- Must visit
Pinacoteca di Brera
One of Milan’s premier art museums, known for masterpieces by Raphael, Caravaggio, and Mantegna in the historic Brera district.
Cheapest price
$145
Average price
$207
Fastest journey
14 h
Average duration
15 h 41 m
Trains per day
9
Distance
890 km
The best way to find a cheap train ticket from Palermo Centrale to Milan Centrale is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Palermo Centrale to Milan Centrale will cost around $207 if you buy it on the day, but the cheapest tickets can be found for only $145.
Of the 9 trains that leave Palermo Centrale for Milan Centrale on Sat, Jun 20, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sat, Jun 20 the direct trains cover the 890 km distance in an average of 15 h 41 m but if you time it right, some trains will get you there in just 14 h .
On Sat, Jun 20 the slowest trains will take 16 h 37 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
InterCityNotte 1964
Intercity 730+
InterCityNotte 774 · InterCityNotte 758
Intercity 736+
9994
Intercity 736+
9962
Intercity 736+
8158
Intercity 736+
FRECCIAROSSA 9658
Intercity 736+
9994
InterCityNotte 1954+
FRECCIAROSSA 9612
Intercity 736+
8158
Regionale Veloce 5368+
InterCityNotte 36270+
FRECCIAROSSA 9520Omio recommends booking the train as it is the most popular option from Palermo Centrale to Milan Centrale among Omio's users. If you are prioritising price take the flight with prices starting from $21. For those with little time consider booking a flight which can get you there in 5h 9m. The ticket price range depends on the travel mode: a flight costs an average of $21, and a train costs an average of $93.
Distance: 553 miles (890 km)
Most popular Train | Flight | Bus | Ferry | Driving |
|---|---|---|---|---|
$147 Average price | $86 Average price Cheapest | $103 Average price | $86 Average price | $93 Average price (fuel + tolls) |
16h 21m Average total duration 15h 51m Onboard + 30m Additional time* | 8h 9m Average total duration Fastest 5h 9m Onboard + 3h 0m Additional time* | 17h 19m Average total duration 16h 49m Onboard + 30m Additional time* | 22h 36m Average total duration 21h 36m Onboard + 1h 0m Additional time* | 16h 22m Average total duration (door-to-door) |
![]() Most popular train company | ![]() Most popular airline | ![]() Most popular bus company | ![]() Most popular ferry company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Palermo Centrale to Milan Centrale:
A flight is $0.35 (€0.29) less than a ferry for this route with tickets for a ferry from Palermo Centrale to Milan Centrale costing on average $86 (€71).
A flight is $17 (€14) less than a bus for this route with tickets for a bus from Palermo Centrale to Milan Centrale costing on average $103 (€85).
A flight is $61 (€50) less than a train for this route with tickets for a train from Palermo Centrale to Milan Centrale costing on average $147 (€121).
Other travel options to Milan Centrale take longer:
Train takes on average 15h 51m.
Bus takes on average 16h 49m.
Ferry takes on average 21h 36m.
You'll arrive about 31m sooner (15h 51m by train vs 16h 22m by car). Tickets start at around $147 (€121) compared to roughly $93 (€76) in fuel and tolls — so you're paying a bit more, but getting hours of your day back, a city-centre arrival, and the freedom to work or relax instead of drive.
Direct services run with Intercity Notte.
Driving makes more sense if you're travelling as a group (where fuel costs split several ways), want to stop along the way, or need a car once you arrive.
The table below shows live departures for Palermo Centrale to Milan Centrale trains for today, Friday, June 19. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
Intercity 730+ InterCityNotte 774 · InterCityNotte 758 | 10:10 AM Palermo Centrale | 20h55 | 7:05 AM Milan Centrale | 2 transfers | |
InterCityNotte 1964 | 12:53 PM Palermo Centrale | 22h12 | 11:05 AM Milan Centrale | 0 transfersDirect | |
InterCityNotte 1958+ FRECCIAROSSA 9414 · FRECCIAROSSA 9806 | 8:21 PM Palermo Centrale | 17h04 | 1:25 PM Milan Centrale | 2 transfers | |
InterCityNotte 1958+ FRECCIAROSSA 9624 | 8:21 PM Palermo Centrale | 17h14 | 1:35 PM Milan Centrale | 1 transfer | |
| Saturday, June 20 | |||||
Intercity 736+ 9994 | 7:00 AM Palermo Centrale | 15h15 | 10:15 PM Milan Centrale | 1 transfer | |
Intercity 736+ 9962 | 7:00 AM Palermo Centrale | 17h20 | 12:20 AM Milan Centrale | 1 transfer | |
Intercity 736+ FRECCIAROSSA 9658 | 7:00 AM Palermo Centrale | 14h00 | 9:00 PM Milan Centrale | 1 transfer | |
Intercity 736+ 8158 | 7:00 AM Palermo Centrale | 16h20 | 11:20 PM Milan Centrale | 1 transfer | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare bus, train, flight, and ferry prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Trains from Palermo Centrale to Milan Centrale run on average 7 times per day, taking around 15h 51m. Cheap train tickets for this journey start at $93 (€76) but you can travel from only $21 (€17) by flight.
There are 1 trains per day. The earliest train runs at 05:02, the last at 20:10. The fastest train covers the 553 miles (890 km) distance in 13h 58m.
