The cheapest and fastest trains from University City, MO to Chicago, IL
Cheapest price
$136
Average price
$136
Fastest journey
5 h 39 m
Average duration
6 h 19 m
Trains per day
5
Distance
421 km
The best way to find a cheap train ticket from University City, MO to Chicago, IL is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from University City, MO to Chicago, IL will cost around $136 if you buy it on the day, but the cheapest tickets can be found for only $136.
It's difficult to get from University City, MO to Chicago, IL without transferring at least once.










Travel Information
Compare bus and train for University City, MO to Chicago, IL
Omio recommends booking the train as it is the most popular option from University City, MO to Chicago, IL among Omio's users. If you are prioritising price take the train with prices starting from €33. For those with little time consider booking a flight which can get you there in 1h 22m. The ticket price range depends on the travel mode: a train costs an average of €33, and a flight costs an average of €327.
Distance: 261 miles (421 km)
Compare train with
Most popular Train | Bus | Flight |
|---|---|---|
€33 Average price Cheapest | €40 Average price | €327 Average price |
5h 25m Average total duration 4h 55m Onboard + 30m Additional time* | 12h 40m Average total duration 12h 10m Onboard + 30m Additional time* | 4h 22m Average total duration Fastest 1h 22m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
Live departures
University City, MO to Chicago, IL train times
The table below shows live departures for University City, MO to Chicago, IL trains for today, Friday, November 7. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 12:51 AM University City, MO | 8h34 | 9:25 AM Chicago, IL | 1 transfer | |
![]() | 6:01 AM University City, MO | 5h39 | 11:40 AM Chicago, IL | 1 transfer | |
![]() | 7:41 AM University City, MO | 6h03 | 1:44 PM Chicago, IL | 1 transfer | |
![]() | 2:21 PM University City, MO | 5h39 | 8:00 PM Chicago, IL | 1 transfer | |
![]() | 5:01 PM University City, MO | 5h42 | 10:43 PM Chicago, IL | 1 transfer |
Find all the dates and times for this journey
Compare prices and tickets University City, MO to Chicago, IL by bus or train
Compare bus and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Nov 08
Nov 09
Nov 10
Nov 11
Nov 12
Nov 13
Nov 14
Journey information
Overview: Train from University City, MO to Chicago, IL
Trains from University City, MO to Chicago, IL run on average 12 times per day, taking around 4h 55m. Cheap train tickets for this journey start at $40 (€33) if you book in advance.
There are 9 trains per day. The earliest train runs at 07:15, the last at 20:05. The fastest train covers the 261 miles (421 km) distance in 4h 11m.
Distance 261 miles (421 km) |
Average train duration 4h 55m |
Cheapest ticket price $40 (€33) |
Trains per day 12 |
Direct trains 9 |
Fastest train 4h 11m |
First train 07:15 |
Last train 20:05 |
Train companies: Amtrak from University City, MO to Chicago, IL trainsAmtrak trains will get you between University City, MO and Chicago, IL from $40 (€33). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Amtrak
FAQs: Trains from University City, MO to Chicago, IL
Find answers to the most common questions about traveling from University City, MO to Chicago, IL by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Chicago, IL, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from University City, MO to Chicago, IL
- 5:00 AM - 12:00 AM Monday - Sunday
- Free
- The car park is open 7 days a week from 5:00 a.m. to 12:00 a.m. Departures can be made outside of opening hours. Access via Canal Street.
- The Chicago Firehouse Restaurant
- Lou Mitchell's
- Outside the main entrance.
- Elevators, ramps, restrooms.
- $1
- The Kimpton Gray Hotel
- JW Marriott Chicago
- W Chicago - City Center
- Located in the main hall
- Located in the main hall
- Avis
- Budget
- Enterprise
- Located in the main hall
- Free
- Hall 1: main entrance, Amtrak services
- Hall 2: Metra services
- Hall 3: food court and retail shops
- Bus: Several lines available
- CTA: Blue Line, Pink Line
More options for your journey from University City, MO to Chicago, IL
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