- Must visit
Museo Civico
Siena’s main civic museum displays Lorenzetti’s frescoes and superb medieval art inside the historic town hall. It is essential for understanding the city.
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The cheapest and fastest buses from Palermo to Siena
Showing times, prices and bookable tickets for Sep 26
Cheapest price on Sep 26
$38
Average ticket price on Sep 26
$77
Fastest journey on Sep 26
16 h 20 m
Average journey duration on Sep 26
17 h 39 m
Buses on Sep 26
4
Distance
603 km
Cheap tickets
The best way to find a cheap bus ticket from Palermo to Siena is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Palermo to Siena will cost around $77 if you buy it on the day, but the cheapest tickets can be found for only $38.
Fast buses
On Sat, Sep 26, we found 4 buses from Palermo to Siena, including 4 direct services.
On Sat, Sep 26 the direct buses cover the 603 km distance in an average of 17 h 39 m but if you time it right, some buses will get you there in just 16 h 20 m .
On Sat, Sep 26 the slowest buses will take 21 h 25 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
2:15 PM16h30Palermo6:45 AMSiena$381One-way0 transfers- 2:25 PM16h20Palermo6:45 AMSiena$471One-way0 transfers
- 1:25 PM16h20Palermo5:45 AMSiena$831One-way0 transfers
- 7:10 PM21h25Palermo4:35 PMSiena$1391One-way0 transfers
- 2:25 PM16h20Palermo6:45 AMSiena$471One-way0 transfers
- 1:25 PM16h20Palermo5:45 AMSiena$831One-way0 transfers
- 2:15 PM16h30Palermo6:45 AMSiena$381One-way0 transfers
- 7:10 PM21h25Palermo4:35 PMSiena$1391One-way0 transfers
Palermo to Siena Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 01:25PM | Arrival Time 05:45AM | Duration 16h20 | Departure days Mon, Tue, Wed, Sat, Sun | Cheapest price $52 |
Operator FlixBus | Departure Time 02:15PM | Arrival Time 06:45AM | Duration 16h30 | Departure days Sat | Cheapest price $38 |
Operator FlixBus | Departure Time 02:25PM | Arrival Time 06:45AM | Duration 16h20 | Departure days Mon, Tue, Wed, Sat, Sun | Cheapest price $47 |
Operator FlixBus | Departure Time 03:10PM | Arrival Time 09:25AM | Duration 18h15 | Departure days Sun | Cheapest price $59 |
Operator FlixBus | Departure Time 03:25PM | Arrival Time 07:45AM | Duration 16h20 | Departure days Thu, Fri | Cheapest price $68 |
Operator FlixBus | Departure Time 04:10PM | Arrival Time 11:20AM | Duration 19h10 | Departure days Mon, Sun | Cheapest price $34 |
Operator FlixBus | Departure Time 07:10PM | Arrival Time 02:54PM | Duration 19h44 | Departure days Wed, Sat | Cheapest price $88 |
Operator FlixBus | Departure Time 09:10PM | Arrival Time 04:54PM | Duration 19h44 | Departure days Thu, Fri | Cheapest price $94 |
Live departures
Palermo to Siena bus times
The table below shows live departures for Palermo to Siena buses for today, Friday, September 25. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| FlixBus · FlixBus | 9:10 PM Palermo, Via Tommaso Fazello (Terminal Bus) | 19h44 | 4:54 PM Siena, Siena/Viale Pietro Toselli | 1 transfer | |
| FlixBus · FlixBus | 9:10 PM Palermo, Via Tommaso Fazello (Terminal Bus) | 20h00 | 5:10 PM Siena, P.za Gramsc | 1 transfer | |
| FlixBus · FlixBus | 9:10 PM Palermo, Via Tommaso Fazello (Terminal Bus) | 19h50 | 5:00 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 1 transfer | |
| Saturday, September 26 | |||||
| 1:25 PM Palermo | 16h20 | 5:45 AM Siena | 0 transfersDirect | |
| 2:15 PM Palermo | 16h30 | 6:45 AM Siena | 0 transfersDirect | |
| 2:25 PM Palermo | 16h20 | 6:45 AM Siena | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Palermo to Siena by train, bus, flight, or ferry
Compare train, bus, flight, and ferry prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Palermo to Siena buses with Omio?
