- Must visit
National Museum
Major museum of Czech history and natural sciences in a monumental Neo-Renaissance building overlooking Wenceslas Square.
Cheapest price on Sep 19
€50
Average ticket price on Sep 19
€100
Fastest journey on Sep 19
7 h 32 m
Average journey duration on Sep 19
7 h 52 m
Trains on Sep 19
5
Distance
506 km
The best way to find a cheap train ticket from Osnabrück to Prague is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Osnabrück to Prague will cost around €100 if you buy it on the day, but the cheapest tickets can be found for only €50.
It's difficult to get from Osnabrück to Prague without transferring at least once.
ICE 208 · RJ 175
ICE 1053 · ICE 549 · RJ 385
ICE 206 · RJ 383
ICE 204 · RJ 177
ICE 202 · RJ 385
ICE 1053 · ICE 549 · RJ 385
ICE 204 · RJ 177
ICE 208 · RJ 175
ICE 206 · RJ 383
ICE 202 · RJ 385Omio recommends booking the bus as it is the most popular option from Osnabrück to Prague among Omio's users. If you are prioritising price, take the bus, with an average ticket price of €56 For those with little time, consider booking a flight, which has an average total journey time of 4h 39m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.2 - 0.5kg. Average ticket prices depend on the travel mode: a bus costs an average of €56, while a flight costs an average of €434.
Distance: 314 miles (506 km)
| Train | Most popular Bus | Flight | Driving |
|---|---|---|---|
€129 Average price | €56 Average price Cheapest | €434 Average price | €103 Average price (fuel + tolls) |
8h 14m Average total duration 7h 44m Onboard + 30m Additional time* | 11h 4m Average total duration 10h 34m Onboard + 30m Additional time* | 4h 39m Average total duration Fastest 2h 39m Onboard + 2h 0m Additional time* | 6h 50m Average total duration (door-to-door) |
0.2 - 0.5kg CO2 emissions Lowest | 0.5 - 1.3kg CO2 emissions | 1.5 - 3.0kg CO2 emissions | - CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Osnabrück to Prague:
A bus is €74 less than a train for this route with tickets for a train from Osnabrück to Prague costing on average €129.
A bus is €378 less than a flight for this route with tickets for a flight from Osnabrück to Prague costing on average €434.
Other travel options to Prague take longer:
Train takes on average 7h 44m.
Bus takes on average 10h 34m.
Tickets start at around €129 compared to roughly €103 in fuel and tolls — a saving of about €-26.26. The journey takes 7h 44m versus 6h 50m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
The table below shows live departures for Osnabrück to Prague trains for today, Friday, September 18. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
ICE 202 · RJ 385 | Delayed 1:23 PM Osnabrück Hbf | 8h02 | 7:32 PM 7:32 PMPrague hlavní nádraží | 1 transfer | |
ICE 1053 · ICE 549 · RJ 385 | Delayed 12:14 PM 1:53 PMOsnabrück Hbf | 7h32 | 7:32 PM 7:32 PMPrague hlavní nádraží | 2 transfers | |
| Saturday, September 19 | |||||
ICE 208 · RJ 175 | On time 7:23 AM Osnabrück Hbf | 7h52 | 3:15 PM Prague-Holešovice | 1 transfer | |
ICE 206 · RJ 383 | On time 9:23 AM Osnabrück Hbf | 8h02 | 5:25 PM Prague hlavní nádraží | 1 transfer | |
ICE 204 · RJ 177 | On time 11:23 AM Osnabrück Hbf | 7h52 | 7:15 PM Prague-Holešovice | 1 transfer | |
Find all the dates and times for this journey
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Trains from Osnabrück to Prague run on average 10 times per day, taking around 7h 44m. Cheap train tickets for this journey start at €33 but you can travel from only €24 by bus.
The earliest train runs at 00:30, the last at 23:41. The fastest train covers the 314 miles (506 km) distance in 6h 32m.
Distance 314 miles (506 km) |
Average train duration 7h 44m |
Cheapest ticket price €33 |
Trains per day 10 |
Fastest train 6h 32m |
First train 12:30 AM |
Last train 11:41 PM |
Cheapest Month May |
Cheapest Day Wed |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Sat |
Least Busy Day Sun |
Best time to book 1 day |
Discover the best of Prague — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Prague trip today.
Major museum of Czech history and natural sciences in a monumental Neo-Renaissance building overlooking Wenceslas Square.
Well-curated Jewish history museum across several historic sites. Important for understanding Prague's Jewish heritage and resilience.
Leading Czech art museum with medieval to modern works in a grand historic palace. Essential for fine art and decorative arts lovers.
Historic square at Prague's core, surrounded by Gothic and Baroque landmarks. A must for first-time visitors and classic city views.
Lively boulevard of Czech modern history, lined with shops and major buildings. Worth visiting for atmosphere and historic significance.
Romantic quarter of palaces, lanes, and church domes beneath Prague Castle. Ideal for wandering, photography, and quieter historic charm.
