The cheapest and fastest trains from Pisa Centrale to Rome Ostiense
Cheapest price
$31
Average price
$31
Fastest journey
3 h 52 m
Average duration
3 h 57 m
Trains per day
3
Distance
266 km
The best way to find a cheap train ticket from Pisa Centrale to Rome Ostiense is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Pisa Centrale to Rome Ostiense will cost around $31 if you buy it on the day, but the cheapest tickets can be found for only $31.
Of the 3 trains that leave Pisa Centrale for Rome Ostiense on Sun, Nov 09, 3 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sun, Nov 09 the direct trains cover the 266 km distance in an average of 3 h 57 m but if you time it right, some trains will get you there in just 3 h 52 m .
On Sun, Nov 09 the slowest trains will take 4 h 4 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.






Travel Information
Compare train and bus for Pisa Centrale to Rome Ostiense
Omio recommends booking the train as it is the most popular option from Pisa Centrale to Rome Ostiense among Omio's users. If you are prioritising price take the bus with prices starting from €12. For those with little time consider booking a train which can get you there in 3h 12m. The ticket price range depends on the travel mode: a bus costs an average of €12, and a train costs an average of €15.
Distance: 165 miles (266 km)
Compare train with
Most popular Train | Bus |
|---|---|
€24 Average price | €17 Average price Cheapest |
3h 42m Average total duration Fastest 3h 12m Onboard + 30m Additional time* | 5h 0m Average total duration 4h 30m Onboard + 30m Additional time* |
![]() Most popular train company | ![]() Most popular bus company |
Direct Options | Direct Options |
Live departures
Pisa Centrale to Rome Ostiense train times
The table below shows live departures for Pisa Centrale to Rome Ostiense trains for today, Saturday, November 8. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
Regionale Veloce 4129 | 6:35 AM Pisa Centrale | 4h01 | 10:36 AM Rome Ostiense | 0 transfersDirect | |
Tuscany Line 19155 · TUSCANY LINE 18507+ 8905+ Regionale Veloce 4153 | 6:50 AM Pisa Centrale | 5h33 | 12:23 PM Rome Ostiense | 4 transfers | |
Tuscany Line 19155 · TUSCANY LINE 18507+ 8911+ Regionale 4107 | 6:50 AM Pisa Centrale | 12h32 | 7:22 PM Rome Ostiense | 4 transfers | |
Tuscany Line 19155 · TUSCANY LINE 18507+ 8905+ Regionale 4107 | 6:50 AM Pisa Centrale | 12h32 | 7:22 PM Rome Ostiense | 4 transfers | |
TUSCANY LINE 18489+ 9923+ Regionale 4107 · Regionale 4140 | 7:50 AM Pisa Centrale | 11h32 | 7:22 PM Rome Ostiense | 3 transfers | |
TUSCANY LINE 18489+ 8913+ Regionale 4107 · Regionale 4140 | 7:50 AM Pisa Centrale | 11h32 | 7:22 PM Rome Ostiense | 3 transfers | |
TUSCANY LINE 18489+ 8911+ Regionale 4107 · Regionale 4140 | 7:50 AM Pisa Centrale | 11h32 | 7:22 PM Rome Ostiense | 3 transfers | |
FRECCIABIANCA 8605+ Regionale 34585 | 8:07 AM Pisa Centrale | 3h31 | 11:38 AM Rome Ostiense | 1 transfer | |
TUSCANY LINE 18563 · TUSCANY LINE 18511+ 8911+ Regionale 4107 | 8:50 AM Pisa Centrale | 10h32 | 7:22 PM Rome Ostiense | 4 transfers | |
TUSCANY LINE 18563 · TUSCANY LINE 18511+ 8919+ Regionale 4107 | 8:50 AM Pisa Centrale | 10h32 | 7:22 PM Rome Ostiense | 4 transfers | |
