Palermo Centrale to Florence Santa Maria Novella train with Intercity Notte

Wed, Jul 22
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Intercity Notte
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Italo
Frecciarossa
Regionale
2,000+ travel companies
Intercity Notte
Intercity
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Frecciarossa
Regionale
2,000+ travel companies
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The cheapest and fastest trains from Palermo Centrale to Florence Santa Maria Novella

Showing times and prices for Jul 22

Cheapest price

$128

Average price

$175

Fastest journey

12 h 46 m

Average duration

14 h 30 m

Trains per day

7

Distance

655 km

Cheap tickets

The best way to find a cheap train ticket from Palermo Centrale to Florence Santa Maria Novella is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Palermo Centrale to Florence Santa Maria Novella will cost around $175 if you buy it on the day, but the cheapest tickets can be found for only $128.

Fast trains

It's difficult to get from Palermo Centrale to Florence Santa Maria Novella without transferring at least once.

  • IntercityIntercity 736+RegionaleRegionale Veloce 4110
    7:00 AM16h50
    Palermo Centrale
    11:50 PMFlorence Santa Maria Novella
    $1281One-way
    1 transfer
  • Intercity NotteInterCityNotte 1958+IntercityIntercity 590+RegionaleRegionale 18226
    8:21 PM19h31
    Palermo Centrale
    3:52 PMFlorence Santa Maria Novella
    $1721One-way
    2 transfers
  • Intercity NotteInterCityNotte 1954 · InterCityNotte 89512+RegionaleRegionale Veloce 4020
    5:32 PM17h01
    Palermo Centrale
    10:33 AMFlorence Santa Maria Novella
    $1791One-way
    2 transfers
  • IntercityIntercity 730+FrecciarossaFRECCIAROSSA 9568
    10:10 AM12h48
    Palermo Centrale
    10:58 PMFlorence Santa Maria Novella
    $1821One-way
    1 transfer
  • IntercityIntercity 736+FrecciarossaFRECCIAROSSA 9556
    7:00 AM12h46
    Palermo Centrale
    7:46 PMFlorence Santa Maria Novella
    $1821One-way
    1 transfer

Travel Information

Compare train, bus, flight, and ferry for Palermo Centrale to Florence Santa Maria Novella

Omio recommends booking the train as it is the most popular option from Palermo Centrale to Florence Santa Maria Novella among Omio's users. If you are prioritising price take the ferry with prices starting from $49. For those with little time consider booking a flight which can get you there in 1h 38m. The ticket price range depends on the travel mode: a ferry costs an average of $49, and a train costs an average of $86.

Distance: 406 miles (655 km)

Compare train with

Most popular
Train
Flight
Bus
Ferry
Driving

$131

Average price

$87

Average price

$72

Average price

$59

Average price

Cheapest

$61

Average price

(fuel + tolls)

13h 2m

Average total duration

12h 32m

Onboard

+

30m

Additional time*

4h 38m

Average total duration

Fastest

1h 38m

Onboard

+

3h 0m

Additional time*

16h 45m

Average total duration

16h 15m

Onboard

+

30m

Additional time*

21h 30m

Average total duration

20h 30m

Onboard

+

1h 0m

Additional time*

12h 58m

Average total duration

(door-to-door)

Intercity Notte

Most popular train company

Volotea

Most popular airline

FlixBus

Most popular bus company

Grimaldi

Most popular ferry company

Your own car or car rental

Direct Options

Direct Options

Direct Options

Direct Options

Direct Options

The cheapest way to travel from Palermo Centrale to Florence Santa Maria Novella is a ferry with an average price of $59 (€49).

This is compared to other travel options from Palermo Centrale to Florence Santa Maria Novella:

A ferry is $13 (€10) less than a bus for this route with tickets for a bus from Palermo Centrale to Florence Santa Maria Novella costing on average $72 (€59).

A ferry is $27 (€22) less than a flight for this route with tickets for a flight from Palermo Centrale to Florence Santa Maria Novella costing on average $87 (€71).

A ferry is $71 (€59) less than a train for this route with tickets for a train from Palermo Centrale to Florence Santa Maria Novella costing on average $131 (€107).

The fastest way to travel from Palermo Centrale to Florence Santa Maria Novella is by flight with an average journey time of 1h 38m.

Other travel options to Florence Santa Maria Novella take longer:

Train takes on average 12h 32m.

