Travel Information
Compare train, bus, and flight for Syracuse, NY to Chicago, IL
Omio recommends booking the train as it is the most popular option from Syracuse, NY to Chicago, IL among Omio's users. If you are prioritising price take the train with prices starting from $56. For those with little time consider booking a flight which can get you there in 2h 23m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.3 - 0.9kg. The ticket price range depends on the travel mode: a train costs an average of $56, and a flight costs an average of $85.
Distance: 591 miles (952 km)
Compare train with
Most popular Train | Bus | Flight |
|---|---|---|
$165 Average price Cheapest | $174 Average price | $300 Average price |
13h 37m Average total duration 13h 7m Onboard + 30m Additional time* | 16h 0m Average total duration 15h 30m Onboard + 30m Additional time* | 5h 23m Average total duration Fastest 2h 23m Onboard + 3h 0m Additional time* |
0.3 - 0.9kg CO2 emissions Lowest | 1.0 - 2.4kg CO2 emissions | 2.9 - 5.7kg CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Travel optionsfrom Syracuse, NY to Chicago, IL
How to get from Syracuse, NY to Chicago, IL by train, bus or flight.
Our recommendation
The best way to travel from Syracuse, NY to Chicago, IL is by taking a train because it’s the best combination of price and speed.
49 Lake Shore LimitedCheapest
49 Lake Shore LimitedFastest
AA3398Other options
449 Lake Shore Limited
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B6315 · B61205
B6374 · B6311Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
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FAQs: Travel from Syracuse, NY to Chicago, IL
Travel to Chicago, IL easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Syracuse, NY to Chicago, IL.

This is compared to other travel options from Syracuse, NY to Chicago, IL:
A train is $29 (€24) less than a flight for this route with tickets for a flight from Syracuse, NY to Chicago, IL costing on average $85 (€70).
A train is $35 (€29) less than a bus for this route with tickets for a bus from Syracuse, NY to Chicago, IL costing on average $91 (€74).
Other travel options to Chicago, IL take longer:
Train takes on average 13h 7m.
Bus takes on average 16h 35m.
- Around 36 flights per day.
- Around 4 buses per day.
- Around 2 trains per day.
However, we recommend checking specific travel dates for your route between Syracuse, NY and Chicago, IL as scheduled services by train, bus, and flight can vary by season or day of the week.
- Buses mostly depart from Syracuse, Walsh Cir (Syracuse Bus Station), NY and arrive in Chicago, Greyhound Bus Station.
- Trains mostly depart from Syracuse Station, Syracuse, NY and arrive in Chicago Union Station, Chicago, IL.
- Flights mostly depart from Syracuse Hancock International Airport and arrive in O'Hare International Airport.
- Travel with Greyhound to go to Chicago, IL by bus.
- Travel with United to go to Chicago, IL by flight.
- Travel with Amtrak to go to Chicago, IL by train.
- 3 direct flights per day with United.
- 2 direct trains per day with Amtrak.
Travelling from Syracuse, NY to Chicago, IL: related information
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