- Must visit
Museo Nazionale del Paleolitico di Isernia
Major Paleolithic museum beside the renowned prehistoric site. Essential for understanding early human settlement in Europe.
Cheapest price on Sep 18
$11
Average ticket price on Sep 18
$12
Fastest journey on Sep 18
1 h 59 m
Average journey duration on Sep 18
2 h 9 m
Trains on Sep 18
5
Distance
85 km
The best way to find a cheap train ticket from Naples to Isernia is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Naples to Isernia will cost around $12 if you buy it on the day, but the cheapest tickets can be found for only $11.
On Fri, Sep 18, we found 5 trains from Naples to Isernia, including 4 direct services.
On Fri, Sep 18 the direct trains cover the 85 km distance in an average of 2 h 9 m but if you time it right, some trains will get you there in just 1 h 59 m .
On Fri, Sep 18 the slowest trains will take 2 h 16 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
Regionale 5190
Regionale 5192
Regionale 5196
Regionale 23495
Regionale 21139 · Regionale 94884
Regionale 5192
Regionale 23495
Regionale 5190
Regionale 5196
Regionale 21139 · Regionale 94884Omio recommends booking the train as it is the most popular option from Naples to Isernia among Omio's users. If you are prioritising price, take the train, with an average ticket price of $15 For those with little time, consider booking a train, which has an average total journey time of 2h 34m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.0 - 0.1kg. Average ticket prices depend on the travel mode: a train costs an average of $15, while a bus costs an average of $17.
Distance: 52 miles (85 km)
Most popular Train | Bus |
|---|---|
$15 Average price Cheapest | $17 Average price |
2h 34m Average total duration Fastest 2h 4m Onboard + 30m Additional time* | 2h 34m Average total duration 2h 4m Onboard + 30m Additional time* |
0.0 - 0.1kg CO2 emissions Lowest | 0.1 - 0.2kg CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company |
Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Naples to Isernia:
A train is $3 less than a bus for this route with tickets for a bus from Naples to Isernia costing on average $17.
Other travel options to Isernia take longer:
Bus takes on average 2h 4m.
The table below shows live departures for Naples to Isernia trains for today, Thursday, September 17. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 11:00 AM Naples | 2h04 | 1:04 PM Isernia | 0 transfersDirect | |
![]() | 5:37 PM Naples | 2h03 | 7:40 PM Isernia | 0 transfersDirect | |
![]() | 6:37 PM Naples | 2h03 | 8:40 PM Isernia | 0 transfersDirect | |
| Friday, September 18 | |||||
Regionale 21139 · Regionale 94884 | 7:04 AM Naples Centrale | 2h16 | 9:20 AM Isernia station | 1 transfer | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Trains from Naples to Isernia run on average 6 times per day, taking around 2h 4m. Cheap train tickets for this journey start at $11 but you can travel from only $8 by bus.
There are 4 trains per day. The earliest train runs at 03:55, the last at 20:35. The fastest train covers the 52 miles (85 km) distance in 1h 21m.
Distance 52 miles (85 km) |
Average train duration 2h 4m |
Cheapest ticket price $11 |
Trains per day 6 |
Direct trains 4 |
Fastest train 1h 21m |
First train 3:55 AM |
Last train 8:35 PM |
Cheapest Month Aug |
Cheapest Day Sat |
High Season Jul - Sep |
Low Season Apr - Jun |
Busiest Day Tue |
Least Busy Day Thu |
Best time to book 1 day |
Discover the best of Isernia — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Isernia trip today.
Major Paleolithic museum beside the renowned prehistoric site. Essential for understanding early human settlement in Europe.
Archaeological area museum presenting finds from the ancient settlement. A strong companion visit to the cathedral and Roman remains.
Exhibition venue in a historic setting, often used for local heritage displays. Good for visitors interested in community-focused culture.
Main historic street lined with palaces, churches, and shops. The best walk for absorbing Isernia's old-town atmosphere.
The historic center preserves medieval lanes, arches, and layered architecture. Ideal for slow exploration and local street photography.
