The cheapest and fastest trains from Milan Centrale to Palermo Centrale
Cheapest price
$147
Average price
$251
Fastest journey
14 h 31 m
Average duration
15 h 2 m
Trains per day
70
Distance
890 km
The best way to find a cheap train ticket from Milan Centrale to Palermo Centrale is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Milan Centrale to Palermo Centrale will cost around $251 if you buy it on the day, but the cheapest tickets can be found for only $147.
Of the 70 trains that leave Milan Centrale for Palermo Centrale on Thu, May 07, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Thu, May 07 the direct trains cover the 890 km distance in an average of 15 h 2 m but if you time it right, some trains will get you there in just 14 h 31 m .
On Thu, May 07 the slowest trains will take 15 h 21 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
InterCityNotte 19638:10 PM20h45Milan Centrale4:55 PMPalermo Centrale$1471One-way0 transfers
FRECCIAROSSA 9613+
Intercity 7278:30 AM14h31Milan Centrale11:01 PMPalermo Centrale$2091One-way1 transfer
9941+
Intercity 7277:45 AM15h16Milan Centrale11:01 PMPalermo Centrale$2141One-way1 transfer
9969+
Intercity 7276:45 AM16h16Milan Centrale11:01 PMPalermo Centrale$2141One-way1 transfer
9967+
Intercity 7276:15 AM16h46Milan Centrale11:01 PMPalermo Centrale$2141One-way1 transfer
FRECCIAROSSA 9613+
Intercity 7278:30 AM14h31Milan Centrale11:01 PMPalermo Centrale$2091One-way1 transfer
9998+
FRECCIAROSSA 9519+
Intercity 7278:15 AM14h46Milan Centrale11:01 PMPalermo Centrale$2531One-way2 transfers
9941+
Intercity 7277:45 AM15h16Milan Centrale11:01 PMPalermo Centrale$2141One-way1 transfer
9941+
FRECCIAROSSA 9519+
Intercity 7277:45 AM15h16Milan Centrale11:01 PMPalermo Centrale$2531One-way2 transfers
9917+
FRECCIAROSSA 9519+
Intercity 7277:40 AM15h21Milan Centrale11:01 PMPalermo Centrale$2531One-way2 transfers
Travel Information
Compare train, bus, flight, and ferry for Milan Centrale to Palermo Centrale
Omio recommends booking the train as it is the most popular option from Milan Centrale to Palermo Centrale among Omio's users. If you are prioritising price take the bus with prices starting from $34. For those with little time consider booking a flight which can get you there in 1h 43m. The ticket price range depends on the travel mode: a bus costs an average of $34, and a train costs an average of $83.
Distance: 553 miles (890 km)
Compare train with
Most popular Train | Flight | Bus | Ferry | Driving |
|---|---|---|---|---|
$151 Average price | $105 Average price | $82 Average price Cheapest | $90 Average price | $125 Average price (fuel + tolls) |
15h 16m Average total duration 14h 46m Onboard + 30m Additional time* | 4h 43m Average total duration Fastest 1h 43m Onboard + 3h 0m Additional time* | 20h 52m Average total duration 20h 22m Onboard + 30m Additional time* | 21h 23m Average total duration 20h 23m Onboard + 1h 0m Additional time* | 26h 21m Average total duration (door-to-door) |
![]() Most popular train company | ![]() Most popular airline | ![]() Most popular bus company | ![]() Most popular ferry company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Milan Centrale to Palermo Centrale:
A bus is $8 (€6) less than a ferry for this route with tickets for a ferry from Milan Centrale to Palermo Centrale costing on average $90 (€72).
A bus is $23 (€18) less than a flight for this route with tickets for a flight from Milan Centrale to Palermo Centrale costing on average $105 (€84).
A bus is $69 (€55) less than a train for this route with tickets for a train from Milan Centrale to Palermo Centrale costing on average $151 (€121).
Other travel options to Palermo Centrale take longer:
Train takes on average 14h 46m.
