The cheapest and fastest buses from Catania to Siena
Cheapest price
$40
Average price
$44
Fastest journey
13 h 10 m
Average duration
14 h 10 m
Buses per day
2
Distance
721 km
The best way to find a cheap bus ticket from Catania to Siena is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Catania to Siena will cost around $44 if you buy it on the day, but the cheapest tickets can be found for only $40.
Of the 2 buses that leave Catania for Siena on Sat, Mar 14, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sat, Mar 14 the direct buses cover the 721 km distance in an average of 14 h 10 m but if you time it right, some buses will get you there in just 13 h 10 m .
On Sat, Mar 14 the slowest buses will take 15 h 10 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.




Travel Information
Compare bus, train, and flight for Catania to Siena
Omio recommends booking the bus as it is the most popular option from Catania to Siena among Omio's users. If you are prioritising price take the bus with prices starting from $35. For those with little time consider booking a flight which can get you there in 1h 38m. The ticket price range depends on the travel mode: a bus costs an average of $35, and a flight costs an average of $22.
Distance: 448 miles (721 km)
Compare bus with
Most popular Bus | Flight | Train |
|---|---|---|
$56 Average price Cheapest | $125 Average price | $118 Average price |
15h 14m Average total duration 14h 44m Onboard + 30m Additional time* | 4h 38m Average total duration Fastest 1h 38m Onboard + 3h 0m Additional time* | 13h 23m Average total duration 12h 53m Onboard + 30m Additional time* |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company |
Direct Options | Direct Options | Direct Options |
Catania to Siena Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 09:25AM | Arrival Time 12:40AM | Duration 15h15 | Departure days Fri | Cheapest price $72 |
Operator FlixBus | Departure Time 06:40PM | Arrival Time 07:45AM | Duration 13h05 | Departure days Fri | Cheapest price $37 |
Operator Itabus | Departure Time 07:55PM | Arrival Time 10:50AM | Duration 14h55 | Departure days Fri | Cheapest price $49 |
Operator FlixBus | Departure Time 08:05PM | Arrival Time 11:25AM | Duration 15h20 | Departure days Fri | Cheapest price $72 |
Operator Itabus | Departure Time 08:15PM | Arrival Time 10:50AM | Duration 14h35 | Departure days Fri | Cheapest price $54 |
Operator FlixBus | Departure Time 09:30PM | Arrival Time 02:50PM | Duration 17h20 | Departure days Fri | Cheapest price $71 |
Operator Itabus | Departure Time 09:50PM | Arrival Time 06:30PM | Duration 20h40 | Departure days Fri | Cheapest price $40 |
Operator Itabus | Departure Time 10:10PM | Arrival Time 06:30PM | Duration 20h20 | Departure days Fri | Cheapest price $40 |
Live departures
Catania to Siena bus times
The table below shows live departures for Catania to Siena buses for today, Friday, March 13. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 8:30 PM Catania, Via D'Amico | 14h40 | 11:10 AM Siena, Stazione FS (Piazzale Carlo Rosselli) | 1 transfer | |
FlixBus · FlixBus | 8:30 PM Catania, Via D'Amico | 17h20 | 1:50 PM Siena, Siena/Viale Pietro Toselli | 1 transfer | |
4412 · 2490 | 8:50 PM Catania, Aeroporto di Catania-Fontanarossa (P2 Breve Sosta) | 20h40 | 5:30 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 1 transfer | |
4412 · 2490 | 9:10 PM Catania, Via D'Amico | 20h20 | 5:30 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 1 transfer | |
| Saturday, March 14 | |||||
![]() | 5:35 PM Catania | 13h10 | 6:45 AM Siena | 0 transfersDirect | |
![]() | 7:05 PM Catania | 15h10 | 10:15 AM Siena | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Catania to Siena by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Mar 14
Mar 15
Mar 16
Mar 17
Mar 18
Mar 19
Mar 20
Why should you book Catania to Siena buses with Omio?
Why book with Omio vs FlixBus?
- Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of Itabus to find the best option for your trip from Catania to Siena.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Catania to Siena.
Why book with Omio over Wanderu, Trainline or Checkmybus?
- Compare with other providers: On Omio, you can also compare tickets for the likes of Itabus to find the best option for your trip from Catania to Siena.
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Catania to Siena.
Journey information
Overview: Bus from Catania to Siena
Buses from Catania to Siena run on average 7 times per day, taking around 14h 44m. Cheap bus tickets for this journey start at $35 (€28) but you can travel from only $22 (€18) by flight.
There are 3 buses per day. The earliest bus runs at 04:00, the last at 23:45. The fastest bus covers the 448 miles (721 km) distance in 13h 5m.
Distance 448 miles (721 km) |
Average bus duration 14h 44m |
Cheapest ticket price $35 (€28) |
Buses per day 7 |
Direct buses 3 |
Fastest bus 13h 5m |
First bus 04:00 |
Last bus 23:45 |
Bus providers: FlixBus, Itabus from Catania to SienaYou can travel by bus between Catania to Siena with FlixBus, Itabus for as low as $22 (€18). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Itabus
FAQs: Bus from Catania to Siena
Find answers to the most common questions about traveling from Catania to Siena by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Siena, this guide helps you travel smarter and with confidence.

- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Itabus
- Assistance
- Dedicated seating areas
- Accessible restrooms.
- Piazza del Campo, a shell-shaped medieval square known for hosting the Palio horse race and surrounded by historic buildings
- Siena Cathedral, a stunning example of Italian Romanesque-Gothic architecture featuring intricate marble work and art by famous masters
- Palazzo Pubblico, a Gothic town hall with the Torre del Mangia offering panoramic views of the city
- Basilica of San Domenico, a large church housing relics of Saint Catherine of Siena and notable frescoes
- Santa Maria della Scala, a former hospital turned museum complex showcasing art and history exhibitions.
- Torre del Mangia, a tall tower offering panoramic views of the city and surrounding countryside
- Museo dell'Opera del Duomo, a museum housing an impressive collection of religious art and artifacts
- Fortezza Medicea, a historic fortress offering beautiful views and a peaceful park for relaxation
- Enoteca Italiana, a wine museum and tasting center where you can explore and enjoy Italian wines
- Take a cooking class to learn how to make traditional Tuscan dishes.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Itabus
- You can cancel your ticket up to 24 hours before departure for a partial refund. Changes allowed for a fee.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Itabus
- One carry-on bag up to 10kg and one checked bag up to 20kg.
- FlixBus
- Additional luggage can be purchased for a fee.
- Itabus
- 5€ per additional bag.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
- Itabus
- Small pets allowed in carriers
- larger pets must be leashed and muzzled.
popular bus stations
Popular bus stations from Catania to Siena
Most popular bus connections from Catania
More options for your journey from Catania to Siena
Here are some other resources that might have the information you need



