- Must visit
Vatican Museums
World-famous papal museums with the Sistine Chapel, Raphael Rooms, and major classical collections.
Cheapest price on Sep 19
$32
Average ticket price on Sep 19
$53
Fastest journey on Sep 19
2 h 13 m
Average journey duration on Sep 19
2 h 27 m
Trains on Sep 19
49
Distance
264 km
The best way to find a cheap train ticket from Pisa Centrale to Rome is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Pisa Centrale to Rome will cost around $53 if you buy it on the day, but the cheapest tickets can be found for only $32.
On Sat, Sep 19, we found 49 trains from Pisa Centrale to Rome, including 24 direct services.
On Sat, Sep 19 the direct trains cover the 264 km distance in an average of 2 h 27 m but if you time it right, some trains will get you there in just 2 h 13 m .
On Sat, Sep 19 the slowest trains will take 2 h 42 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
Regionale Veloce 4125
Regionale Veloce 4131
Regionale Veloce 4135
Regionale Veloce 4133
Regionale Veloce 4139
FRECCIARGENTO 8583
FRECCIARGENTO 8551
FRECCIARGENTO 8591
FRECCIARGENTO 8583
Regionale Veloce 4032+
FRECCIAROSSA 9415Omio recommends booking the flight as it is the most popular option from Pisa Centrale to Rome among Omio's users. If you are prioritising price, take the train, with an average ticket price of $29 For those with little time, consider booking a train, which has an average total journey time of 3h 30m. Average ticket prices depend on the travel mode: a train costs an average of $29, while a flight costs an average of $574.
Distance: 164 miles (264 km)
| Train | Most popular Flight | Bus | Driving |
|---|---|---|---|
$29 Average price Cheapest | $574 Average price | $30 Average price | $83 Average price (fuel + tolls) |
3h 30m Average total duration Fastest 3h 0m Onboard + 30m Additional time* | 5h 36m Average total duration 3h 36m Onboard + 2h 0m Additional time* | 5h 39m Average total duration 5h 9m Onboard + 30m Additional time* | 3h 55m Average total duration (door-to-door) |
![]() Most popular train company | ![]() Most popular airline | ![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Pisa Centrale to Rome:
A train is $1 less than a bus for this route with tickets for a bus from Pisa Centrale to Rome costing on average $30.
A train is $545 less than a flight for this route with tickets for a flight from Pisa Centrale to Rome costing on average $574.
Other travel options to Rome take longer:
Flight takes on average 3h 36m.
Bus takes on average 5h 9m.
The journey is about 55m faster (3h 0m by train vs 3h 55m by car) and roughly $54 cheaper once you factor in fuel and tolls ($29 vs $83). You'll also arrive in the city centre rather than hunting for parking, and you can work, read, or watch the landscape go by instead of concentrating on the road.
Direct services run with Intercity, Frecciarossa, Regionale, Intercity Notte, Frecciargento, Frecciabianca.
Driving is still worth considering if you want to stop along the way or need a car once you arrive.
The table below shows live departures for Pisa Centrale to Rome trains for today, Friday, September 18. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
Regionale 18250+ Intercity 581 | 4:15 AM Pisa Centrale | 4h10 | 8:25 AM Rome Termini | 1 transfer | |
Regionale 18250+ FRECCIAROSSA 9503 | 4:15 AM Pisa Centrale | 3h34 | 7:49 AM Rome Termini | 1 transfer | |