Bus takes on average 16h 15m.

Ferry takes on average 20h 30m.

It's helpful to compare your options as there are 4 ways to travel between Palermo Centrale and Florence Santa Maria Novella including taking a train, bus, flight, and ferry.
We recommend using the train as it is the most popular way to get from Palermo Centrale to Florence Santa Maria Novella among Omio's users.
Take the train. It's meaningfully faster than driving, and the time saved usually justifies the price.

You'll arrive about 26m sooner (12h 32m by train vs 12h 58m by car). Tickets start at around $131 (€107) compared to roughly $61 (€51) in fuel and tolls — so you're paying a bit more, but getting hours of your day back, a city-centre arrival, and the freedom to work or relax instead of drive.

Driving makes more sense if you're travelling as a group (where fuel costs split several ways), want to stop along the way, or need a car once you arrive.

Live departures

Palermo Centrale to Florence Santa Maria Novella train times

The table below shows live departures for Palermo Centrale to Florence Santa Maria Novella trains for today, Tuesday, July 21. You can also manually refresh the results below to see updated train journeys.

Last updated at
ProviderDepartsDurationArrivesTransfers
Tickets
Intercity NotteInterCityNotte 1958+IntercityIntercity 590+RegionaleRegionale 182268:21 PM Palermo Centrale
19h31
3:52 PM Florence Santa Maria Novella2 transfers
Intercity NotteInterCityNotte 1958+FrecciarossaFRECCIAROSSA 95248:21 PM Palermo Centrale
15h25
11:46 AM Florence Santa Maria Novella1 transfer
Wednesday, July 22
IntercityIntercity 736+RegionaleRegionale Veloce 41107:00 AM Palermo Centrale
16h50
11:50 PM Florence Santa Maria Novella1 transfer
IntercityIntercity 736+FrecciarossaFRECCIAROSSA 95567:00 AM Palermo Centrale
12h46
7:46 PM Florence Santa Maria Novella1 transfer
IntercityIntercity 730+FrecciarossaFRECCIAROSSA 956810:10 AM Palermo Centrale
12h48
10:58 PM Florence Santa Maria Novella1 transfer

Find all the dates and times for this journey

Compare prices and tickets Palermo Centrale to Florence Santa Maria Novella by train, bus, flight, or ferry

Compare train, bus, flight, and ferry prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

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Jul 22
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Jul 26
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Jul 28

Why should you book Palermo Centrale to Florence Santa Maria Novella trains with Omio?

Intercity Notte as well as Intercity, Italo, Frecciarossa, Regionale and more offer trains services from Palermo Centrale to Florence Santa Maria Novella.
Omio is the only official third party seller for Intercity Notte tickets.

Why book with Omio vs Intercity Notte?

  • Compare with other providers: On Omio, you can not only buy tickets for Intercity Notte, but also compare tickets for the likes of Intercity, Italo, Frecciarossa or Regionale to find the best option for your trip from Palermo Centrale to Florence Santa Maria Novella.
  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare Intercity Notte with all available travel options, which are train, bus, flight and ferry to ensure you get the best deal for traveling from Palermo Centrale to Florence Santa Maria Novella.

Journey information

Overview: Train from Palermo Centrale to Florence Santa Maria Novella

ItalyItaly
ItalyItaly
Icon of train

Trains from Palermo Centrale to Florence Santa Maria Novella run on average 6 times per day, taking around 12h 32m. Cheap train tickets for this journey start at $86 (€71) but you can travel from only $21 (€17) by flight.

The earliest train runs at 05:02, the last at 19:25. The fastest train covers the 406 miles (655 km) distance in 12h 43m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $21 (€17)
Distance
406 miles (655 km)
Average train duration
12h 32m
Cheapest ticket price
$86 (€71)
Trains per day
6
Fastest train
12h 43m
First train
5:02 AM
Last train
7:25 PM
Cheapest Month
Sep
Cheapest Day
Wed
High Season
Jan - Mar
Low Season
Oct - Dec
Busiest Day
Thu
Least Busy Day
Mon
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $21 (€17)

Train companies: Intercity Notte, Intercity, Italo, Frecciarossa, Regionale from Palermo Centrale to Florence Santa Maria Novella trainsIntercity Notte, Intercity, Italo, Frecciarossa, Regionale trains will get you between Palermo Centrale and Florence Santa Maria Novella from $21 (€17). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.