Central square near the cathedral and Fontana Fraterna. A practical starting point for discovering the city's key monuments.
Fresh pasta sheets layered with rich pork ragù, mozzarella, and caciocavallo. A Sunday and feast-day classic in Molise with deep family tradition.
Small handmade cavatelli pasta, often served with tomato sauce, pork, or seasonal vegetables. It is one of Molise’s best-known home-style staples.
Rustic soup of field greens, potatoes, beans, and cornbread or stale bread. A traditional peasant dish from the Isernia area, especially in colder months.
Established restaurant known for Molisan cooking, handmade pasta, and local meats in a refined but welcoming setting.
Well-regarded traditional venue serving regional specialties, grilled meats, and classic local dishes in a rustic atmosphere.
Casual, popular spot for pizza and southern Italian dishes, suited to an easy meal with locals and families.
Moderate for Italy. Hotels and dining are usually cheaper than Rome or Florence, while local buses and coffee remain low-cost for most travelers.
Tipping is modest. Service may be included. Round up or leave 5-10% at restaurants for good service; round up taxi fares; small change is enough at cafes.
Official public transport app
Isernia Railway Station -> Piazza Andrea d'Isernia
Find answers to the most common questions about traveling from Naples to Isernia by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Isernia, this guide helps you travel smarter and with confidence.

Most Naples to Isernia trains use the Napoli Centrale to Isernia station pair. Use this guide to compare Naples and Isernia train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
Napoli Centrale is 2 km from Naples city centre. Public transport options include:
Napoli Centrale has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Ticket Office, Car Rental, and Information Desk.
Food options include: Tentazioni Cafe, Burger King, VyTA Boulangerie, Time Cafè, Caffè Toraldo, Chalet Ciro, Cibiamo, Chef Express, Eccellenze Della Costiera, 100 Montaditos, & more
Free WiFi throughout the station. ATMs are located at various points in the station.
The ticket office is open Mon - Sun: 05:50 - 21:10. Information desks are located on the ground floor in the main concourse.
Luggage storage is kiPoint luggage storage is located close to Platform 2, open daily from 06:00 to 23:00. .
Available at Napoli Centrale: Parking, Taxis, WC.
Available at Napoli Centrale: Car Rental.
Accessibility facilities are available at Napoli Centrale: The station is fully accessible. The Sala Blu office provides services and assists customers with disabilities. .
Nearby hotels include Grand Hotel Europa, Starhotels Terminus, B&B Hotel Napoli.
Napoli, Aeroporto Internazionale is 5 km from Naples city centre. Public transport options include:
Napoli, Aeroporto Internazionale has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Multiple Italian cuisine restaurants on-site.
Free WiFi throughout the station. ATMs are aTMs located near the ticket office.
Ticket office support is available at Napoli, Aeroporto Internazionale.
Available at Napoli, Aeroporto Internazionale: Parking, Taxis, WC.
Accessibility facilities are available at Napoli, Aeroporto Internazionale: Wheelchair-accessible facilities available.
Naples, Beverello - Angioino has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Several restaurants and cafes available.
Free Wi-Fi available in the main areas. ATMs are aTMs available near the entrance.
Ticket office support is available at Naples, Beverello - Angioino.
Available at Naples, Beverello - Angioino: Parking, Taxis, WC.
Accessibility facilities are available at Naples, Beverello - Angioino: Station equipped with elevators and ramps.
Isernia has practical services for this route, including Wifi, Lockers, Parking, Dining, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Information Desk, and Luggage Carts.
Food options include: Pasta e Pizza, Ristorante da Adriano
Free.
Ticket office support is available at Isernia. Information desks are located in the main hall.
Luggage storage is available at Isernia. Lost and found is available at the station.
Available at Isernia: Parking, Taxis, WC.
Available at Isernia: Bike Parking.
Accessibility facilities are available at Isernia: Ramps.
Nearby hotels include Grand Hotel Europa, Hotel Ristorante Sayonara, Hotel La Tequila.
Here are some other resources that might have the information you need