Regionale 18252+ FRECCIAROSSA 9591 | 5:19 AM Pisa Centrale | 3h16 | 8:35 AM Rome Termini | 1 transfer | |
Regionale 18254+ FRECCIAROSSA 9505 | 5:39 AM Pisa Centrale | 3h26 | 9:05 AM Rome Termini | 1 transfer | |
Regionale Veloce 4125 | 5:40 AM Pisa Centrale | 4h08 | 9:48 AM Rome Termini | 0 transfersDirect | |
Regionale 18260+ FRECCIAROSSA 9401 | 6:29 AM Pisa Centrale | 2h46 | 9:15 AM Rome Tiburtina | 1 transfer | |
Intercity 501 | 6:47 AM Pisa Centrale | 3h28 | 10:15 AM Rome Ostiense | 0 transfersDirect | |
FRECCIABIANCA 8601 | 7:07 AM Pisa Centrale | 2h56 | 10:03 AM Rome Termini | 0 transfersDirect | |
FRECCIARGENTO 8583 | 7:33 AM Pisa Centrale | 2h13 | 9:46 AM Rome Tiburtina | 0 transfersDirect | |
FRECCIARGENTO 8583 | 7:33 AM Pisa Centrale | 2h37 | 10:10 AM Rome Termini | 0 transfersDirect | |
Regionale Veloce 4014+ FRECCIAROSSA 9303 | 7:38 AM Pisa Centrale | 3h02 | 10:40 AM Rome Termini | 1 transfer | |
Regionale Veloce 4129 · Autobus RM123 · Regionale 12543 | 7:40 AM Pisa Centrale | 6h08 | 1:48 PM Rome Termini | 2 transfers | |
Regionale 18425+ FRECCIAROSSA 9515 | 7:44 AM Pisa Centrale | 3h05 | 10:49 AM Rome Termini | 1 transfer | |
Regionale 18270+ FRECCIAROSSA 8513 | 7:54 AM Pisa Centrale | 3h20 | 11:14 AM Rome Termini | 1 transfer | |
Regionale Veloce 4016+ FRECCIAROSSA 9405 | 8:32 AM Pisa Centrale | 2h50 | 11:22 AM Rome Termini | 1 transfer | |
Regionale Veloce 4016+ Intercity 583 | 8:32 AM Pisa Centrale | 4h55 | 1:27 PM Rome Tiburtina | 1 transfer | |
FRECCIABIANCA 8605 | 9:07 AM Pisa Centrale | 3h26 | 12:33 PM Rome Termini | 0 transfersDirect | |
FRECCIARGENTO 8551 | 9:15 AM Pisa Centrale | 2h19 | 11:34 AM Rome Termini | 0 transfersDirect | |
Regionale Veloce 4020+ FRECCIAROSSA 9409 | 9:32 AM Pisa Centrale | 2h53 | 12:25 PM Rome Termini | 1 transfer | |
Regionale 18282+ FRECCIAROSSA 8503 | 9:54 AM Pisa Centrale | 3h21 | 1:15 PM Rome Termini | 1 transfer | |
Regionale Veloce 4026+ FRECCIAROSSA 9411 | 10:32 AM Pisa Centrale | 3h03 | 1:35 PM Rome Termini | 1 transfer | |
Regionale Veloce 4030+ FRECCIAROSSA 9413 | 11:30 AM Pisa Centrale | 2h55 | 2:25 PM Rome Termini | 1 transfer | |
Regionale Veloce 4131 | 11:40 AM Pisa Centrale | 4h08 | 3:48 PM Rome Termini | 0 transfersDirect | |
Regionale Veloce 4032+ FRECCIAROSSA 9415 | 12:32 PM Pisa Centrale | 2h42 | 3:14 PM Rome Tiburtina | 1 transfer | |
Regionale Veloce 4036+ FRECCIAROSSA 8419 | 1:32 PM Pisa Centrale | 2h52 | 4:24 PM Rome Termini | 1 transfer | |
Regionale Veloce 4133 | 1:38 PM Pisa Centrale | 4h10 | 5:48 PM Rome Termini | 0 transfersDirect | |
FRECCIABIANCA 8613 | 2:07 PM Pisa Centrale | 2h56 | 5:03 PM Rome Termini | 0 transfersDirect | |
Regionale Veloce 4038+ FRECCIAROSSA 9421 | 2:32 PM Pisa Centrale | 2h53 | 5:25 PM Rome Termini | 1 transfer | |
Intercity 511 | 2:53 PM Pisa Centrale | 3h10 | 6:03 PM Rome Termini | 0 transfersDirect | |
Regionale Veloce 4040+ FRECCIAROSSA 8519 | 3:09 PM Pisa Centrale | 3h01 | 6:10 PM Rome Termini | 1 transfer | |
Regionale Veloce 4042+ FRECCIAROSSA 9425 | 3:32 PM Pisa Centrale | 2h53 | 6:25 PM Rome Termini | 1 transfer | |
Regionale Veloce 4135 | 3:40 PM Pisa Centrale | 4h08 | 7:48 PM Rome Termini | 0 transfersDirect | |
Regionale 18308+ Intercity 597 | 4:01 PM Pisa Centrale | 5h06 | 9:07 PM Rome Tiburtina | 1 transfer | |
Regionale Veloce 4044+ FRECCIAROSSA 9427 | 4:32 PM Pisa Centrale | 2h53 | 7:25 PM Rome Termini | 1 transfer | |