Intercity Notte

About
Intercity Notte is an Italian train service operated by Trenitalia. It runs overnight services between major cities in Italy, making it a great option for travelers looking to save time and money. The Intercity Notte offers two types of trains: the Frecciarossa Notte and the Frecciargento Notte. The Frecciarossa Notte is the fastest train, with speeds of up to 300 km/h, while the Frecciargento Notte is slightly slower but still offers a comfortable journey. Both trains offer a range of onboard facilities, including comfortable seating, air conditioning, and Wi-Fi. Trenitalia offers a range of ticket types, including Standard, Comfort, and Business. Standard tickets are the most affordable, while Comfort and Business tickets offer additional benefits such as priority boarding and access to the lounge. The most popular routes for Intercity Notte are Rome to Milan, Rome to Venice, and Milan to Venice. These routes offer travelers the chance to explore some of Italy's most iconic cities in a convenient and comfortable way.
Luggage & cancellation policy
Intercity Notte frequency
3 a day
Luggage included
1 handbag and 1 suitcase included in ticket price
Luggage storage
Luggage racks above seats and at carriage ends
Cancellation Policy
Cancellation possible according to ticket type conditions
Refund
Full refund provided for canceled trains
Amenities on board the train
Wifi
Food sold onboard
Restaurant car with full dining service and bar
Seat reservation
Seat reservation included in ticket price
Toilets
USB plugs
Accessibility
Wheelchair spaces and assistance available for disabled passengers
Pets
Small pets in carriers travel free. Larger dogs require paid ticket and muzzle. Guide dogs free.
Quiet zone

Intercity

About
Trenitalia Intercity is a high-speed train service operated by the Italian national railway company, Trenitalia. It operates throughout the country, with services running from early morning to late evening. The Intercity trains come in two types: the Intercity Plus, which is the fastest and most comfortable, and the Intercity, which is slightly slower but still offers a comfortable journey. Onboard facilities include air conditioning, power sockets, Wi-Fi, and a bar service. There are several ticket types available, including Standard, Super Economy, and Business. The most popular routes for Trenitalia Intercity are from Rome to Milan, Naples to Florence, and Turin to Venice.
Luggage & cancellation policy
Average Duration
16h 42m
Cheapest Price
$86 (€71)
Intercity frequency
3 a day
Luggage included
2 pieces of luggage up to 30kg total
Luggage storage
Overhead racks and designated luggage areas at end of carriages
Cancellation Policy
According to ticket conditions
Refund
Full refund provided
Amenities on board the train
Wifi
Food sold onboard
Restaurant car with hot meals and snacks, trolley service in some trains. But do not count on the presence of a buffet car. So if having access to food and drink on the train is important to you, it’s best to bring your own refreshments onboard.
Seat reservation
Seat reservation included in ticket price for most routes
Toilets
USB plugs
Accessibility
Wheelchair spaces and accessible toilets available
Pets
Small pets in carriers allowed free, larger dogs require paid ticket
Quiet zone

Italo

About
Italo is Italy’s private high-speed train service operated by Nuovo Trasporto Viaggiatori (NTV), connecting major cities such as Rome, Milan, Naples, Florence, Turin, Bologna, and Salerno. Its fleet includes the Italo AGV 575, capable of speeds up to 186 mph (300 km/h), and the eco-friendly Italo EVO, which reaches up to 150 mph (250 km/h). Passengers can choose from four classes — Smart, Comfort, Prima, and Club Executive — all offering modern amenities such as free Wi-Fi, power outlets, reclining leather seats, footrests, bathrooms, snack machines, and Italo Live entertainment with movies, music, and games. Italo offers three fare types — Low Cost, Economy, and Flex — providing different levels of price and flexibility. Popular routes include Rome–Milan, Rome–Florence, and Milan–Turin, making Italo a fast, comfortable, and convenient way to travel around Italy.
Luggage & cancellation policy
Average Duration
14h 32m
Cheapest Price
$120 (€99)
Italo frequency
1 a day
Luggage included
2 pieces of hand luggage (max 55x35x25cm) and 1 piece of luggage (max 75x53x30cm)
Luggage storage
Overhead racks and designated luggage areas between seats
Cancellation Policy
Cancellation possible according to ticket conditions
Refund
Full refund provided for canceled trains
Amenities on board the train
Wifi
Food sold onboard
Snack bar service available in most trains with drinks and light refreshments. Welcome service in Prima and Club Executive classes
Seat reservation
Included in Prima and Club Executive. Optional extra cost in Smart and Comfort
Toilets
USB plugs
Accessibility
Wheelchair spaces and assistance available for passengers with reduced mobility
Pets
Small pets in carriers travel free. Larger dogs require paid ticket and muzzle. Guide dogs travel free
Quiet zone
Learn more about Italo

