- Must visit
Art Institute of Chicago
One of the oldest and largest art museums in the US, known for its collection of Impressionist and Post-Impressionist paintings.
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The cheapest and fastest trains from Buffalo, NY to Chicago, IL
Showing times and prices for May 19
Cheapest price
$216
Average price
$926
Fastest journey
10 h 33 m
Average duration
10 h 33 m
Trains per day
2
Distance
729 km
Cheap tickets
The best way to find a cheap train ticket from Buffalo, NY to Chicago, IL is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Buffalo, NY to Chicago, IL will cost around $926 if you buy it on the day, but the cheapest tickets can be found for only $216.
Fast trains
Of the 2 trains that leave Buffalo, NY for Chicago, IL on Tue, May 19, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Tue, May 19 the direct trains cover the 729 km distance in an average of 10 h 33 m but if you time it right, some trains will get you there in just 10 h 33 m .
On Tue, May 19 the slowest trains will take 10 h 33 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
49 Lake Shore Limited12:39 AM10h33Depew Amtrak Station, Depew, NY10:12 AMChicago Union Station, Chicago, IL$2161One-way0 transfers- 449 Lake Shore Limited12:39 AM10h33Depew Amtrak Station, Depew, NY10:12 AMChicago Union Station, Chicago, IL$16351One-way0 transfers
- 49 Lake Shore Limited12:39 AM10h33Depew Amtrak Station, Depew, NY10:12 AMChicago Union Station, Chicago, IL$2161One-way0 transfers
- 449 Lake Shore Limited12:39 AM10h33Depew Amtrak Station, Depew, NY10:12 AMChicago Union Station, Chicago, IL$16351One-way0 transfers
Travel Information
Compare train, bus, and flight for Buffalo, NY to Chicago, IL
Omio recommends booking the train as it is the most popular option from Buffalo, NY to Chicago, IL among Omio's users. If you are prioritising price take the bus with prices starting from $59. For those with little time consider booking a flight which can get you there in 1h 58m. The ticket price range depends on the travel mode: a bus costs an average of $59, and a flight costs an average of $96.
Distance: 452 miles (729 km)
Compare train with
Most popular Train | Bus | Flight | Driving |
|---|---|---|---|
$211 Average price | $119 Average price Cheapest | $364 Average price | $152 Average price (fuel + tolls) |
11h 3m Average total duration 10h 33m Onboard + 30m Additional time* | 14h 3m Average total duration 13h 33m Onboard + 30m Additional time* | 4h 58m Average total duration Fastest 1h 58m Onboard + 3h 0m Additional time* | 7h 50m Average total duration (door-to-door) |
Most popular train company |  Most popular bus company |  Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
The cheapest way to travel from Buffalo, NY to Chicago, IL is a bus with an average price of $119 (€96).
This is compared to other travel options from Buffalo, NY to Chicago, IL:
A bus is $92 (€75) less than a train for this route with tickets for a train from Buffalo, NY to Chicago, IL costing on average $211 (€171).
A bus is $245 (€198) less than a flight for this route with tickets for a flight from Buffalo, NY to Chicago, IL costing on average $364 (€294).
The fastest way to travel from Buffalo, NY to Chicago, IL is by flight with an average journey time of 1h 58m.
Other travel options to Chicago, IL take longer:
Train takes on average 10h 33m.
Bus takes on average 13h 33m.
It's helpful to compare your options as there are 3 ways to travel between Buffalo, NY and Chicago, IL including taking a train, bus, and flight.
We recommend using the train as it is the most popular way to get from Buffalo, NY to Chicago, IL among Omio's users.
Take the train. It's the cheaper option, and the extra time on board is usually more relaxing than driving it.
Tickets start at around $211 (€171) compared to roughly $152 (€123) in fuel and tolls — a saving of about $-59.66 (€-48.20). The journey takes 10h 33m versus 7h 50m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
Live departures
Buffalo, NY to Chicago, IL train times
The table below shows live departures for Buffalo, NY to Chicago, IL trains for tomorrow, Tuesday, May 19. You can also manually refresh the results below to see updated train journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| 449 Lake Shore Limited | 12:39 AM Depew Amtrak Station, Depew, NY | 10h33 | 10:12 AM Chicago Union Station, Chicago, IL | 0 transfersDirect | |
| 49 Lake Shore Limited | 12:39 AM Depew Amtrak Station, Depew, NY | 10h33 | 10:12 AM Chicago Union Station, Chicago, IL | 0 transfersDirect | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Buffalo, NY to Chicago, IL by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Train from Buffalo, NY to Chicago, IL
USAUSA
Trains from Buffalo, NY to Chicago, IL run on average 2 times per day, taking around 10h 33m. Cheap train tickets for this journey start at $58 (€47) if you book in advance.
