- Must visit
Vatican Museums
World-famous museum complex with the Sistine Chapel, Raphael Rooms, and major classical and Renaissance collections. Timed entry is strongly recommended due to very high demand.
Cheapest price
$31
Average price
$63
Fastest journey
2 h 13 m
Average duration
2 h 27 m
Trains per day
49
Distance
264 km
The best way to find a cheap train ticket from Pisa Centrale to Rome is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Pisa Centrale to Rome will cost around $63 if you buy it on the day, but the cheapest tickets can be found for only $31.
Of the 49 trains that leave Pisa Centrale for Rome on Sat, Jun 20, 24 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sat, Jun 20 the direct trains cover the 264 km distance in an average of 2 h 27 m but if you time it right, some trains will get you there in just 2 h 13 m .
On Sat, Jun 20 the slowest trains will take 2 h 46 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
Regionale Veloce 4133
Regionale Veloce 4131
Regionale Veloce 4137
Regionale Veloce 4139
Regionale Veloce 4129
FRECCIARGENTO 8583
FRECCIARGENTO 8551
FRECCIARGENTO 8591
FRECCIARGENTO 8583
Regionale 18260+
FRECCIAROSSA 9401Omio recommends booking the train as it is the most popular option from Pisa Centrale to Rome among Omio's users. If you are prioritising price take the bus with prices starting from $12. For those with little time consider booking a train which can get you there in 3h 5m. The ticket price range depends on the travel mode: a bus costs an average of $12, and a train costs an average of $16.
Distance: 164 miles (264 km)
Most popular Train | Bus | Driving |
|---|---|---|
$31 Average price | $23 Average price Cheapest | $83 Average price (fuel + tolls) |
3h 35m Average total duration Fastest 3h 5m Onboard + 30m Additional time* | 5h 23m Average total duration 4h 53m Onboard + 30m Additional time* | 3h 55m Average total duration (door-to-door) |
![]() Most popular train company | ![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Pisa Centrale to Rome:
A bus is $8 (€6) less than a train for this route with tickets for a train from Pisa Centrale to Rome costing on average $31 (€25).
Other travel options to Rome take longer:
Bus takes on average 4h 53m.
The journey is about 50m faster (3h 5m by train vs 3h 55m by car) and roughly $52 (€42) cheaper once you factor in fuel and tolls ($31 (€25) vs $83 (€68)). You'll also arrive in the city centre rather than hunting for parking, and you can work, read, or watch the landscape go by instead of concentrating on the road.
Direct services run with Regionale, Frecciabianca, Intercity, Frecciargento, Frecciarossa, Intercity Notte.
Driving is still worth considering if you want to stop along the way or need a car once you arrive.
The table below shows live departures for Pisa Centrale to Rome trains for today, Friday, June 19. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
Regionale Veloce 4036+ FRECCIAROSSA 8419 | 1:32 PM Pisa Centrale | 2h52 | 4:24 PM Rome Termini | 1 transfer | |
Regionale Veloce 4133 | 1:35 PM Pisa Centrale | 4h16 | 5:51 PM Rome Ostiense | 0 transfersDirect | |
FRECCIABIANCA 8613 | 2:07 PM Pisa Centrale | 3h26 | 5:33 PM Rome Termini | 0 transfersDirect | |
Regionale Veloce 4038+ FRECCIAROSSA 9421 | 2:32 PM Pisa Centrale | 2h52 | 5:24 PM Rome Termini | 1 transfer | |
Intercity 511 | 2:53 PM Pisa Centrale | 3h25 | 6:18 PM Rome Termini | 0 transfersDirect | |
Regionale Veloce 4042+ FRECCIAROSSA 9425 | 3:32 PM Pisa Centrale | 2h53 | 6:25 PM Rome Termini | 1 transfer | |
Regionale Veloce 4135 | 3:37 PM Pisa Centrale | 4h25 | 8:02 PM Rome Ostiense | 0 transfersDirect | |
Regionale 18308+ Intercity 597 | 4:01 PM Pisa Centrale | 5h06 | 9:07 PM Rome Tiburtina | 1 transfer | |
