The cheapest and fastest trains from Palermo Centrale to Florence Santa Maria Novella
Cheapest price
$121
Average price
$126
Fastest journey
12 h 5 m
Average duration
14 h 25 m
Trains per day
2
Distance
655 km
The best way to find a cheap train ticket from Palermo Centrale to Florence Santa Maria Novella is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Palermo Centrale to Florence Santa Maria Novella will cost around $126 if you buy it on the day, but the cheapest tickets can be found for only $121.
Of the 2 trains that leave Palermo Centrale for Florence Santa Maria Novella on Sat, Dec 06, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sat, Dec 06 the direct trains cover the 655 km distance in an average of 14 h 25 m but if you time it right, some trains will get you there in just 12 h 5 m .
On Sat, Dec 06 the slowest trains will take 16 h 45 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.




Travel Information
Compare train, bus, flight, and ferry for Palermo Centrale to Florence Santa Maria Novella
Omio recommends booking the train as it is the most popular option from Palermo Centrale to Florence Santa Maria Novella among Omio's users. If you are prioritising price take the ferry with prices starting from €40. For those with little time consider booking a flight which can get you there in 1h 47m. The ticket price range depends on the travel mode: a ferry costs an average of €40, and a flight costs an average of €33.
Distance: 406 miles (655 km)
Compare train with
Most popular Train | Flight | Bus | Ferry |
|---|---|---|---|
€104 Average price | €132 Average price | €77 Average price | €66 Average price Cheapest |
13h 1m Average total duration 12h 31m Onboard + 30m Additional time* | 4h 47m Average total duration Fastest 1h 47m Onboard + 3h 0m Additional time* | 15h 30m Average total duration 15h 0m Onboard + 30m Additional time* | 21h 30m Average total duration 20h 30m Onboard + 1h 0m Additional time* |
![]() Most popular train company | ![]() Most popular airline | ![]() Most popular bus company | ![]() Most popular ferry company |
Direct Options | Direct Options | Direct Options | Direct Options |
Live departures
Palermo Centrale to Florence Santa Maria Novella train times
The table below shows live departures for Palermo Centrale to Florence Santa Maria Novella trains for today, Friday, December 5. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 3:20 PM Palermo Centrale | 15h07 | 6:27 AM Florence Santa Maria Novella | 0 transfersDirect | |
| Saturday, December 6 | |||||
![]() | 5:05 AM Palermo Centrale | 16h45 | 9:50 PM Florence Santa Maria Novella | 0 transfersDirect | |
![]() | 8:15 AM Palermo Centrale | 12h05 | 8:20 PM Florence Santa Maria Novella | 0 transfersDirect | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Palermo Centrale to Florence Santa Maria Novella by train, bus, flight, or ferry
Compare train, bus, flight, and ferry prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Dec 06
Dec 07
Dec 08
Dec 09
Dec 10
Dec 11
Dec 12
Journey information
Overview: Train from Palermo Centrale to Florence Santa Maria Novella
Trains from Palermo Centrale to Florence Santa Maria Novella run on average 5 times per day, taking around 12h 31m. Cheap train tickets for this journey start at $75 (€60) but you can travel from only $41 (€33) by flight.
The earliest train runs at 03:07, the last at 19:10. The fastest train covers the 406 miles (655 km) distance in 12h 39m.
Distance 406 miles (655 km) |
Average train duration 12h 31m |
Cheapest ticket price $75 (€60) |
Trains per day 5 |
Fastest train 12h 39m |
First train 03:07 |
Last train 19:10 |
Train companies: Intercity, Intercity Notte, Italo, Frecciarossa from Palermo Centrale to Florence Santa Maria Novella trainsIntercity, Intercity Notte, Italo, Frecciarossa trains will get you between Palermo Centrale and Florence Santa Maria Novella from $41 (€33). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Intercity
Intercity Notte
Italo
Frecciarossa
FAQs: Trains from Palermo Centrale to Florence Santa Maria Novella
Find answers to the most common questions about traveling from Palermo Centrale to Florence Santa Maria Novella by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Florence Santa Maria Novella, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Palermo Centrale to Florence Santa Maria Novella
- Mon - Sun: 06:00 - 21:00
- Free WiFi (30 minutes limit).
- Provided by KiPoint and located on the ground floor, on the side of Piazza Adua. Open daily from 06:00 to 23:00.
- 12oz Coffee Joint
- Casa Maioli
- Don Nino
- Fratelli Cuore
- McDonald´s
- Panella
- Segafredo Zanetti
- Spizzico
- Venchi
- & many more
- Elevators, escalators, step-free access. Mobility assistance is available with the Sala Blu, located next to Platform 1.
- Hotel Luxor Florence
- Joy Hotel Florence
- Diplomat Hotel Florence
- Mon - Sun: 06:00 - 21:00
- Located inside and outside the station.
- Tram lines: T1, T2
- Bus lines: 6, 11, 12, 13, 17, 23, 36, 37, C4
- Train lines: FR, FA, Italo
Most popular train connections from Palermo Centrale
More options for your journey from Palermo Centrale to Florence Santa Maria Novella
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