TUSCANY LINE 18563 · TUSCANY LINE 18511+ 9947+ Regionale 4107 | 8:50 AM Pisa Centrale | 10h32 | 7:22 PM Rome Ostiense | 4 transfers | |
Intercity 505 | 10:13 AM Pisa Centrale | 3h19 | 1:32 PM Rome Ostiense | 0 transfersDirect | |
Regionale Veloce 4131 | 10:35 AM Pisa Centrale | 4h01 | 2:36 PM Rome Ostiense | 0 transfersDirect | |
Intercity 1589 | 10:57 AM Pisa Centrale | 4h25 | 3:22 PM Rome Ostiense | 0 transfersDirect | |
BUS L589C+ TUSCANY LINE 18515+ 9947+ Regionale 4107 | 11:10 AM Pisa Centrale | 8h12 | 7:22 PM Rome Ostiense | 4 transfers | |
BUS L589C+ TUSCANY LINE 18515+ 8913+ Regionale 4107 | 11:10 AM Pisa Centrale | 8h12 | 7:22 PM Rome Ostiense | 4 transfers | |
BUS L589C+ TUSCANY LINE 18515+ 8919+ Regionale 4107 | 11:10 AM Pisa Centrale | 8h12 | 7:22 PM Rome Ostiense | 4 transfers | |
Tuscany Line 18491+ 8919+ Regionale 4107 · Regionale 4140 | 11:50 AM Pisa Centrale | 7h32 | 7:22 PM Rome Ostiense | 3 transfers | |
Tuscany Line 18491+ 9947+ Regionale 4107 · Regionale 4140 | 11:50 AM Pisa Centrale | 7h32 | 7:22 PM Rome Ostiense | 3 transfers | |
Tuscany Line 18491+ 9939+ Regionale 4107 · Regionale 4140 | 11:50 AM Pisa Centrale | 7h32 | 7:22 PM Rome Ostiense | 3 transfers | |
Regionale Veloce 4133 | 12:33 PM Pisa Centrale | 4h03 | 4:36 PM Rome Ostiense | 0 transfersDirect | |
Regionale 19165 · Tuscany Line 18519+ 8919+ Regionale 4107 | 12:43 PM Pisa Centrale | 6h39 | 7:22 PM Rome Ostiense | 4 transfers | |
Regionale 19165 · Tuscany Line 18519+ 9947+ Regionale 4107 | 12:43 PM Pisa Centrale | 6h39 | 7:22 PM Rome Ostiense | 4 transfers | |
Regionale 19165 · Tuscany Line 18519+ 9947+ Regionale Veloce 4735 | 12:43 PM Pisa Centrale | 7h39 | 8:22 PM Rome Ostiense | 4 transfers | |
FRECCIABIANCA 8613+ Regionale Veloce 4133 | 1:07 PM Pisa Centrale | 3h29 | 4:36 PM Rome Ostiense | 1 transfer | |
Tuscany Line 18493+ 9947+ Regionale Veloce 4735 · Regionale 4506 | 1:50 PM Pisa Centrale | 6h32 | 8:22 PM Rome Ostiense | 3 transfers | |
Tuscany Line 18493+ 9947+ Regionale 4107 · Regionale 4140 | 1:50 PM Pisa Centrale | 5h32 | 7:22 PM Rome Ostiense | 3 transfers | |
Tuscany Line 18493+ 9951+ Regionale Veloce 4735 · Regionale 4506 | 1:50 PM Pisa Centrale | 6h32 | 8:22 PM Rome Ostiense | 3 transfers | |
Intercity 511 | 1:52 PM Pisa Centrale | 3h00 | 4:52 PM Rome Ostiense | 0 transfersDirect | |
Regionale Veloce 4135 | 2:37 PM Pisa Centrale | 3h59 | 6:36 PM Rome Ostiense | 0 transfersDirect | |
Tuscany Line 18583 · Tuscany Line 18525+ 9951+ Regionale Veloce 4735 | 2:50 PM Pisa Centrale | 5h32 | 8:22 PM Rome Ostiense | 4 transfers | |
Tuscany Line 18497+ 9951+ Regionale Veloce 4735 · Regionale 4506 | 3:19 PM Pisa Centrale | 5h03 | 8:22 PM Rome Ostiense | 3 transfers | |
Intercity 597 | 3:37 PM Pisa Centrale | 3h03 | 6:40 PM Rome Ostiense | 0 transfersDirect | |
FRECCIABIANCA 8619+ Regionale 12550 | On time 4:07 PM Pisa Centrale | 3h45 | 7:52 PM Rome Ostiense | 1 transfer | |
Regionale Veloce 4137 | 4:35 PM Pisa Centrale | 4h01 | 8:36 PM Rome Ostiense | 0 transfersDirect | |
FRECCIAROSSA 8623+ Regionale 12565 | 6:11 PM Pisa Centrale | 3h40 | 9:51 PM Rome Ostiense | 1 transfer | |