FlixBus as well as Itabus offer buses services from Palermo to Siena.
Omio is an official ticket reseller for all your travel options from Palermo to Siena.
Why book with Omio vs FlixBus?
- Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of Itabus to find the best option for your trip from Palermo to Siena.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train, bus, flight and ferry to ensure you get the best deal for traveling from Palermo to Siena.
Why book with Omio over Wanderu, Trainline or Checkmybus?
- Compare with other providers: On Omio, you can also compare tickets for the likes of Itabus to find the best option for your trip from Palermo to Siena.
- Multiple modes of transport: Omio allows you to compare travel options including train, bus, flight and ferry to find the ideal travel option from Palermo to Siena.
Journey information
Overview: Bus from Palermo to Siena
ItalyItaly
Buses from Palermo to Siena run on average 6 times per day, taking around 16h 53m. Cheap bus tickets for this journey start at $45 (€37) but you can travel from only $12 (€10) by train.
There are 1 buses per day. The earliest bus runs at 05:00, the last at 22:25. The fastest bus covers the 374 miles (603 km) distance in 16h 20m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Train from $12 (€10)
Distance 374 miles (603 km) |
Average bus duration 16h 53m |
Cheapest ticket price $45 (€37) |
Buses per day 6 |
Direct buses 1 |
Fastest bus 16h 20m |
First bus 5:00 AM |
Last bus 10:25 PM |
Cheapest Month May |
Cheapest Day Sun |
High Season Jul - Sep |
Low Season Apr - Jun |
Busiest Day Tue |
Least Busy Day Wed |
Best time to book 56 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Train from $12 (€10)
Bus providers: FlixBus, Itabus from Palermo to SienaYou can travel by bus between Palermo to Siena with FlixBus, Itabus for as low as $12 (€10). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average FlixBus Duration
16h 20m
Cheapest FlixBus Price
$54 (€44)
FlixBus frequency
6 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Itabus
About
Itabus is a leading bus company in Italy, providing reliable and comfortable transportation services to its customers. Itabus operates a fleet of modern buses, ranging from luxury coaches to standard buses, all equipped with air conditioning, comfortable seating, and onboard entertainment.
Luggage & cancellation policy
Average Itabus Duration
16h 30m
Cheapest Itabus Price
$45 (€37)
Itabus frequency
1 a day
Luggage included
One carry-on bag up to 10kg and one checked bag up to 20kg.
Additional luggage
5€ per additional bag.
Cancellation Policy
You can cancel your ticket up to 24 hours before departure for a partial refund. Changes allowed for a fee.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Dedicated seating areas; Accessible restrooms.
Bikes
Bikes are allowed.
Pets
Small pets allowed in carriers; larger pets must be leashed and muzzled.
Complete guide to Siena
Things to do in Siena
Discover the best of Siena — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Siena trip today.
- Must visit
Santa Maria della Scala
This major museum complex occupies a former hospital and combines archaeology, frescoes, chapels, and underground spaces in a memorable setting.
- Must visit
Museo dell'Opera del Duomo
The cathedral museum preserves sculptures, stained glass, and treasures from the Duomo complex, including close views of masterpieces and architecture.
- Must visit
Piazza del Campo
Siena’s iconic shell-shaped square is the social and visual heart of the city, perfect for architecture, people-watching, and understanding the Palio.
- Must visit
Piazza del Duomo
This broad square in front of the cathedral frames some of Siena’s finest Gothic monuments and is a natural stop on any walking route.
- Recommended
Via di Città
The city’s main pedestrian street links major sights with shops and noble facades. It is ideal for a first walk through Siena’s historic core.
- Vegetarian
- Vegan
Ribollita
Thick rustic soup of bread, beans, cavolo nero and vegetables. A Tuscan staple in Siena, prized for peasant roots and deep, comforting flavor.
- Vegetarian
Acquacotta
Dense vegetable and bread soup made with beans, tomato, onion, celery and stale bread. Traditional cucina povera, often linked to Sienese home cooking.
Pici
Hand-rolled thick spaghetti, usually served with rich garlic-forward tomato sauce or duck ragù. A classic Tuscan pasta common in Siena trattorie.