Slow-braised beef in a creamy root-vegetable sauce, usually served with bread dumplings. A classic Czech Sunday dish strongly linked to Bohemian home cooking.
Crisp roasted pork knuckle, often served with mustard, horseradish, and pickles. A hearty pub staple popular with Czech beer culture.
Roast pork with sauerkraut and dumplings. This iconic Czech combination is a cornerstone of traditional pub and family meals.
Traditional Czech restaurant and brewery by Prague Castle, praised for roast meats, dumplings, and polished historic interiors.
Upscale restaurant focused on Czech ingredients and game, with sophisticated service in an Art Nouveau municipal house setting.
Elegant Michelin-starred restaurant known for modern Czech tasting menus in a refined setting near the Vltava.
Moderate for Europe: transit is cheap, casual meals are reasonable, and hotels in the center can raise daily costs in peak season.
Service is often not included. Tip about 5-10% in restaurants, round up for cafes, and round up or add about 10% for taxis if service is good.
Official public transport app
Praha hlavní nádraží -> Václavské náměstí, Prague
Find answers to the most common questions about traveling from Osnabrück to Prague by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

Most Osnabrück to Prague trains use the Osnabrück Hbf to Praha hlavní nádraží station pair, with some services arriving at Praha-Holesovice. Use this guide to compare Osnabrück and Prague train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
Osnabrück Hbf has practical services for this route, including Wifi, Lockers, Shopping, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lounge, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, and Information Desk.
Food options include: Beykebab, Kochlöffel, Algarve Grill, Pizza Max
Wi-Fi is available at Osnabrück Hbf. ATMs are available at Osnabrück Hbf.
Ticket office support is available at Osnabrück Hbf. Information desks are available at Osnabrück Hbf.
Luggage storage is available at Osnabrück Hbf. Lost and found is available at the station.
Available at Osnabrück Hbf: Parking, Taxis, WC.
Available at Osnabrück Hbf: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Osnabrück Hbf.
Nearby hotels include Pension Haus Auf Dem Klushügel, Best Western Hotel Hohenzollern, Ibis Budget, Boardinghouse Villa Il Paradiso.
Osnabrück Altstadt has practical services for this route, including Wifi, Lockers, Shopping, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lounge, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, and Information Desk.
Food options include: McDonald's, Cafe Extrablatt, Cafe & Bar Celona, Café Mano Negra
Wi-Fi is available at Osnabrück Altstadt. ATMs are available at Osnabrück Altstadt.
Ticket office support is available at Osnabrück Altstadt. Information desks are available at Osnabrück Altstadt.
Luggage storage is available at Osnabrück Altstadt. Lost and found is available at the station.
Available at Osnabrück Altstadt: Parking, Taxis, WC.
Available at Osnabrück Altstadt: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Osnabrück Altstadt.
Nearby hotels include Romantikhotel Walhalla, Dom-Hotel, Hotel am Nikolaiort, Bergmann Boardinghouse.
Praha hlavní nádraží is 1 km from Prague city centre. Public transport options include:
Praha hlavní nádraží has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Shower, Lounge, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, Information Desk, and Luggage Carts.
Food options include: Restaurant Fantova Kavárna, Sushi Time
Free. ATMs are available in the train station.
Ticket office support is available at Praha hlavní nádraží. Information desks are located in the main hall.
Luggage storage is available at Praha hlavní nádraží. Lost and found is available at the station.
Available at Praha hlavní nádraží: Parking, Taxis, WC.
Available at Praha hlavní nádraží: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Praha hlavní nádraží: Elevators, ramps.
Nearby hotels include Hotel Esplanade Prague, Falkensteiner Hotel Maria Prag, Hotel City Central.
Praha-Holesovice is 2 km from Prague city centre. Public transport options include:
Praha-Holesovice has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, Information Desk, and Luggage Carts.
Food options include: Restaurant Na Kovárně, Cross Club
Free. ATMs are available in the train station.
Ticket office support is available at Praha-Holesovice. Information desks are located in the main hall.
Luggage storage is available at Praha-Holesovice. Lost and found is available at the station.
Available at Praha-Holesovice: Parking, Taxis, WC.
Available at Praha-Holesovice: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Praha-Holesovice: Ramps, restrooms.
Nearby hotels include Mama Shelter Prague, Plaza Alta Hotel, Hotel Belvedere.
Praha Masarykovo Nádraží has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, Information Desk, and Luggage Carts.
Food options include: Restaurant Kotleta, Café Imperial
Free. ATMs are available in the train station.
Ticket office support is available at Praha Masarykovo Nádraží. Information desks are located in the main hall.
Luggage storage is available at Praha Masarykovo Nádraží. Lost and found is available at the station.
Available at Praha Masarykovo Nádraží: Parking, Taxis, WC.
Available at Praha Masarykovo Nádraží: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Praha Masarykovo Nádraží: Ramps.
Nearby hotels include Hotel Kings Court, Grand Hotel Bohemia, Hotel Paris Prague.
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