Regionale Veloce 4044+ FRECCIAROSSA 9427 | 4:32 PM Pisa Centrale | 2h53 | 7:25 PM Rome Termini | 1 transfer | |
FRECCIABIANCA 8619 | 5:07 PM Pisa Centrale | 3h26 | 8:33 PM Rome Termini | 0 transfersDirect | |
Regionale Veloce 4046+ FRECCIAROSSA 8525 | 5:09 PM Pisa Centrale | 3h01 | 8:10 PM Rome Termini | 1 transfer | |
Regionale Veloce 4048+ FRECCIAROSSA 9431 | 5:32 PM Pisa Centrale | 2h53 | 8:25 PM Rome Termini | 1 transfer | |
Regionale Veloce 4137 | 5:37 PM Pisa Centrale | 4h26 | 10:03 PM Rome Termini | 0 transfersDirect | |
Regionale 18401+ FRECCIAROSSA 8527 | 5:54 PM Pisa Centrale | 3h21 | 9:15 PM Rome Termini | 1 transfer | |
Regionale Veloce 4052+ FRECCIAROSSA 9433 | 6:32 PM Pisa Centrale | 2h58 | 9:30 PM Rome Termini | 1 transfer | |
Regionale Veloce 4056+ FRECCIAROSSA 8529 | 7:09 PM Pisa Centrale | 3h06 | 10:15 PM Rome Termini | 1 transfer | |
FRECCIAROSSA 8623 | 7:11 PM Pisa Centrale | 3h22 | 10:33 PM Rome Termini | 0 transfersDirect | |
Regionale Veloce 4058+ FRECCIAROSSA 9435 | 7:32 PM Pisa Centrale | 2h53 | 10:25 PM Rome Termini | 1 transfer | |
Regionale Veloce 4139 | 7:37 PM Pisa Centrale | 4h26 | 12:03 AM Rome Termini | 0 transfersDirect | |
InterCityNotte 795 | 8:11 PM Pisa Centrale | 3h27 | 11:38 PM Rome Ostiense | 0 transfersDirect | |
FRECCIARGENTO 8591 | 8:38 PM Pisa Centrale | 2h23 | 11:01 PM Rome Termini | 0 transfersDirect | |
Regionale 18407+ FRECCIAROSSA 9567 | 8:42 PM Pisa Centrale | 3h12 | 11:54 PM Rome Termini | 1 transfer | |
| Saturday, June 20 | |||||
InterCityNotte 799 | 2:21 AM Pisa Centrale | 3h31 | 5:52 AM Rome Ostiense | 0 transfersDirect | |
Regionale 18250+ Intercity 581 | 4:15 AM Pisa Centrale | 4h10 | 8:25 AM Rome Termini | 1 transfer | |
Regionale 18250+ FRECCIAROSSA 9503 | 4:15 AM Pisa Centrale | 3h34 | 7:49 AM Rome Termini | 1 transfer | |
Regionale 18252+ FRECCIAROSSA 9591 | 5:19 AM Pisa Centrale | 3h16 | 8:35 AM Rome Termini | 1 transfer | |
Regionale Veloce 4125 | 5:37 AM Pisa Centrale | 4h14 | 9:51 AM Rome Ostiense | 0 transfersDirect | |
Regionale 18254+ FRECCIAROSSA 9505 | 5:39 AM Pisa Centrale | 3h25 | 9:04 AM Rome Termini | 1 transfer | |
Regionale 18260+ FRECCIAROSSA 9401 | 6:29 AM Pisa Centrale | 2h46 | 9:15 AM Rome Tiburtina | 1 transfer | |
Intercity 501 | 6:33 AM Pisa Centrale | 3h37 | 10:10 AM Rome Ostiense | 0 transfersDirect | |
FRECCIABIANCA 8601 | 7:07 AM Pisa Centrale | 3h33 | 10:40 AM Rome Termini | 0 transfersDirect | |
FRECCIARGENTO 8583 | 7:33 AM Pisa Centrale | 2h13 | 9:46 AM Rome Tiburtina | 0 transfersDirect | |
FRECCIARGENTO 8583 | 7:33 AM Pisa Centrale | 2h32 | 10:05 AM Rome Termini | 0 transfersDirect | |
Regionale Veloce 4129 | 7:37 AM Pisa Centrale | 4h26 | 12:03 PM Rome Termini | 0 transfersDirect | |
Regionale Veloce 4014+ FRECCIAROSSA 9303 | 7:38 AM Pisa Centrale | 2h57 | 10:35 AM Rome Termini | 1 transfer | |
Regionale 18425+ FRECCIAROSSA 9515 | 7:44 AM Pisa Centrale | 3h05 | 10:49 AM Rome Termini | 1 transfer | |
Regionale 18268+ FRECCIAROSSA 8513 | 7:54 AM Pisa Centrale | 3h20 | 11:14 AM Rome Termini | 1 transfer | |
Regionale 18265 · Regionale 94809 | 8:09 AM Pisa Centrale | 5h54 | 2:03 PM Rome Termini | 1 transfer | |
Regionale Veloce 4016+ FRECCIAROSSA 9405 | 8:32 AM Pisa Centrale | 2h50 | 11:22 AM Rome Termini | 1 transfer | |
FRECCIABIANCA 8605 | 9:07 AM Pisa Centrale | 3h26 | 12:33 PM Rome Termini | 0 transfersDirect | |
FRECCIARGENTO 8551 | 9:15 AM Pisa Centrale | 2h21 | 11:36 AM Rome Termini | 0 transfersDirect | |
Regionale Veloce 4020+ FRECCIAROSSA 9409 | 9:32 AM Pisa Centrale | 2h53 | 12:25 PM Rome Termini | 1 transfer | |
Regionale 18282+ FRECCIAROSSA 8503 | 9:54 AM Pisa Centrale | 3h16 | 1:10 PM Rome Termini | 1 transfer | |
Regionale Veloce 4026+ FRECCIAROSSA 9411 | 10:32 AM Pisa Centrale | 2h58 | 1:30 PM Rome Termini | 1 transfer | |
Intercity 583 | 10:57 AM Pisa Centrale | 3h11 | 2:08 PM Rome Ostiense | 0 transfersDirect | |
