The cheapest and fastest trains from Pisa Centrale to Rome Ostiense
Cheapest price
$32
Average price
$64
Fastest journey
2 h 44 m
Average duration
3 h 1 m
Trains per day
35
Distance
266 km
The best way to find a cheap train ticket from Pisa Centrale to Rome Ostiense is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Pisa Centrale to Rome Ostiense will cost around $64 if you buy it on the day, but the cheapest tickets can be found for only $32.
Of the 35 trains that leave Pisa Centrale for Rome Ostiense on Tue, Feb 24, 11 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Tue, Feb 24 the direct trains cover the 266 km distance in an average of 3 h 1 m but if you time it right, some trains will get you there in just 2 h 44 m .
On Tue, Feb 24 the slowest trains will take 3 h 12 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
ETRUSCHI LINE 4137
ETRUSCHI LINE 4129 · Treno 4129 effettuato con bus FI001 · Regionale 12663
ETRUSCHI LINE 4131
ETRUSCHI LINE 4139
ETRUSCHI LINE 4135
FRECCIARGENTO 8551+
Regionale 20461
Intercity 511
FRECCIARGENTO 8591+
Regionale 12554
Intercity 505
InterCityNotte 795Travel Information
Compare train and bus for Pisa Centrale to Rome Ostiense
Omio recommends booking the train as it is the most popular option from Pisa Centrale to Rome Ostiense among Omio's users. If you are prioritising price take the bus with prices starting from $16. For those with little time consider booking a train which can get you there in 3h 12m. The ticket price range depends on the travel mode: a bus costs an average of $16, and a train costs an average of $16.
Distance: 165 miles (266 km)
Compare train with
Most popular Train | Bus |
|---|---|
$28 Average price | $20 Average price Cheapest |
3h 42m Average total duration Fastest 3h 12m Onboard + 30m Additional time* | 5h 0m Average total duration 4h 30m Onboard + 30m Additional time* |
![]() Most popular train company | ![]() Most popular bus company |
Direct Options | Direct Options |
Live departures
Pisa Centrale to Rome Ostiense train times
The table below shows live departures for Pisa Centrale to Rome Ostiense trains for tomorrow, Tuesday, February 24. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
InterCityNotte 899 | 1:21 AM Pisa Centrale | 3h22 | 4:43 AM Rome Ostiense | 0 transfersDirect | |
Regionale 18250+ FRECCIAROSSA 1000 9503+ Regionale 12506 | 3:15 AM Pisa Centrale | 4h07 | 7:22 AM Rome Ostiense | 2 transfers | |
Regionale 18250+ Intercity 581+ Regionale 12508 | 3:15 AM Pisa Centrale | 4h37 | 7:52 AM Rome Ostiense | 2 transfers | |
Regionale 18254+ FRECCIAROSSA 9505+ Regionale 23254 | 4:39 AM Pisa Centrale | 3h42 | 8:21 AM Rome Ostiense | 2 transfers | |
ETRUSCHI LINE 4125 | 4:45 AM Pisa Centrale | 3h52 | 8:37 AM Rome Ostiense | 0 transfersDirect | |
Tuscany Line 18260+ FRECCIAROSSA 9401+ Regionale 20445 | 5:29 AM Pisa Centrale | 3h15 | 8:44 AM Rome Ostiense | 2 transfers | |
Intercity 501 | 5:47 AM Pisa Centrale | 3h28 | 9:15 AM Rome Ostiense | 0 transfersDirect | |
