The cheapest and fastest trains from Milan Centrale to Palermo Centrale
Cheapest price on Sep 20
$143
Average ticket price on Sep 20
$219
Fastest journey on Sep 20
14 h 28 m
Average journey duration on Sep 20
16 h 54 m
Trains on Sep 20
7
Distance
890 km
The best way to find a cheap train ticket from Milan Centrale to Palermo Centrale is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Milan Centrale to Palermo Centrale will cost around $219 if you buy it on the day, but the cheapest tickets can be found for only $143.
On Sun, Sep 20, we found 7 trains from Milan Centrale to Palermo Centrale, including 1 direct services.
On Sun, Sep 20 the direct trains cover the 890 km distance in an average of 16 h 54 m but if you time it right, some trains will get you there in just 14 h 28 m .
On Sun, Sep 20 the slowest trains will take 20 h 45 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
InterCityNotte 19638:10 PM20h45Milan Centrale4:55 PMPalermo Centrale$1431One-way0 transfers
FRECCIAROSSA 9613+
Intercity 7278:30 AM14h28Milan Centrale10:58 PMPalermo Centrale$2031One-way1 transfer
Intercity 1549 · Intercity 511+
InterCityNotte 195510:05 AM23h08Milan Centrale9:13 AMPalermo Centrale$2141One-way2 transfers
Intercity 597 · Intercity 594+
InterCityNotte 19591:48 PM23h24Milan Centrale1:12 PMPalermo Centrale$2181One-way2 transfers
FRECCIAROSSA 9555+
InterCityNotte 19555:10 PM16h03Milan Centrale9:13 AMPalermo Centrale$2331One-way1 transfer
FRECCIAROSSA 9613+
Intercity 7278:30 AM14h28Milan Centrale10:58 PMPalermo Centrale$2031One-way1 transfer
FRECCIAROSSA 9651 · FRECCIAROSSA 9555+
InterCityNotte 19555:35 PM15h38Milan Centrale9:13 AMPalermo Centrale$2821One-way2 transfers
FRECCIAROSSA 9555+
InterCityNotte 19555:10 PM16h03Milan Centrale9:13 AMPalermo Centrale$2331One-way1 transfer
FRECCIAROSSA 9663+
InterCityNotte 19597:35 PM17h37Milan Centrale1:12 PMPalermo Centrale$2411One-way1 transfer
InterCityNotte 19638:10 PM20h45Milan Centrale4:55 PMPalermo Centrale$1431One-way0 transfers
Travel Information
Compare train, bus, flight, and ferry for Milan Centrale to Palermo Centrale
Omio recommends booking the train as it is the most popular option from Milan Centrale to Palermo Centrale among Omio's users. If you are prioritising price, take the ferry, with an average ticket price of $97 For those with little time, consider booking a flight, which has an average total journey time of 4h 9m. Average ticket prices depend on the travel mode: a ferry costs an average of $97, while a flight costs an average of $245.
Distance: 553 miles (890 km)
Compare train with
Most popular Train | Bus | Flight | Ferry | Driving |
|---|---|---|---|---|
$114 Average price | $119 Average price | $245 Average price | $97 Average price Cheapest | $122 Average price (fuel + tolls) |
16h 50m Average total duration 16h 20m Onboard + 30m Additional time* | 22h 43m Average total duration 22h 13m Onboard + 30m Additional time* | 4h 9m Average total duration Fastest 2h 9m Onboard + 2h 0m Additional time* | 21h 11m Average total duration 20h 11m Onboard + 1h 0m Additional time* | 26h 21m Average total duration (door-to-door) |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular ferry company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Milan Centrale to Palermo Centrale:
A ferry is $18 less than a train for this route with tickets for a train from Milan Centrale to Palermo Centrale costing on average $114.
A ferry is $23 less than a bus for this route with tickets for a bus from Milan Centrale to Palermo Centrale costing on average $119.
A ferry is $149 less than a flight for this route with tickets for a flight from Milan Centrale to Palermo Centrale costing on average $245.
Other travel options to Palermo Centrale take longer:
Train takes on average 16h 20m.
Ferry takes on average 20h 11m.
Bus takes on average 22h 13m.
The journey is about 10h 1m faster (16h 20m by train vs 26h 21m by car) and roughly $7 cheaper once you factor in fuel and tolls ($114 vs $122). You'll also arrive in the city centre rather than hunting for parking, and you can work, read, or watch the landscape go by instead of concentrating on the road.
Direct services run with Intercity Notte.
Driving is still worth considering if you want to stop along the way or need a car once you arrive.