There are 2 trains per day. The earliest train runs at 00:39, the last at 21:30. The fastest train covers the 452 miles (729 km) distance in 10h 33m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 452 miles (729 km) |
Average train duration 10h 33m |
Cheapest ticket price $58 (€47) |
Trains per day 2 |
Direct trains 2 |
Fastest train 10h 33m |
First train 12:39 AM |
Last train 9:30 PM |
Cheapest Month Nov |
Cheapest Day Sun |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Thu |
Least Busy Day Fri |
Best time to book 14 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Train companies: Amtrak from Buffalo, NY to Chicago, IL trainsAmtrak trains will get you between Buffalo, NY and Chicago, IL from $58 (€47). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Amtrak
About
Amtrak is the main passenger train operator in the United States, providing medium- and long-distance intercity services across 46 states and three Canadian provinces. Operating over 300 trains daily and serving more than 500 destinations, Amtrak connects cities and regions nationwide through routes such as the high-speed Acela in the Northeast Corridor, the scenic Coast Starlight along the West Coast, and the Empire Builder linking Chicago to the Midwest and the Pacific Northwest. Other notable services include the Northeast Regional, Keystone Service, and the unique Auto Train, which allows passengers to bring their cars onboard. Amtrak offers a variety of classes to suit different budgets and travel needs, including Coach, Business, First Class, and Sleeper Class with options like Roomettes, Bedrooms, and Bedroom Suites for overnight journeys. Ticket types include Saver, Value, Flexible, Business, and Premium. Onboard amenities vary by service but may include comfortable seating, Wi-Fi, power outlets, dining options, and lounge access on select trains. Popular routes include Washington, D.C.–Boston, San Diego–San Luis Obispo, San Jose–Sacramento, and Chicago–Seattle.
Luggage & cancellation policy
Average Duration
10h 33m
Cheapest Price
$58 (€47)
Amtrak frequency
2 a day
Luggage included
2 personal items and 2 carry-on bags included free
Luggage storage
Overhead racks, under seats, and designated luggage areas at end of cars
Cancellation Policy
Cancellation policies depend on ticket type and timing
Refund
Full refund if train is canceled by Amtrak
Amenities on board the train
Wifi
Food sold onboard
Café car with snacks, beverages, and light meals. Long-distance trains have full-service dining cars
Seat reservation
Included in ticket price for Business and First Class. Optional fee for Coach Class
Toilets
USB plugs
Accessibility
Wheelchair spaces, accessible restrooms, Red Cap assistance service, accessible platforms and stations
Pets
Small pets under 20 pounds allowed for $26 fee. Must be in carrier. Service animals travel free
Quiet zone
Complete guide to Chicago
Things to do in Chicago
Discover the best of Chicago — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Chicago trip today.
- Recommended
Museum of Science and Industry
The largest science museum in the Western Hemisphere, featuring interactive exhibits and a full-size replica coal mine.
- Recommended
Field Museum
A natural history museum notable for housing Sue, the most complete T. rex skeleton ever discovered.
- Must visit
The Magnificent Mile
A premier commercial district, offering luxury shopping, restaurants, and hotels along Michigan Avenue.
- Must visit
Lincoln Park
Home to attractions like the Lincoln Park Zoo and Conservatory, offering lovely green spaces for walks.
- Must visit
Grant Park
Known as ‘Chicago’s front yard,’ it hosts major events and festivals, and houses Museum Campus.
Deep-Dish Pizza
A thick, pie-like pizza with a buttery crust filled with layers of cheese, meat, and chunky tomato sauce. It's a Chicago staple originating from local pizzerias.
Chicago-Style Hot Dog
An all-beef hot dog served on a poppy seed bun, topped with mustard, onions, relish, pickles, tomatoes, and a dash of celery salt. No ketchup allowed!
Italian Beef Sandwich
Thin slices of seasoned roast beef, served in a long French roll soaked in au jus and often topped with giardiniera or green peppers.