FRECCIABIANCA 8601+ ETRUSCHI LINE 4130 | 6:07 AM Pisa Centrale | 3h15 | 9:22 AM Rome Ostiense | 1 transfer | |
ETRUSCHI LINE 4129 · Treno 4129 effettuato con bus FI001 · Regionale 12663 | 6:45 AM Pisa Centrale | 6h21 | 1:06 PM Rome Ostiense | 2 transfers | |
ETRUSCHI LINE 18270+ FRECCIAROSSA 8513+ Regionale 23258 | 6:54 AM Pisa Centrale | 3h27 | 10:21 AM Rome Ostiense | 2 transfers | |
ETRUSCHI LINE 4016+ FRECCIAROSSA 9405+ Regionale 12520 | 7:32 AM Pisa Centrale | 3h21 | 10:53 AM Rome Ostiense | 2 transfers | |
ETRUSCHI LINE 4016+ Intercity 583+ Regionale 20483 | 7:32 AM Pisa Centrale | 5h27 | 12:59 PM Rome Ostiense | 2 transfers | |
FRECCIARGENTO 8551+ Regionale 20461 | 8:15 AM Pisa Centrale | 2h44 | 10:59 AM Rome Ostiense | 1 transfer | |
TUSCANY LINE 4020+ FRECCIAROSSA 1000 9391+ Regionale 20390 | 8:32 AM Pisa Centrale | 3h19 | 11:51 AM Rome Ostiense | 2 transfers | |
TUSCANY LINE 4026+ FRECCIAROSSA 1000 9411+ Regionale 12524 | 9:32 AM Pisa Centrale | 3h20 | 12:52 PM Rome Ostiense | 2 transfers | |
Intercity 505 | 10:11 AM Pisa Centrale | 3h09 | 1:20 PM Rome Ostiense | 0 transfersDirect | |
TUSCANY LINE 4030+ FRECCIAROSSA 1000 9413+ Regionale 12564 | 10:30 AM Pisa Centrale | 3h22 | 1:52 PM Rome Ostiense | 2 transfers | |
ETRUSCHI LINE 4131 | 10:45 AM Pisa Centrale | 3h51 | 2:36 PM Rome Ostiense | 0 transfersDirect | |
TUSCANY LINE 4032+ FRECCIAROSSA 1000 9415+ Regionale 20497 | 11:32 AM Pisa Centrale | 3h12 | 2:44 PM Rome Ostiense | 2 transfers | |
Regionale Veloce 4036+ FRECCIAROSSA 1000 8419+ Regionale 12534 | 12:32 PM Pisa Centrale | 3h20 | 3:52 PM Rome Ostiense | 2 transfers | |
ETRUSCHI LINE 4133 | 12:43 PM Pisa Centrale | 3h53 | 4:36 PM Rome Ostiense | 0 transfersDirect | |
FRECCIABIANCA 8613+ Regionale 4502 | 1:07 PM Pisa Centrale | 3h15 | 4:22 PM Rome Ostiense | 1 transfer | |
Tuscany Line 4038+ FRECCIAROSSA 9421+ Regionale 20523 | 1:32 PM Pisa Centrale | 3h12 | 4:44 PM Rome Ostiense | 2 transfers | |
Intercity 511 | 1:53 PM Pisa Centrale | 2h59 | 4:52 PM Rome Ostiense | 0 transfersDirect | |
Regionale Veloce 4042+ FRECCIAROSSA 1000 9425+ Regionale 12666 | 2:32 PM Pisa Centrale | 3h20 | 5:52 PM Rome Ostiense | 2 transfers | |
ETRUSCHI LINE 4135 | 2:45 PM Pisa Centrale | 3h54 | 6:39 PM Rome Ostiense | 0 transfersDirect | |
Tuscany Line 4044+ FRECCIAROSSA 1000 9427+ Regionale 12546 | 3:32 PM Pisa Centrale | 3h21 | 6:53 PM Rome Ostiense | 2 transfers | |
FRECCIABIANCA 8619+ Regionale 12561 | 4:07 PM Pisa Centrale | 3h29 | 7:36 PM Rome Ostiense | 1 transfer | |
Regionale Veloce 4046+ FRECCIAROSSA 8525+ Regionale 12548 | 4:09 PM Pisa Centrale | 3h28 | 7:37 PM Rome Ostiense | 2 transfers | |
ETRUSCHI LINE 4048+ FRECCIAROSSA 9325+ Regionale 23292 | 4:32 PM Pisa Centrale | 3h18 | 7:50 PM Rome Ostiense | 2 transfers | |
ETRUSCHI LINE 4137 | 4:45 PM Pisa Centrale | 3h51 | 8:36 PM Rome Ostiense | 0 transfersDirect | |
Tuscany Line 4052+ FRECCIAROSSA 1000 9433+ Regionale 12586 | 5:32 PM Pisa Centrale | 3h20 | 8:52 PM Rome Ostiense | 2 transfers | |
ETRUSCHI LINE 4139 | 6:45 PM Pisa Centrale | 3h51 | 10:36 PM Rome Ostiense | 0 transfersDirect | |