Bus takes on average 20h 22m.
Ferry takes on average 20h 23m.
You'll arrive about 11h 35m sooner (14h 46m by train vs 26h 21m by car). Tickets start at around $151 (€121) compared to roughly $125 (€100) in fuel and tolls — so you're paying a bit more, but getting hours of your day back, a city-centre arrival, and the freedom to work or relax instead of drive.
Direct services run with Intercity Notte.
Driving makes more sense if you're travelling as a group (where fuel costs split several ways), want to stop along the way, or need a car once you arrive.
Live departures
Milan Centrale to Palermo Centrale train times
The table below shows live departures for Milan Centrale to Palermo Centrale trains for today, Wednesday, May 6. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FRECCIAROSSA 9663+ InterCityNotte 1959 | 7:35 PM Milan Centrale | 18h08 | 1:43 PM Palermo Centrale | 1 transfer | |
InterCityNotte 1963 | 8:10 PM Milan Centrale | 20h45 | 4:55 PM Palermo Centrale | 0 transfersDirect | |
| Thursday, May 7 | |||||
9907+ FRECCIAROSSA 9519+ Intercity 727 | 5:40 AM Milan Centrale | 17h21 | 11:01 PM Palermo Centrale | 2 transfers | |
9907+ Intercity 727 | 5:40 AM Milan Centrale | 17h21 | 11:01 PM Palermo Centrale | 1 transfer | |
9967+ Intercity 727 | On time 6:15 AM Milan Centrale | 16h46 | 11:01 PM Palermo Centrale | 1 transfer | |
9967+ FRECCIAROSSA 9519+ Intercity 727 | On time 6:15 AM Milan Centrale | 16h46 | 11:01 PM Palermo Centrale | 2 transfers | |
8111+ FRECCIAROSSA 9519+ Intercity 727 | 6:40 AM Milan Centrale | 16h21 | 11:01 PM Palermo Centrale | 2 transfers | |
8111+ Intercity 727 | 6:40 AM Milan Centrale | 16h21 | 11:01 PM Palermo Centrale | 1 transfer | |
9969+ Intercity 727 | On time 6:45 AM Milan Centrale | 16h16 | 11:01 PM Palermo Centrale | 1 transfer | |
9969+ FRECCIAROSSA 9519+ Intercity 727 | On time 6:45 AM Milan Centrale | 16h16 | 11:01 PM Palermo Centrale | 2 transfers | |
9971+ Intercity 727 | 7:15 AM Milan Centrale | 15h46 | 11:01 PM Palermo Centrale | 1 transfer | |
9971+ FRECCIAROSSA 9519+ Intercity 727 | 7:15 AM Milan Centrale | 15h46 | 11:01 PM Palermo Centrale | 2 transfers | |
9917+ FRECCIAROSSA 9519+ Intercity 727 | On time 7:40 AM Milan Centrale | 15h21 | 11:01 PM Palermo Centrale | 2 transfers | |
9941+ Intercity 727 | On time 7:45 AM Milan Centrale | 15h16 | 11:01 PM Palermo Centrale | 1 transfer | |
9941+ FRECCIAROSSA 9519+ Intercity 727 | On time 7:45 AM Milan Centrale | 15h16 | 11:01 PM Palermo Centrale | 2 transfers | |
9998+ FRECCIAROSSA 9519+ Intercity 727 | On time 8:15 AM Milan Centrale | 14h46 | 11:01 PM Palermo Centrale | 2 transfers | |
FRECCIAROSSA 9613+ Intercity 727 | 8:30 AM Milan Centrale | 14h31 | 11:01 PM Palermo Centrale | 1 transfer | |
9919+ InterCityNotte 1955 | 8:40 AM Milan Centrale | 24h28 | 9:08 AM Palermo Centrale | 1 transfer | |
Intercity 659 · Intercity 511+ InterCityNotte 1955 | 9:10 AM Milan Centrale | 23h58 | 9:08 AM Palermo Centrale | 2 transfers | |
