The cheapest and fastest trains from University City, MO to Chicago, IL
Cheapest price
$41
Average price
$41
Fastest journey
4 h 11 m
Average duration
4 h 11 m
Trains per day
1
Distance
421 km
The best way to find a cheap train ticket from University City, MO to Chicago, IL is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from University City, MO to Chicago, IL will cost around $41 if you buy it on the day, but the cheapest tickets can be found for only $41.
Of the 1 trains that leave University City, MO for Chicago, IL on Wed, Feb 25, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Wed, Feb 25 the direct trains cover the 421 km distance in an average of 4 h 11 m but if you time it right, some trains will get you there in just 4 h 11 m .
On Wed, Feb 25 the slowest trains will take 4 h 11 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Travel Information
Compare bus, train, and flight for University City, MO to Chicago, IL
Omio recommends booking the train as it is the most popular option from University City, MO to Chicago, IL among Omio's users. If you are prioritising price take the train with prices starting from $27. For those with little time consider booking a flight which can get you there in 1h 36m. The ticket price range depends on the travel mode: a train costs an average of $27, and a flight costs an average of $221.
Distance: 261 miles (421 km)
Compare train with
Most popular Train | Flight | Bus |
|---|---|---|
$44 Average price Cheapest | $361 Average price | $80 Average price |
5h 25m Average total duration 4h 55m Onboard + 30m Additional time* | 4h 36m Average total duration Fastest 1h 36m Onboard + 3h 0m Additional time* | 8h 36m Average total duration 8h 6m Onboard + 30m Additional time* |
Direct Options | Direct Options | Direct Options |
Compare prices and tickets University City, MO to Chicago, IL by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Feb 25
Feb 26
Feb 27
Feb 28
Mar 01
Mar 02
Mar 03
Journey information
Overview: Train from University City, MO to Chicago, IL
Trains from University City, MO to Chicago, IL run on average 12 times per day, taking around 4h 55m. Cheap train tickets for this journey start at $27 (€22) if you book in advance.
There are 9 trains per day. The earliest train runs at 07:15, the last at 20:05. The fastest train covers the 261 miles (421 km) distance in 4h 11m.
Distance 261 miles (421 km) |
Average train duration 4h 55m |
Cheapest ticket price $27 (€22) |
Trains per day 12 |
Direct trains 9 |
Fastest train 4h 11m |
First train 07:15 |
Last train 20:05 |
Train companies: Amtrak from University City, MO to Chicago, IL trainsAmtrak trains will get you between University City, MO and Chicago, IL from $27 (€22). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Amtrak
FAQs: Trains from University City, MO to Chicago, IL
Find answers to the most common questions about traveling from University City, MO to Chicago, IL by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Chicago, IL, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from University City, MO to Chicago, IL
- 5:00 AM - 12:00 AM Monday - Sunday
- Free
- The car park is open 7 days a week from 5:00 a.m. to 12:00 a.m. Departures can be made outside of opening hours. Access via Canal Street.
- The Chicago Firehouse Restaurant
- Lou Mitchell's
- Outside the main entrance.
- Elevators, ramps, restrooms.
- $1
- The Kimpton Gray Hotel
- JW Marriott Chicago
- W Chicago - City Center
- Located in the main hall
- Located in the main hall
- Avis
- Budget
- Enterprise
- Located in the main hall
- Free
- Hall 1: main entrance, Amtrak services
- Hall 2: Metra services
- Hall 3: food court and retail shops
- Bus: Several lines available
- CTA: Blue Line, Pink Line
More options for your journey from University City, MO to Chicago, IL
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