Alinea
Famed for its molecular gastronomy and creatively served dishes, providing an unforgettable fine dining experience.
Lou Malnati's Pizzeria
A classic spot to try Chicago's renowned deep-dish pizza in a casual setting. Known for its buttery crust and generous toppings.
Portillo's
A famous chain known for Chicago-style hot dogs, Italian beef sandwiches, and chocolate cake shakes in a lively, diner-like atmosphere.
United States Dollar
Prices are moderate for a major U.S. city; accommodation is reasonable, but dining can vary widely based on choice.
Average meal costs
- Budget
- $10-20 for fast food or casual dining.
- Mid-range
- $25-50 per person for a typical restaurant.
- Fine dining
- $70+ per person for upscale dining.
- Coffee
- $3-5 for a coffee.
Tipping culture
15-20% in restaurants, $1-2 per drink at bars, and round up for taxis.
Traveling by train from Buffalo, NY to Chicago, IL
The train connection between Buffalo, NY and Chicago, IL is a convenient option for travelers looking to explore these vibrant cities. Operated by Amtrak, the journey offers comfortable seating and scenic views along the way. With multiple departures daily, passengers can easily plan their trip while enjoying onboard amenities that make travel enjoyable. Whether you're heading to Buffalo's rich history or Chicago's bustling urban landscape, this rail service provides an efficient link between two iconic American destinations.
Train Connection: Buffalo, NY to Chicago, IL
The train journey from Buffalo, NY to Chicago, IL takes approximately 10 hours and 33 minutes. There is 1 connection per day for this route; however, the trains are not direct. Passengers can expect a layover of about 1 hour and 53 minutes during their trip.
Buffalo, NY to Chicago, IL
The first daily train journey departs from Buffalo at 4:39 AM and arrives in Chicago at 5:39 AM. This early morning connection allows travelers to start their day with a scenic ride between these two cities.
Train Tickets Price for Buffalo, NY to Chicago, IL
The cheapest ticket price for the train connection from Buffalo to Chicago is $66 (59.4€). The average ticket price tends to be around $113 (101.7€), making it a good option for budget-conscious travelers looking to explore these vibrant cities.
Exploring Chicago's Iconic Landmarks
Welcome to the Willis Tower, formerly known as the Sears Tower, which was completed in 1973 and held the title of the tallest building in the world for nearly 25 years. This iconic skyscraper not only symbolizes Chicago's architectural innovation but also offers breathtaking views from its Skydeck on the 103rd floor, where you can step out onto glass ledges that extend four feet outside of the building! As we explore this landmark, you'll discover how it has become a vital part of Chicago’s skyline and an essential stop for anyone wanting to experience our city's grandeur.
Next up is Millennium Park, inaugurated in 2004 as a vibrant urban oasis that showcases art and culture at every turn. The park features unique attractions like Cloud Gate—affectionately known as "The Bean"—which reflects both visitors and stunning cityscapes while serving as a gathering place for locals and tourists alike. With its lush gardens, interactive fountains, and outdoor concert venues such as Jay Pritzker Pavilion, Millennium Park truly embodies Chicago's spirit of creativity and community engagement.
Finally, let’s head over to Navy Pier—a historic waterfront destination opened in 1916 that stretches along Lake Michigan with endless entertainment options. It boasts unique features like rides at Pier Park—including one of America's largest Ferris wheels—and hosts cultural events throughout the year at places like Aon Grand Ballroom or Chicago Shakespeare Theater. Whether you're looking to enjoy scenic boat tours or indulge your taste buds with local cuisine at various eateries along this lively pier area, Navy Pier promises unforgettable experiences against a backdrop of beautiful lakefront views.
FAQs: Trains from Buffalo, NY to Chicago, IL
Find answers to the most common questions about traveling from Buffalo, NY to Chicago, IL by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Chicago, IL, this guide helps you travel smarter and with confidence.
Train ticket prices from Buffalo, NY to Chicago, IL can vary. The cheapest ticket starts at $58 (€47), while the average price is around $211 (€171).
The train from Buffalo, NY to Chicago, IL takes 10h 33m and runs 2 per day.
The distance by train from Buffalo, NY to Chicago, IL is 452 miles (729 km).
The first train from Buffalo, NY to Chicago, IL leaves at 12:39 AM.
The last train from Buffalo, NY to Chicago, IL leaves at 9:30 PM.
