- Must visit
Santa Maria della Scala
A vast former hospital complex opposite the cathedral, now a museum center with archaeological finds, frescoed halls, and temporary exhibitions. One of Siena’s richest cultural sites.
Cheapest price
$50
Average price
$51
Fastest journey
13 h 5 m
Average duration
14 h
Buses per day
2
Distance
721 km
The best way to find a cheap bus ticket from Catania to Siena is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Catania to Siena will cost around $51 if you buy it on the day, but the cheapest tickets can be found for only $50.
Of the 2 buses that leave Catania for Siena on Sat, Jun 13, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sat, Jun 13 the direct buses cover the 721 km distance in an average of 14 h but if you time it right, some buses will get you there in just 13 h 5 m .
On Sat, Jun 13 the slowest buses will take 14 h 55 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.




Omio recommends booking the bus as it is the most popular option from Catania to Siena among Omio's users. If you are prioritising price take the flight with prices starting from $33. For those with little time consider booking a flight which can get you there in 1h 38m. The ticket price range depends on the travel mode: a flight costs an average of $33, and a train costs an average of $85.
Distance: 448 miles (721 km)
Most popular Bus | Flight | Train | Driving |
|---|---|---|---|
$51 Average price | $46 Average price Cheapest | $130 Average price | $65 Average price (fuel + tolls) |
15h 19m Average total duration 14h 49m Onboard + 30m Additional time* | 4h 38m Average total duration Fastest 1h 38m Onboard + 3h 0m Additional time* | 13h 23m Average total duration 12h 53m Onboard + 30m Additional time* | 10h 40m Average total duration (door-to-door) |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Catania to Siena:
A flight is $6 (€4) less than a bus for this route with tickets for a bus from Catania to Siena costing on average $51 (€42).
A flight is $84 (€68) less than a train for this route with tickets for a train from Catania to Siena costing on average $130 (€105).
Other travel options to Siena take longer:
Train takes on average 12h 53m.
Bus takes on average 14h 49m.
Tickets start at around $51 (€42) compared to roughly $65 (€53) in fuel and tolls — a saving of about $13 (€11). The journey takes 14h 49m versus 10h 40m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by FlixBus, Itabus.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 09:25AM | Arrival Time 12:40AM | Duration 15h15 | Departure days Tue, Thu | Cheapest price $73 |
Operator FlixBus | Departure Time 04:40PM | Arrival Time 05:45AM | Duration 13h05 | Departure days Mon, Sat, Sun | Cheapest price $52 |
Operator FlixBus | Departure Time 05:40PM | Arrival Time 06:45AM | Duration 13h05 | Departure days Mon, Wed, Fri | Cheapest price $40 |
Operator Itabus | Departure Time 05:55PM | Arrival Time 08:50AM | Duration 14h55 | Departure days Sun | Cheapest price $89 |
Operator FlixBus | Departure Time 06:40PM | Arrival Time 07:45AM | Duration 13h05 | Departure days Tue, Thu | Cheapest price $52 |
Operator Itabus | Departure Time 06:55PM | Arrival Time 09:50AM | Duration 14h55 | Departure days Mon, Wed, Fri, Sat, Sun | Cheapest price $49 |
Operator Itabus | Departure Time 07:55PM | Arrival Time 10:50AM | Duration 14h55 | Departure days Tue, Thu | Cheapest price $78 |
Operator FlixBus | Departure Time 08:10PM | Arrival Time 02:50PM | Duration 18h40 | Departure days Tue, Thu | Cheapest price $73 |
Operator Itabus | Departure Time 08:15PM | Arrival Time 10:50AM | Duration 14h35 | Departure days Tue, Thu | Cheapest price $78 |
Operator Itabus | Departure Time 08:50PM | Arrival Time 05:30PM | Duration 20h40 | Departure days Fri | Cheapest price $49 |
Operator FlixBus | Departure Time 11:55PM | Arrival Time 05:00PM | Duration 17h05 | Departure days Tue, Thu | Cheapest price $79 |
The table below shows live departures for Catania to Siena buses for today, Friday, June 12. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 5:40 PM Catania | 13h05 | 6:45 AM Siena | 0 transfersDirect | |
![]() | 6:55 PM Catania | 14h55 | 9:50 AM Siena | 0 transfersDirect | |
![]() | 8:50 PM Catania | 20h40 | 5:30 PM Siena | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Catania to Siena run on average 7 times per day, taking around 14h 49m. Cheap bus tickets for this journey start at $35 (€28) but you can travel from only $33 (€27) by flight.
There are 3 buses per day. The earliest bus runs at 04:00, the last at 23:55. The fastest bus covers the 448 miles (721 km) distance in 13h 5m.
Distance 448 miles (721 km) |
Average bus duration 14h 49m |
Cheapest ticket price $35 (€28) |
Buses per day 7 |
Direct buses 3 |
Fastest bus 13h 5m |
First bus 4:00 AM |
Last bus 11:55 PM |
Cheapest Month Jul |
Cheapest Day Tue |
High Season Jul - Sep |
Low Season Oct - Dec |
Busiest Day Sat |
Least Busy Day Sat |
Best time to book 14 days |
Discover the best of Siena — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Siena trip today.
A vast former hospital complex opposite the cathedral, now a museum center with archaeological finds, frescoed halls, and temporary exhibitions. One of Siena’s richest cultural sites.
Siena’s civic museum inside Palazzo Pubblico, famous for Ambrogio Lorenzetti’s fresco cycle Allegory of Good and Bad Government and rooms tied to the city’s republican history.
The cathedral museum complex includes works linked to the Duomo, including sculpture, stained glass, and access to important cathedral-related spaces.
Siena’s shell-shaped central square is one of Italy’s most famous urban spaces, home to the Palio and essential for understanding the city’s civic identity.
A famous panoramic terrace in the unfinished cathedral extension, popular for skyline photos and increasingly prominent on social media.
This elevated panorama over Siena’s rooftops and countryside is especially sought out for sunset photos and dramatic views over the cathedral area.
Thick hand-rolled pasta from southern Tuscany, usually served with a garlicky tomato sauce made with aglione, a local mild garlic. It is one of the most emblematic pasta dishes around Siena.
A traditional Tuscan bread and vegetable soup, typically made with beans, cavolo nero, and stale bread, then reheated to deepen the flavor. It is a classic rustic dish eaten across Siena.
A thick tomato and bread soup with olive oil, garlic, and basil. It is a simple but beloved Tuscan staple that showcases the region's bread-based cucina povera tradition.
Well-known traditional restaurant in a historic setting, celebrated for Tuscan classics, pasta, and meat dishes, with a warm and refined atmosphere.
Established upscale dining room near the center, known for elegant Tuscan cuisine, seasonal ingredients, and polished service in a classic Sienese setting.
Long-running central restaurant appreciated for honest Tuscan cooking, generous portions, and a simple local feel. A solid choice for classic Sienese fare.
Moderate by Italian standards. Historic-center dining costs more, but cafes, bakeries, and simple trattorias can be good value.
Service is often included or covered by coperto. Tipping is not required, but rounding up or leaving 5-10% for very good restaurant service is appreciated. Small change for taxis is enough.
Official public transport app
Siena, Stazione FS (Piazzale Carlo Rosselli) -> Piazza del Campo, Siena
Find answers to the most common questions about traveling from Catania to Siena by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Siena, this guide helps you travel smarter and with confidence.

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