Travel Information
Compare train, bus, and flight for Syracuse, NY to Chicago, IL
Omio recommends booking the train as it is the most popular option from Syracuse, NY to Chicago, IL among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $106 For those with little time, consider booking a flight, which has an average total journey time of 4h 23m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.3 - 0.9kg. Average ticket prices depend on the travel mode: a bus costs an average of $106, while a flight costs an average of $237.
Distance: 591 miles (952 km)
Compare train with
Most popular Train | Bus | Flight | Driving |
|---|---|---|---|
$155 Average price | $106 Average price Cheapest | $237 Average price | $201 Average price (fuel + tolls) |
13h 36m Average total duration 13h 6m Onboard + 30m Additional time* | 16h 0m Average total duration 15h 30m Onboard + 30m Additional time* | 4h 23m Average total duration Fastest 2h 23m Onboard + 2h 0m Additional time* | 10h 14m Average total duration (door-to-door) |
0.3 - 0.9kg CO2 emissions Lowest | 1.0 - 2.4kg CO2 emissions | 2.9 - 5.7kg CO2 emissions | - CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Syracuse, NY to Chicago, IL:
A bus is $49 less than a train for this route with tickets for a train from Syracuse, NY to Chicago, IL costing on average $155.
A bus is $131 less than a flight for this route with tickets for a flight from Syracuse, NY to Chicago, IL costing on average $237.
Other travel options to Chicago, IL take longer:
Train takes on average 13h 36m.
Bus takes on average 16h 0m.
Tickets start at around $155 compared to roughly $201 in fuel and tolls — a saving of about $46. The journey takes 13h 6m versus 10h 14m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
Travel optionsfrom Syracuse, NY to Chicago, IL
How to get from Syracuse, NY to Chicago, IL by train, bus or flight.
Our recommendation
The best way to travel from Syracuse, NY to Chicago, IL is by taking a bus because it’s the best combination of price and speed.
· 7:35 PM15h25Syracuse, Walsh Cir (Syracuse Bus Station), NY10:00 AMChicago, Greyhound Bus Station$941One-way1 transfer
Cheapest
· 7:35 PM15h25Syracuse, Walsh Cir (Syracuse Bus Station), NY10:00 AMChicago, Greyhound Bus Station$941One-way1 transfer
Fastest
· 7:35 PM15h25Syracuse, Walsh Cir (Syracuse Bus Station), NY10:00 AMChicago, Greyhound Bus Station$941One-way1 transfer
Other options
· · 4:30 AM16h35Syracuse, Walsh Cir (Syracuse Bus Station), NY8:05 PMChicago, Greyhound Bus Station$951One-way2 transfers
· · · 4:30 AM28h30Syracuse, Walsh Cir (Syracuse Bus Station), NY8:00 AMChicago, Union Station (Amtrak), IL$991One-way4 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
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FAQs: Travel from Syracuse, NY to Chicago, IL
Travel to Chicago, IL easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Syracuse, NY to Chicago, IL.

This is compared to other travel options from Syracuse, NY to Chicago, IL:
A bus is $49 less than a train for this route with tickets for a train from Syracuse, NY to Chicago, IL costing on average $155.
A bus is $131 less than a flight for this route with tickets for a flight from Syracuse, NY to Chicago, IL costing on average $237.
Other travel options to Chicago, IL take longer:
Train takes on average 13h 36m.
Bus takes on average 16h 0m.
- Around 46 flights per day.
- Around 4 buses per day.
- Around 2 trains per day.
However, we recommend checking specific travel dates for your route between Syracuse, NY and Chicago, IL as scheduled services by train, bus, and flight can vary by season or day of the week.
- Flights mostly depart from Syracuse Hancock International Airport and arrive in O'Hare International Airport.
- Trains mostly depart from Syracuse Station, Syracuse, NY and arrive in Chicago Union Station, Chicago, IL.
- Buses mostly depart from Syracuse, Walsh Cir (Syracuse Bus Station), NY and arrive in Chicago, Greyhound Bus Station.
- Travel with Greyhound to go to Chicago, IL by bus.
- Travel with Amtrak to go to Chicago, IL by train.
- Travel with United to go to Chicago, IL by flight.
- 2 direct trains per day with Amtrak.
- 4 direct flights per day with United.
Travelling from Syracuse, NY to Chicago, IL: related information
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