- Must visit
Vatican Museums
World-famous papal museums with the Sistine Chapel, Raphael Rooms, and major classical collections.
The best way to find a cheap train ticket from Pisa Centrale to Rome is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Pisa Centrale to Rome will cost around CHF 41 if you buy it on the day, but the cheapest tickets can be found for only CHF 26.
On Tue, Nov 03, we found 48 trains from Pisa Centrale to Rome, including 20 direct services.
On Tue, Nov 03 the direct trains cover the 264 km distance in an average of 2 h 27 m but if you time it right, some trains will get you there in just 2 h 13 m .
On Tue, Nov 03 the slowest trains will take 2 h 46 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
Regionale Veloce 4135
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Regionale Veloce 4131
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Regionale Veloce 4137
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Regionale Veloce 4125
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Regionale Veloce 4129 · Autobus RM123 · Regionale 12543
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FRECCIARGENTO 8583
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FRECCIAROSSA 8551
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FRECCIARGENTO 8591
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FRECCIARGENTO 8583
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Regionale 18260+
FRECCIAROSSA 9401
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Trains from Pisa Centrale to Rome run on average 73 times per day, taking around 3h 2m. Cheap train tickets for this journey start at CHF 10 if you book in advance.
There are 18 trains per day. The earliest train runs at 00:21, the last at 19:27. The fastest train covers the 164 miles (264 km) distance in 2h 13m.
Plan this route
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Pisa Centrale to Rome.
The table below shows live departures for Pisa Centrale to Rome trains for today, Monday, November 2. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
Regionale Veloce 4020+ FRECCIAROSSA 9409 | 9:32 AM Pisa Centrale | 2h53 | 12:25 PM Rome Termini | 1 transfer | |
Regionale 18282+ FRECCIAROSSA 8503 | 9:54 AM Pisa Centrale | 3h16 | 1:10 PM Rome Termini | 1 transfer | |
Regionale Veloce 4026+ FRECCIAROSSA 9411 | 10:32 AM Pisa Centrale | 2h58 | 1:30 PM Rome Termini | 1 transfer | |
Intercity 505 | 11:11 AM Pisa Centrale | 3h22 | 2:33 PM Rome Termini | 0 transfersDirect | |
Regionale Veloce 4030+ FRECCIAROSSA 9413 | 11:30 AM Pisa Centrale | 2h55 | 2:25 PM Rome Termini | 1 transfer | |
Regionale Veloce 4131 | 11:45 AM Pisa Centrale | 4h03 | 3:48 PM Rome Termini | 0 transfersDirect | |
Regionale Veloce 4032+ FRECCIAROSSA 9415 | 12:32 PM Pisa Centrale | 2h58 | 3:30 PM Rome Termini | 1 transfer | |
Regionale Veloce 4036+ FRECCIAROSSA 8419 | 1:32 PM Pisa Centrale | 2h52 | 4:24 PM Rome Termini | 1 transfer | |
Regionale Veloce 4133 | 1:43 PM Pisa Centrale | 4h05 | 5:48 PM Rome Termini | 0 transfersDirect | |
FRECCIABIANCA 8613 | 2:07 PM Pisa Centrale | 2h56 | 5:03 PM Rome Termini | 0 transfersDirect | |
Regionale Veloce 4038+ FRECCIAROSSA 9421 | 2:32 PM Pisa Centrale | 2h52 | 5:24 PM Rome Termini | 1 transfer | |
Intercity 511 | 2:53 PM Pisa Centrale | 3h10 | 6:03 PM Rome Termini | 0 transfersDirect | |
Regionale Veloce 4042+ FRECCIAROSSA 9425 | 3:32 PM Pisa Centrale | 2h53 | 6:25 PM Rome Termini | 1 transfer | |
Regionale Veloce 4135 | 3:45 PM Pisa Centrale | 4h03 | 7:48 PM Rome Termini | 0 transfersDirect | |
Regionale 18308+ Intercity 597 | 4:01 PM Pisa Centrale | 5h06 | 9:07 PM Rome Tiburtina | 1 transfer | |
Regionale Veloce 4044+ FRECCIAROSSA 9427 | 4:32 PM Pisa Centrale | 2h53 | 7:25 PM Rome Termini | 1 transfer | |
FRECCIABIANCA 8619 | 5:07 PM Pisa Centrale | 2h56 | 8:03 PM Rome Termini | 0 transfersDirect | |
Regionale Veloce 4048+ FRECCIAROSSA 9431 | 5:32 PM Pisa Centrale | 2h53 | 8:25 PM Rome Termini | 1 transfer | |
Regionale Veloce 4137 | 5:45 PM Pisa Centrale | 4h03 | 9:48 PM Rome Termini | 0 transfersDirect | |