Live departures
Milan Centrale to Palermo Centrale train times
The table below shows live departures for Milan Centrale to Palermo Centrale trains for today, Saturday, September 19. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FRECCIAROSSA 9613+ Intercity 727 | 8:30 AM Milan Centrale | 14h28 | 10:58 PM Palermo Centrale | 1 transfer | |
Intercity 1549 · Intercity 511+ InterCityNotte 1955 | 9:30 AM Milan Centrale | 23h43 | 9:13 AM Palermo Centrale | 2 transfers | |
Intercity 597 · Intercity 594+ InterCityNotte 1959 | 1:48 PM Milan Centrale | 23h24 | 1:12 PM Palermo Centrale | 2 transfers | |
FRECCIAROSSA 9653+ InterCityNotte 1955 | 6:00 PM Milan Centrale | 15h13 | 9:13 AM Palermo Centrale | 1 transfer | |
InterCityNotte 1963 | 7:05 PM Milan Centrale | 21h50 | 4:55 PM Palermo Centrale | 0 transfersDirect | |
FRECCIAROSSA 9663+ InterCityNotte 1959 | 7:35 PM Milan Centrale | 17h37 | 1:12 PM Palermo Centrale | 1 transfer | |
FRECCIAROSSA 9567+ InterCityNotte 1963 | 8:10 PM Milan Centrale | 20h45 | 4:55 PM Palermo Centrale | 1 transfer | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Milan Centrale to Palermo Centrale by train, bus, flight, or ferry
Compare train, bus, flight, and ferry prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Milan Centrale to Palermo Centrale trains with Omio?
Why book with Omio vs Intercity Notte?
- Compare with other providers: On Omio, you can not only buy tickets for Intercity Notte, but also compare tickets for the likes of Intercity, Italo, Frecciarossa or Frecciargento to find the best option for your trip from Milan Centrale to Palermo Centrale.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Intercity Notte with all available travel options, which are train, bus, flight and ferry to ensure you get the best deal for traveling from Milan Centrale to Palermo Centrale.
Journey information
Overview: Train from Milan Centrale to Palermo Centrale
Trains from Milan Centrale to Palermo Centrale run on average 20 times per day, taking around 16h 20m. Cheap train tickets for this journey start at $35 but you can travel from only $21 by flight.
There are 1 trains per day. The earliest train runs at 04:40, the last at 19:50. The fastest train covers the 553 miles (890 km) distance in 13h 12m.
Distance 553 miles (890 km) |
Average train duration 16h 20m |
Cheapest ticket price $35 |
Trains per day 20 |
Direct trains 1 |
Fastest train 13h 12m |
First train 4:40 AM |
Last train 7:50 PM |
Cheapest Month Nov |
Cheapest Day Wed |
High Season Jul - Sep |
Low Season Oct - Dec |
Busiest Day Fri |
Least Busy Day Sat |
Best time to book 35 days |
Train companies: Intercity Notte, Intercity from Milan Centrale to Palermo Centrale trainsIntercity Notte, Intercity trains will get you between Milan Centrale and Palermo Centrale from $21. With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Intercity Notte
Intercity
FAQs: Trains from Milan Centrale to Palermo Centrale
Find answers to the most common questions about traveling from Milan Centrale to Palermo Centrale by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Palermo Centrale, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Milan Centrale to Palermo Centrale
Most Milan Centrale to Palermo Centrale trains use the Milano Centrale to Enna station pair. Use this guide to compare Milan Centrale and Palermo Centrale train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
Getting to Milano Centrale from Milan city centre
Milano Centrale is 2 km from Milan city centre. Public transport options include:
Milano Centrale train station facilities and services
Milano Centrale has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Ticket Office, Bike Parking, Bike Rental, Car Rental, and Information Desk.
Food and drink
Food options include: Venchi, Panzera Coffee, Burger King, Bar Motta, Caffè Napoli, VyTA Boulangerie, Spontini, Starbucks, Dispensa Emilia, McDonald's, & many more
Wi-Fi and ATMs
Free WiFi in the station. ATMs are there are ATMs in various locations around the station.
Tickets and information
The ticket office is open Mon - Sun: 05:50 - 22:20. Information desks are located next to the ticket office on the ground floor in the shopping gallery.
Luggage and lost property
Luggage storage is provided by KiPoint and located on the ground floor, on the side of Piazza Luigi di Savoia. It is open every day from 06:00 to 23:00.
Parking, taxis and toilets
Available at Milano Centrale: Parking, Taxis, WC.
Bike and car services
Available at Milano Centrale: Bike Parking, Bike Rental, Car Rental.
Accessibility
Accessibility facilities are available at Milano Centrale: Station is wheelchair accessible, has elevators and the Sala Blu, Trenitalia's office of assistance for disabled travelers, is next to Platform 4.
Shops, hotels and contact
Nearby hotels include Glam Hotel Milano, NYX MIlan, iQ Hotel Milano.
Most popular train connections from Milan Centrale
More options for your journey from Milan Centrale to Palermo Centrale
Here are some other resources that might have the information you need