9975+ InterCityNotte 1955 | On time 9:15 AM Milan Centrale | 23h53 | 9:08 AM Palermo Centrale | 1 transfer | |
9923+ FRECCIAROSSA 9555+ InterCityNotte 1955 | On time 9:40 AM Milan Centrale | 23h28 | 9:08 AM Palermo Centrale | 2 transfers | |
9923+ InterCityNotte 1955 | On time 9:40 AM Milan Centrale | 23h28 | 9:08 AM Palermo Centrale | 1 transfer | |
9977+ FRECCIAROSSA 9555+ InterCityNotte 1955 | On time 10:15 AM Milan Centrale | 22h53 | 9:08 AM Palermo Centrale | 2 transfers | |
9977+ InterCityNotte 1955 | On time 10:15 AM Milan Centrale | 22h53 | 9:08 AM Palermo Centrale | 1 transfer | |
9927+ InterCityNotte 1955 | On time 10:40 AM Milan Centrale | 22h28 | 9:08 AM Palermo Centrale | 1 transfer | |
9927+ FRECCIAROSSA 9555+ InterCityNotte 1955 | On time 10:40 AM Milan Centrale | 22h28 | 9:08 AM Palermo Centrale | 2 transfers | |
9979+ FRECCIAROSSA 9555+ InterCityNotte 1955 | On time 11:15 AM Milan Centrale | 21h53 | 9:08 AM Palermo Centrale | 2 transfers | |
9979+ InterCityNotte 1955 | On time 11:15 AM Milan Centrale | 21h53 | 9:08 AM Palermo Centrale | 1 transfer | |
9931+ InterCityNotte 1955 | On time 11:40 AM Milan Centrale | 21h28 | 9:08 AM Palermo Centrale | 1 transfer | |
9931+ FRECCIAROSSA 9555+ InterCityNotte 1955 | On time 11:40 AM Milan Centrale | 21h28 | 9:08 AM Palermo Centrale | 2 transfers | |
9981+ InterCityNotte 1959 | On time 12:20 PM Milan Centrale | 25h23 | 1:43 PM Palermo Centrale | 1 transfer | |
9981+ FRECCIAROSSA 9555+ InterCityNotte 1955 | On time 12:20 PM Milan Centrale | 20h48 | 9:08 AM Palermo Centrale | 2 transfers | |
9981+ InterCityNotte 1955 | On time 12:20 PM Milan Centrale | 20h48 | 9:08 AM Palermo Centrale | 1 transfer | |
9935+ FRECCIAROSSA 9555+ InterCityNotte 1955 | On time 12:40 PM Milan Centrale | 20h28 | 9:08 AM Palermo Centrale | 2 transfers | |
9935+ InterCityNotte 1955 | On time 12:40 PM Milan Centrale | 20h28 | 9:08 AM Palermo Centrale | 1 transfer | |
9935+ InterCityNotte 1959 | On time 12:40 PM Milan Centrale | 25h03 | 1:43 PM Palermo Centrale | 1 transfer | |
9983+ InterCityNotte 1959 | On time 1:20 PM Milan Centrale | 24h23 | 1:43 PM Palermo Centrale | 1 transfer | |
9983+ FRECCIAROSSA 9555+ InterCityNotte 1955 | On time 1:20 PM Milan Centrale | 19h48 | 9:08 AM Palermo Centrale | 2 transfers | |
9983+ InterCityNotte 1955 | On time 1:20 PM Milan Centrale | 19h48 | 9:08 AM Palermo Centrale | 1 transfer | |
9939+ FRECCIAROSSA 9555+ InterCityNotte 1955 | On time 1:40 PM Milan Centrale | 19h28 | 9:08 AM Palermo Centrale | 2 transfers | |
9939+ InterCityNotte 1955 | On time 1:40 PM Milan Centrale | 19h28 | 9:08 AM Palermo Centrale | 1 transfer | |
9939+ InterCityNotte 1959 | On time 1:40 PM Milan Centrale | 24h03 | 1:43 PM Palermo Centrale | 1 transfer | |
Intercity 597 · Intercity 594+ InterCityNotte 1959 | 1:48 PM Milan Centrale | 23h55 | 1:43 PM Palermo Centrale | 2 transfers | |