FRECCIABIANCA 8619 | 5:07 PM Pisa Centrale | 2h56 | 8:03 PM Rome Termini | 0 transfersDirect | |
Regionale Veloce 4048+ FRECCIAROSSA 9431 | 5:32 PM Pisa Centrale | 2h52 | 8:24 PM Rome Termini | 1 transfer | |
Regionale Veloce 4137 | 5:40 PM Pisa Centrale | 4h08 | 9:48 PM Rome Termini | 0 transfersDirect | |
Regionale 18401+ FRECCIAROSSA 8527 | 5:54 PM Pisa Centrale | 3h21 | 9:15 PM Rome Termini | 1 transfer | |
Regionale Veloce 4052+ FRECCIAROSSA 9433 | 6:32 PM Pisa Centrale | 2h58 | 9:30 PM Rome Termini | 1 transfer | |
Regionale Veloce 4056+ FRECCIAROSSA 8529 | 7:09 PM Pisa Centrale | 3h06 | 10:15 PM Rome Termini | 1 transfer | |
FRECCIAROSSA 8623 | 7:11 PM Pisa Centrale | 3h07 | 10:18 PM Rome Termini | 0 transfersDirect | |
Regionale Veloce 4058+ FRECCIAROSSA 9435 | 7:32 PM Pisa Centrale | 2h53 | 10:25 PM Rome Termini | 1 transfer | |
Regionale Veloce 4139 | 7:40 PM Pisa Centrale | 4h08 | 11:48 PM Rome Termini | 0 transfersDirect | |
InterCityNotte 795 | 8:11 PM Pisa Centrale | 3h12 | 11:23 PM Rome Ostiense | 0 transfersDirect | |
FRECCIARGENTO 8591 | 8:38 PM Pisa Centrale | 2h23 | 11:01 PM Rome Termini | 0 transfersDirect | |
Regionale 18407+ FRECCIAROSSA 9567 | 8:42 PM Pisa Centrale | 3h12 | 11:54 PM Rome Termini | 1 transfer | |
| Saturday, September 19 | |||||
InterCityNotte 799 | 2:21 AM Pisa Centrale | 3h22 | 5:43 AM Rome Ostiense | 0 transfersDirect | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Trains from Pisa Centrale to Rome run on average 87 times per day, taking around 3h 0m. Cheap train tickets for this journey start at $11 if you book in advance.
There are 18 trains per day. The earliest train runs at 00:21, the last at 17:37. The fastest train covers the 164 miles (264 km) distance in 2h 13m.
Distance 164 miles (264 km) |
Average train duration 3h 0m |
Cheapest ticket price $11 |
Trains per day 87 |
Direct trains 18 |
Fastest train 2h 13m |
First train 12:21 AM |
Last train 5:37 PM |
Cheapest Month May |
Cheapest Day Wed |
High Season Apr - Jun |
Low Season Jan - Mar |
Busiest Day Thu |
Least Busy Day Sat |
Best time to book 35 days |
Discover the best of Rome — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Rome trip today.
World-famous papal museums with the Sistine Chapel, Raphael Rooms, and major classical collections.
Outstanding ancient sculpture and mosaic museum housed in the Palazzo dei Conservatori and Palazzo Nuovo.
Celebrated villa museum with Bernini sculptures, Caravaggio paintings, and refined garden setting.
Elegant Baroque square with Bernini's fountains, lively atmosphere, and superb people-watching.
Historic square and gathering place at the Spanish Steps, ideal for classic city views and strolls.
Charming cobbled neighborhood filled with ivy-clad lanes, churches, nightlife, and local character.
Classic Roman pasta with guanciale, egg yolk, Pecorino Romano, and black pepper. A city icon known for rich flavor without cream.
Roman pasta with guanciale, tomato, and Pecorino Romano. A traditional Lazio staple tied to shepherd cooking and bold savory flavor.
Pasta with guanciale, Pecorino Romano, and black pepper. Considered one of Rome's oldest pasta dishes and prized for its simplicity.
Three-Michelin-star dining by Niko Romito at Bulgari Hotel Roma, offering refined Italian tasting menus in an elegant setting.