Frecciarossa

About
Step on board a Frecciarossa train and relax as you travel across Italy. Trenitalia’s Frecciarossa high-speed trains make around 200 connections across the country each day and are renowned for their comfort, speed, and reduced environmental impact. Reaching speeds of up to 186 mph (300 km/h), they connect major destinations such as Rome, Florence, Milan, Venice, and Naples quickly and efficiently. When booking your Frecciarossa journey, you can choose between four classes: Standard, Premium, Business, and Executive. While each class offers different levels of comfort, all provide free Wi-Fi access, power outlets, air conditioning, bathrooms, luggage storage, onboard entertainment, and restaurant and bar services. Ticket options include Super Economy, Economy, and Base, making it easy to find the right balance of comfort and price for your trip.
Luggage & cancellation policy
Average Duration
12h 43m
Cheapest Price
$107 (€88)
Frecciarossa frequency
1 a day
Luggage included
1 carry-on bag and 1 suitcase per passenger
Luggage storage
Overhead racks, dedicated luggage areas at carriage ends, under seats
Cancellation Policy
Refund policy depends on ticket type
Refund
Full refund provided for canceled trains
Amenities on board the train
Wifi
Food sold onboard
Restaurant car with full meals, bar service with snacks and beverages, at-seat service in Executive class
Seat reservation
Included in Executive class, optional fee for other classes
Toilets
USB plugs
Accessibility
Wheelchair spaces, accessible toilets, assistance service available
Pets
Small pets in carriers travel free, larger dogs require paid ticket and muzzle, service animals free
Quiet zone
Learn more about Frecciarossa

Regionale

About
Regionale is the regional train service of national carrier Trenitalia connecting all of Italy. It is the most convinient way to travel to both big cities and the smallest villages all over the Italian country. The regional trains have different names depending on the region they serve, such as Treno Regionale Veloce (TRV) and Treno Regionale Lento (TRL). Treno Rock and Treno pop are the two new trains part of Trenitalia regionale fleet. Trenitalia Regionale offers a variety of ticket types, including single tickets (economy and standard), return tickets, and season tickets. Onboard facilities include free Wi-Fi, air conditioning, and power sockets. The most popular routes for Regionale are between Rome and Milan, Naples and Florence, and Turin and Venice.
Luggage & cancellation policy
Average Duration
16h 40m
Cheapest Price
$88 (€72)
Regionale frequency
1 a day
Luggage included
Free hand luggage allowance included in ticket price
Luggage storage
Overhead racks and designated luggage areas between seats
Cancellation Policy
According to ticket conditions
Refund
Full refund provided
Amenities on board the train
Wifi
Food sold onboard
Bar service available on some trains with snacks and beverages
Seat reservation
Seat reservation included in ticket price for most services
Toilets
USB plugs
Accessibility
Wheelchair spaces and assistance available for passengers with reduced mobility
Pets
Small pets in carriers travel free. Larger dogs require paid ticket and muzzle
Quiet zone

FAQs: Trains from Palermo Centrale to Florence Santa Maria Novella

Find answers to the most common questions about traveling from Palermo Centrale to Florence Santa Maria Novella by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Florence Santa Maria Novella, this guide helps you travel smarter and with confidence.