9985+ InterCityNotte 1959 | On time 2:20 PM Milan Centrale | 23h23 | 1:43 PM Palermo Centrale | 1 transfer | |
9985+ FRECCIAROSSA 9555+ InterCityNotte 1955 | On time 2:20 PM Milan Centrale | 18h48 | 9:08 AM Palermo Centrale | 2 transfers | |
9985+ InterCityNotte 1955 | On time 2:20 PM Milan Centrale | 18h48 | 9:08 AM Palermo Centrale | 1 transfer | |
8143+ InterCityNotte 1959 | 2:40 PM Milan Centrale | 23h03 | 1:43 PM Palermo Centrale | 1 transfer | |
8143+ FRECCIAROSSA 9555+ InterCityNotte 1955 | 2:40 PM Milan Centrale | 18h28 | 9:08 AM Palermo Centrale | 2 transfers | |
8143+ InterCityNotte 1955 | 2:40 PM Milan Centrale | 18h28 | 9:08 AM Palermo Centrale | 1 transfer | |
9987+ InterCityNotte 1955 | On time 3:15 PM Milan Centrale | 17h53 | 9:08 AM Palermo Centrale | 1 transfer | |
9987+ FRECCIAROSSA 9555+ InterCityNotte 1955 | On time 3:15 PM Milan Centrale | 17h53 | 9:08 AM Palermo Centrale | 2 transfers | |
9987+ InterCityNotte 1959 | On time 3:15 PM Milan Centrale | 22h28 | 1:43 PM Palermo Centrale | 1 transfer | |
9947+ FRECCIAROSSA 9555+ InterCityNotte 1955 | On time 3:40 PM Milan Centrale | 17h28 | 9:08 AM Palermo Centrale | 2 transfers | |
9947+ InterCityNotte 1959 | On time 3:40 PM Milan Centrale | 22h03 | 1:43 PM Palermo Centrale | 1 transfer | |
9947+ InterCityNotte 1955 | On time 3:40 PM Milan Centrale | 17h28 | 9:08 AM Palermo Centrale | 1 transfer | |
9989+ InterCityNotte 1959 | On time 4:15 PM Milan Centrale | 21h28 | 1:43 PM Palermo Centrale | 1 transfer | |
9989+ FRECCIAROSSA 9555+ InterCityNotte 1955 | On time 4:15 PM Milan Centrale | 16h53 | 9:08 AM Palermo Centrale | 2 transfers | |
9989+ InterCityNotte 1955 | On time 4:15 PM Milan Centrale | 16h53 | 9:08 AM Palermo Centrale | 1 transfer | |
9951+ FRECCIAROSSA 9555+ InterCityNotte 1955 | 4:40 PM Milan Centrale | 16h28 | 9:08 AM Palermo Centrale | 2 transfers | |
9951+ InterCityNotte 1959 | 4:40 PM Milan Centrale | 21h03 | 1:43 PM Palermo Centrale | 1 transfer | |
FRECCIAROSSA 9555+ InterCityNotte 1955 | 5:10 PM Milan Centrale | 15h58 | 9:08 AM Palermo Centrale | 1 transfer | |
9991+ FRECCIAROSSA 9555+ InterCityNotte 1955 | 5:15 PM Milan Centrale | 15h53 | 9:08 AM Palermo Centrale | 2 transfers | |
9991+ InterCityNotte 1959 | 5:15 PM Milan Centrale | 20h28 | 1:43 PM Palermo Centrale | 1 transfer | |
FRECCIAROSSA 9651 · FRECCIAROSSA 9555+ InterCityNotte 1955 | 5:35 PM Milan Centrale | 15h33 | 9:08 AM Palermo Centrale | 2 transfers | |
9955+ InterCityNotte 1959 | 5:40 PM Milan Centrale | 20h03 | 1:43 PM Palermo Centrale | 1 transfer | |
9993+ InterCityNotte 1959 | 5:45 PM Milan Centrale | 19h58 | 1:43 PM Palermo Centrale | 1 transfer | |
9995+ InterCityNotte 1959 | 6:20 PM Milan Centrale | 19h23 | 1:43 PM Palermo Centrale | 1 transfer | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Milan Centrale to Palermo Centrale by train, bus, flight, or ferry
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Why should you book Milan Centrale to Palermo Centrale trains with Omio?