Intercity 505 | 11:11 AM Pisa Centrale | 3h37 | 2:48 PM Rome Termini | 0 transfersDirect | |
Regionale Veloce 4030+ FRECCIAROSSA 9413 | 11:30 AM Pisa Centrale | 2h55 | 2:25 PM Rome Termini | 1 transfer | |
Regionale Veloce 4131 | 11:37 AM Pisa Centrale | 4h14 | 3:51 PM Rome Ostiense | 0 transfersDirect | |
Intercity 1589 | 11:46 AM Pisa Centrale | 3h27 | 3:13 PM Rome Ostiense | 0 transfersDirect | |
Regionale Veloce 4032+ FRECCIAROSSA 9415 | 12:32 PM Pisa Centrale | 2h58 | 3:30 PM Rome Termini | 1 transfer | |
Find all the dates and times for this journey
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Trains from Pisa Centrale to Rome run on average 41 times per day, taking around 3h 5m. Cheap train tickets for this journey start at $16 (€13) but you can travel from only $12 (€10) by bus.
There are 18 trains per day. The earliest train runs at 00:21, the last at 19:31. The fastest train covers the 164 miles (264 km) distance in 2h 30m.
Distance 164 miles (264 km) |
Average train duration 3h 5m |
Cheapest ticket price $16 (€13) |
Trains per day 41 |
Direct trains 18 |
Fastest train 2h 30m |
First train 12:21 AM |
Last train 7:31 PM |
Cheapest Month Jan |
Cheapest Day Sat |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Thu |
Least Busy Day Tue |
Discover the best of Rome — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Rome trip today.
World-famous museum complex with the Sistine Chapel, Raphael Rooms, and major classical and Renaissance collections. Timed entry is strongly recommended due to very high demand.
One of Rome’s finest art museums, known for Bernini sculptures and paintings by Caravaggio and Raphael. Advance reservation is typically required because entry is strictly timed.
The city’s historic civic museums on Capitoline Hill, featuring Roman bronzes, imperial sculpture, and art with views over the Forum.
Elegant Baroque square built on an ancient stadium, lined with fountains, palaces, and lively street life. A classic area for strolling and people-watching.
Atmospheric neighborhood of narrow lanes, ivy-covered buildings, and busy evening streets. Popular with visitors but still one of Rome’s most characteristic areas.
Famous monumental staircase linking Piazza di Spagna and Trinità dei Monti. A highly photographed landmark and social-media favorite.
A classic Roman pasta with pecorino Romano and black pepper. It is one of the city’s most iconic dishes and a benchmark of Roman cooking.
Traditional Roman pasta made with guanciale, egg yolk, pecorino Romano, and black pepper. It is famous for its rich sauce without cream.
A beloved pasta sauce of tomato, guanciale, and pecorino Romano, closely tied to Rome’s culinary identity and served with bucatini or rigatoni.
Rome’s most famous fine-dining restaurant, offering elegant tasting menus, panoramic views, and one of the city’s most prestigious dining experiences.
A historic trattoria near the Pantheon, famous for traditional Roman dishes such as gricia, amatriciana, and seasonal specialties.
A celebrated central Rome venue known for classic Roman pasta, exceptional cured meats, and a refined but lively atmosphere.
Rome is moderate by Western Europe standards: sights are affordable, but central hotels and tourist-area dining cost more.
Service is usually included or modest. Tipping is not required, but rounding up or leaving EUR 1-2 at cafes and 5-10% at restaurants for good service is appreciated.
Official public transport app
Rome Termini, Rome -> Piazza Venezia, Rome
Find answers to the most common questions about traveling from Pisa Centrale to Rome by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Rome, this guide helps you travel smarter and with confidence.

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