- Must visit
Galleria degli Uffizi
World-famous Renaissance gallery with masterpieces by Botticelli, Leonardo, Michelangelo, and Caravaggio. Timed entry is strongly recommended due to high demand.
We are not able to find a train between these two places.
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Omio recommends booking the train as it is the most popular option from Pisa Centrale to Florence Santa Maria Novella among Omio's users. If you are prioritising price take the train with prices starting from $11. For those with little time consider booking a bus which can get you there in 1h 12m. The ticket price range depends on the travel mode: a train costs an average of $11, and a bus costs an average of $10.
Distance: 42 miles (69 km)
Most popular Train | Bus | Driving |
|---|---|---|
$12 Average price Cheapest | $14 Average price | $17 Average price (fuel + tolls) |
2h 25m Average total duration 1h 55m Onboard + 30m Additional time* | 1h 42m Average total duration Fastest 1h 12m Onboard + 30m Additional time* | 1h 10m Average total duration (door-to-door) |
![]() Most popular train company | ![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Pisa Centrale to Florence Santa Maria Novella:
A train is $3 (€2) less than a bus for this route with tickets for a bus from Pisa Centrale to Florence Santa Maria Novella costing on average $14 (€12).
Other travel options to Florence Santa Maria Novella take longer:
Train takes on average 1h 55m.
Tickets start at around {cheapestPrice} compared to roughly {drivingPriceInCents} in fuel and tolls — a saving of about {savingsAmount}. The journey takes {durationInMinutes} versus {drivingDurationInMinutes} by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Direct services run with Regionale.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
The table below shows live departures for Pisa Centrale to Florence Santa Maria Novella trains for tomorrow, Saturday, July 11. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
Regionale 18250 | 4:15 AM Pisa Centrale | 1h13 | 5:28 AM Florence Santa Maria Novella | 0 transfersDirect | |
Regionale 18252 | 5:19 AM Pisa Centrale | 1h20 | 6:39 AM Florence Santa Maria Novella | 0 transfersDirect | |
Regionale 18254 | 5:39 AM Pisa Centrale | 1h14 | 6:53 AM Florence Santa Maria Novella | 0 transfersDirect | |
Regionale 18391 | 5:53 AM Pisa Centrale | 1h21 | 7:14 AM Florence Santa Maria Novella | 0 transfersDirect | |
Regionale 18260 | 6:29 AM Pisa Centrale | 0h59 | 7:28 AM Florence Santa Maria Novella | 0 transfersDirect | |
Regionale 18264 | 6:54 AM Pisa Centrale | 1h15 | 8:09 AM Florence Santa Maria Novella | 0 transfersDirect | |
Regionale 18266 | 6:58 AM Pisa Centrale | 1h21 | 8:19 AM Florence Santa Maria Novella | 0 transfersDirect | |
Regionale Veloce 4014 | 7:38 AM Pisa Centrale | 1h00 | 8:38 AM Florence Santa Maria Novella | 0 transfersDirect | |
Regionale 18425 | 7:44 AM Pisa Centrale | 1h04 | 8:48 AM Florence Santa Maria Novella | 0 transfersDirect | |
Regionale 18268 | 7:54 AM Pisa Centrale | 1h14 | 9:08 AM Florence Santa Maria Novella | 0 transfersDirect | |
Regionale 18272 | 8:03 AM Pisa Centrale | 1h20 | 9:23 AM Florence Santa Maria Novella | 0 transfersDirect | |
Regionale Veloce 4016 | 8:32 AM Pisa Centrale | 1h01 | 9:33 AM Florence Santa Maria Novella | 0 transfersDirect | |
Regionale 34095 | 8:50 AM Pisa Centrale | 2h34 | 11:24 AM Florence Santa Maria Novella | 0 transfersDirect | |
Regionale Veloce 4018 | 9:09 AM Pisa Centrale | 0h52 | 10:01 AM Florence Santa Maria Novella | 0 transfersDirect | |
Regionale Veloce 4020 | 9:32 AM Pisa Centrale | 1h01 | 10:33 AM Florence Santa Maria Novella | 0 transfersDirect | |
Regionale 18282 | 9:54 AM Pisa Centrale | 1h14 | 11:08 AM Florence Santa Maria Novella | 0 transfersDirect | |