Why book with Omio vs Intercity Notte?
- Compare with other providers: On Omio, you can not only buy tickets for Intercity Notte, but also compare tickets for the likes of Intercity, Italo, Frecciargento or Frecciarossa to find the best option for your trip from Milan Centrale to Palermo Centrale.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Intercity Notte with all available travel options, which are train, bus, flight and ferry to ensure you get the best deal for traveling from Milan Centrale to Palermo Centrale.
Journey information
Overview: Train from Milan Centrale to Palermo Centrale
Trains from Milan Centrale to Palermo Centrale run on average 6 times per day, taking around 14h 46m. Cheap train tickets for this journey start at $83 (€66) but you can travel from only $22 (€17) by flight.
There are 1 trains per day. The earliest train runs at 06:30, the last at 20:25. The fastest train covers the 553 miles (890 km) distance in 14h 25m.
Distance 553 miles (890 km) |
Average train duration 14h 46m |
Cheapest ticket price $83 (€66) |
Trains per day 6 |
Direct trains 1 |
Fastest train 14h 25m |
First train 6:30 AM |
Last train 8:25 PM |
Cheapest Month Nov |
Cheapest Day Sat |
High Season Jan - Mar |
Low Season Oct - Dec |
Busiest Day Fri |
Least Busy Day Mon |
Train companies: Intercity Notte, Intercity, Italo, Frecciargento, Frecciarossa from Milan Centrale to Palermo Centrale trainsIntercity Notte, Intercity, Italo, Frecciargento, Frecciarossa trains will get you between Milan Centrale and Palermo Centrale from $22 (€17). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Intercity Notte
Intercity
Italo
Frecciargento
Frecciarossa
FAQs: Trains from Milan Centrale to Palermo Centrale
Find answers to the most common questions about traveling from Milan Centrale to Palermo Centrale by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Palermo Centrale, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Milan Centrale to Palermo Centrale
- Mon - Sun: 05:50 - 22:20
- Free WiFi in the station.
- Provided by KiPoint and located on the ground floor, on the side of Piazza Luigi di Savoia. It is open every day from 06:00 to 23:00.
- Venchi
- Panzera Coffee
- Burger King
- Bar Motta
- Caffè Napoli
- VyTA Boulangerie
- Spontini
- Starbucks
- Dispensa Emilia
- McDonald's
- & many more
- Station is wheelchair accessible, has elevators and the Sala Blu, Trenitalia's office of assistance for disabled travelers, is next to Platform 4.
- Glam Hotel Milano
- NYX MIlan
- iQ Hotel Milano
- Mon - Sun: 05:50 - 22:20
- Located next to the ticket office on the ground floor in the shopping gallery.
- Metro lines: M2 (green), M3 (yellow)
- Tram lines: 1
- Bus lines: 5, 9, 10, 42, 81, 87, 152, 728, N26, NM2, NM3, Air Bus, Orio Shuttle
- Train lines: FR, FB, EC, Thello, XP2, R28, IC, ICN, RV, R, Regio, Italo
Most popular train connections from Milan Centrale
More options for your journey from Milan Centrale to Palermo Centrale
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