4.9
4.6The cheapest and fastest buses from Palermo to Siena
Cheapest price
$62
Average price
$83
Fastest journey
16 h 20 m
Average duration
18 h 56 m
Buses per day
3
Distance
603 km
The best way to find a cheap bus ticket from Palermo to Siena is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Palermo to Siena will cost around $83 if you buy it on the day, but the cheapest tickets can be found for only $62.
Of the 3 buses that leave Palermo for Siena on Wed, May 13, 3 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Wed, May 13 the direct buses cover the 603 km distance in an average of 18 h 56 m but if you time it right, some buses will get you there in just 16 h 20 m .
On Wed, May 13 the slowest buses will take 20 h 45 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
1:25 PM16h20Palermo5:45 AMSiena$621One-way0 transfers- 7:10 PM19h44Palermo2:54 PMSiena$911One-way0 transfers
- 2:25 PM20h45Palermo11:10 AMSiena$971One-way0 transfers
- 1:25 PM16h20Palermo5:45 AMSiena$621One-way0 transfers
- 7:10 PM19h44Palermo2:54 PMSiena$911One-way0 transfers
- 2:25 PM20h45Palermo11:10 AMSiena$971One-way0 transfers
Travel Information
Compare train, bus, flight, and ferry for Palermo to Siena
Omio recommends booking the bus as it is the most popular option from Palermo to Siena among Omio's users. If you are prioritising price take the flight with prices starting from $23. For those with little time consider booking a flight which can get you there in 1h 23m. The ticket price range depends on the travel mode: a flight costs an average of $23, and a train costs an average of $93.
Distance: 374 miles (603 km)
Compare bus with
Most popular Bus | Flight | Train | Ferry | Driving |
|---|---|---|---|---|
$70 Average price | $40 Average price Cheapest | $155 Average price | $57 Average price | $92 Average price (fuel + tolls) |
17h 1m Average total duration 16h 31m Onboard + 30m Additional time* | 4h 23m Average total duration Fastest 1h 23m Onboard + 3h 0m Additional time* | 15h 2m Average total duration 14h 32m Onboard + 30m Additional time* | 20h 51m Average total duration 19h 51m Onboard + 1h 0m Additional time* | 12h 7m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Palermo to Siena:
A flight is $16 (€13) less than a ferry for this route with tickets for a ferry from Palermo to Siena costing on average $57 (€45).
A flight is $29 (€24) less than a bus for this route with tickets for a bus from Palermo to Siena costing on average $70 (€56).
A flight is $115 (€92) less than a train for this route with tickets for a train from Palermo to Siena costing on average $155 (€124).
Other travel options to Siena take longer:
Train takes on average 14h 32m.
Bus takes on average 16h 31m.
Ferry takes on average 19h 51m.
Tickets start at around $70 (€56) compared to roughly $92 (€74) in fuel and tolls — a saving of about $22 (€18). The journey takes 16h 31m versus 12h 7m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by FlixBus.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
Live departures
Palermo to Siena bus times
The table below shows live departures for Palermo to Siena buses for tomorrow, Wednesday, May 13. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| 1:25 PM Palermo | 16h20 | 5:45 AM Siena | 0 transfersDirect | |
| 2:25 PM Palermo | 20h45 | 11:10 AM Siena | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Palermo to Siena by train, bus, flight, or ferry
Compare train, bus, flight, and ferry prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
May 13
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May 17
May 18
May 19
Why should you book Palermo to Siena buses with Omio?
Why book with Omio vs FlixBus?
- Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of Itabus to find the best option for your trip from Palermo to Siena.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train, bus, flight and ferry to ensure you get the best deal for traveling from Palermo to Siena.
Why book with Omio over Wanderu, Trainline or Checkmybus?
- Compare with other providers: On Omio, you can also compare tickets for the likes of Itabus to find the best option for your trip from Palermo to Siena.
- Multiple modes of transport: Omio allows you to compare travel options including train, bus, flight and ferry to find the ideal travel option from Palermo to Siena.
Journey information
Overview: Bus from Palermo to Siena
ItalyItaly
Buses from Palermo to Siena run on average 4 times per day, taking around 16h 31m. Cheap bus tickets for this journey start at $33 (€26) but you can travel from only $23 (€19) by flight.
There are 1 buses per day. The earliest bus runs at 05:00, the last at 22:25. The fastest bus covers the 374 miles (603 km) distance in 16h 20m.
Distance 374 miles (603 km) |
Average bus duration 16h 31m |
Cheapest ticket price $33 (€26) |
Buses per day 4 |
Direct buses 1 |
Fastest bus 16h 20m |
First bus 5:00 AM |
Last bus 10:25 PM |
Cheapest Month May |
Cheapest Day Fri |
High Season Jul - Sep |
Low Season Oct - Dec |
Busiest Day Mon |
Least Busy Day Wed |
Best time to book 14 days |
Bus providers: FlixBus, Itabus from Palermo to SienaYou can travel by bus between Palermo to Siena with FlixBus, Itabus for as low as $23 (€19). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Itabus
FAQs: Bus from Palermo to Siena
Find answers to the most common questions about traveling from Palermo to Siena by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Siena, this guide helps you travel smarter and with confidence.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Itabus
- Assistance
- Dedicated seating areas
- Accessible restrooms.
- Piazza del Campo, a shell-shaped medieval square known for hosting the Palio horse race and surrounded by historic buildings
- Siena Cathedral, a stunning example of Italian Romanesque-Gothic architecture featuring intricate marble work and art by famous masters
- Palazzo Pubblico, a Gothic town hall with the Torre del Mangia offering panoramic views of the city
- Basilica of San Domenico, a large church housing relics of Saint Catherine of Siena and notable frescoes
- Santa Maria della Scala, a former hospital turned museum complex showcasing art and history exhibitions.
- Torre del Mangia, a tall tower offering panoramic views of the city and surrounding countryside
- Museo dell'Opera del Duomo, a museum housing an impressive collection of religious art and artifacts
- Fortezza Medicea, a historic fortress offering beautiful views and a peaceful park for relaxation
- Enoteca Italiana, a wine museum and tasting center where you can explore and enjoy Italian wines
- Take a cooking class to learn how to make traditional Tuscan dishes.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Itabus
- You can cancel your ticket up to 24 hours before departure for a partial refund. Changes allowed for a fee.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Itabus
- One carry-on bag up to 10kg and one checked bag up to 20kg.
- FlixBus
- Additional luggage can be purchased for a fee.
- Itabus
- 5€ per additional bag.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
- Itabus
- Small pets allowed in carriers
- larger pets must be leashed and muzzled.
popular bus stations
Popular bus stations from Palermo to Siena
Most popular bus connections from Palermo
More options for your journey from Palermo to Siena
Here are some other resources that might have the information you need
Most popular buses to and from Siena and Palermo
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