Regionale 18286 | 10:01 AM Pisa Centrale | 1h22 | 11:23 AM Florence Santa Maria Novella | 0 transfersDirect | |
Regionale Veloce 4026 | 10:32 AM Pisa Centrale | 1h01 | 11:33 AM Florence Santa Maria Novella | 0 transfersDirect | |
Regionale 18411 | 10:54 AM Pisa Centrale | 1h14 | 12:08 PM Florence Santa Maria Novella | 0 transfersDirect | |
Regionale 4028 | 11:09 AM Pisa Centrale | 0h52 | 12:01 PM Florence Santa Maria Novella | 0 transfersDirect | |
Regionale Veloce 4030 | 11:30 AM Pisa Centrale | 1h03 | 12:33 PM Florence Santa Maria Novella | 0 transfersDirect | |
Regionale 18288 | 11:54 AM Pisa Centrale | 1h14 | 1:08 PM Florence Santa Maria Novella | 0 transfersDirect | |
Regionale 18290 | 12:01 PM Pisa Centrale | 1h22 | 1:23 PM Florence Santa Maria Novella | 0 transfersDirect | |
Regionale Veloce 4032 | 12:32 PM Pisa Centrale | 1h01 | 1:33 PM Florence Santa Maria Novella | 0 transfersDirect | |
Regionale 18296 | 12:54 PM Pisa Centrale | 1h13 | 2:07 PM Florence Santa Maria Novella | 0 transfersDirect | |
Regionale Veloce 4034 | 1:09 PM Pisa Centrale | 0h52 | 2:01 PM Florence Santa Maria Novella | 0 transfersDirect | |
Regionale Veloce 19498 | 1:32 PM Pisa Centrale | 1h01 | 2:33 PM Florence Santa Maria Novella | 0 transfersDirect | |
Regionale 18413 | 1:54 PM Pisa Centrale | 1h14 | 3:08 PM Florence Santa Maria Novella | 0 transfersDirect | |
Regionale 18304 | 2:01 PM Pisa Centrale | 1h24 | 3:25 PM Florence Santa Maria Novella | 0 transfersDirect | |
Regionale Veloce 4038 | 2:32 PM Pisa Centrale | 1h01 | 3:33 PM Florence Santa Maria Novella | 0 transfersDirect | |
Regionale 18393 | 2:54 PM Pisa Centrale | 1h14 | 4:08 PM Florence Santa Maria Novella | 0 transfersDirect | |
Regionale 18306 | 3:09 PM Pisa Centrale | 0h52 | 4:01 PM Florence Santa Maria Novella | 0 transfersDirect | |
Regionale Veloce 4042 | 3:32 PM Pisa Centrale | 1h01 | 4:33 PM Florence Santa Maria Novella | 0 transfersDirect | |
Regionale 18415 | 3:54 PM Pisa Centrale | 1h14 | 5:08 PM Florence Santa Maria Novella | 0 transfersDirect | |
Regionale 18308 | 4:01 PM Pisa Centrale | 1h24 | 5:25 PM Florence Santa Maria Novella | 0 transfersDirect | |
Regionale Veloce 4044 | 4:32 PM Pisa Centrale | 1h01 | 5:33 PM Florence Santa Maria Novella | 0 transfersDirect | |
Regionale 18399 | 4:54 PM Pisa Centrale | 1h14 | 6:08 PM Florence Santa Maria Novella | 0 transfersDirect | |
Regionale Veloce 4046 | 5:09 PM Pisa Centrale | 0h52 | 6:01 PM Florence Santa Maria Novella | 0 transfersDirect | |
Regionale Veloce 4048 | 5:32 PM Pisa Centrale | 1h01 | 6:33 PM Florence Santa Maria Novella | 0 transfersDirect | |
Regionale 18401 | 5:54 PM Pisa Centrale | 1h14 | 7:08 PM Florence Santa Maria Novella | 0 transfersDirect | |
Regionale Veloce 4052 | 6:32 PM Pisa Centrale | 1h01 | 7:33 PM Florence Santa Maria Novella | 0 transfersDirect | |
Regionale 18403 | 6:54 PM Pisa Centrale | 1h14 | 8:08 PM Florence Santa Maria Novella | 0 transfersDirect | |
Regionale Veloce 4056 | 7:09 PM Pisa Centrale | 0h52 | 8:01 PM Florence Santa Maria Novella | 0 transfersDirect | |
Regionale Veloce 4058 | 7:32 PM Pisa Centrale | 1h01 | 8:33 PM Florence Santa Maria Novella | 0 transfersDirect | |
Regionale 18423 | 7:54 PM Pisa Centrale | 1h14 | 9:08 PM Florence Santa Maria Novella | 0 transfersDirect | |
Regionale Veloce 4060 | 8:32 PM Pisa Centrale | 1h07 | 9:39 PM Florence Santa Maria Novella | 0 transfersDirect | |
FRECCIARGENTO 8591+ Regionale Veloce 93648 | 8:38 PM Pisa Centrale | 1h12 | 9:50 PM Florence Santa Maria Novella | 1 transfer | |
Regionale 18407 · Regionale 18242 | 8:42 PM Pisa Centrale | 1h10 | 9:52 PM Florence Santa Maria Novella | 1 transfer | |
Regionale 18407 | 8:42 PM Pisa Centrale | 1h15 | 9:57 PM Florence Santa Maria Novella | 0 transfersDirect | |
Regionale 19486 | 8:56 PM Pisa Centrale | 1h12 | 10:08 PM Florence Santa Maria Novella | 0 transfersDirect | |