Historic trattoria in Testaccio known for classic Roman pasta and quinto quarto dishes in a lively, traditional setting.
Popular casual spot famed for Roman-style pizzas and fried starters. Bustling atmosphere and a long-standing local reputation.
Moderate for Europe: stays in central Rome are pricey, but transit is cheap and meals range from affordable pizza to costly tourist-area dining.
Service may be included via coperto or servizio. Round up or leave 5-10% at restaurants if service is good; round up in taxis; small change is fine at cafés.
Official public transport app
Roma Termini -> Piazza Di Spagna, Rome
Find answers to the most common questions about traveling from Pisa Centrale to Rome by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Rome, this guide helps you travel smarter and with confidence.

Most Pisa Centrale to Rome trains use the Pisa Centrale to Roma Termini station pair, with some services arriving at Roma Tiburtina. Use this guide to compare Pisa Centrale and Rome train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
Pisa Centrale has practical services for this route, including Wifi, Lockers, Parking, Dining, Taxis, Accessibility, WC, Hotel, Ticket Office, Bike Parking, Bike Rental, and Information Desk.
Food options include: McDonald's, Panetteria Binario 1
There is free Wi-Fi available at the McDonald's.
The ticket office is open Mon - Sun: 06:00 - 20:30. Information desks are located just outside the station on Piazza Vittorio Emanuele II.
Luggage storage is there is a luggage storage office near the end of Platform 1.
Available at Pisa Centrale: Parking, Taxis, WC.
Available at Pisa Centrale: Bike Parking, Bike Rental.
Accessibility facilities are available at Pisa Centrale: Accessible facilities including barrier-free restrooms, elevators, ramps, and disabled parking. Sala Blu mobility assistance available from 07:45 to 22:30 with advanced one-hour notice.
Nearby hotels include Hotel NH Pisa, Hotel La Pace, Hotel Maria.
Roma Termini is 1 km from Rome city centre. Public transport options include:
Roma Termini has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Ticket Office, Bike Parking, Car Rental, and Information Desk.
Food options include: Acafe, Moka Café, Roadhouse Grill, McDonald's, Gusto, Chef Express, Coop Minimarket, Mercato Centrale
Free WiFi in the station. ATMs are there are ATMs in various locations around the station.
The ticket office is open Mon - Sun: 06:30 - 22:00. Information desks are located near Platform 24.
Luggage storage is provided by KiPoint and located on Platform 24. Open every day from 06:00 to 23:00.
Available at Roma Termini: Parking, Taxis, WC.
Available at Roma Termini: Bike Parking, Car Rental.
Accessibility facilities are available at Roma Termini: The Sala Blu, Trenitalia's office of assistance for disabled travelers, is located next to Platform 1.
Nearby hotels include Archi di Roma Guest House, Gemma di Roma, The Liberty Boutique Hotel.
Roma Ostiense is 2 km from Rome city centre. Public transport options include:
Roma Ostiense has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Car Rental, Information Desk, and Luggage Carts.
Food options include: Ramen Bar Akira, Eataly Roma
Free. ATMs are available in the train station.
Ticket office support is available at Roma Ostiense. Information desks are located in the main hall.
Luggage storage is available at Roma Ostiense. Lost and found is available at the station.
Available at Roma Ostiense: Parking, Taxis, WC.
Available at Roma Ostiense: Bike Parking, Car Rental.
Accessibility facilities are available at Roma Ostiense: Elevators, ramps, restrooms.
Nearby hotels include Hotel Abitart, Hotel San Anselmo, Hotel Villa San Pio.
Roma San Pietro is 2 km from Rome city centre. Public transport options include:
Roma San Pietro has practical services for this route, including Wifi, Lockers, Parking, Dining, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Information Desk, and Luggage Carts.
Food options include: Ristorante La Vittoria, Osteria dei Pontefici
Free.
Ticket office support is available at Roma San Pietro. Information desks are located in the main hall.
Luggage storage is available at Roma San Pietro. Lost and found is available at the station.
Available at Roma San Pietro: Parking, Taxis, WC.
Available at Roma San Pietro: Bike Parking.
Accessibility facilities are available at Roma San Pietro: Elevators, ramps, restrooms.
Nearby hotels include Starhotels Michelangelo Rome, Hotel San Pietro, Hotel Paolo II.
Here are some other resources that might have the information you need