Regionale 18401+ FRECCIAROSSA 8527 | 5:54 PM Pisa Centrale | 3h21 | 9:15 PM Rome Termini | 1 transfer | |
Regionale Veloce 4052+ FRECCIAROSSA 9433 | 6:32 PM Pisa Centrale | 2h58 | 9:30 PM Rome Termini | 1 transfer | |
Regionale Veloce 4056+ FRECCIAROSSA 8529 | 7:09 PM Pisa Centrale | 3h06 | 10:15 PM Rome Termini | 1 transfer | |
FRECCIAROSSA 8623 | 7:11 PM Pisa Centrale | 3h07 | 10:18 PM Rome Termini | 0 transfersDirect | |
Regionale Veloce 4058+ FRECCIAROSSA 9435 | 7:32 PM Pisa Centrale | 2h53 | 10:25 PM Rome Termini | 1 transfer | |
Regionale 4139 | 7:40 PM Pisa Centrale | 4h10 | 11:50 PM Rome Termini | 0 transfersDirect | |
InterCityNotte 795 | 8:11 PM Pisa Centrale | 3h12 | 11:23 PM Rome Ostiense | 0 transfersDirect | |
FRECCIARGENTO 8591 | 8:38 PM Pisa Centrale | 2h23 | 11:01 PM Rome Termini | 0 transfersDirect | |
Regionale 18407+ FRECCIAROSSA 9567 | 8:42 PM Pisa Centrale | 3h12 | 11:54 PM Rome Termini | 1 transfer | |
| Tuesday, November 3 | |||||
InterCityNotte 799 | 2:21 AM Pisa Centrale | 3h22 | 5:43 AM Rome Ostiense | 0 transfersDirect | |
Regionale 18250+ Intercity 581 | 4:15 AM Pisa Centrale | 4h10 | 8:25 AM Rome Termini | 1 transfer | |
Regionale 18250+ FRECCIAROSSA 9503 | 4:15 AM Pisa Centrale | 3h34 | 7:49 AM Rome Termini | 1 transfer | |
Regionale 18252+ FRECCIAROSSA 9591 | 5:19 AM Pisa Centrale | 3h16 | 8:35 AM Rome Termini | 1 transfer | |
Regionale 18254+ FRECCIAROSSA 9505 | 5:39 AM Pisa Centrale | 3h25 | 9:04 AM Rome Termini | 1 transfer | |
Regionale Veloce 4125 | 5:45 AM Pisa Centrale | 4h03 | 9:48 AM Rome Termini | 0 transfersDirect | |
Regionale 18260+ FRECCIAROSSA 9401 | 6:29 AM Pisa Centrale | 2h46 | 9:15 AM Rome Tiburtina | 1 transfer | |
Intercity 501 | 6:47 AM Pisa Centrale | 3h28 | 10:15 AM Rome Ostiense | 0 transfersDirect | |
FRECCIABIANCA 8601 | 7:07 AM Pisa Centrale | 2h56 | 10:03 AM Rome Termini | 0 transfersDirect | |
FRECCIARGENTO 8583 | 7:33 AM Pisa Centrale | 2h13 | 9:46 AM Rome Tiburtina | 0 transfersDirect | |
FRECCIARGENTO 8583 | 7:33 AM Pisa Centrale | 2h32 | 10:05 AM Rome Termini | 0 transfersDirect | |
Regionale Veloce 4014+ FRECCIAROSSA 9303 | 7:38 AM Pisa Centrale | 2h57 | 10:35 AM Rome Termini | 1 transfer | |
Regionale 18425+ FRECCIAROSSA 9515 | 7:44 AM Pisa Centrale | 3h05 | 10:49 AM Rome Termini | 1 transfer | |
Regionale Veloce 4129 · Autobus RM123 · Regionale 12543 | 7:45 AM Pisa Centrale | 6h03 | 1:48 PM Rome Termini | 2 transfers | |
Regionale 18270+ FRECCIAROSSA 8513 | 7:54 AM Pisa Centrale | 3h20 | 11:14 AM Rome Termini | 1 transfer | |
Regionale Veloce 4016+ Intercity 583 | 8:32 AM Pisa Centrale | 4h55 | 1:27 PM Rome Tiburtina | 1 transfer | |
Regionale Veloce 4016+ FRECCIAROSSA 9405 | 8:32 AM Pisa Centrale | 2h50 | 11:22 AM Rome Termini | 1 transfer | |
FRECCIABIANCA 8605 | 9:07 AM Pisa Centrale | 3h11 | 12:18 PM Rome Termini | 0 transfersDirect | |
FRECCIAROSSA 8551 | 9:15 AM Pisa Centrale | 2h21 | 11:36 AM Rome Termini | 0 transfersDirect | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Trains from Pisa Centrale to Rome with Italo, Frecciarossa, and Regionale. Night trains available on this route with Intercity Notte. High-speed trains available on this route with Italo, Frecciarossa, and Frecciabianca. Regional trains available on this route with Regionale. Use the details below to compare onboard facilities.
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
Discover the best of Rome — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Rome trip today.
World-famous papal museums with the Sistine Chapel, Raphael Rooms, and major classical collections.
Outstanding ancient sculpture and mosaic museum housed in the Palazzo dei Conservatori and Palazzo Nuovo.
Celebrated villa museum with Bernini sculptures, Caravaggio paintings, and refined garden setting.
Elegant Baroque square with Bernini's fountains, lively atmosphere, and superb people-watching.
Historic square and gathering place at the Spanish Steps, ideal for classic city views and strolls.