Regionale 18322 | 9:01 PM Pisa Centrale | 1h25 | 10:26 PM Florence Santa Maria Novella | 0 transfersDirect | |
Regionale 18324 | 9:32 PM Pisa Centrale | 1h01 | 10:33 PM Florence Santa Maria Novella | 0 transfersDirect | |
Regionale 18330 | 10:30 PM Pisa Centrale | 1h20 | 11:50 PM Florence Santa Maria Novella | 0 transfersDirect | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Trains from Pisa Centrale to Florence Santa Maria Novella run on average 43 times per day, taking around 1h 55m. Cheap train tickets for this journey start at $11 (€9) but you can travel from only $10 (€8) by bus.
There are 40 trains per day. The earliest train runs at 03:47, the last at 21:30. The fastest train covers the 42 miles (69 km) distance in 52m.
Distance 42 miles (69 km) |
Average train duration 1h 55m |
Cheapest ticket price $11 (€9) |
Trains per day 43 |
Direct trains 40 |
Fastest train 52m |
First train 3:47 AM |
Last train 9:30 PM |
Cheapest Month Jan |
Cheapest Day Fri |
High Season Apr - Jun |
Low Season Jan - Mar |
Busiest Day Mon |
Least Busy Day Wed |
Discover the best of Firenze Santa Maria Novella — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Firenze Santa Maria Novella trip today.
World-famous Renaissance gallery with masterpieces by Botticelli, Leonardo, Michelangelo, and Caravaggio. Timed entry is strongly recommended due to high demand.
Best known for Michelangelo's David, this compact museum also holds important Florentine paintings and sculpture. Advance booking is commonly recommended.
Large palace museum complex with royal apartments, art collections, and access to the Boboli Gardens. A major stop for Medici history and grand interiors.
The ceremonial heart of Florence, packed with the cathedral, baptistery, and bell tower. Essential for first-time visitors and classic city views.
Historic square filled with civic symbolism, monumental sculpture, and constant activity. One of Florence's most recognizable public spaces.
The best-known panoramic terrace over Florence, especially popular at sunset and widely featured on social media. Excellent for skyline photography.
Thick-cut T-bone steak from Chianina beef, grilled rare over coals. It is the signature Florentine dish and a classic of Tuscan cooking.
Hearty Tuscan soup of bread, cannellini beans, kale, and vegetables, traditionally reheated the next day. A beloved local peasant dish.
Rustic tomato and bread soup with garlic, olive oil, and basil. It is a comforting Florentine staple made from simple Tuscan ingredients.
Celebrated fine-dining destination with refined Italian cuisine and an exceptional wine program. Ideal for a special high-end meal in Florence.
Historic, no-frills trattoria near the central market, known for Bistecca Alla Fiorentina, hearty Tuscan classics, and a lively local atmosphere.
Popular long-running trattoria near Mercato Centrale with a broad Tuscan menu, traditional decor, and a busy, welcoming atmosphere.
Moderate for Italy: cafes and casual meals are manageable, but hotels and tourist-area dining near the station cost more.
Service is often included or covered by a coperto. Tipping is not required; round up or leave EUR 1-2 at cafes, 5-10% for great restaurant service.
Official public transport app
Firenze Santa Maria Novella, Florence -> Piazza del Duomo, Florence
The train connection between Pisa Centrale and Firenze Santa Maria Novella is efficient and convenient, making it easy for travelers to explore the beautiful region of Tuscany. The journey typically takes around 1 hour, with multiple daily departures offered by providers such as Regionale, Frecciargento, and Intercity. Whether you're heading to Florence's iconic landmarks or returning from a day in Pisa, these trains provide comfortable travel options that cater to various schedules and budgets.
