Travel Information
Compare train, bus, and flight for Madrid to Pisa
Omio recommends booking the flight as it is the most popular option from Madrid to Pisa among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $174 For those with little time, consider booking a flight, which has an average total journey time of 6h 36m. If you are seeking to minimise your carbon footprint, the bus is your best option, with estimated CO2 emissions of 1.2 - 3.0kg. Average ticket prices depend on the travel mode: a bus costs an average of $174, while a flight costs an average of $531.
Distance: 757 miles (1219 km)
Compare flight with
Most popular Flight | Bus | Driving |
|---|---|---|
$531 Average price | $174 Average price Cheapest | $315 Average price (fuel + tolls) |
6h 36m Average total duration Fastest 4h 36m Onboard + 2h 0m Additional time* | 29h 45m Average total duration 29h 15m Onboard + 30m Additional time* | 16h 55m Average total duration (door-to-door) |
3.7 - 7.3kg CO2 emissions | 1.2 - 3.0kg CO2 emissions Lowest | - CO2 emissions |
![]() Most popular airline | ![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Madrid to Pisa:
A bus is $357 (€299) less than a flight for this route with tickets for a flight from Madrid to Pisa costing on average $531 (€444).
Other travel options to Pisa take longer:
Bus takes on average 29h 45m.
You'll arrive about 12h 19m sooner (4h 36m by flight vs 16h 55m by car). Tickets start at around $531 (€444) compared to roughly $315 (€263) in fuel and tolls — a bit more, but you get time back and avoid a long drive.
Driving makes more sense if you're travelling as a group, want flexibility on timing, or plan to stop en route.
Travel optionsfrom Madrid to Pisa
How to get from Madrid to Pisa by train, bus or flight.
Our recommendation
The best way to travel from Madrid to Pisa is by taking a bus because it’s the best combination of price and speed.
FlixBus · FlixBus · FlixBus11:59 PM35h56Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid)11:55 AMPisa, Via delle Fiamme Gialle (Park Pietrasantina)$1771One-way2 transfers
Cheapest
FlixBus · FlixBus · FlixBus11:59 PM35h56Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid)11:55 AMPisa, Via delle Fiamme Gialle (Park Pietrasantina)$1771One-way2 transfers
Fastest
BA7056+
BA6161:25 PM5h55Madrid Barajas Airport7:20 PMPisa International Airport$10181One-way1 transfer
Other options
FlixBus · FlixBus7:05 PM26h50Madrid, Estación Sur de Autobuses9:55 PMPisa, Via delle Fiamme Gialle (Park Pietrasantina)$2101One-way1 transfer
FlixBus · FlixBus · FlixBus8:50 PM33h10Madrid, Estación Sur de Autobuses6:00 AMPisa (Pisamover via San Giusto/Aurelia)$2261One-way2 transfers
FlixBus · FlixBus · FlixBus11:35 PM36h20Madrid, Estación Sur de Autobuses11:55 AMPisa, Via delle Fiamme Gialle (Park Pietrasantina)$2351One-way2 transfers
Regionale 20659 · Regionale Veloce 4134+
W460129:25 AM9h10Madrid Barajas Airport6:35 PMPisa Centrale$2351One-way2 transfers
Regionale 20679 · Regionale Veloce 4136+
W460129:25 AM11h00Madrid Barajas Airport8:25 PMPisa Centrale$2351One-way2 transfers
Regionale 20771+
Intercity 518+
W460129:25 AM9h35Madrid Barajas Airport7:00 PMPisa Centrale$2491One-way2 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
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FAQs: Travel from Madrid to Pisa
Travel to Pisa easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Madrid to Pisa.

This is compared to other travel options from Madrid to Pisa:
A bus is $357 (€299) less than a flight for this route with tickets for a flight from Madrid to Pisa costing on average $531 (€444).
Other travel options to Pisa take longer:
Bus takes on average 29h 45m.
- Around 18 flights per day.
- Around 4 buses per day.
However, we recommend checking specific travel dates for your route between Madrid and Pisa as scheduled services by train, bus, and flight can vary by season or day of the week.
- Flights mostly depart from Madrid Barajas Airport and arrive in Pisa International Airport.
- Buses mostly depart from Madrid, Estación Sur de Autobuses and arrive in Pisa, Via delle Fiamme Gialle (Park Pietrasantina).
- Travel with Malta Air, Ryanair, KLM, KLM Cityhopper, Air Europa, Swiss, BA Cityflyer, Brussels Airlines, Air France, Lufthansa City Airlines, Lufthansa, Norwegian Air Shuttle, Air Baltic, Helvetic Airways, ITA, British Airways, Iberia to go to Pisa by flight.
- Travel with FlixBus to go to Pisa by bus.
- 1 direct flights per day with Malta Air, Ryanair.
Travelling from Madrid to Pisa: related information
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