FAQs
Train ticket prices from Palermo Centrale to Florence Santa Maria Novella can vary. The cheapest ticket starts at $86 (€71), while the average price is around $131 (€107).
The train from Palermo Centrale to Florence Santa Maria Novella takes 12h 43m and runs 6 per day.
The first train from Palermo Centrale to Florence Santa Maria Novella leaves at 5:02 AM.
The distance by train from Palermo Centrale to Florence Santa Maria Novella is 406 miles (655 km).
The last train from Palermo Centrale to Florence Santa Maria Novella leaves at 7:25 PM.
Yes, there is a high-speed train from Palermo Centrale to Florence Santa Maria Novella.
There is no direct train service currently available from Palermo Centrale to Florence Santa Maria Novella.
Yes, there is a night train from Palermo Centrale to Florence Santa Maria Novella.
The cheapest way to get from Palermo Centrale to Florence Santa Maria Novella is by flight, with a cost of around $21 (€17).
The train journey from Palermo Centrale to Firenze Santa Maria Novella offers scenic views, particularly as it traverses the picturesque landscapes of Sicily, including coastal vistas and rolling hills, before crossing the Strait of Messina and continuing through the Tuscan countryside.
A day trip from Palermo Centrale to Firenze Santa Maria Novella is not feasible due to the long travel time of 12h 43m. The journey covers a distance of 406 miles (655 km) with a frequency of 5 trains per day.
Yes, you can take the train from Palermo Centrale to Florence Santa Maria Novella.
Since both Palermo Centrale and Florence Santa Maria Novella are in the Schengen Area, a passport is not required for European Union (EU) or Schengen-associated country citizens. A national ID card is sufficient.
Popular day trips by train from Florence Santa Maria Novella include Pisa, Bologna, Siena, Lucca, Verona.
We recommend using the train as it is the most popular way to get from Palermo Centrale to Florence Santa Maria Novella among Omio's users.
Items not allowed on trains typically include hazardous materials such as explosives, flammable liquids, corrosive substances, and illegal drugs. Additionally, large or bulky items that may obstruct aisles or emergency exits, as well as pets without proper carriers, may be restricted. Specific prohibited items can vary by train operator and region, so please check the rules for your particular journey.
Yes, rail passes such as the Eurail Italy Pass and Interrail Italy Pass are valid on most trains operated by Trenitalia and Italo within Italy, including regional, intercity, and high-speed trains, though some restrictions and seat reservation fees may apply.
Italy uses the euro (EUR) as its currency. Travelers generally find it convenient to use cards for most payments, especially in cities and larger establishments, but carrying some cash is advisable for small shops, markets, and rural areas where card acceptance may be limited.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

popular train stations

Popular train stations from Palermo Centrale to Florence Santa Maria Novella

Most Palermo Centrale to Florence Santa Maria Novella trains use the Enna to Firenze Santa Maria Novella station pair. Use this guide to compare Palermo Centrale and Florence Santa Maria Novella train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.

Departure train stations in Sicily
Arrival train stations in Florence
Firenze Santa Maria NovellaPiazza della Stazione, 1, 50123 Florence, Italy+39 0552352595WifiLockersParkingDiningATMTaxisAccessibilityWCHotelTicket OfficeBike ParkingBike RentalCar RentalInformation Desk
City-centre transport

Getting to Firenze Santa Maria Novella from Florence city centre

Firenze Santa Maria Novella is 1 km from Florence city centre. Public transport options include:

TramT2 · 4m · $2 · every ~21 min

Firenze Santa Maria Novella train station facilities and services

Firenze Santa Maria Novella has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Ticket Office, Bike Parking, Bike Rental, Car Rental, and Information Desk.

Food and drink

Food options include: 12oz Coffee Joint, Casa Maioli, Don Nino, Fratelli Cuore, McDonald´s, Panella, Segafredo Zanetti, Spizzico, Venchi, & many more

Wi-Fi and ATMs

Free WiFi (30 minutes limit). ATMs are located in the basement in the shopping center next to the Feltrinelli bookshop and between Celio and Mango shops.

Tickets and information

The ticket office is open Mon - Sun: 06:00 - 21:00. Information desks are located inside and outside the station.

Luggage and lost property

Luggage storage is provided by KiPoint and located on the ground floor, on the side of Piazza Adua. Open daily from 06:00 to 23:00.

Parking, taxis and toilets

Available at Firenze Santa Maria Novella: Parking, Taxis, WC.

Bike and car services

Available at Firenze Santa Maria Novella: Bike Parking, Bike Rental, Car Rental.

Accessibility

Accessibility facilities are available at Firenze Santa Maria Novella: Elevators, escalators, step-free access. Mobility assistance is available with the Sala Blu, located next to Platform 1.

Shops, hotels and contact

Nearby hotels include Hotel Luxor Florence, Joy Hotel Florence, Diplomat Hotel Florence.

More about Firenze Santa Maria Novella

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