The train connection between Pisa Centrale and Firenze Santa Maria Novella takes approximately 52 minutes. There are 24 direct connections available each day, making it a convenient option for travelers looking to explore these two beautiful cities in Italy.
The first daily train journey from Pisa Centrale departs at 05:44, providing an early start for travelers looking to explore the beautiful city of Florence. The last train leaves at 21:16, allowing visitors ample time to enjoy a full day in this cultural hub before returning.
The cheapest ticket price for the train connection between Pisa Centrale and Firenze Santa Maria Novella is €9. The average ticket price typically hovers around €9 as well, making this route quite affordable for travelers looking to explore these beautiful Italian cities.
The Florence Cathedral, or Duomo di Firenze, is a stunning masterpiece of Gothic architecture that took over 140 years to complete. Its iconic dome, designed by Filippo Brunelleschi in the early 15th century, not only transformed the skyline of Florence but also represented a significant advancement in engineering techniques during the Renaissance. As you stand beneath its magnificent frescoed ceiling and gaze up at its intricate details, you'll appreciate how this cathedral serves as both a spiritual center and an enduring symbol of Florentine pride.
Next on our journey is the Uffizi Gallery, one of the most renowned art museums in the world that houses an unparalleled collection of masterpieces from artists like Botticelli and Michelangelo. Established in 1584 as part of Francesco I de' Medici's palace complex, it reflects not just artistic brilliance but also political power through centuries. Walking through its hallowed halls allows you to experience firsthand how these works have shaped Western art history while igniting your own passion for creativity.
Finally, we arrive at Ponte Vecchio—a medieval stone bridge famous for its vibrant shops built along it since ancient times. Originally home to butcher shops and tanners who contributed unpleasant odors to nearby waters; today it's lined with exquisite jewelry stores offering unique treasures that capture Italy’s artisanal spirit. This picturesque landmark stands as a testament to resilience throughout history—having survived floods and wars—while providing breathtaking views over the Arno River that will leave you enchanted long after your visit ends.
Find answers to the most common questions about traveling from Pisa Centrale to Florence Santa Maria Novella by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Florence Santa Maria Novella, this guide helps you travel smarter and with confidence.

Most Pisa Centrale to Florence Santa Maria Novella trains use the Pisa Centrale to Firenze Santa Maria Novella station pair. Use this guide to compare Pisa Centrale and Florence Santa Maria Novella train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
Pisa Centrale has practical services for this route, including Wifi, Lockers, Parking, Dining, Taxis, Accessibility, WC, Hotel, Ticket Office, Bike Parking, Bike Rental, and Information Desk.
Food options include: McDonald's, Panetteria Binario 1
There is free Wi-Fi available at the McDonald's.
The ticket office is open Mon - Sun: 06:00 - 20:30. Information desks are located just outside the station on Piazza Vittorio Emanuele II.
Luggage storage is there is a luggage storage office near the end of Platform 1.
Available at Pisa Centrale: Parking, Taxis, WC.
Available at Pisa Centrale: Bike Parking, Bike Rental.
Accessibility facilities are available at Pisa Centrale: Accessible facilities including barrier-free restrooms, elevators, ramps, and disabled parking. Sala Blu mobility assistance available from 07:45 to 22:30 with advanced one-hour notice.
Nearby hotels include Hotel NH Pisa, Hotel La Pace, Hotel Maria.
Firenze Santa Maria Novella is 1 km from Florence city centre. Public transport options include:
Firenze Santa Maria Novella has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Ticket Office, Bike Parking, Bike Rental, Car Rental, and Information Desk.
Food options include: 12oz Coffee Joint, Casa Maioli, Don Nino, Fratelli Cuore, McDonald´s, Panella, Segafredo Zanetti, Spizzico, Venchi, & many more
Free WiFi (30 minutes limit). ATMs are located in the basement in the shopping center next to the Feltrinelli bookshop and between Celio and Mango shops.
The ticket office is open Mon - Sun: 06:00 - 21:00. Information desks are located inside and outside the station.
Luggage storage is provided by KiPoint and located on the ground floor, on the side of Piazza Adua. Open daily from 06:00 to 23:00.
Available at Firenze Santa Maria Novella: Parking, Taxis, WC.
Available at Firenze Santa Maria Novella: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Firenze Santa Maria Novella: Elevators, escalators, step-free access. Mobility assistance is available with the Sala Blu, located next to Platform 1.
Nearby hotels include Hotel Luxor Florence, Joy Hotel Florence, Diplomat Hotel Florence.
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