La Taverna Di San Giuseppe
Popular central trattoria focused on pici, ribollita and other regional staples, offering a casual atmosphere near major sights.
Osteria Le Logge
Well-known osteria for classic Tuscan and Sienese dishes, with a cozy brick interior and strong local wine selection.
Ristorante Tar-Tufo
Elegant Michelin-starred restaurant near Piazza del Campo, known for refined Tuscan tasting menus and polished historic atmosphere.
Euro (€)
Moderate for Italy: lodging and dining cost more than small towns, but transit is limited and many sights are walkable.
Average meal costs
- Budget
- €8-15 for pizza slices, panini, or casual lunch.
- Mid-range
- €20-35 per person for a restaurant meal.
- Fine dining
- €60+ per person for upscale dining.
- Coffee
- €1.30-3 for espresso or cappuccino.
Tipping culture
Service is often included or covered by coperto. Round up or leave 5-10% for great restaurant service; taxis are usually rounded up; cafés need no tip.
AT Bus
Get the appOfficial public transport app
Prices
- Single ticket
- €1.50
- Day pass
- €5.50
To the city center
Siena, Stazione FS (Piazzale Carlo Rosselli) -> Piazza del Campo, Siena
- Distance
- 1.8 km
- Travel time
- 6 min
- Urban buses in Siena are run by AT Bus. Buy tickets in advance in the app, at vending points, or authorized retailers.
- Contactless bank card payment availability onboard is not reliably published for all Siena urban buses. Use the AT Bus app or a paper ticket to avoid issues.
FAQs: Bus from Palermo to Siena
Find answers to the most common questions about traveling from Palermo to Siena by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Siena, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Palermo to Siena can start from as little as $45 (€37) when you book in advance. The average bus ticket price for Palermo to Siena is $121 (€99) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Palermo to Siena is 16h 20m to travel the 374 miles (603 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Palermo to Siena leaves at 5:00 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Palermo to Siena leaves at 10:25 PM.
Yes, there are 1 direct buses a day from Palermo to Siena with FlixBus. Schedules can vary on holidays or weekends with fewer direct buses.
When taking a bus from Palermo to Siena, you can count on FlixBus, Itabus for the best way to get you to Siena. You can also check all possible bus companies who offer a service between Palermo and Siena and compare the amenities they offer before buying a bus ticket.
When departing from Palermo , you have various bus station options to start your journey from including Palermo, Via Tommaso Fazello (Terminal Bus) . When arriving in Siena , you can end your journey in bus stations like Siena, Stazione FS (Piazzale Carlo Rosselli), Siena, Siena/Viale Pietro Toselli, Siena, P.za Gramsc .Passengers board the bus most frequently from Palermo, Via Tommaso Fazello (Terminal Bus), which is located around 0 miles (1 km) away from the city centre, and they get off the bus at Siena, Stazione FS (Piazzale Carlo Rosselli), located 1 away from the city centre.
It's helpful to compare your options as there are 4 ways to travel between Palermo and Siena including taking a train, bus, flight, and ferry.
Yes, the following accessibility options are available when taking the bus from Palermo to Siena:
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Itabus
- Assistance
- Dedicated seating areas
- Accessible restrooms.
Yes, there are bathrooms on board the bus from Palermo to Siena for bus company FlixBus, Itabus.
Whether you can cancel your bus ticket from Palermo to Siena depends on the bus companies:
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Itabus
- You can cancel your ticket up to 24 hours before departure for a partial refund. Changes allowed for a fee.
Yes, bikes are allowed on board the bus with bus company FlixBus, Itabus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Palermo to Siena.
Yes, the following luggage options are included when booking a bus ticket from Palermo to Siena:
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Itabus
- One carry-on bag up to 10kg and one checked bag up to 20kg.
Yes, the following additional luggage options are available when booking a bus ticket from Palermo to Siena:
- FlixBus
- Additional luggage can be purchased for a fee.
- Itabus
- 5€ per additional bag.
Yes, you can bring your pet on the bus from Palermo to Siena. The following conditions apply:
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
- Itabus
- Small pets allowed in carriers
- larger pets must be leashed and muzzled.