Charming cobbled neighborhood filled with ivy-clad lanes, churches, nightlife, and local character.
Classic Roman pasta with guanciale, egg yolk, Pecorino Romano, and black pepper. A city icon known for rich flavor without cream.
Roman pasta with guanciale, tomato, and Pecorino Romano. A traditional Lazio staple tied to shepherd cooking and bold savory flavor.
Pasta with guanciale, Pecorino Romano, and black pepper. Considered one of Rome's oldest pasta dishes and prized for its simplicity.
Three-Michelin-star dining by Niko Romito at Bulgari Hotel Roma, offering refined Italian tasting menus in an elegant setting.
Historic trattoria in Testaccio known for classic Roman pasta and quinto quarto dishes in a lively, traditional setting.
Popular casual spot famed for Roman-style pizzas and fried starters. Bustling atmosphere and a long-standing local reputation.
Moderate for Europe: stays in central Rome are pricey, but transit is cheap and meals range from affordable pizza to costly tourist-area dining.
Service may be included via coperto or servizio. Round up or leave 5-10% at restaurants if service is good; round up in taxis; small change is fine at cafés.
Official public transport app
Roma Termini -> Piazza Di Spagna, Rome
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Rome.
Find answers to the most common questions about traveling from Pisa Centrale to Rome by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Rome, this guide helps you travel smarter and with confidence.

Most Pisa Centrale to Rome trains use the Pisa Centrale to Roma Termini station pair, with some services arriving at Roma Tiburtina. Use this guide to compare Pisa Centrale and Rome train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
Pisa Centrale has practical services for this route, including Wifi, Lockers, Parking, Dining, Taxis, Accessibility, WC, Hotel, Ticket Office, Bike Parking, Bike Rental, and Information Desk.
Food options include: McDonald's, Panetteria Binario 1
There is free Wi-Fi available at the McDonald's.
The ticket office is open Mon - Sun: 06:00 - 20:30. Information desks are located just outside the station on Piazza Vittorio Emanuele II.
Luggage storage is there is a luggage storage office near the end of Platform 1.
Available at Pisa Centrale: Parking, Taxis, WC.
Available at Pisa Centrale: Bike Parking, Bike Rental.
Accessibility facilities are available at Pisa Centrale: Accessible facilities including barrier-free restrooms, elevators, ramps, and disabled parking. Sala Blu mobility assistance available from 07:45 to 22:30 with advanced one-hour notice.
Nearby hotels include Hotel NH Pisa, Hotel La Pace, Hotel Maria.
Roma Termini is 1 km from Rome city centre. Public transport options include:
Roma Termini has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Ticket Office, Bike Parking, Car Rental, and Information Desk.
Food options include: Acafe, Moka Café, Roadhouse Grill, McDonald's, Gusto, Chef Express, Coop Minimarket, Mercato Centrale
Free WiFi in the station. ATMs are there are ATMs in various locations around the station.
The ticket office is open Mon - Sun: 06:30 - 22:00. Information desks are located near Platform 24.
Luggage storage is provided by KiPoint and located on Platform 24. Open every day from 06:00 to 23:00.
Available at Roma Termini: Parking, Taxis, WC.
Available at Roma Termini: Bike Parking, Car Rental.
Accessibility facilities are available at Roma Termini: The Sala Blu, Trenitalia's office of assistance for disabled travelers, is located next to Platform 1.
Nearby hotels include Archi di Roma Guest House, Gemma di Roma, The Liberty Boutique Hotel.
Roma Tiburtina is 4 km from Rome city centre. Public transport options include:
Roma Tiburtina has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Ticket Office, Bike Parking, Car Rental, and Information Desk.
Food options include: Rock n’ Coffee Roma, Arabian Kebab, Ingredienti, McDonald’s, Numb's Bakery Café
Free, limited Wi-Fi available in the station for 15 minutes. ATMs are located on the ground floor level.
The ticket office is open Mon - Sun: 06:35 - 20:20. Information desks are located inside the main terminal. .
Luggage storage is luggage lockers are located in the station lobby.
Available at Roma Tiburtina: Parking, Taxis, WC.
Available at Roma Tiburtina: Bike Parking, Car Rental.
Accessibility facilities are available at Roma Tiburtina: Accessible facilities include elevators and escalators.
Nearby hotels include B&B Rome Tiburtina, B&B Alba Domus Roma, Hotel delle Province.
Roma Ostiense is 2 km from Rome city centre. Public transport options include:
Roma Ostiense has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Car Rental, Information Desk, and Luggage Carts.
Food options include: Ramen Bar Akira, Eataly Roma
Free. ATMs are available in the train station.
Ticket office support is available at Roma Ostiense. Information desks are located in the main hall.
Luggage storage is available at Roma Ostiense. Lost and found is available at the station.
Available at Roma Ostiense: Parking, Taxis, WC.
Available at Roma Ostiense: Bike Parking, Car Rental.
Accessibility facilities are available at Roma Ostiense: Elevators, ramps, restrooms.
Nearby hotels include Hotel Abitart, Hotel San Anselmo, Hotel Villa San Pio.