Distance 553 miles (890 km) |
Average train duration 15h 51m |
Cheapest ticket price $93 (€76) |
Trains per day 7 |
Direct trains 1 |
Fastest train 13h 58m |
First train 5:02 AM |
Last train 8:10 PM |
Cheapest Month Sep |
Cheapest Day Tue |
High Season Jan - Mar |
Low Season Oct - Dec |
Busiest Day Thu |
Least Busy Day Sat |
Discover the best of Milano Centrale — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Milano Centrale trip today.
One of Milan’s premier art museums, known for masterpieces by Raphael, Caravaggio, and Mantegna in the historic Brera district.
Italy’s largest science museum, featuring Leonardo-inspired displays, transport collections, and interactive exhibits in a former monastery.
A major museum of 20th-century Italian art facing Piazza del Duomo, especially noted for Futurist works and its central location.
Milan’s central square and the city’s main gathering point, ideal for first-time visitors and iconic city views.
A charming historic district known for elegant streets, art atmosphere, boutiques, and a classic Milanese walking experience.
Milan’s canal district, very popular for waterside walks, photos, and lively urban atmosphere, especially in the evening.
Milan’s signature saffron risotto, rich with butter and cheese, celebrated for its golden color and elegant, comforting flavor.
A classic Milanese breaded veal cutlet, traditionally cooked in butter and prized as one of the city’s most iconic dishes.
Braised veal shank, often served with risotto alla Milanese, valued for its tender meat and rich marrow-filled sauce.
Long-standing fine dining destination and one of Milan’s best-known vegetarian restaurants, refined and creative in style.
Well-known Milanese restaurant with a modern approach to Lombard classics such as risotto and mondeghili in a stylish setting.
Historic traditional trattoria known for classic Milanese dishes, old-world atmosphere, and a strong local reputation.
Prices are above the Italian average, especially near the station. Casual meals are manageable, but hotels and sit-down dining cost more.
Service is often included or covered by a coperto. Tipping is not mandatory; round up or leave EUR 1-5 for good service. Taxis can be rounded up.
Official public transport app
Milano Centrale, Milan -> Duomo di Milano, Milan
Find answers to the most common questions about traveling from Palermo Centrale to Milan Centrale by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Milan Centrale, this guide helps you travel smarter and with confidence.

Most Palermo Centrale to Milan Centrale trains use the Enna to Milano Centrale station pair, with some services arriving at Milano Porta Garibaldi. Use this guide to compare Palermo Centrale and Milan Centrale train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
Enna is 1 km from Sicily city centre. Public transport options include:
Enna has practical services for this route, including Accessibility.
Accessibility facilities are available at Enna.
Villarosa is 3 km from Sicily city centre. Public transport options include:
Villarosa has practical services for this route, including Accessibility.
Accessibility facilities are available at Villarosa.
Milano Centrale is 2 km from Milan city centre. Public transport options include:
Milano Centrale has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Ticket Office, Bike Parking, Bike Rental, Car Rental, and Information Desk.
Food options include: Venchi, Panzera Coffee, Burger King, Bar Motta, Caffè Napoli, VyTA Boulangerie, Spontini, Starbucks, Dispensa Emilia, McDonald's, & many more
Free WiFi in the station. ATMs are there are ATMs in various locations around the station.
The ticket office is open Mon - Sun: 05:50 - 22:20. Information desks are located next to the ticket office on the ground floor in the shopping gallery.
Luggage storage is provided by KiPoint and located on the ground floor, on the side of Piazza Luigi di Savoia. It is open every day from 06:00 to 23:00.
Available at Milano Centrale: Parking, Taxis, WC.
Available at Milano Centrale: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Milano Centrale: Station is wheelchair accessible, has elevators and the Sala Blu, Trenitalia's office of assistance for disabled travelers, is next to Platform 4.
Nearby hotels include Glam Hotel Milano, NYX MIlan, iQ Hotel Milano.
Milano Porta Garibaldi is 2 km from Milan city centre. Public transport options include:
Milano Porta Garibaldi has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Bike Parking, and Bike Rental.
Food options include: Caffeteria Panni Caldi, Princi, Burgez, Bricco Café, U! Come tu mi vuoi, Autogrill, Culto
Free Wi-Fi in the station. ATMs are located in the main hall.
Available at Milano Porta Garibaldi: Parking, Taxis, WC.
Available at Milano Porta Garibaldi: Bike Parking, Bike Rental.
Accessibility facilities are available at Milano Porta Garibaldi: Accessible facilities such as ticket machines, toilets, and ramps and additional assistance as needed from 07:45 to 22:30.
Nearby hotels include Hotel NH Milano Palazzo Moscova, AC Hotel by Marriott Milano, Tocq Hotel.
Milano Rogoredo is 5 km from Milan city centre. Public transport options include:
Milano Rogoredo has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Car Rental, Information Desk, and Luggage Carts.
Food options include: Ristorante Pizzeria Il Moro, Osteria La Piola
Free. ATMs are available in the train station.
Ticket office support is available at Milano Rogoredo. Information desks are located in the main hall.
Luggage storage is available at Milano Rogoredo. Lost and found is available at the station.
Available at Milano Rogoredo: Parking, Taxis, WC.
Available at Milano Rogoredo: Bike Parking, Car Rental.
Accessibility facilities are available at Milano Rogoredo: Elevators, ramps.
Nearby hotels include Starhotels Business Palace, Hotel Mistral, Hotel Brenta Milano.
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