo to Siena bus with FlixBus or Itabus. However, it's always good to check out all possible bus providers for the journey to Siena from Palermo as there might be differences in the amenities they offer.
The cheapest month for a bus from Palermo to Siena is December.
It's helpful to compare your options as there are 4 ways to travel to Siena from Palermo including taking a train, bus, flight or ferry.
Yes, the following accessibility options are available when taking the bus from Palermo to Siena:
  • FlixBus
    • Assistance
    • Priority boarding
    • Wheelchair-accessible buses.
  • Itabus
    • Assistance
    • Dedicated seating areas
    • Accessible restrooms.
Yes, there are bathrooms on board the bus from Palermo to Siena for bus providers FlixBus and Itabus.
Some of the most interesting sights to explore in Siena are:
  • Piazza del Campo, a shell-shaped medieval square known for hosting the Palio horse race and surrounded by historic buildings
  • Siena Cathedral, a stunning example of Italian Romanesque-Gothic architecture featuring intricate marble work and art by famous masters
  • Palazzo Pubblico, a Gothic town hall with the Torre del Mangia offering panoramic views of the city
  • Basilica of San Domenico, a large church housing relics of Saint Catherine of Siena and notable frescoes
  • Santa Maria della Scala, a former hospital turned museum complex showcasing art and history exhibitions.
The best things to do in Siena include:
  • Torre del Mangia, a tall tower offering panoramic views of the city and surrounding countryside
  • Museo dell'Opera del Duomo, a museum housing an impressive collection of religious art and artifacts
  • Fortezza Medicea, a historic fortress offering beautiful views and a peaceful park for relaxation
  • Enoteca Italiana, a wine museum and tasting center where you can explore and enjoy Italian wines
  • Take a cooking class to learn how to make traditional Tuscan dishes.
Yes, bikes are allowed on board the bus with bus providers FlixBus and Itabus.
Whether you can cancel your bus ticket from Palermo to Siena depends on the bus companies:
  • FlixBus
    • You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
  • Itabus
    • You can cancel your ticket up to 24 hours before departure for a partial refund. Changes allowed for a fee.

To find the cheapest bus tickets for your trip from Palermo to Siena, follow these tips:

  • Book in advance: Tickets are often cheaper when booked early.
  • Be flexible with dates and times: Traveling during off-peak hours or on weekdays can help you save money.
  • Use our search filters: Sort results by price to quickly identify the most affordable options.
  • Look for special deals or discounts: Check for promotions or discounts available on our website and app.
  • Start your search now and compare ticket prices to find the best deal!

    Yes, there is food available to purchase on board the bus from Palermo to Siena.
    Yes, the following luggage options are included when booking a bus ticket from Palermo to Siena:
    • FlixBus
      • One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
    • Itabus
      • One carry-on bag up to 10kg and one checked bag up to 20kg.
    Yes, the following additional luggage options are available when booking a bus ticket from Palermo to Siena:
    • FlixBus
      • Additional luggage can be purchased for a fee.
    • Itabus
      • 5€ per additional bag.
    Yes, you can bring your pet on the bus from Palermo to Siena. The following conditions apply:
    • FlixBus
      • Small pets in carriers allowed
      • Guide dogs travel for free.
    • Itabus
      • Small pets allowed in carriers
      • Larger pets must be leashed and muzzled.
    You can reserve your seat on the bus from Palermo to Siena with the following bus providers: FlixBus and Itabus
    Yes, there are USB plugs on board the bus from Palermo to Siena with the following bus providers: FlixBus and Itabus.
    Yes, there is Wifi on board the bus from Palermo to Siena with the following bus providers: FlixBus and Itabus.

    popular bus stations

    Popular bus stations from Palermo to Siena

    Palermo
    Siena
    Siena, Stazione FS (Piazzale Carlo Rosselli)
    information
    Siena, P.za Gramsc
    information
    Siena, Siena/Viale Pietro Toselli
    information
    Siena, Via Fiorentina 135/Stellino
    information

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