You can reserve your seat on the bus from Palermo to Siena with the following bus company: FlixBus, Itabus
Yes, there are USB plugs on board the bus from Palermo to Siena with the following bus company: FlixBus, Itabus.
Yes, there is Wifi on board the bus from Palermo to Siena with the following bus company: FlixBus, Itabus.
Italy uses the euro (EUR) as its currency. Travelers generally find it convenient to use cards for most payments, especially in cities and larger establishments, but carrying some cash is advisable for small shops, markets, and rural areas where card acceptance may be limited.
In Siena, travelers should be cautious of pickpocketing, especially in crowded areas like Piazza del Campo and on public transportation. Common scams include overpriced taxi rides and unofficial ticket sellers near popular attractions. Staying aware of surroundings and using authorized services helps ensure a safe visit.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Palermo to Siena
Most Palermo to Siena buses use the Palermo, Via Tommaso Fazello (Terminal Bus) to Siena, Stazione FS (Piazzale Carlo Rosselli) station pair, with some services arriving at Siena, Siena/Viale Pietro Toselli. Use this guide to compare Palermo and Siena bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in Palermo
Arrival bus stations in Siena
Which Siena station do buses from Palermo arrive at?
Buses from Palermo to Siena most often arrive at Siena, Stazione FS (Piazzale Carlo Rosselli). Some services arrive at Siena, Siena/Viale Pietro Toselli, so check your ticket before travel to confirm your Siena arrival station.
Siena, Stazione FS (Piazzale Carlo Rosselli)Siena - Ferrovia, 53100 Siena SI, Italy
City-centre transport
Getting to Siena, Stazione FS (Piazzale Carlo Rosselli) from Siena city centre
Siena, Stazione FS (Piazzale Carlo Rosselli) is 1 km from Siena city centre. Public transport options include:
BusS10, 0S3, 544 · 7m · $1 · every ~6 min
Siena, Stazione FS (Piazzale Carlo Rosselli) bus station facilities and services
Siena, Stazione FS (Piazzale Carlo Rosselli) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Cafeteria and vending machines available.
Wi-Fi and ATMs
Wi-Fi is available at Siena, Stazione FS (Piazzale Carlo Rosselli). ATMs are available at Siena, Stazione FS (Piazzale Carlo Rosselli).
Tickets and information
Ticket office support is available at Siena, Stazione FS (Piazzale Carlo Rosselli).
Parking, taxis and toilets
Available at Siena, Stazione FS (Piazzale Carlo Rosselli): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Siena, Stazione FS (Piazzale Carlo Rosselli): Wheelchair ramps are provided.
Siena, Siena/Viale Pietro ToselliViale Pietro Toselli, 53100 Siena SI, Italy
City-centre transport
Getting to Siena, Siena/Viale Pietro Toselli from Siena city centre
Siena, Siena/Viale Pietro Toselli is 1 km from Siena city centre. Public transport options include:
BusS52 · 14m · $1 · every ~5 min
Siena, Siena/Viale Pietro Toselli bus station facilities and services
Siena, Siena/Viale Pietro Toselli has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Nearby cafes and fast food available.
Wi-Fi and ATMs
Wi-Fi is available at Siena, Siena/Viale Pietro Toselli. ATMs are available at Siena, Siena/Viale Pietro Toselli.
Tickets and information
Ticket office support is available at Siena, Siena/Viale Pietro Toselli.
Parking, taxis and toilets
Available at Siena, Siena/Viale Pietro Toselli: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Siena, Siena/Viale Pietro Toselli: Ramps and accessible paths available.
Siena, P.za GramscPiazza Gramsci (Arrivo), 53100 Siena SI, Italy
City-centre transport
Getting to Siena, P.za Gramsc from Siena city centre
TRUE
Siena, P.za Gramsc bus station facilities and services
Siena, P.za Gramsc has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Siena, P.za Gramsc. ATMs are available at Siena, P.za Gramsc.
Tickets and information
Ticket office support is available at Siena, P.za Gramsc.
Parking, taxis and toilets
Available at Siena, P.za Gramsc: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Siena, P.za Gramsc: The station is accessible with ramps and lowered curbs.
More options for your journey from Palermo to Siena
Here are some other resources that might have the information you need
Most popular buses to and from Siena and Palermo
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