There is no high speed train available from Buffalo, NY to Chicago, IL.
Yes, there is a direct train from Buffalo, NY to Chicago, IL. This service operates 2 times per day, provided by Amtrak.
Unfortunately, there is no night train available from Buffalo, NY to Chicago, IL.
The train station in Buffalo, NY that goes to Chicago, IL is Depew Amtrak Station, Depew, NY, which connects to Chicago Union Station, Chicago, IL.
The cheapest way to get from Buffalo, NY to Chicago, IL is by train, with a cost of around $58 (€47).
The train journey from Buffalo, NY to Chicago, IL offers scenic views of the Great Lakes region, with sights of Lake Erie and lush landscapes, particularly during the fall when the foliage is vibrant.
A day trip from Buffalo, NY to Chicago, IL is not feasible as the travel time is 10h 33m. Trains operate twice per day, and the distance is 452 miles (729 km).
In Chicago, IL, you can explore the Museum of Science and Industry and its interactive exhibits, enjoy the vibrant neighborhoods like Wicker Park and Lincoln Park, take a river cruise to view iconic architecture, and attend a live performance at the historic Chicago Theatre. Visit Lincoln Park Zoo for a free and enjoyable day. For sights, don't miss Millennium Park with its modern art, the renowned Art Institute of Chicago, the entertainment hub of Navy Pier, panoramic views from Willis Tower Skydeck, and the fascinating exhibits at the Field Museum.
To fully experience Chicago, IL, plan for at least 3-4 days to visit key attractions such as Millennium Park, The Art Institute of Chicago, Navy Pier, and explore diverse neighborhoods.
Yes, you can take the train from Buffalo, NY to Chicago, IL.
Since neither Buffalo, NY nor Chicago, IL are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
Popular day trips by train from Chicago, IL include Milwaukee, WI, South Bend, IN, New Buffalo, MI, Racine, WI, Elkhart, IN.
We recommend using the train as it is the most popular way to get from Buffalo, NY to Chicago, IL among Omio's users.
Items not allowed on trains typically include hazardous materials such as explosives, flammable liquids, corrosive substances, and illegal drugs. Additionally, large or bulky items that may obstruct aisles or emergency exits, as well as pets without proper carriers, may be restricted. Specific prohibited items can vary by train operator and region, so please check the rules for your particular journey.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Chicago, IL, travelers should be cautious of pickpocketing and purse snatching, especially in crowded areas like public transit and popular tourist spots. Common scams include fake charity solicitations and distraction thefts. It is advisable to stay alert in neighborhoods outside downtown after dark and use authorized transportation services to avoid unlicensed taxi scams. Keeping valuables secure and being aware of surroundings helps mitigate these risks.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular train stations
Popular train stations from Buffalo, NY to Chicago, IL
Buffalo
Chicago
Amenities at train station
Wifi
Lockers
Parking
Dining
ATM
Taxis
Accessibility
WC
Hotel
Lounge
Lost and Found Office
Ticket Office
Bike Parking
Car Rental
Information Desk
Luggage Cartsinformation
Ticket Office Hours
- 5:00 AM - 12:00 AM Monday - Sunday
Distance to city center
3 km
Number of platforms
24Wifi
- Free
Parking
- The car park is open 7 days a week from 5:00 a.m. to 12:00 a.m. Departures can be made outside of opening hours. Access via Canal Street.
Dining
- The Chicago Firehouse Restaurant
- Lou Mitchell's
Taxis
- Outside the main entrance.
Accessibility
- Elevators, ramps, restrooms.
WC
- $1
Hotel
- The Kimpton Gray Hotel
- JW Marriott Chicago
- W Chicago - City Center
Lounge
- Located in the main hall
Lost and Found Office
- Located in the main hall
Car Rental
- Avis
- Budget
- Enterprise
Information Desk
- Located in the main hall
Luggage Carts
- Free
Station Plan
- Hall 1: main entrance, Amtrak services
- Hall 2: Metra services
- Hall 3: food court and retail shops
Public transit options for Union Station
- Bus: Several lines available
- CTA: Blue Line, Pink Line
Most popular train connections from Buffalo, NY
More options for your journey from Buffalo, NY to Chicago, IL
Here are some other resources that might have the information you need
Most popular trains to and from Chicago, IL and Buffalo, NY
Most popular train connections to Chicago, IL
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