ETRUSCHI LINE 4139 | 6:35 PM Pisa Centrale | 4h02 | 10:37 PM Rome Ostiense | 0 transfersDirect | |
InterCityNotte 795 | 7:11 PM Pisa Centrale | 3h12 | 10:23 PM Rome Ostiense | 0 transfersDirect | |
| Sunday, November 9 | |||||
![]() | 5:35 AM Pisa Centrale | 4h04 | 9:39 AM Rome Ostiense | 0 transfersDirect | |
![]() | 5:45 AM Pisa Centrale | 3h54 | 9:39 AM Rome Ostiense | 0 transfersDirect | |
Find all the dates and times for this journey
Compare prices and tickets Pisa Centrale to Rome Ostiense by train or bus
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Nov 09
Nov 10
Nov 11
Nov 12
Nov 13
Nov 14
Nov 15
Journey information
Overview: Train from Pisa Centrale to Rome Ostiense
Trains from Pisa Centrale to Rome Ostiense run on average 30 times per day, taking around 3h 12m. Cheap train tickets for this journey start at $18 (€15) but you can travel from only $15 (€12) by bus.
There are 11 trains per day. The earliest train runs at 03:45, the last at 18:11. The fastest train covers the 165 miles (266 km) distance in 3h 12m.
Distance 165 miles (266 km) |
Average train duration 3h 12m |
Cheapest ticket price $18 (€15) |
Trains per day 30 |
Direct trains 11 |
Fastest train 3h 12m |
First train 03:45 |
Last train 18:11 |
Train companies: Regionale, Intercity Notte, Intercity, Frecciabianca, Frecciargento, Frecciarossa from Pisa Centrale to Rome Ostiense trainsRegionale, Intercity Notte, Intercity, Frecciabianca, Frecciargento, Frecciarossa trains will get you between Pisa Centrale and Rome Ostiense from $15 (€12). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Regionale
Intercity Notte
Intercity
Frecciabianca
Frecciargento
Frecciarossa
FAQs: Trains from Pisa Centrale to Rome Ostiense
Find answers to the most common questions about traveling from Pisa Centrale to Rome Ostiense by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Rome Ostiense, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Pisa Centrale to Rome Ostiense
- Mon - Sun: 06:00 - 20:30
- There is free Wi-Fi available at the McDonald's.
- There is a luggage storage office near the end of Platform 1.
- McDonald's
- Panetteria Binario 1
- Accessible facilities including barrier-free restrooms, elevators, ramps, and disabled parking. Sala Blu mobility assistance available from 07:45 to 22:30 with advanced one-hour notice.
- Hotel NH Pisa
- Hotel La Pace
- Hotel Maria
- Mon - Sun: 06:00 - 20:30
- Located just outside the station on Piazza Vittorio Emanuele II.
- Bus lines: 1
- Train lines: Pisamover (S2), FA, FB, IC, ICN, RV, R, EN
- 6:00 AM - 10:00 PM Monday - Sunday
- Free
- Parking is available near the station with both short-term and long-term options.
- Ramen Bar Akira
- Eataly Roma
- Outside the main entrance.
- Elevators, ramps, restrooms.
- €1
- Hotel Abitart
- Hotel San Anselmo
- Hotel Villa San Pio
- Located in the main hall
- Avis
- Europcar
- Located in the main hall
- Free
- Hall 1: main entrance, platforms 1-5 for regional and intercity trains
- Hall 2: platforms 6-11 for metropolitan services
- Metro: Line B
- Bus: Several lines available
- Tram: Line 3
Most popular train connections from Pisa Centrale
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