InterCityNotte 795 | 7:11 PM Pisa Centrale | 3h12 | 10:23 PM Rome Ostiense | 0 transfersDirect | |
FRECCIARGENTO 8591+ Regionale 12554 | 7:38 PM Pisa Centrale | 2h59 | 10:37 PM Rome Ostiense | 1 transfer | |
Find all the dates and times for this journey
Compare prices and tickets Pisa Centrale to Rome Ostiense by train or bus
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Feb 24
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Mar 01
Mar 02
Journey information
Overview: Train from Pisa Centrale to Rome Ostiense
Trains from Pisa Centrale to Rome Ostiense run on average 29 times per day, taking around 3h 12m. Cheap train tickets for this journey start at $16 (€13) but you can travel from only $16 (€12) by bus.
There are 11 trains per day. The earliest train runs at 01:21, the last at 16:07. The fastest train covers the 165 miles (266 km) distance in 3h 9m.
Distance 165 miles (266 km) |
Average train duration 3h 12m |
Cheapest ticket price $16 (€13) |
Trains per day 29 |
Direct trains 11 |
Fastest train 3h 9m |
First train 01:21 |
Last train 16:07 |
Train companies: Regionale, Intercity Notte, Intercity, Frecciabianca, Frecciargento, Frecciarossa from Pisa Centrale to Rome Ostiense trainsRegionale, Intercity Notte, Intercity, Frecciabianca, Frecciargento, Frecciarossa trains will get you between Pisa Centrale and Rome Ostiense from $16 (€12). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Regionale
Intercity Notte
Intercity
Frecciabianca
Frecciargento
Frecciarossa
FAQs: Trains from Pisa Centrale to Rome Ostiense
Find answers to the most common questions about traveling from Pisa Centrale to Rome Ostiense by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Rome Ostiense, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Pisa Centrale to Rome Ostiense
- Mon - Sun: 06:00 - 20:30
- There is free Wi-Fi available at the McDonald's.
- There is a luggage storage office near the end of Platform 1.
- McDonald's
- Panetteria Binario 1
- Accessible facilities including barrier-free restrooms, elevators, ramps, and disabled parking. Sala Blu mobility assistance available from 07:45 to 22:30 with advanced one-hour notice.
- Hotel NH Pisa
- Hotel La Pace
- Hotel Maria
- Mon - Sun: 06:00 - 20:30
- Located just outside the station on Piazza Vittorio Emanuele II.
- Bus lines: 1
- Train lines: Pisamover (S2), FA, FB, IC, ICN, RV, R, EN
- 6:00 AM - 10:00 PM Monday - Sunday
- Free
- Parking is available near the station with both short-term and long-term options.
- Ramen Bar Akira
- Eataly Roma
- Outside the main entrance.
- Elevators, ramps, restrooms.
- €1
- Hotel Abitart
- Hotel San Anselmo
- Hotel Villa San Pio
- Located in the main hall
- Avis
- Europcar
- Located in the main hall
- Free
- Hall 1: main entrance, platforms 1-5 for regional and intercity trains
- Hall 2: platforms 6-11 for metropolitan services
- Metro: Line B
- Bus: Several lines available
- Tram: Line 3
Most popular train connections from Pisa Centrale
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